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A histopathological and histochemical study of appearance of mucous cells in the salivary duct epithelium surrounding mucous cysts
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Abstracts
vimentin (⫹/⫺), CD 34 (⫺), S100 (⫺), chromogranin and sinaptofiscin (⫺); ACT was made showing tumor in kidney, so we conclude as a metastatic renal carcinoma in the mandible. Conclusion: The metastases in oral cavity are rare lesions but must be known in working diagnosis in painful diseases, immunohistochemistry is helpful for diagnosis.
HEALING PROCESS OF AUTOGRAFTS AND ALLOGRAFTS IN RABBITS’ ILIAC CREST Weinfeld I1, Carrilho GPB2 - 1UNISA, 2INSTITUTO IMPLANTEPERIO The use of allografts as bone substitutes has increased in implant dentistry despite its lack of scientific evidence. This study compared bone healing dynamics of onlay allografts and autografts. Ten rabbits were submitted to an autograft and an allograft at the iliac crest. Over the following 18 weeks, intravital staining with four different fluorochromes was performed. Then, grafts were prepared for sectioning for further fluorescence microscopy analysis and histometric evaluation. Bone density (BD) and bone to fixation screw contact (BIC) were analyzed. Autografts presented the following results for fluorochrome labeling: 0.24⫾ 0.41% (AL), 3.76⫾0.93% (CB), 3.24⫾0.89% (CA) and 1.25⫾ 1.21% (OT), and allografts: 0.24⫾0.45% (AL), 3.80⫾1.12% (CB), 3.21⫾1.71% (CA) and 1.25⫾0.75% (OT). BD was 55.90⫾7.00% and 44.72⫾6.53% for autografts and allografts, respectively. BIC was 47.04⫾15.85% for autografts and 44.55⫾13.71% for allografts. Allografts and autografts showed slower osteogenic activity at the initial healing stages. Although allografts and autografts presented similar BIC and fluorochrome incorporation values, allograft BD was statistically poorer.
IMPACT OF BOLUS USED IN THE TREATMENT OF IRREGULAR FACIAL SURFACE IN RADIATION THERAPY Rodrigues GHC1, Alves FA1, Prado JD1, Pellizzon CAP2, Boccaletti K2, Marcicano A2, Jaguar GC1 - 1HOSPITAL AC CAMARGO - ESTOMATOLOGIA, 2HOSPITAL AC CAMARGO - RADIOTERAPIA Background: Radiation treatment involving irregular facial contours is complex because the isodoses lines become skewed. The use of bolus as a tissue-equivalent field compensation is discussed in the literature. This material is made to fit the irregular surface compensating the topology and creating an even area. Objective: To evaluate the effects of a wax bolus as a compensator material during radiotherapy. Study design: A 70-year-old man with an extensive irregular facial topography due to a resection of left external ear canal carcinoma infiltrating parotid gland was submitted to computed tomography for radiation treatment planning with and without the use of the bolus. Results: Dosimetric analysis showed that the irradiation dose in the tumor volume was more precise with the use of this device. Conclusions: This study showed that the wax bolus is a simple and useful device to treat nonplanar surface and emphasized the importance of multidisciplinary team during radiotherapy.
ORAL FOCAL MUCINOSIS: CASE REPORT Pereira HSC1, Póvoa RC1, Pires FR2, Bahia TP2, Maciel RM2, Ramos MEB2, Israel MS2 - 1UERJ - FACULDADE DE ODONTO-
October 2012 LOGIA, 2UERJ - DEPARTAMENTO DE DIAGNÓSTICO E CIRURGIA Oral focal mucinosis, an oral counterpart of cutaneous focal mucinosis, is a rare disease of unknown etiology. Its pathogenesis may be due to overproduction of hyaluronic acid by fibroblast at the expense of collagen production, resulting in focal myxoid degeneration of connective tissue primarily affecting the mucosa overlying bone. It has no distinctive clinical features, since the diagnosis is solely based on histopathological features. The aim of this study is to report a case of oral focal mucinosis and discuss clinicopathological features and different diagnosis of myxomatous lesions of the oral cavity. A 42 year-old women had a large epulis on gingiva that kept growing for 2 months. The oral examination showed a nodule, with normal color, smooth surface, hard in the consistency, with no symptoms, had a size of 2 centimeters and was located in gingival between the elements 24 and 25. The biopsy allowed the focal mucinosis diagnosis. After 1 year no signs of recurrence were noted.
A HISTOPATHOLOGICAL AND HISTOCHEMICAL STUDY OF APPEARANCE OF MUCOUS CELLS IN THE SALIVARY DUCT EPITHELIUM SURROUNDING MUCOUS CYSTS Takanashi H1, Utsunomiya T2, Yamamoto H2 - 1NIHON UNIVERSITY SCHOOL OF DENTISTRY AT MASTUDO - ORAL PATHOLOGY, 2NIHON UNIVERSITY SCHOOL OF DENTISTRY AT MATSUDO - ORAL PATHOLOGY (Objective) The purpose of this study was to histopathologically and histochemically investigate the localization of mucous cells in the salivary glands surrounding mucous cysts (26 cases) compare to the normal salivary glands. (Study design) Mucous cysts, definitively diagnosed at our department (26 cases), were observed with hematoxylin-eosin and PAS-alcian blue pH 2.5 stainings and the rates of the mucous cells were calculated. (Results and conclusion) Histopathologically, mucous cells with slightly hematoxylic cytoplasm were observed in the salivary duct epithelium surrounding mucous cysts. The rates of mucous cells, bluish stained with alcian blue, pH 2.5 were higher than those of the normal salivary glands. The rates of mucous cells were also peaked at seventh decade women. The results suggested that the appearance of mucous cells, involved sulfomucin, might be resulted from a metaplastic change of the duct epithelium associated with local environment of the formation of mucous cysts.
GINGIVAL LOW-GRADE MYOFIBROBLASTIC SARCOMA: CASE REPORT González JS1, Valdéz CAM2, Morán SC3, Meza GA4 - 1UNIVERSIDAD QUETZALCÓALT EN IRAPUATO - PATHOLOGY, 2INSTITUTO NACIONAL DE CANCEROLOGÍA - PATHOLOGY, 3UNIVERSIDAD QUETZALCÓATL EN IRAPUATO - ORAL AND MAXILLOFACIAL SURGERY, 4HEAD AND NECK ONCOLOGY SURGERY Introduction: Low-grade myofibroblastic sarcoma (LGMS) is a neoplasm of atypical myofibroblasts which has only recently become clearly defined. It represents a rare entity with a predilection for the head and neck region. The differential diagnosis of LGMS includes a number of benign and malignant spindle cell neoplasms. Lack of obvious cytological atypia may complicate the diagnostic process.
e88
Abstracts
vimentin (⫹/⫺), CD 34 (⫺), S100 (⫺), chromogranin and sinaptofiscin (⫺); ACT was made showing tumor in kidney, so we conclude as a metastatic renal carcinoma in the mandible. Conclusion: The metastases in oral cavity are rare lesions but must be known in working diagnosis in painful diseases, immunohistochemistry is helpful for diagnosis.
HEALING PROCESS OF AUTOGRAFTS AND ALLOGRAFTS IN RABBITS’ ILIAC CREST Weinfeld I1, Carrilho GPB2 - 1UNISA, 2INSTITUTO IMPLANTEPERIO The use of allografts as bone substitutes has increased in implant dentistry despite its lack of scientific evidence. This study compared bone healing dynamics of onlay allografts and autografts. Ten rabbits were submitted to an autograft and an allograft at the iliac crest. Over the following 18 weeks, intravital staining with four different fluorochromes was performed. Then, grafts were prepared for sectioning for further fluorescence microscopy analysis and histometric evaluation. Bone density (BD) and bone to fixation screw contact (BIC) were analyzed. Autografts presented the following results for fluorochrome labeling: 0.24⫾ 0.41% (AL), 3.76⫾0.93% (CB), 3.24⫾0.89% (CA) and 1.25⫾ 1.21% (OT), and allografts: 0.24⫾0.45% (AL), 3.80⫾1.12% (CB), 3.21⫾1.71% (CA) and 1.25⫾0.75% (OT). BD was 55.90⫾7.00% and 44.72⫾6.53% for autografts and allografts, respectively. BIC was 47.04⫾15.85% for autografts and 44.55⫾13.71% for allografts. Allografts and autografts showed slower osteogenic activity at the initial healing stages. Although allografts and autografts presented similar BIC and fluorochrome incorporation values, allograft BD was statistically poorer.
IMPACT OF BOLUS USED IN THE TREATMENT OF IRREGULAR FACIAL SURFACE IN RADIATION THERAPY Rodrigues GHC1, Alves FA1, Prado JD1, Pellizzon CAP2, Boccaletti K2, Marcicano A2, Jaguar GC1 - 1HOSPITAL AC CAMARGO - ESTOMATOLOGIA, 2HOSPITAL AC CAMARGO - RADIOTERAPIA Background: Radiation treatment involving irregular facial contours is complex because the isodoses lines become skewed. The use of bolus as a tissue-equivalent field compensation is discussed in the literature. This material is made to fit the irregular surface compensating the topology and creating an even area. Objective: To evaluate the effects of a wax bolus as a compensator material during radiotherapy. Study design: A 70-year-old man with an extensive irregular facial topography due to a resection of left external ear canal carcinoma infiltrating parotid gland was submitted to computed tomography for radiation treatment planning with and without the use of the bolus. Results: Dosimetric analysis showed that the irradiation dose in the tumor volume was more precise with the use of this device. Conclusions: This study showed that the wax bolus is a simple and useful device to treat nonplanar surface and emphasized the importance of multidisciplinary team during radiotherapy.
ORAL FOCAL MUCINOSIS: CASE REPORT Pereira HSC1, Póvoa RC1, Pires FR2, Bahia TP2, Maciel RM2, Ramos MEB2, Israel MS2 - 1UERJ - FACULDADE DE ODONTO-
October 2012 LOGIA, 2UERJ - DEPARTAMENTO DE DIAGNÓSTICO E CIRURGIA Oral focal mucinosis, an oral counterpart of cutaneous focal mucinosis, is a rare disease of unknown etiology. Its pathogenesis may be due to overproduction of hyaluronic acid by fibroblast at the expense of collagen production, resulting in focal myxoid degeneration of connective tissue primarily affecting the mucosa overlying bone. It has no distinctive clinical features, since the diagnosis is solely based on histopathological features. The aim of this study is to report a case of oral focal mucinosis and discuss clinicopathological features and different diagnosis of myxomatous lesions of the oral cavity. A 42 year-old women had a large epulis on gingiva that kept growing for 2 months. The oral examination showed a nodule, with normal color, smooth surface, hard in the consistency, with no symptoms, had a size of 2 centimeters and was located in gingival between the elements 24 and 25. The biopsy allowed the focal mucinosis diagnosis. After 1 year no signs of recurrence were noted.
A HISTOPATHOLOGICAL AND HISTOCHEMICAL STUDY OF APPEARANCE OF MUCOUS CELLS IN THE SALIVARY DUCT EPITHELIUM SURROUNDING MUCOUS CYSTS Takanashi H1, Utsunomiya T2, Yamamoto H2 - 1NIHON UNIVERSITY SCHOOL OF DENTISTRY AT MASTUDO - ORAL PATHOLOGY, 2NIHON UNIVERSITY SCHOOL OF DENTISTRY AT MATSUDO - ORAL PATHOLOGY (Objective) The purpose of this study was to histopathologically and histochemically investigate the localization of mucous cells in the salivary glands surrounding mucous cysts (26 cases) compare to the normal salivary glands. (Study design) Mucous cysts, definitively diagnosed at our department (26 cases), were observed with hematoxylin-eosin and PAS-alcian blue pH 2.5 stainings and the rates of the mucous cells were calculated. (Results and conclusion) Histopathologically, mucous cells with slightly hematoxylic cytoplasm were observed in the salivary duct epithelium surrounding mucous cysts. The rates of mucous cells, bluish stained with alcian blue, pH 2.5 were higher than those of the normal salivary glands. The rates of mucous cells were also peaked at seventh decade women. The results suggested that the appearance of mucous cells, involved sulfomucin, might be resulted from a metaplastic change of the duct epithelium associated with local environment of the formation of mucous cysts.
GINGIVAL LOW-GRADE MYOFIBROBLASTIC SARCOMA: CASE REPORT González JS1, Valdéz CAM2, Morán SC3, Meza GA4 - 1UNIVERSIDAD QUETZALCÓALT EN IRAPUATO - PATHOLOGY, 2INSTITUTO NACIONAL DE CANCEROLOGÍA - PATHOLOGY, 3UNIVERSIDAD QUETZALCÓATL EN IRAPUATO - ORAL AND MAXILLOFACIAL SURGERY, 4HEAD AND NECK ONCOLOGY SURGERY Introduction: Low-grade myofibroblastic sarcoma (LGMS) is a neoplasm of atypical myofibroblasts which has only recently become clearly defined. It represents a rare entity with a predilection for the head and neck region. The differential diagnosis of LGMS includes a number of benign and malignant spindle cell neoplasms. Lack of obvious cytological atypia may complicate the diagnostic process.