IMPORTANCE OF ABNOFiMAL LUNG EXERCISE VENTILATION IN CHRONIC Osamu Wad3 -----' lshizaka, Medical and
Angeles,
CA..
was 52% * 6s - 71% (p =O.OOl), and sudden
loo-,
90
SR
if3
72 80(1-i
21 L---L
PCW
57
I 15
47
16
60 40;
AF were independently” associated with total f mortality and sudden death. hen stratified
p ~000001
Y-L-L~ Al-
PCW
1.15
20' o;0
--_-A- __.--.A -1c 5 10 15 20 25 30 35 40 d5 50 WEEKS
was associated with a worse 1 yr survival (445 survival (flO’i L’SVi, I), and sudden deat group. Sonciusion: In 1) in the low, but not the high, pts who are well cQmpe~ated despit e LV dysfunction. M portant predictor of mortality and sudden death. Variable prognostic significance in previous studies may be due to the interdependence with hemodynarnic status.
Hidetsu;u
PEPFUSIC~N IN HEART FAILURE
Asanoi, Kyoko Nozaka, Shiqetake Pharmaceutrcal University,
TdkFiShl
M1ya41, s b 1n : 1 Sacayama, TL,b~dRl2 Tn]~%~a, 22;~:
excessld+ ventilbcory res-ponse tLi e>. t .LLt i!2 Whet!lcr related to districutlon of a~~~q perfusion k.2~ e x IT, 1 I; r: d normn. in 23 pts with heart failurc. and 13 age-matched subJects. lisinq tCCtll:ttlaIl:. .,~1it-macr~a39rz~;a:ed ;lb.umi;,, wt~ asst~~;bCd the 1estln.j dlstrrbuticn of pulmonary LlULZ flGW b; scintiyraphic counts ratio of upper t3 lob+r r lunq f1clds. The ver,trlatory rcsi&::sr to exercise WdS assessed 10) the slope of the relation between minute carbon dioxide production (CE-i'Cij;). ventilation and we also, measured maximal reduction in physiclogical exercise. dea? space/tidal volume ratio (Vd/Vt) during 8 pts (Group A) had ?E-\jCCza33, which is the upper limit of normal range and 15 had \jE-<'CO~>33(GrouP E,. Peak cO~(mi/kg/mrn) Vd/Vt change(%) Ul'L(%) -21 t 6 35 +: Normal 24 f 6 -23 ? 7 1824 * 30 27 Group A -6 r12t 60 +2Ot Group B 16+4* (* ~~0.01 vs. Normal, tp