Abstracts read by title

ABSTRACTS

READ

BY

TITLE

107. The development oJ re/tex control oJ cardiac Junction in the newborn lamb

CARDIOLOGY, PULMONARY PHYSIOLOGY

S. Evans Downing,r Thomas H. Gardner, ~ and Norman S. Talner, Departments of Pathology and Pediatrics, Yale University School of Medicine, New Haven , Conn.

102. Hypoglycemia and congestive heart failure George Benzing, III, ~ Samuel Kaplan, George Hug, ~" and George Nagao, e Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio

108. Aortic aneurysm in association with coarctation of the aorta: A pediatric problem

103. Morbidity of "non-cardiac disease" in schoolchildren

Kathryn H. Ehlers, ~ Mary Allen Engle, Harry L. Stein,"~ and S. Frank Redo, ~ Cornel1 University Medical College, New York, N. Y.

Abraham B. Bergman~ and Stanley J. Stamm, "x" Children's Orthopedic Hospital and Medical Center and University of Washington School of Medicine, Seattle, Wash. Introduced by Robert P. Igo

109. Quantitative studies of acid-base displacement in chronic respiratory acidosis

104. Fetal and neonatal lamb lung phospholipid metabolism

K. Engel, "~ R. B. Dell, ~ W. J. Rahill, ~ C.

R. Denning,~ and R. W. Winters, Babies Hospital, New York, N. Y.

Nobukazu Chida, ~ Forrest H. Adams, and Mary Montgomery,r University of California, Los Angeles, Calif.

110. Inclusion cell disease in children after cardiovascular surgery

105. Tolazoline in the treatment of cystic iqbrosis

Paul Y. Ertel, ~ Inta J. Ertel, ~ and Aaron M. Stern, ~ University of Michigan, Ann Arbor, Mich. Introduced by Albert V. Hennessy

Ernest K. Cotton,r University of Colorado School of Medicine, Denver, Colo. Introduced by Henry K. Silver

111. Rate of growth after corrective surgery in children with ventricular septal defect and marked growth failure

106. Mist tent nebulization therapy of the chronic obstructive pulmonary lesion of cystic ]ibrosis Carl F. Doershuk, C. Terrence Gillespie, Samuel Spector, and LeRoy W. Matthews, Western~ Reserve University School of Medicine, Cleveland, Ohio

Robert H. Feldt, ~ Edward J. O'Connell,~ Gunnar B. Stickler, and William H. Weidman, Mayo Clinic and Mayo Foundation, Rochester; Minn. 989

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Society for Pediatric Research

112. Separated renal function studies Daniel S. Finisher, St. Christopher's Hospital for Children and Temple University School of Medicine, Philadelphia, Pa.

113. Response of pulmonary hypertension to unilateral banding of pulmonary artery Richard L. Fowler, Bert A. Glass, ~ and

Jack C. Geer, ~ Louisiana State University School of Medicine, New Orleans, La.

114. Internal jugular vein sampling for quantitatlon of cardiac output by dye dilution curves Donald A. Girod ~ and Eugene L. Petry, ~"

Indiana University School of Medicine, Indianapolis, Ind. Introduced by Paul R. Lurie

151. The effect of sedatives on systemic and pulmonary hemodynamics Stanley Goldberg, ~ Leonard Linde, Peter Gaal, "x" and Gerald Berman, ~ University of California School of Medicine, Los Angeles, Calif.

116. Morphogenesis of pulmonary lesions in vagotomized rats Victor E. Goldenberg, ~ Sheldon C. Sommers, ~: and Sue Buckingham, Columbia University School of Medicine, New York, N.Y.

117. Impulse formation and conduction in the heart of the developing chick embryo Gershon Halt "~ and Richard H. Lieata, "~ Congenital Heart Disease Research and Training Center, Hektoen Institute, Chicago, Ill. Introduced by Abraham M. Rudolph

118. Endocardiomyopathy in children: Observations on mechanism of pulsus alternans L. C. Harris,"* Q. X. Nghiem,'* M. H.

November 1966 Schreiber,':" and J. M. Wallace, * University of Texas Medical Branch, Galveston, Texas Introduced by C. W. Oacschner

119. Cardiovascular involvement associated with congenital rubella Alois R. Hastreiter, ~ Geremia Pujatti, ~ Ronald L. van der Horst, ~ Bahman Joorabehi, "x" Gregorio Patacsil, ~ Robert A. Miller, and John H. Sever, ~" University

of Illinois College of Medicine and Cook County Children's Hospital, Chicago, Ill.

120. Exercise responses in childhood asthma E. M. Heimlieh, Lawrence Strick, ~ and R. J. Busser, ~ U.C.L.A. School of Medicine, Los Angeles, Calif.

121. Cardiac dysfunction in mild pulmonlc stenosis Mary J. Jesse, ~ o . Robert Levine, * Harold S. Goldman, ~ John O. Burris, ~ and Sidney Blumenthal, ~' Babies Hospital, New York, N. Y. Introduced by Katherine Sprunt

122. Ventilation and respiratory gas transfer of infants with pulmonary overcirculation Martin H. Lees, "~ Benjamin B. Ross, "x" Clifton Way, ~ and Thomas MeKean, "x"

University of Oregon Medical School, Portland, Ore. Introduced by Richard Goldbloom

123. Characteristics of periodic breathing in premature infants Edward F. Lenoski ~ and Chester Hyman, ~ University of Southern California School of Medicine and Los Angeles County General Hospital, Los Angeles, Calif. Introduced by John A. James

124. The effect of hypoxia and of atelectasls on the formation of pulmonary edema in intact dogs

Volume 69 Number 5 part 2

O. Robert Levine,~ Robert B. Mellins, "~ and Alfred P. Fishman,"z Columbia-Presbyterian Medical Center, New York, N. Y. Introduced by Edward C. Curnen

125. The effect of congenital heart disease on mental development Leonard M. Linde, Beatrice Rasof,* and Olive J. Dunn, "~ University of California School of Medicine, Los Angeles, Calif.

126. Hemodynamics of preductal coarctation in early infancy Joshua Lynfield, Peter Kottmeier,"~ and Preecha Vichitbandha, "x"Downstate Medical Center, Brooklyn, N. Y.

Infarction of papillary muscles in symptomatic aortic stenosis in infancy 127.

James H. Moller,"~ Ahmad Nakib,* and Jesse E. Edwards,* University of Minnesota Hospital, Minneapolis, Minn., and the Charles T. Miller Hospital, St. Paul, Minn. Introduced by Ray C. Anderson

128. Cardiac volume in children and adolescents and its value in assessing severity of rheumatic mltral insufficiency Q. x . Nghiem,~ M. H. Schreiber,* and L. C. Harris, "x" University of Texas Medical Branch, Galveston, Texas Introduced by C. W. Daeschner

129. An unusual form of aortic stenosis: Clinical, hemodynamic, radiographic, and anatomic data Eugene L. Petry, "~ Paul R. Lurie, and Gerald J. Kurlander,* Indiana University School of Medicine, Indianapolis, Ind.

130. Poudrage via thoracentesis and pericardiocentesis: A nonsurgical approach to increasing collateral circulation

Abstracts read by title 99 1

William J. Rashkind and Llynda Hinds,* Children's Hospital of Philadelphia, Philadelphia, Pa.

131. The electrocardiogram in children with acute respiratory tract diseases Lewis P. Scott, * Margaret F. Gutelius,~ and Robert H. Parrott, Children's Hospital of the District of Columbia, Washington, D. C.

132. Toxic effects of oxygen under high pressure in newborn and adult mice Donald R. Sperling, ~" Jose Strauss, Anthony V. Beran,* and George A. Misrahy,t University of California-California College of Medicine, University of Southern California School of Medicine, and Childrens Hospital of Los Angeles, Los Angeles, Calif. tDeceased.

133. In vitro study of ciliary motility: Asymmetrical ciliary beat associated with sera of patients with cystic fibrosis Alexander Spock,* Hans Heick,~ Hertha Cress, ~" and William Logan,~ Duke University Medical Center, Durham, N. C.

134. Ultrastructure of the intraglandular secretions of the labial minor salivary glands from children with cystic fibrosis Laura Sweneyr and Warren J. Warwick, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minn.

135. Anatomically corrected transposition of the great arteries Richard Van Praagh ~ and Stella Van Praagh,* Children's Hospital Medical Center, Boston, Mass. Introduced by Fred S. Rosen

99 2 Society for Pediatric Research 136. Cardiac and vascular reactivity in atopic and nonatopic children Hubert S. Varonier e and William W. Hahn, ~ Children's Asthma Research Institute and Hospital, Denver, Colo. Introduced by C. Henry Kempe

137. Immunoglobulins in cystic fibrosis Brent W. Wagstaff,e Edwin W. Aldous, e Marvin L. Rallison, e and Douglas C. Heiner, University of Utah, College of Medicine, Salt Lake City, Utah

138. Mucoid impaction of the bronchi in cystic fibrosis William W. Waring, e C. Hal Brunt, e and Bettina C. Hilman, e Tulane University School of Medicine and Louisiana State University School of Medicine, New Orleans, La. Introduced by Ralph V. Platou

139. Effect of severe, chronic hypoxia on closure of the ductus arteriosus in newborn swine Muriel D. Wolfe and Richard D. Rowe, The Johns Hopkins University School of Medicine, Baltimore, Md.

140. Hypoxemia caused by perfusion of nonventilated lung in children with status asthmaticus David W. Wood, ~ John J. Downes, e and H. Leeks, e Divisions of Allergy and Anesthesiology, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, Pa. Introduced by George Polgar

DEVELOPMENTAL BIOLOGY

141. Biologic influence of early high-caloric feeding of low birth weight infants Billy F. Andrews, e Larry N. Cook, e and

November 1966 Frank T. Falkner~ University of Louisville School of Medicine, Louisville, K y .

142. The prognostic value of cord serum protein determinations in the newborn Billy F. Andrews, "x"Griffith Quinby,e and Patricia P. Thomas, e University of Louisville School of Medicine, Louisville, Ky. Introduced by Frank T. Falkner

143. Clinical pharmacology of the penicillins in premature infants Stanton G. Axline, e Harold J. Simon,e and Sumner J. Yaffe, School of Aerospace Medicine, Brooks AFB, Texas, Stanford University School of Medicine, Palo Alto, Calif., and School of Medicine, State University of New York at Buffalo, Buffalo, N. Y.

144. Catecholamlne excretion in neonatal hypoglycemia Lester Baker, e Robert Kaye, A. L. N. Prasad, e and E. Eugene Kunzman,e Children's Hospital of Philadelphia and the University of Pennsylvania, Philadelphia, Pa.

145. Serum levels of methicillin and ampicillin in newborn and premature infants in relation to postnatal age Roger W. Boe,e Christopher P. S. Williams, "x" and Thomas K. Oliver, Jr., University of Washington School of Medicine, Seattle, Wash.

146. Acidosis and disease in premature infants weighing 0.75 to 7.25 kilograms G. Bucci, ~ M. Mendicini, e A. Ceccamea, e G. Iannaceone,e P. G. Savignoni, e A. Scalamandre,e and M. Orzalesi, e University of Rome, Rome, Italy Introduced by C. A. Smith

147. Newborn sucking and environmental stimulation

Volume 69 Number 5 part 2

Donald J. Cohen, "x"Yale University School of Medicine, New Haven, Conn. Introduced by Louis Gluek

148. Early versus late feeding of premature infants: Effects on blood sugar and gross motor activity Marvin A. Eisengart, ~ Louis Gluck, and William Kessen, "~ Yale University School of Medicine, New Haven, Conn.

149. Blood oxygen content of apneic infants during resuscitation Donald V. Eitzman, I. H. Gessner, ~ H. Prystowsky, ~ V. Stenger, ~ and J. Blechnet, "x" University of Florida College of Medicine, Gainesville, Fla.

150. Early versus late cord clamping: Hemodynamic and asphyxial effects Leonard F. Fagan, ~ James E. Bowers, ~ and Thomas A. Helmrath, "x" St. Louis University School of Medicine and Cardinal Glennon Memorial Hospital, St. Louis, Mo.

Introduced by Arthur E. MeElfresh

151. Metabolic effects of sodium salicylate on the hearts of chick and mouse embryos Ira H. Gessner, ~ H a r r y Bostr6m,'~! and K. Sune Larsson, ~x"University of Florida College of Medicine, Gainesville, Fla., and Wenner-Gren Institute, Stockholm, Sweden. Introduced by Richard T. Smith

152. A comparison of the nonspecific inflammatory response in premature and term infants Joan E. Hodgman, "~ Robert I. Freedman, ~: and Richard M. Galinson, ~ University of Southern California School of Medicine, and Los Angeles County General Hospital, LosAngeles, Calif. Introduced by Paul F. Wehrle

Abstracts read by title 9 9 3 153. Acid-base characteristics of arterial blood and cerebrospinal fluid in fetal and newborn lambs W. Alan Hodson, ~ Axel Fenner, "x" George Brumley, ~ and Victor Chernick, ~" The Johns Hopkins University School of Medicine, Department of Pediatrics, Baltilnore, Md. Introduced by Mary Ellen Avery

154. Development of intestinal beta-galactosidase and beta-glucuronidase in the newborn David Y.-Y. Hsia, Northwestern Medical School, Chicago, Ill.

155. Morphologic observations on development of the microvasculature in infancy Stella B. Kontras "X"and Joann G. Bodenbender, ~" Ohio State University College of Medicine, Columbus, Ohio Introduced by Bruce D. Graham

156. The effects of environmental temperature and oxygen concentration on llmb blood flow of premature infants as measured with the capacitance plethysmograph Edward F. Lenoski "~and Chester Hyman, "z University of Southern California School of Medicine, Los Angeles, Calif.

157. Blood pressure and flow in the newborn and in infants with the respiratory distress syndrome Henry Levison, ~ Langford Kidd, ~" and Paul R. Swyer, Research Institute of the Hospital for Sick Children and the Department of Paediatrics, University of Toronto, Toronto, Canada

158. The effects of milk solute intake on urinary cast excretion in premature infants Michael L. MeCann ~" and Robert Schwartz, Western Reserve University

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Society [or Pediatric Research

School of Medicine and Cleveland Metropolitan General Hospital, Cleveland, Ohio

159. Fetal life study--prospective experience with piperazine derivative antinausea drugs in early pregnancy and congenital malformations and survival Gilbert W. Mellin, Columbia University College of Physicians and Surgeons and Babies Hospital, New York, N. Y.

160. The influence of glucose metabolism on prenatal development Richard L. Naeye,"x" University of Vermont, College of Medicine, Burlington, Vt. Introduced by Jerold Lucey

161. Membrane-diffuslng capacity and pulmonary capillary blood volume in newborn infants Nicholas M. Nelson, Klaus P. Riegel, "~" Christopher H. Nourse, "x" and Ruth B. Cherry,"x" Harvard Medical School, Boston, Mass.

162. Small-for-dates neonates: Early statural growth A. Frederick North, Jr., "~ University of Rochester, Rochester, N. Y. Introduced by Robert J. Haggerty

163. Factors influencing maternal-fetal pO~ and pCO~ transfer G. Rivard, ~" E. Motoyama,~' F. M. Acheson,~ and C. D. Cook, Department of Pediatrics and Division of Anesthesiology, Yale Medical School, New Haven, Conn.

164. Late neonatal acidosis in premature infants Richard J. Schain ~ and Kay O'Brien/r University of Nebraska College of Medicine, Omaha, Neb. Introduced by Gordon Gibbs

November 1966

165. The metabolic response to cold in sick and premature newborn infants Jon W. Scopes,~ Nuffield Research Unit, Institute of Child Health of London University, Hammersmith Hospital, London, England Introduced by William Silverman

166. Nitrous oxide as a possible teratogen in experimental mammals-a prdiminary report Thomas H. Shepard, B. Raymond Fink,~ and Richard J. Blandau,* University of Washington, Seattle, Wash.

167. A central collecting laboratory for human embryos as a teratologic tool Thomas H. Shepard and Ronald J. Lemire, "x"University of Washington, Seattle, Wash.

168. Activity of the newborn infant: Continuous recording by means of an activity bassinet Artemis P. Simopoulos, -x" Marion V. Miles, ~" and Pierre Severyns, ~ Children's Hospital of the District of Columbia, Washington, D. C. Introduced by Wellington Hung

169. Persistent patency of the ductus venosus Blanca Smith, ~ Diane Hanson,"x" and Charles Reiner, ~ The Columbus Children's Hospital, Columbus, Ohio, and National Institutes of Health, Bethesda, Md. Introduced by William A. Newton, Jr.

170, Chronic intrauterine studies in lambs Mildred Stahlman, F. M. Shepard, ~ Willard Blankenship,~ and Vildan Erkan, r Vanderbilt University School of Medicine, Nashville, Tenn.

Volume 69 Number 5 part 2

171. A controlled trial o] negative-pressure-assisted ventilation in respiratory distress syndrome Paul R. Swyer, Lydia Linsao,"~ Albert Aaron, r and Henry Levison,~ Research Institute of The Hospital for Sick Children and the Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada

172. Normally occurring reducing sugars in the urine of the newborn infant Mauriee Teitel ~ and Iris Borman, ~ North Shore Hospital, Stanley J. Lagin Laboratory, Manhasset, N. Y. Introduced by Alfred Florman

173. Pulmonary oxygen toxicity in a premature infant D. W. Thlbeault, "~ J. W. C. Hagstrom, "~ and P. A. M. Auld, Cornell University Medical College, New York, N. Y.

174. Relation of serum insulin and plasma-free fatty acids to glucose tolerance on the first day o/ life J. Raymond Tiernan, "x"Margaret L. Kernball, ~ Clement A. Smith, and J. Stuart Soeldner, ~ Harvard Medical School, Boston, Mass.

175. The pattern of physiologi c jaundice in the Sioux Carl W. Trygstad ~" and Clayton H. McCraeken, "x" National Institutes of Health and Division of Indian Health, United States Public Health Service Introduced by James F. Bosnia

176. Effect of pbenoxybenzamine hydrochloride (dibenzylene) on nonshivering thermogenesis in newborn rats Stanley C. Ushinski, ~ Children's Hospital and the University of Pittsburgh School of Medicine, Pittsburgh, Pa. Introduced by P. M. Taylor

Abstracts read by title 99 5

177. Tolbutamide tolerance test in infants of diabetic mothers Mutya S. A. Velasco, "~ Elsa P. Paulsen, and Lee Richenderfer, ~ Albert Einstein College of Medicine, New York, N. Y.

178. Normal cellular growth in rat and human placenta Myron Winick, ~ Anthony Coscia, r and Adele Noble, ~ Cornel l University Medical College, New York, N. Y. Introduced by W. W. MeCrory ENDOCRINOLOGY

179. Percutaneous absorption of hydrocortisone in children Thomas Aceto, Jr., "~ Barry I. Felnblatt, "z Gordon D. Beckhorn, ~" and Erika Bruek, Department of Pediatrics, State University of New York at Buffalo, Buffalo, N. Y.

180. Model for the measurement by radioimmunoassay of the endogenous secretion rate of a hormone Peter A. J. Adam, ~ David Link, ~ David Kornhauser, "x"and Robert Schwartz, Western Reserve University School of Medicine and Cleveland Metropolitan General Hospital, Cleveland, Ohio

181. Plasma insulin and growth hormone levels in juvenile diabetes mellitus before treatment and during partial remission Lester Baker, ~ Robert Kaye, and Allen W. Root, "~ Children's Hospital of Philadelphia and the University of Pennsylvania, Philadelphia, Pa.

182. Estrogen levels in urine and tumor of 2-year-old girl with granulosa cell tumor Carl Beling"~ and Maria New, "x"The New York Hospital-Cornell Medical Center, New York, N. Y. Introduced: by Wallace W. McCrory

99 6 Society for Pediatric Research

183. Sex and susceptibility to Coxsackie B 1 virus infection in the adult mouse Sumner Berkovich and Milton Ressel,~ Downstate Medical Center, Brooklyn, N.Y.

184. Fasting and postprandial plasma growth hormone levels in normal children and their relationship to growth Michael F. Brysonff Don S. Schalch,~"and Frank Sehultz, "x" University of Rochester School of Medicine, Rochester, N. Y. Introduced by Gilbert B. Forbes

185. Adrenal toxicity associated with the administration of amino glutethimide Alvro M. Camacho, "x" Ralph Cash, "x" A. Joseph Brough,~ R. Sidney Wilroy,"x" and James R. Givens,"' University of Tennessee School of Medicine, Memphis, Tenn., and Wayne State University School of Medicine, Detroit, Mich. Introduced by J. N. Etteldorf

186. Atypical neonatal thyrotoxicosis Ralph Cash ~ and Karl Stillwater,"x" Sinai Hospital of Detroit, Mich. Introduced by Charles F. Whitten

187. Intrauterine growth and growth hormone Marvin Cornblath, Willard J. Blankenship, ~ Guy Joassin, "x" Mary L. Parker, ~" and Kenneth R. Swiatek,~" University of Illinois College of Medicine, Chicago, Ii1., Vanderbilt University School of Medicine, Nashville, Tenn., and Washington University School of Medicine, St. Louis, Mo.

188. Diurnal plasma cortisol variation in prematures, infants, and children Robert C. Franksff Vanderbilt University School of Medicine, Nashville, Tenn. Introduced by M. T. Stahlman

November 1966

189. The serum growth hormone response to hypoglycemia in dwarfism S. Douglas Frasier, "x" University of California School of Medicine, Los Angeles, Calif. Introduced by Robert A. Ulstrom

190. Diazoxide as an inhibitor of pancreatic insulin release Orville C. Green, "x"Northwestern University, Chicago, Ill. Introduced by R. B. Lawson

191. Direct spectrophotometric quantitation of thin-film steroid chromatograms Bette L. Hamman ~'- and Malcohn M. Martin, "~ Georgetown University School of Medicine, Washington, D. C. Introduced by Philip L. Calcagno

192. The measurement of plasma cortisol--a micromethod utilizing the steroid-binding capacity of plasma Donald A. Hillman, Siegfried M. Pueschelff and Beverley E. Murphy, ~" Montreal Children's Hospital and McGill University, Montreal, Canada

193. Adrenal function in periodic

f ever Eugene C. Jarrettf" Gerald H. Holman, "x" and Virendra B. Mahesh, ~ Medical College of Georgia, Augusta, Ga. Introduced by ~Villiam B. Cleveland

194. Low cortisol secretion rate in neonatal hypoglycemia Frederic Kennyff Chawalit Preeyasombat, ~ and Catherine Richardsff University of Pittsburgh School of Medicine, Pittsburgh, Pa. Introduced by Paul Taylor

195. Pre- and postoperative studies of pituitary function in cranio p haryn gioma

Volume 69 Number 5 part 2

Frederic Kenny, e Anthony Susen, ~ Nenita Iturzaeta, ~ and Ali Askari, ~ University of Pittsburgh School of Medicine, Pittsburgh, Pa. Introduced by Donald Medearis, Jr.

196. Diurnal rhythmicity of corticosteroid secretion in the newborn Harvey D. Klevit, ~ University of Oregon Medical School, Portland, Ore. Introduced by Melvin M. Grumbach

197. Insulin and growth hormone response in a diabetic progeny with hypoglycemia James A. Monteleone, ~ Marvin A. Cook, ~ Charles P. Sheehan, ~ Ralph Kinsella, Jr.,'* and Thomas F. Frawley, ~ St. Louis University School of Medicine and Cardinal Glennon Memorial Hospital, St. Louis, Mo. Introduced by Arthur E. McElfresh

198. Liver protein and ribonucleic acid synthesis rates in stunted braln-injured rats H. David Mosier and Judy Y. Duh, Illinois State Pediatric Institute and the University of Illinois College of Medicine, Chicago, Ill.

199. Excretion of human growth hormone in the urine of normal adults and children Samir S. Najjar "~ and Robert M. Blizzard, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Md.

200. Plasma testosterone in normal and virillzed children Maria New,~ David Gundy, ~ Rachel Theodor, ~ and Ralph E. Peterson, "x" The New York Hospital-Cornell Medical Center, New york, NI Y. Introduced by Wallace W. McCrory

Abstracts read by title 9 9 7

20I. Studies of diazoxide on carbohydrate metabolism in the rat Siegfried M. Pueschel, ~ Eleanor Colle, and Donald A. Hillman, Montreal Children's Hospital and McGill University, Montreal, Canada

202. Plasma growth hormone in patients with Klinefelter's ( X X Y Y ) and Down's (trisomy 21) syndromes Allen W. Root, "x" William J. Mellman, Alfred M. Bongiovanni, and Walter R. Eberlein, University of Pennsylvania School of Medicine and Children's Hospital of Philadelphia, Pa.

203. Sexual differentiation of the gonaducts during maturation of 3P-ol-dehydrogenase in the gonads, adrenal cortex, and placenta of fetal rats Robert J. Schlegel, "x"Elvira Farias, ~ Nicholas Russo, "x" John R. Moore, ~ and Lytt I. Gardner, State University of New York, Upstate Medical Center at Syracuse, Syracuse, N. Y.

204. Genetic and clinical aspects of the syndrome of chronic moniliasis and endocrine deficits Daniel C. Shannon, ~ Gordon Johnson, ~ and K. Frank Austen, ~ Harvard Medical School, Boston, Mass. Introduced by John D. Crawford

205. Sex hormone production in childhood as evaluated by cytologic study of urinary sediment Henry K. Silver, University of Colorado School of Medicine, Denver, Colo.

206. The response of children with hypoparathyroidism to long-term intermittent vitamin D, therapy Myron Siner ~ and John F. Crigler, Jr., Harvard Medical School, Boston, Mass.

99 8 Society [or Pediatric Research

207. The role of autoimmune thyroid#is in the etiology of juvenile nongoitrous myxedema J. D. Smith, C. R. Caqas,* and J. M. Montalvo,* Children's Memorial Hospital, and Clinical Research Center, University of Oklahoma Medical Center, Oklahoma City, Okla., and Department of Pediatrics, University of Mississippi Medical Center, Jackson, Miss.

208. Compensatory growth in tissue culture Edna H. Sobel,* Albert Einstein College of Medicine, New York, N. Y.

GENETICS

209. Modified silver stain for visualization of nuclear material in m a n

Mihaly Bartalos* and Luz Carlota Reves,~ Department of Pediatrics, Howard University College of Medicine, Washington, D.C. Introduced by Roland B. Scott

210. Autoradiographic analysis of the specific D chromosome bearing the haptoglobin locus Gerald E. Bloom,* Park S. Gerald, and Louis K. Diamond, Harvard Medical School, Boston, Mass.

211. A proposed classification of mosaicism in man Margaret J. Corny,* Department of Paediatrics, University of British Columbia, Vancouver, British Columbia, Canada Introduced by Sydney Segal

212. Etiology of nondls]unction: Lack

of evidence for genetic control Richard C. Juberg* and Louise M. Davis,* University of Michigan, Ann Arbor, Mich., and Elkhart County Public Health Unit, Elkhart, Ind. Introduced by Albert V. Hennessy

November 1966

213. Familial intrahepatic cholestasls with mental and growth retardation Richard C. Juberg,* Roxie M. HollandMoritz,* Keith S. Henley,* and Carlos F. Gonzalez,* University of Michigan, Ann Arbor, Mich., and St. Clair, Mich. Introduced by Albert V. Hennessy

214. Tetraploid-diploid mosaicism in a surviving infant G. Kohn, * W. Mellman, J. Loftus,* and F. Oski, Department of Pediatrics, University of Pennsylvania School of Medicine, and Children's Hospital of Philadelphia, Philadelphia, Pa.

215. Dermatoglyphic studies in cleft lip and palate Stella B. Kontras* and Joann G. Bodenbender,* Department of Pediatrics, College of Medicine, Ohio State University, Columbus, Ohio Introduced by Bruce D. Graham

216. Hypospadias and other

anomalies associated with partial deletion of short arms of chromosome No. 4 Jos~ Carnelro Le~o, ~ Richard L. Neu, ~ and Lytt I. Gardner, State University of New York, Upstate Medical Center at Syracuse, Syracuse, N. Y.

217. Trisomy 21/trisomy I8 mosaicism in a boy with apparent Down's syndrome James F. Marks* and Billie J. Spector,* Department of Pediatrics, The University of Texas Southwestern Medical School, Dallas, Texas Introduced by Chester W. Fink

218. Probable tetrasomy 21 in an infant with multiple congenital anomalies

Volume 69 Number 5 part 2

Patricia L. Monteleone,"x" St. Louis University School of Medicine and Cardinal Glennon Memorial Hospital, St. Louis, Mo. Introduced by Arthur E. McElfresh

219. Enzymes in cultivated human fibroblasts derived from trisomic Down's syndrome Henry L. Nadler, ~ Parvin Justice, ~ Tohru Inouye, ~ and David Yi-Yung Hsia, Northwestern University Medical School, Chicago, Ill.

220. Variable etiology of Hirschsprung's disease: Evidence of genic and chromosomal factors Eberhard Passarge, ~ Children's Hospital Research Foundation, University of Cincinnati, Cincinnati, Ohio Introduced by Josef Warkany

221. Phenotypes of diploid vs. nondiploid human cells in vulture Jean H. Priest "~ and Jane L. Showacref" University of Colorado School of Medicine, Denver, Colo. Introduced by C. Henry Kempe

222. Studies in a child with partial monosomy of the 22 chromosome Leonard E. Reisman, ~" Bryan Hall, ~ and John W. Murphy, ~ University of Louisville School of Medicine, Louisville, Ky.

223. Local chromosomal mosaicism: Cytogenetic studies of cell cultures derived from cleft palate explants Leonard E. Reisman~ and John W. Murphy, ~ University of Louisville School of Medicine, Louisville, Ky. Introduced by Frank Falkner

224. Rib-gap defect: Relevance to normal rib development David W. Smith, Karl Theiler, ~ and G. Sehachenmann,"x" University of Ziirich,

Abstracts read by title 9 9 9

Ziirich, Switzerland, and University of Wisconsin Medical School, Madison, Wis.

225. Determination of carrier state in cystic fibrosis by quadratic discriminatory analysis of sweat chloride concentration tests Ann Sproul"~" and Nancy N. Huang, ~ St. Christopher's Hospital for Children and Temple University School of Medicine, Philadelphia, Pa., and the University of California-San Francisco Medical Center, San Francisco, Calif. Introduced by Victor C. Vaughan, III

226. Dermatoglyphics and congenital heart disease E. Franklin Stone, Jr., ~ Richard A. Kronmal, r and Donald H. Mott, r University of Washington School of Medicine, Seattle, Wash. Introduced by Robert W. Deisher

227. The perpetuation of hemophilia by mutation Herbert S. Strauss, ~" Children's Hospital Medical Center and Harvard Medical School, Boston, Mass. Introduced by Louis K. Diamond

228. An abnormal acrocentric chromosome in a girl with chronic granulocytic leukemia and in her immediate relatives J. M. Teasdale, ~" J. R. Bensimon, "x"and J. R. Miller,~ Department of Paediatrics, University of British Columbia, Vancouver, British Columbia, Canada Introduced by Sydney Segal

229. DI trisomy-!ike malformations in a patient partially monosomic for the D~ chromosome Wladimir Wertelecki,~" Park S. Gerald, and Louis K. Diamond, Harvard Medical School, Boston, Mass.

1 0 O0 Society /or Pediatric Research

HEMATOLOGY

230. Platelet function in the newborn: In vivo study o/ adhesiveness Bruce D. Ackerman,* University of California-California College of Medicine, Los Angeles, Calif. Introduced by Thomas L. Nelson

231. Effect of steroids on Factor VIII level Virginia Canale, ~ Carl H. Smith, and Philip Lanzkowsky,"~ Cornetl University Medical Center, New York, N. Y.

232. Pyruvate kinase deficiency and blood group incompatibility in an Amish kindred Robert J. Clayton "~and Victor A. McKusick, ~ Department of Pediatrics, Georgetown University, Washington, D. C., and Department of Medicine, The Johns Hopkins Hospital, Baltimore, Md. Introduced by Philip L. Calcagno

233. Anemia and neutropenla in human copper deficiency Angel Cordano ~ and George G. Graham, British-American Hospital, Lima, Peru, and Baltimore City Hospitals, Baltimore, Md.

234. Hyperphagic obesity associated with central nervous system leukem?a Jean A. Cortner, ~ Department of Pediatrics, Roswell Park Memorial Institute, Buffalo, N. Y. Introduced by Mitchell I. Rubln

235. Platelet transfusions in pediatric hematology Isaac Djerassi, The Children's Hospital of Philadelphia, Philadelphia, Pa.

236. Antibody studies in human leukemia Inta J. Ertel, "x"Cora Bullis, "~ and William

November 1966 H. Murphy, "x" University of Michigan, Ann Arbor, Mich. Introduced by James L. Wilson

237. The effect oJ heine and protoporphyrin on amlnolevulinic acid synthetase activity Felix Feldman, ~ Richard D. Levere, ~ and Herbert C. Lichtman, ~ Maimonides Hospital and State University of New York, Brooklyn, N. Y. Introduced by Howard A. Joos

238. A rapid procedure for determining the osmotic fragility of erythrocytes B. J. Fogel,"x" C. E. Shields, r L. B. Altstatt, "z and T. E. Allen, "~ Walter Reed Army Institute of Research, Washington, D.C. Introduced by W. L. Nyhan

239. Chromosomal defects in human lymphocytes following BCNU therapy Kay Harrod, "x" Jean A. Cortner "x" and Avery A. Sandberg, r Roswell Park Memorial Institute, and State University of New York at Buffalo, Buffalo, N. Y. Introduced by Mitchell I. Rubin

240. Serum thrombotic accelerator deficiency in the newborn W. E. Hathaway "x" and Barbara J. Henderson, "x"University of Colorado Medical Center, Denver, Colo. Introduced by John H. Githens

241. The autohemolysis test and ABO incompatibility W. E. Hathaway,* B. J. Henderson, ~ and Vinai Suvatte, ~ University of Colorado Medical Center and Children's Hospital, Denver, Colo. Introduced by L. Joseph Butterfield

242. In vivo effects of contrast media on the coagulation mechanism

Volume 69 Number 5 part 2

Margaret Hilgartner, ~ Cornell University Medical Center, New York, N. Y. Introduced by Carl H. Smith

243. Effect of heparinlzed versus citrated blood on nonesterified fatty acid levels during exchange transfusion William Krivit and Virginia Betlaeh,a University of Minnesota Medical School, Minneapolis, Minn.

244. Effect of prednisone and 6-mercaptopurine on the proliferative capacity of leukemic cells of children with acute lymphatic leukemia Beatrice C. Lampkin~" and Alvin M. Mauer, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio

245. Rapid determination of serum albumin binding capacity by gel filtration as a criterion for exchange transfusion David C. Law '~ and Louis Gluck, Yale

University School Haven, Conn.

of

Medicine, New

246. Erythrocyte protoporphyriau comparisons of photohemolysis, intracellular porphyrin distribution, and fluorescence Harold W. Lischner~ and Alice B. Brody,~ St. Christopher's Hospital for Children and Temple University School of Medicine, Philadelphia, Pa.

247. Hereditary stomatocytosls: A disease or a syndrome? Bertram Lubin, ~ Frank Oski, David Nathan, ~ and Arthur Schneider, e Children's Hospital of Philadelphia and University of Pennsy!vania School of Medicine, Philadelphia, Pa., Harvard Medical School,

Abstracts read by title 1 0 0 1 Boston, Mass., and University of California School of Medicine, San Francisco, Calif.

248. Evidence of hypercoagulability in premature infants with the respiratory disease syndrome Marguerite Markarian, "~ Jaequeline J. Jackson, ~ Anne Bannon, x" and Eliana Rosenbliit,~ University of Colorado Medical Center, Denver, Colo., and University of Chile, Santiago, Chile Introduced by John H. Githens

249. A clinical trial of heparin therapy in premature infants with and without the respiratory distress syndrome M. Markarian, "~ J. Jackson, ~ A. Bannon,"~

E. Rosenblfit, ~ R. Martorell, "~ L. O. Lubehenco, and J. H. Githens, University of Colorado Medical Center, Denver, Colo., and University of Chile, Santiago, Chile

250. Hereditary spherocytosis: The metabolism of erythrocytes trapped in the spleen D. M a y m a n , ~ M. R o w l a n d , ~ L. G. Israels, "~ and A. Zipursky, Department of

Pediatrics and Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

251. Blockage by actinomycin D of sterold-mediated increases of leukocyte alkaline phosphatase activity Ernest E. McCoy, John Karpel, ~ and Teresa Viettl, e Department of Pediatrics, University of Missouri, Columbia, Mo., and Washington University, St. Louis, Mo.

252. Metabolic characteristics of iron-deficient red cells Lorna G. Macdougall,~ The Johns Hopkins University School of Medicine, Baltimore, Md. Introduced by William H. Zinkham

1 O0 2 Society for Pediatric Research

November 1966

253, Assay o/plasma Factor VIH activity in capillary blood samples

vania and University of Pennsylvania School of Medicine, Philadelphia, Pa.

Campbell W. McMillan, ~" North Carolina University School of Medicine, Chapel Hill, N. C. Introduced by Floyd W. Denny, Jr.

254. Childhood Hodgkin's disease mortality: An etiologic clue Robert W. Miller, National Cancer Institute, National Institutes of Health, Bethesda, Md.

255. Electronic measurements of cell volume in acute leukemia Fereydoun Mochir-Fatemi "~ and Sanford L. Leikin, Children's Hospital of the District of Columbia, Washington, D. C. 256. The fallacy oJ the fat

iron-deficient child J. Lawrence Naiman, e Frank A. Oski,

and Janifer M. Judiseh, e Department of Pediatrics, Hospital of the University of Pennsylvania and University of Pennsyl* vania School of Medicine, Philadelphia, Pa.

257. Hydrops [etalis and erythroblastosis in homozygous alpha thalassemia David G. Nathan, ~ Park S. Gerald, Shirley Driscoll, r and John M. Craig, r Harvard Medical School, Boston, Mass.

258. Hemoglobin synthesis in megalob!astosis Thomas F. Necheles, ~ Richard Sheehan, ~ and Donald M. Allen,* Tufts-New England Medical Center, Boston, Mass. Introduced by Sydney S. Gellis

259. The pentose phosphate pathway in the erythrocytes of the premature infant Frank A. Oski, Department of Pediatrics, Hospital of the University of Pennsyl-

260. Measurement of in vivo elution of Cr5' from fetal red blood cells and estimation of their true survival Howard A. Pearson, University Of Florida, College of Medicine, Gainesville, Fla.

261. HypoDlastic bone marrow in anorexia nervosa Howard A. Pearson and Ward D. Noyes,~ University of Florida College of Medicine, Gainesville, Fla.

262. Leukocyte kinetics in the newborn infant Roderic H. Phibbs, "~ University of California-San Francisco Medical Center, San Francisco, Calif. Introduced by William H. Tooley 263. Erpthrocytic glucose-6-phosphate

dehydrogenase isozymes of normal and deficient human subjects Patrick V. C. Pinto, ~ William A. Newton,

Jr., and Keith E. Richardson, ~ Departments of Physiological Chemistry and Pathology, The Ohio State University, Columbus, Ohio

264. Severe iron deficiency anemia in infants: The effects of transfusion on the blood volume and central venous pressure Darleen R. Powars ~ and Lillian Phang, "~ University of Southern California School of Medicine, Los Angeles, Calif. Introduced by John A. James

265. Cyclic neutropenia with azotemia and hyperuricemia Jean D. Ross* and Darryl C. DeVivo, "~ Harvard Medical School, Boston, Mass. Introduced by John D. Crawford 266. Variation of proliferative activity in leukemic cell populations

Volume 69 Number 5 part 2

E. F. Saunders ~ and A. M. Mauer, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio

267. Hemolysis associated with "fibro-AHF ''l therapy of hemophilia. A discussion of the mechanism and its possible prophylaxis J. B. Schorr, ~ S. Ballard, ~ and E. Radel, a Division of Pediatrics, Montefiore Hospital and Medical Center, and Department of Pediatrics, Albert Einstein College of Medicine, New York, N. Y. Introduced by Laurence Finberg

268. Alteration in the pattern of hemoglobin synthesis associated with rapid red cell production A. M. Shojania,~ Department of Pediatrics, University of Manitoba and St. Boniface General Hospital, Winnipeg, Manitoba, Canada Introduced by A. Zipursky

269. Histochemical and ultrastructural study of the liver in acute iron poisoning Camillus L. Witzleben~ and Nigel J. Chaffey,~ Children's Hospital Medical Center, Oakland, Calif., and Washington University Medical School, St. Louis, Mo. Introduced by Malcolm A. Holliday

270. Defective myeloid proliferation and differentiation in two patients with congenital neutropenia Karin Wriedt, ~ Emanuel Kauder, ~ and Alvin M. Mauer, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio MICROBIOLOGY, IMMUNOLOGY

271. Spontaneous and antigen-induced immunoglobulin

Abstracts read by title 1 0 0 3 heavy-chain synthesis in the tissues of the newborn rabbit W. Adler~" and R. T. Smith, University of Florida College of Medicine, Gainesville, Fla.

Immunofluorescent studies o/ IgG, IgA, and IgM antibodies in human rubella infection

272.

Joseph V. Baublis,* University of Michigan, Ann Arbor, Mich. Introduced by Richard J. Allen

Studies of viral serologic cross reactions

273.

Joseph A. Bellanti, ~ Sudie B. Russ, ~ George E. Holmes, ~" Wilbur H. Burnette, ~ and Edward L. Buescher, ~ Georgetown University School of Medicine and Walter Reed Army Institute of Research, Washington, D. C. Introduced by Philip L. Calcagno

274. Determination of the structure o/ the polioantibody globulins in the urine Ruth Berger, ~ Eugene Ainbender, ~ Magda M. Hevizy,"x" Helen D. Zepp, a and Horace L. Hodes, Mount Sinai Hospital, New York, N. Y.

275. Hereditary alterations in the specific immune response Rebecca H. Buckley~ and James B. Sialbury, Jr., Duke University Medical Center, Durham, N. C. 276. A clinical, epidemiologlc, virologic, and serologic search for perlnatal infection James D. CherrY,r Federico Soriano, "x" and Charles L Jahn, ~ Department of Pediatrics, University of Wisconsin School of Medicine, Madison, Wis. Introduced by Charles C. Lobeck

1 0 0 4 Society [or Pediatric Research

November 1966

Reduced rate of virus replication as observed by electron microscopy

Henry Gewurz,* Richard J. Pickering,* James Gordon,* Paul R. Wernick,* and Robert A. Good, Variety Club Heart Hospital, Minneapolis, Minn., and National Institute of Dental Research, National Institutes of Health, Bethesda, Md.

277.

L. A. Chitwood,* Department of Pediatrics, Children's Memorial Hospital, University of Oklahoma Medical Center, Oklahoma City, Okla. Introduced by Harris D. Riley, Jr.

278. In vitro studies of the lymphoma associated with the Chediak-Higashi syndrome Peter B. Dent,* Lloyd Fish,* James G. White, and Robert A. Good, University of Minnesota Medical School, Department of Pediatrics, Minneapolis, Minn.

279. Bacterial interference in the treatment of recurrent staphylococcal infections in a family Richard N. Fine,* Jean M. Onslow,* Mary L. Erwin,* and Jay O. Cohen,* Childrens Hospital of Los Angeles, Department of Pediatrics University of Southern California School of Medicine, Los Angeles, Calif., and Contagious Disease Hospital, Atlanta, Ga. Introduced by Robert M. McAllister

280. Cortisone-induced progressive vaccinia in the rabbit Vincent A. Fulginiti* and Gary Clark, ~ University of Colorado, Denver, Colo. Introduced by C. Henry Kempe

281. Thymic alymphoplasia with normal immunoglobulins: A new immunologic disease V. A. Fulginiti,* W. E. Hathaway,* D. S. Pearlman,* W. C. Reiquam, ~ H. N. Claman,* W. R. Blackburn,* J. H. Githens, and C. H. Kempe, University of Colorado Medical Center, Denver, Colo.

282. Effects of anti-inflammatory and cytotoxic agents on the complement (C') system

283. Interferon and human cytomegalovirus in vivo and in vitro L. A. Glasgow~ and J. B. Hanshaw, University of Rochester School of Medicine, Rochester, N. Y.

284. Lymphopenlc antibody deficiency syndrome, lymphoproliferative disease, and multiple allergies. Hyper-~A-, normal ~M" hyp~ and A-~D-globulinemia. A possible new congenital disorder A. S. Goldman,* M. E. Haggard,* J. W. McFadden, ~ S. E. Ritzmann,* E. W. Houston,* and R. L. Bratcher,* University of Texas Medical Branch, Galveston, Texas Introduced by C. W. Daeschner

285. Serologic response in shigellosis determined by a microtiter hemagglutination technique Kenneth C. Haltalin,* Betty M. Matteck,* and John D. Nelson,* University of Texas Southwestern Medical School, Dallas, Texas Introdueed by Heinz F. Eichenwald

Immunoglobulin disorder associated with congenital rubella 286.

Carolyn C. Huntley, Millie P. Hancock,* and John L. Sever,* Bowman Gray School of Medicine, Winston-Salem, N. C., and National Institutes of Health, Bethesda, Md.

287. Antigens for the detection of antichloramphenlcol antibody

Volume 69 Number 5 part 2

Robert N. Hamburger, University of California, San Diego School of Medicine, San Diego, Calif.

288. Vaccination of infants with influenza hemagglutinin vaccine Albert V. Hennessy and Fred M. Davenport, ~ University of Michigan School of Public Health, Ann Arbor, Mich.

289. Direct hemagglutination by Mycoplasma pneumoniae and its specific inhibition by immune serum T. Jacob John, ~ Marlene Stahl, "~ and Vincent A. Fulginiti, ~* University of Colorado School of Medicine, Denver, Colo. Introduced by C. Henry Kempe

290. Antinuclear factor in the childhood rheumatic diseases Helen Kass"~ and Virgil Hanson, e University of Southern California School of Medicine, and Childrens Hospital of Los Angeles, Los Angeles, Calif. Introduced by George Donnell

291. Response of children with kwashiorkor to viral infection Michael Katz, r Roy E. Brown, ~x" and Stanley A. Plotkin, Wistar Institute, Philadelphia, Pa., and Makerere Medical School, Uganda

292. Blastic transformation of lymphocytes oJ neonates Sanford L. Leikin and Fereydoun MochirFatemi, e Children's Hospital of the District of Columbia, Washington, D. C.

293. The incompetent lymphocytes o] the congenitally athymic state Harold W. Lischner, e Hope H. Punnett, ~" Catherine Dacou, ~ and Angelo M. DiGeorge, St. Christopher's Hospital for Children and Temple University School of Medicine, Philadelphia, Pa.

Abstracts read by title 1 0 0 5

294. Chronic noncongenital unexplained hypogammaglobulinemia, a new type of immunologic deficiency M. Menking,~ J. F. Taylor, r and W. A. Newton, Jr., Department of Pediatrics, Ohio State University, and The Children's Hospital, Columbus, Ohio

295. Morphologic and physiologic observations of cell function in athymic alymphocytosis ('~Swiss agammaglobulinemia") Michael E. Miller, ~ Department of Pediatrics and Immunology, Children's Hospital of Philadelphia, Philadelphia, Pa. Introduced by Klaus Hummeler

296. Characteristics of phytohemagglutln stimulation of guinea pig and rabbit spleen cells John R. Montgomery,~" and Robert R. Carpenter, ~ Departments of Pediatrics and Medicine, Baylor University College of Medicine, Houston, Texas Introduced by M. D. Yow

Evaluation oJ a measles skin test antigen 297.

John D. Nelson, "~ George Sandusky,~ and F. Bruce Peck, Jr., e* University of Texas Southwestern Medical School, Dallas, Texas, and Lilly Laboratory for Clinical Research, Indianapolis, Ind. Introduced by Heinz F. Eichenwald

298. Hepatic coma due t o isoniazid and serum glutamic oxalacetic transaminase activity in children with tuberculosis D. O'Hare, ~ F. iVaziri,~ and R. Toledo, ~ New York University School of Medicine, New York, N. Y. Introduced by R. L. Nemir

1 O0 6 Society [or Pediatric Research 299. The importance of complement in the nonspecific inflammatory

response Arthur R. Page, Henry Gewurz,* and Richard J. Pickering,* University of Minnesota Medical School, Department of Pediatrics, Minneapolis, Minn.

300. Studies of rubella syndrome and infection with living rubella virus Stanley A. Plotkin, Michael Katz, ~ and T. H. Ingalls,* Wistar and Phipps Institutes, Philadelphia, Pa.

301. Lymphoid hypoplasia, hypergammaglobulinemia, antibody deficiency, autoimmune hemolytic anemia, and nephritis in an infant with a familial immune defect Jane Schaller, ~ Starkey D. Davis, "~ YiChuan Ching, ~ David Lagunoff,* Christopher P. Williams, ~ and Ralph J. Wedgwood, Departments of Pediatrics and Pathology, University of Washington, Seattle, Wash.

302. Immunoglobulin deficiency in Bloom's dwarfism Edgar J. Schoene and Martin A. Shearn,'* Kaiser Foundation Hospital, Oakland, Calif. Introduced by Malcolm A. Holliday

303. Amantadine therapy in a case of dysgammaglobullnemia type 2 and enteropathy associated with congenital rubella William Schubert, Gilbert Schiff,~ and Clark West, Departments of Pediatrics, Medicine, and Microbiology, University of Cincinnati, Cincinnati, Ohio

304. Special role of the spleen in clearance of pneumococci Martin L. Schulkind~ and Elliot F. Ellis,~

November 1966

University of Florida, College of Medicine, Gainesville, Fla. Introduced by Richard T. Smith

305. A rapid screening test for detecting congenital rubella John L. Sever, ~ Robert J. Huebner, ~ and Gilles R. Monif,"~ National Institutes of Health, Bethesda, Md. Introduced by Robert M. Chanock

306. The effect of antibiotics on Mycoplasma pneumoniae (Eaton's agent) Robert I. Slotkin, e Wallace A. Clyde, Jr., and Floyd W. Denny, University of North Carolina School of Medicine, Chapel Hill, N.C.

307. Lymphocyte studies in children with tuberculosis Elizabeth M. Smithwick,e State University of New York, Downstate Medical Center, Brooklyn, N. Y. Introduced by R. Janet Watson

308. Bacterial inhibitors in normal

flora Katherine Sprunt, Winifred Redman,* and Charlotte Reischauer,~ Columbia University, New York, N. Y.

309. Detection of in utero infection by cord blood immune globulin analysis E. Richard Stiehm, ~" James D. Cherry,* and Arthur J. Ammann,* University of Wisconsin, Madison, Wis., and University of California School of Medicine, San Francisco, Calif. Introduced by C. C. Lobeck

310. Booster responses to diphtheria and tetanus toxoids in infants on different basic schedules of immunization Jeanette

Wilkins, *

Bernard

Portnoy, *

Volume 69 Number 5 part 2

John M. Leedom,* Daniel Ivler,* Allen W. Mathies, Jr., and Paul F. Wehrle, University of Southern California School of Medicine and Children's Division, Los Angeles County General Hospital, Los Angeles, Calif.

3.11. Human cytomegalovirus: Cinematography of intracellular lesion development Harry T. Wright, Jr., Frederick H. Kasten,* and Robert M. McMlister, University of Southern California School of Medicine, Childrens Hospital of Los Angeles, and Pasadena Foundation for Medical Research, Los Angeles, Calif. NEPHROLOGY

312. Gestational and postnatal development of renal capacity for acid excretion A. C. Allen* and R. H. Usher, MeGill University, Montreal, Canada

313. The isolation and quantitation of a previously undescribed urinary pigment (M532) in normal humans R. K. Baker, "z E. Orti, "x" and J. T. Lanman,* Department of Pediatrics, Downstate Medical Center, Brooklyn, N. Y. Introduced by R. J. Watson

314. Glomerular filtration rate: Factors influencing its measurement by means of endogenous creatinine clearance. Warren F. Dodge and Luther B. Travis,* Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas

315. Fanconi syndrome with alkalosls Chester M. Edelmann, J r , Hayim Boichis, * and Ian B. Houston,* Department of Pediatrics, Albert Einstein College of Medicine, New York, N. Y.

Abstracts read by title 1 0 0 7 316. Evaluation of the role of urethral meatal stenosis in the pathogenesis of urinary tract infection in the female child Patricia A. Forbes, "z Bernadette Nogrady, r J. Scott Dunbar, r and Keith N. Drummond, Montreal Children's Hospital, Montreal, Canada

317, Hemolytic-uremic syndrome in two siblings Wolfgang W. Hagge, r Edmund C. Bruke, ~ Keith E. Holley,~ and Gunnar B. Stickler, Mayo Clinic and Mayo Graduate School, Rochester, Minn.

318. Iuvenile nephronophthisis, a familial disease Wolfgang W. Hagge,* Keith E. Holley,* Edmund C. Burke,* and Gunnar B. Stickler, Mayo Clinic and Mayo Foundation, Rochester, Minn.

319. Light chains in human renal disease Roger C. Herdman,* Richard Hong,* Alfred F. Michael, and Robert A. Good, University of Minnesota Medical School, Department of Pediatrics, Minneapolis, Minn.

320. Relationship of serum betalo-globulin levels to renal disease in nephrotoxic nephritis of rats Nancy H. Holland, Department of Pediatrics, University of Kentucky Medical Center, Lexington, Ky.

321. Unique specificity of mouse angiotensinogen to heterologous renins William J. University Mich., and Introduced

Oliver* and Franz Gross,* of Michigan, Ann Arbor, Basle, Switzerland by Albert V. Hennessy

322. Pathogenesis o[ cystic disease of

the kidney

1 008

Society [or Pediatric Research

Mohamed Safouh* and Robert L. Vernier, University of California, Los Angeles, Calif.

323. Fifteen year experience with steroid therapy of the nephrotic syndrome Alina Serdakowska, r Edward Wasserman, "~ Lawrence B. Slobody,':" and Kurt Lange, ~" Renal Service, Departments of Medicine and Pediatrics, New York Medical College, New York, N. Y. Introduced by Miriam Lending

324. Effect of aortographic contrast media on renal function and histology Luther B. Travis, ~" Kenneth Dorman, "z Warren F. Dodge, and Manuchehr Assemi,~" Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas

325. Immunosuppressive therapy of diffuse renal disease Robert Vernier, Fred G. Smith, Jr., Birger Tinglof, e Alfred Michael, Keith Drummond, Roger Herdman, ~" John Levitt, ~ and Robert Good, University of California, Los Angeles, Calif., and University of Minnesota, Minneapolis, Minn.

326. Immunosuppressive threapy o[ patients with specific renal disease John F. Wilson, University of Utah College of Medicine, Salt Lake City, Utah

327. The nature of the renal lesion in Lowe's syndrome Camillus L. Witzleben,*" Edgar J. Schoen, ~ and Wuhao Tu,** Children's Hospital Medical Center, and Kaiser Foundation Hospital, Oakland, Calif. Introduced by Malcolm A. Holliday

328. Metabolic loci of aminonucleoside effect in kidneys of prenephrotic rats Takashi Yoshida ~ and Jack Metcoff, Michael Reese Hospital and Medical

November 1966 Center, and Chicago, Ill.

Chicago Medical School,

329. Nephropathy due to congenital syphilis in a lO-week-old infant A. M. Yuceoglu, ~ J. Churg, r Y. Mallika, ~ and P. Pollner, ~ Downstate Medical Center, Brooklyn, N. Y., and Mt. Sinai Hospital, New York, N. Y. Introduced by R. J. Watson

NEUROLOGY

330. Electromyographic and histopathologic correlations in arthrogryposis Lawrence D. Amick, ~ Warren W. Johnson, ~ and Harris L. Smith, "x" St. Jude Children's Research Hospital and University of Tennessee, Memphis, Tenn. Introduced by Donald Pinkel

331. Myelin formation in phenylketonuria H. Peter Chase ~" and Donough O'Brien, University of Colorado Medical Center, Denver , Colo.

332. Neurologic maturity and dysJunction as assessed by "overflow" testing Herbert J. Cohen, ~ Lawrence T. Taft, ~ Maddur S. Mahadeviah, ~ and Herbert G. Birch, ~ Albert Einstein College of Medicine, New York, N. Y. Introduced by Henry L. Barnett

333, Nemaline myopathy: A histochemical study Victor Dubowitz, ~ Institute for Muscle Disease and Department of Pediatrics, Cornell University Medical College, New York, N. Y. Introduced by Wallace W. Mcerory

334. Prenatal and postnatal developmental consequences of maternal phenylketonuria

Volume 69 Number 5 part 2

Robert O. Fisch, ~ William A. Walker, "x"

and John A. Anderson, University of Minnesota Department of Pediatrics, Minneapolis, Minn.

335. Cerebral dysfunction in adopted children Richard C. Gilmartin ~ and Marshall D.

Schechter, "~ Department of Pediatrics, Children's Memorial Hospital, University of Oklahoma Medical Center, Oklahoma City, Okla. Introduced by Harris D. Riley, Jr.

336. Reduction of cerebral ventrlcular hypertension with 1,4:3,6 dianhydro-D-glucitol Patricia W. Hayden s and David B. Shurtleft,"~ University of Washington Medical School, Seattle, Wash. Introduced by Robert A. Aldrich

337. Metabolic factors in the pathogenesis of kernicterus Lois Johnson, Section on Newborn Pediatrics, Pennsylvania Hospital, and Department of Pediatrics, School of Medicine, University of Pennsylvania, Philadelphia, Pa.

338. Monoamlne oxidase activity of brain tissue in experimental puppies Miriam Lending and A. Louis Southren, ~ New York Medical College, New York, N.Y.

339. Hyperphenylalaninemla and tyrosinemia and ascorbic acid intake in prematures Irwin J. Light, "x" Helen K. Berry, ~ and

James M. Sutherland, University of Cincinnati, Cincinnati, Ohio

340. Caloric intake of low birth weight infants related to mental development L. O. Lubchenco and M. DelivoriaPapadopoulos,"x" Premature ~and Newborn

Abstracts read by title 1 0 0 9

Center, University of Colorado Medical Center, Denver, Colo.

341. Concerning the significance of maternal phenylketonuria C. Charlton Mabry, Joseph C. Denniston, "x"and James G. Coldwell, "• University of Kentucky Medical Center, Louisville, Ky., Pennsylvania State Health Department, Harrisburg, Pa., and Children's Medical Center, Tulsa, Okla.

342. A 25 year follow-up study on the hyperkinetlc child with minimal cerebral dysfunction Jane S. Rowe, ~ Miriam M. Menkes, "x"and John H. Menkes, The Johns Hopkins University School of Medicine, and Maryland Institute for Children, Baltimore, Md.

343. Alterations in serum proteins and lipoproteins in Niemann-Pick disease Larry Schneek,"~ Abraham Saifer,r and Bruno W. Volk, ~" Isaac Albert Research Institute of Jewish Chronic Disease Hospital, and the State University of New York, Downstate Medical Center, Brooklyn, N. Y. Introduced by Sumner Berkovich

344. Retarded electroencephalographic development in hypothyroid infants Marvin A. Schultz, ~ Franz J. Schulte,

and Arthur H. Parmelee, Department of Pediatrics, School of Medicine, University of California, Los Angeles, Calif.

345. Neurovisceral storage disease: Evidence for the accumulation of mucopolysaccharides within lysosomes C. Ronald Scott,"x"David Lagunoff,~" and Benjamin R.: Trump, ~ University of Washington, School of Medicine, Seattle, Wash. Introduced by Thomas K. Oliver, Jr.

1 0 1 0 Society for Pediatric Research 346. An approach /or studying the effects of early stimulation on the subsequent development of premature infants Norman Solkoff,~ Sumner J. Yaffe, and David Weintraub, '~ State University of New York at Buffalo, N. Y.

347. Maturational changes in bladder muscle Kenneth

F. Swaiman, ~" Francis S. Wright, ~ and William E. Bradley,~ University of Minnesota Medical School, Minneapolis, Minn. Introduced by William Krivit

348. Brain growth and protein synthesis in weanling rats /ed synthetic amino acid diets Georges van den Berghe~ and Irwin A. Schafer, Stanford University School of Medicine, Palo Alto, Calif.

349. A study of the auditory evoked response obtained during sleep from the scalp of the premature infant E. D. Weitzman, L. Duhamel, and L. Graziani, Saul R. Korey Department of Neurology and Department of Pediatrics, Albert Einstein College of Medicine, New York, N. Y. PHYSIOLOGY, METABOLISM

350. Histidinemia, further observations with direct demonstration o/ absent histidase activity in liver Victor H. Auerbach, Angelo M. DiGeorge, Gary C. Carpenter, ~ and Robert C. Baldridge,~ St. Christopher's Hospital for Children and Temple University School of Medicine, Philadelphia, Pa.

351. Mitotic index in ieiunal mucosa o/ rats subiected to /asting or proteln-deficient diets

November 1966

Oscar Brunser and Nelly Pak, Pediatrics Research Laboratory and Nutrition Research Center, School of Medicine, University of Chile, Santiago, Chile Introduced by Fernando Miinekeberg

352. Rhabdomyolysis after routine administration of succinylcholine in children Gary G. Carpenter, ~ Victor H. Auerbach, Angelo M. DiGeorge, Bernard W. Mayer, ~" and Henry S. Schutta, ~ St. Christopher's Hospital for Children and Pennsylvania Hospital, Philadelphia, Pa.

353. Familial hypophosphatemia with atypical osseus changes Patrick C. N. Clarke, "x"Warren F. Dodge, Luther B. Travis, "~ and E. Burke Evans, ~ University of Texas Medical Branch, Galveston, Texas

354. Juvenile osteoporosls: Quantitative microradiographic studies Mark D. Cloutier, "~ Alvin B. Hayles,~ B. Lawrence Riggs, ~ Jenifer Jowsey, r and William H. Bickel,~ Mayo Clinic and Mayo Foundation, Rochester, Minn. Introduced by Gunnar B. Stickier

355. Epinephrine response to tolbutamide Edward C. Defoe, Aytan Imamoglu, and Henry Sauls, University of Minnesota, Minneapolis, Minn. Introduced by John Reynolds

356. Hypermethioninemia: Symptom or syndrome? Victor Dubowitz, ~ Cedric C. Harvey, ~ C. Cusworth,~" and Charles E. Dent, r Department of Child Health, University of Sheffield, England, and Medical Unit, University College Hospital, London, England Introduced by Wallace W. MeCrory David

357. Hyperuricemia in glycogen storage disease

Volume 69 Number 5 part 2

Richard N. Fine, ~ Jose Strauss, and George N. Donnell, University of Southern California School of Medicine and Children's Hospital of Los Angeles, Los Angeles, Calif.

358. In vivo study of disaccharide hydrolysis and monosaccharide absorption in jejunum M. Genel ~" and G. M. Gray, ~ U. S. Army Tropical Research Medical Laboratory and San Juan City Hospital, San Juan, Puerto Rico Introduced by A. M. Bongiovanni

359. Bilirubin conjugation by activated preparations of glucuronyl transferase (S) Elias Halac ~ and Albert Reff, ~ New York University School of Medicine, New York, N.Y. Introduced by Joseph Dancis

360. Balance of Jatty acids in inJant nutrition Ray Hepner, Prasanna Nair, "~ M. Mujeeb, ~ and Sonia Ordonez, ~ University of Maryland, Baltimore, Md.

361. Electron microscopic examination oJ glycogen distribution in tissues of Pompe's disease George Hug, "~ William K. Schubert, and Gail Chuck, ~ The Children's Hospital Clinical Research Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio

362. Hepatic glycogen storage disease with a deject in the phosphorylase system George Hug, ~ William K. Schubert, and Gall Chuck, e The Children's Hospital Clinical Research Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio

363. Isomaltase deficiency without sucrase deficiency

Abstracts read by title 1 0 1 1

Carl Kind, ~ L-M. Young, e" J. May, ~ and R. Klein, Boston City Hospital, Boston, Mass.

364. Relationship oJ intramuscular electrolytes to membrane potential Carl Kind, ~ F. Cockburn, "x"and R. Klein, Boston City Hospital, Boston, Mass.

365. Intestinal lactase---an adaptive enzyme? Maurice D. Kogut, "~ George N. Donnell, and Kenneth N. F. Shaw, University of Southern California School of Medicine, and Childrens Hospital of Los Angeles, Los Angeles, Calif.

Comparison oJ rectosigmold motility in children with recurrent abdominal pain and ulcerative colitis 366.

Frederic B. Kopel, ~ Ih Chin Kim, ~ and Giulio J. Barbero, Children's Hospital of Philadelphia, Philadelphia, Pa.

367. Pharmacokinectics of salicylate elimination in infants and children Gerhard Levy~ and Sumner J. Yaffe, State University of New York at Buffalo, Buffalo, N. Y.

368. Submicro automation of a central clinical chemistry laboratory-development, experience, and evaluation C. Charlton Mabry, Robert E. Gevedon, "x" Irene E. Roeckel, ~ and Nathan Gochman, ~ University of Kentucky Medical Center and Technicon Research Laboratory, Louisville, Ky.

369. Correlation between weight increase and caloric intake in inJants with severe marasmic malnutrition Alejandr 0 Maccioni, ~ Fernando M6nckeberg, Gonzal0 Donoso, ~" and Iv(m Contreas, ~ Pediatric Reseraeh Laboratory, School of Medicine, University of Chile, Santiago, Chile

1 0 1 2 Society /or Pediatric Research 370. The feeding o[ normal infants with fish flour as sole source o[ protein Alejandro Maecioni,* Fernando MiJnekeberg, and Gonzalo Donoso, ~" Pediatric Research Laboratory, School of Medicine~ University of Chile~ Santiago, Chile

371. Salivary studies in cystic fibrosis Irwin D. Mandel, "~'Carolyn R. Denning, ~ Auslin H. Kutscher, ~ Robert H. Thompson, Jr., and Edward V. Zegarelli, "~ Columbia University, New York, N. Y. Introduced by Edward C. Curnen, Jr.

372. Iv4racellular pH changes in acute experimental salicylate intoxication John B. Moon, "~ University of Colorado Medical Center, Denver, Colo. Introduced by Don,ugh O'Brien

373. Citrullinemia with apparent impaired urea production Grant Morrow, "~ Lewis Barness, William Mellman, Lester Baker, ~ Mary Efron, and Robert Kaye, Clinical Research Center, Children's Hospital of Philadelphia, Department of Pediatrics, Hospital of the University of Pennsylvania and University of Pennsylvania School of Medicine, Philadelphia, Pa.

374. In vitro synthesis o[ sulfated "structural lipids" Guy M. McKhann and William Ho, ~ Stanford University School of Medicine, Pal. Alto, Calif.

375. A comparison o[ the subcellular distribution of bilirubin in liver and kidney Jiirgen c. Natzschka, ~ G. N. B. Storey, ~ and Gerard B. Odell, The Johns Hopkins University School of Medicine, Baltimore, Md,

November 1966 376. Relation o/ dietary intake of protein to concentration o/ urea nitrogen in serum of healthy infants C. E. Nelsen ~ and G. M. Owen, ~ University of Iowa, College of Medicine, Iowa City, Iowa

377. In vivo and in vitro studies of hepatic copper transport in normal humans and IVilson's disease (bepatolenticular degeneration) Peter Z. Neumann, ~ Mervin Silverberg, ~ and A. Daniel Rotenberg, ~" Montreal Children's Hospital, Montreal General Hospital, and McGill University, Montreal, Canada Introduced by Richard B. Goldbloom

378. A simple high sensitivity modification [or the column chromatography of amino acids Don,ugh O'Brien and Sanford L. Simons, "~ University of Colorado Medical Center, Denver, Colo.

379. Changes in the plasma levels o[ pyruvic, lactic, and alpha-ketoglutarlc acids during glucose-tolerance test in marasmic infants Sergio Oxrnan, Fernando Mfnckeherg, Alejandro Macciorli, ~" and Aristides Zfifiiga, Pediatric Research Laboratory, School of Medicine, University of Chile, Santiago, Chile

380. Studies on infant diarrhea. II. Absorption o[ glucose and net fluxes o[ water and salt in the jejunum Ram6n Torres-Pinedo, ~ University of Puerto Rico School of Medicine, San Jtlan, Puerto Rico Introduced by Philip R. Dodge

381. Effect o[ oral potassium on urinary salicylate excretion Berkeley L. Rich ~ and William T. Dob-

Volume 69 Number 5 part 2

bins,* Denver Children's Hospital, Denver, Colo. Introduced by L. Joseph Butterfield

382. Observations on the mode of action of penicillamine in cystinuria Andrew Sass-Kortsak, Silva P. Ficici,* Luc Paunier,* and Sanford H. Jackson,* Department of Paediatrics, University of Toronto, and Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada

383. Ketotic hypoglycemia: Quantitation of ketosis and liver glycogen during the ketogenic test diet Henry S. Sauls,* University of Minnesota Medical School, Minneapolis, Minn. Introduced by John W. Reynolds

384. Biochemical evidence for the persistence o] Hurler phenotype in cell culture Irwin A. Schafer, Julia C. Sullivan,* George Kofoed,* Jiri Svejcar,* and William van B. Robertson,* Stanford University School of Medicine, Palo Alto, Calif.

385. Hereditary tyrosinemia (tyrosinosis): pHPPA oxidase deficiency Charles R. Scriver, Jean Larochelle,* and Mervin Silverberg,* Montreal Children's Hospital, and l'H6tel Dieu, St. Valli~re, Qu6bec, Canada

386. Hyperammonemic ketosis in so-called idiopathic hyperglydnemia Juan Rodriguez Soriano,* L. S. Taitz,* Chester M. Edelmann, Jr., and L. Kauffman,* Division of Pediatrics, Montefiore Hospital and Medical Center, and Department Of Pediatrics, Albert Einstein College of Medicine, New York, N. Y.

Abstracts read by title 1 0 1 3 387. The use of THAM in the treatment of acidosis Jose Strauss, Richard N. Fine,* David A. Medina,* John Samson,* and George N. Donnell, University of Southern California School of Medicine, and Childrens Hospital of Los Angeles, Los Angeles, Calif.

388. Clinical, stable strontium kinetic. and urinary hydroxyprollne studies oJ infants with fatal hypophosphatasla Thomas M. Teree* and LeRoy Klein,* Department of Pediatrics and Surgery, Western Reserve University, Cleveland, Ohio Introduced by William M. Wallace

389. lntracellular pH in metabolic acidosis Virginia L. Tucker* and E. B. Brown,* University of Kansas School of Medicine, Kansas City, Kan. Introduced by Chien Liu

390. Studies on the late metabolic acidosis of the newborn Robert Usher and Alexander Allen,* MeGill University, Montreal, Canada

391. Relation between age, sex, rate of growth, and urinary excretion of endogenous hydroxyproline in normal infants M. K. Younoszai,* Dean W. Andersen,* L. J. Filer, Jr., and Samuel F. Fomon, University of Iowa College of Medicine, Iowa City, Iowa GENERAL

392. A feasibility study of patient sorting by a digital computer Herbert A. Haessler* and Gordon Nelson,* Science and Engineering Institute, Harvard Medical School and Massachu-

1 0 1 4 Society [or Pediatric Research

setts Institute of Technology, Boston, Mass. Introduced by John D. Crawford

393. Physical growth o[ the American Negro child

November 1966

Kannarkat P. Verghese, * Roland B. Scott, Gertrude Teixeira,* and Angella D. Ferguson, Department of Pediatrics, Howard University College of Medicine, Washington, D. C.