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ADHERENCE TO THE MEDITERRANEAN DIET IS ASSOCIATED WITH RENAL FUNCTION AMONG HEALTHY ADULTS: THE ATTICA STUDY
A57.E539 JACC March 9, 2010 Volume 55, issue 10A
HYPERTENSION, LIPIDS AND PREVENTION ADHERENCE TO THE MEDITERRANEAN DIET IS ASSOCIATED WITH RENAL FUNCTION AMONG HEALTHY ADULTS: THE ATTICA STUDY ACC Poster Contributions Georgia World Congress Center, Hall B5 Monday, March 15, 2010, 9:30 a.m.-10:30 a.m.
Session Title: Metabolic Syndrome, Diabetes and Lifestyle Abstract Category: Risk Reduction and Rehabilitation Presentation Number: 1132-117 Authors: Christina A. Chrysohoou, Demosthenes B. Panagiotakos, Christos Pitsavos, John Skoumas, Akis Zeibekis, Christina Kastorini, Constantina Masoura, Efi Tsetsekou, Manolis Kambaxis, Nina Papaioannou, Vasiliki Metaxa, Christodoulos Stefanadis, 1st Cardiology Clinic, Hippokratio, Athens, Greece, Harrokopio University, Athens, Greece Background: No data exist regarding the effect of the Mediterranean diet on renal function. We studied the association between adherence to the Mediterranean diet and markers of renal function, among 3042 people without any evidence of chronic disease. Methods: During 2001-2002, a random sample of 1514 men and 1528 women (18-89 years) from Greece was selected. Urea and creatinine were measured, and creatinine-clearence (CCr) rate was estimated by the Cockcroft-Gault formula. Adherence to the Mediterranean diet was assessed by a validated diet-score (MedDietScore) that incorporated the inherent characteristics of this diet. Results: CCr rate was positively associated with the MedDietScore (b±SE: 0.24±0.09, p=0.007). Moreover, urea and creatinine levels were inversely associated with the MedDietScore (b±SE: -0.05±0.02, p=0.01 and -0.004±0.001, p<0.001, respectively). Multiple linear regression analysis revealed that for each 10/55 additional points in the diet score, a 3.7 unit increase in Ccr rate in women (p<0.001), and a 10.1 unit increase in Ccr rate in men were observed (p<0.001). Further analysis revealed that Ccr rate was positively correlated with the consumption of fruits (rho = 0.08, p=0.009) and moderate alcohol drinking, and inversely correlated with the consumption of potatoes (rho = -0.11, p<0.001), red meat (rho = -0.12, p=0.001) and poultry (rho = -0.07, p=0.02). Conclusions: Greater adherence to the Mediterranean diet was independently associated with reduced urea, creatinine and increased Ccr rates among healthy men and women. This finding, adds to the current knowledge regarding the benefits of the traditional Mediterranean diet on human health.
HYPERTENSION, LIPIDS AND PREVENTION ADHERENCE TO THE MEDITERRANEAN DIET IS ASSOCIATED WITH RENAL FUNCTION AMONG HEALTHY ADULTS: THE ATTICA STUDY ACC Poster Contributions Georgia World Congress Center, Hall B5 Monday, March 15, 2010, 9:30 a.m.-10:30 a.m.
Session Title: Metabolic Syndrome, Diabetes and Lifestyle Abstract Category: Risk Reduction and Rehabilitation Presentation Number: 1132-117 Authors: Christina A. Chrysohoou, Demosthenes B. Panagiotakos, Christos Pitsavos, John Skoumas, Akis Zeibekis, Christina Kastorini, Constantina Masoura, Efi Tsetsekou, Manolis Kambaxis, Nina Papaioannou, Vasiliki Metaxa, Christodoulos Stefanadis, 1st Cardiology Clinic, Hippokratio, Athens, Greece, Harrokopio University, Athens, Greece Background: No data exist regarding the effect of the Mediterranean diet on renal function. We studied the association between adherence to the Mediterranean diet and markers of renal function, among 3042 people without any evidence of chronic disease. Methods: During 2001-2002, a random sample of 1514 men and 1528 women (18-89 years) from Greece was selected. Urea and creatinine were measured, and creatinine-clearence (CCr) rate was estimated by the Cockcroft-Gault formula. Adherence to the Mediterranean diet was assessed by a validated diet-score (MedDietScore) that incorporated the inherent characteristics of this diet. Results: CCr rate was positively associated with the MedDietScore (b±SE: 0.24±0.09, p=0.007). Moreover, urea and creatinine levels were inversely associated with the MedDietScore (b±SE: -0.05±0.02, p=0.01 and -0.004±0.001, p<0.001, respectively). Multiple linear regression analysis revealed that for each 10/55 additional points in the diet score, a 3.7 unit increase in Ccr rate in women (p<0.001), and a 10.1 unit increase in Ccr rate in men were observed (p<0.001). Further analysis revealed that Ccr rate was positively correlated with the consumption of fruits (rho = 0.08, p=0.009) and moderate alcohol drinking, and inversely correlated with the consumption of potatoes (rho = -0.11, p<0.001), red meat (rho = -0.12, p=0.001) and poultry (rho = -0.07, p=0.02). Conclusions: Greater adherence to the Mediterranean diet was independently associated with reduced urea, creatinine and increased Ccr rates among healthy men and women. This finding, adds to the current knowledge regarding the benefits of the traditional Mediterranean diet on human health.