A method for studying variations in coronary inflow during a series of cardiac cycles, or for determining inflow rates generally

A method for studying variations in coronary inflow during a series of cardiac cycles, or for determining inflow rates generally

WSTRACTS Gouley, B. A., Bellet, Samuel, and McMillan, cardium. Arch. Int. Med. 51: 244,X)33. SG!) Thomas M.: Tuberculosis of the Myo- Six casts ...

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.WSTRACTS

Gouley, B. A., Bellet, Samuel, and McMillan, cardium. Arch. Int. Med. 51: 244,X)33.

SG!)

Thomas M.: Tuberculosis

of the Myo-

Six casts of tuberculosis of the myocardium are reported. Four of the patients were males and two were females. Four were negroes and two were white people. The ages of the patients were 16, 16, 26, 46, -31 and 17 years. These cases represent the different types of tubclrculous myocarditis that have hitherto been rcportetl. A simple classification is suggested, based on the mode of dissemination and the type of lesion; (a) myocardial tuberculosis, secondary to mediastinal glandular and pericardial tuberculosis and (b) as part of systemic miliary tuberculosis. Involvement of the coronary arteries in one case in an unusual degree and in other cases to slight degree is reported, and the various t,ypcs of tuberculous arteritis are described: (a) diffuse tuherculous arteritis, involving all the I-csscl coats; (b) intima1 tubercle without involvement of other vessel coats as a result of blood borne infection; and (c) a type of arterial involvement by tuberculosis (contact arteritis) previously not described in the heart., affecting not only the small but also the large coronary arteries and leading to narrowing of their lumens and even to conlplcte occlusion. The occasional similarity of rheumatic and tuberculous myocarditis is noted, and a differential diagnosis is outlined. The probability of ectopic rhythm resulting from the tuberculous infiltration of the right auricle is discussed.

Horton, Bayard T., and Brown, George Women. Arch. Int. Med. 50: 884? 1932.

E.: Thromboangiitis

Obliterans

Among

Although approximately 700 cases of thromboangiitis obliterans have been observed among men at the Mayo Clinic, the present report of 10 cases is the first series among women to be put on record. The diagnosis in three of these cases was proved by a study of the pathological changes in the occluded arteries and veins. The authors are of t,he opinion that this disease has a higher incidence among women than is brought out by this study. The failure to recognize the disease is due probably to tho facts that it is relatively mild among women and that the diagnosis is overlooked. Three of the patients in the series were of Jewish extraction; their disease was more severe than in the 7 gentiles. A similar clinical impression was gained in the series of men; the disease of the Jewish patients seemed more serious and intense than that in the other races. Four patients were treated hy bilateral lumbar sympathetic ganglionectomy; one One paof these also had bilateral rervic,othoracic sympathetic ganglionectomy. tient had an amputation of the right leg and the other patients were treated medically. The treatment, for the most part, has proved satisfactory. The disease among women apparently runs a similar but definitely milder course than among men.

Stehle, R. L.: A Method for Studying Variations in Coronary Inflow During a Series J. Pharmacol. & of Cardiac Cycles, or for Determining Inflow Rates Generally. Exper.

Therap.

46:

471, 1932.

The method is described fication of the Langendorff

for use as outlined method.

in the succeeding

paper.

It is a modi-

Stehle, R. L., and Melville, K. I. : The Influence of the Heart Beat Upon the Flow of Blood Into the Coronary Arteries. J. Pharmacol. & Exper. Therap. 46: 477, 1933. The method of studying coronary inflow described in the preceding paper has been applied to the rabbit’s heart. The results show that the inflow begins late in diastole and continues into systole. It is not restricted to diastole or to systole. In contradistinction to observations by Hochrein, these experiments indicate that the maxThe authors imum flow is not restricted to an instant but la& through a definite period.