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Agenesis of third molars
131
Abstracts
References [l] V. Bencko, V. Wagner, M. Wagnerova, E. Reichertova, Immunobiochemical findings in groups of individuals occupationally and non-occupationally exposed to emissions containing nickel and cobalt, J. Hyg. Epidemiol. 27 (1983) 3877394. [2] V. Bencko, E.V. Vasilieva, Hygienic and toxicological aspects of occupational and environmental exposure to beryllium, J. Hyg. Epidemiol. 27 (1983) 403-417. [3] V. Bencko, V. Wagner, M. Wagnerova, V. Zavbal, Human exposure to nickel and cobalt: biological monitoring and immunochemical response, Environ. Res. 40 (1986) 399-410. [4] V. Bencko, V. Wagner, M. Wagnerova, J. Batoraj, Immunological profiles in workers of a power plant burning coal of high arsenic content, J. Hyg. Epidemiol. 32 (1988) 137-146. [5] V. Bencko, V. Wagner, M. Wagnerova, V. Ondrejtak, Immunological profiles in workers occupationally exposed to inorganic mercury, J. Hyg. Epidemiol. 34 (1988) 11~ 18. Agenesis
of third
[3] Ch. Schulze, Anomalien und Missbildungen der menschlichen Zlhne, Quintessenz Verlag, Berlin, 1987. AFP
in screening
premature
deliveries
Hurt K, Svoboda B, Pruner R, Rakovicova I Gynecological Clinic University, Srobarova
of the 3rd Faculty 50, 100 34 Prague
of Medicine, Charles IO, Czech Republic
Keywords: AFP; Prematurity; Screening; Delivery A significant statistical correlation between premature deliveries and higher values of MS-AFP has been proven in the 16th week of pregnancy in a group of 1245 patients. We found that in the group of women whose MS-AFP is higher than 1.8 MOM there is a six times higher risk of having premature delivery than in the group of women under 1.8 MOM. This fact can be explained by faster increase in the placental permeability during the pregnancy and faster aging of the whole placenta. The sensitivity of the test is 33%, specificity 93%. Thus, we could define a high-risk group of pregnant women which enables us to reduce number of premature deliveries. Our results allow us to suggest using this test in a broader practice.
molars
Markova Ma, RySava J”, Zvarova Jb “First Faculty of Medicine, The Second Stomatological Clinic, Charles University, Karlovo mimisti 32, 120 00 Prague 2, Czech Republic bEuropean Center for Medical Informatics, Statistics and Epidemiology, Pod vodtirenskou veii 2, 182 07 Prague 8, Czech Republic
Keywords: Hypodontia; Agenesis of third molars; Disorders of dental lamina In 1989- 1991 the authors focused their research on the frequency of agenesis of the third molars in dependence on the frequency of agenesis of the other permanent teeth. They worked with two specially selected groups of patients. The first group consisted of 318 probands with hypodontia of the permanent teeth, where hypodontia of third molars may also be present. The second group consisted of 318 probands without hypodontia of the permanent teeth except for the third molars. The patients were aged from 12 to 20 years. The panoramic rontgenograms of the probands’ teeth were evaluated. A significant difference between males and females was not found. In the first group the authors found agenesis of one to four third molars in 48.7%, in the second one in 21.4% of the cases. It was proved that the frequency of agenesis of the third molars depended only on the number of non-found permanent teeth irrespective of their morphological type. They do not agree with the opinion of some authors [l-3] that the third molars are an indicator of developmental anomalies inclusive of hypodontia. Research supported by the Grant Agency of Charles University no. 209195. References [l] P. Adler, C. Adler-Hradecky, Die Agenesie des Weisheitszahnes, Dtsch. zahnlrztl. Z. 18 (1963) 1361-1369. [2] E. Sonnabend, Zur Unterzahl der Zlhne insbesondere der dritten Molaren, Dtsch. Zahn-Mund-und Kieferheilkd. 46 (1966) 34-43.
The role of endogeuous ischemia
markers
in patients
with lower extremity
ToeSka V, Valenta J, Topolean 0, Pecen L Department Republic
of Surgery,
University
Hospital
Plzen,
Plzen,
Czech
Keywords: Lower extreme choroby; Endogenous markers; Statistics The purpose of this study was to identify a possible influence of some endogenous factors (prostaglandin I 2-PGI 2, thromboxan A 2-TXA 2, beta thromboglobulin-beta TG, endothelin 1,2-ET 1,2), platelet derived growth factor (PDGF) on the progression of atherosclerosis in patients suffering from lower extremity ischemia. The authors examined 123 patients during a 2 year period (1994-1995). Eighty seven patients suffered from claudication or rest pain. Twelve patients had rest pain or gangrene after previous bypass thrombosis. Twenty six patients had abdominal aortic aneurysm (AAA). The average age of patients was 57.4 years (43-82 years). As a control group we examined 60 patients of similar age without clinical manifestation of atherosclerosis. The blood marker levels were evaluated by radioimmunoassay extraction methods. The authors used their own program for data processing. The statistical data were analysed using a non-parametric test (Wilcoxon rank sum test). A higher expression of TXA 2, beta TG, ET 1,2 and PDGF was found in patients suffering from lower extremity ischemia due to progression of atherosclerosis, especially after bypass thrombosis. A statistical significant difference was found between the bypass thrombosis group, the peripheral arterial occlusive disease group and the aneurysm group as compared with the control group (PC 0.05). In summary the results demonstrate the higher expression of ‘atherosclerotic’, prothrombotic endogenous factors in patients who suffered from lower extremity ischemia, especially due to bypass thrombosis. Their elevated blood levels are a predictor of the development of thrombotic complications after vascular reconstruction.
Abstracts
References [l] V. Bencko, V. Wagner, M. Wagnerova, E. Reichertova, Immunobiochemical findings in groups of individuals occupationally and non-occupationally exposed to emissions containing nickel and cobalt, J. Hyg. Epidemiol. 27 (1983) 3877394. [2] V. Bencko, E.V. Vasilieva, Hygienic and toxicological aspects of occupational and environmental exposure to beryllium, J. Hyg. Epidemiol. 27 (1983) 403-417. [3] V. Bencko, V. Wagner, M. Wagnerova, V. Zavbal, Human exposure to nickel and cobalt: biological monitoring and immunochemical response, Environ. Res. 40 (1986) 399-410. [4] V. Bencko, V. Wagner, M. Wagnerova, J. Batoraj, Immunological profiles in workers of a power plant burning coal of high arsenic content, J. Hyg. Epidemiol. 32 (1988) 137-146. [5] V. Bencko, V. Wagner, M. Wagnerova, V. Ondrejtak, Immunological profiles in workers occupationally exposed to inorganic mercury, J. Hyg. Epidemiol. 34 (1988) 11~ 18. Agenesis
of third
[3] Ch. Schulze, Anomalien und Missbildungen der menschlichen Zlhne, Quintessenz Verlag, Berlin, 1987. AFP
in screening
premature
deliveries
Hurt K, Svoboda B, Pruner R, Rakovicova I Gynecological Clinic University, Srobarova
of the 3rd Faculty 50, 100 34 Prague
of Medicine, Charles IO, Czech Republic
Keywords: AFP; Prematurity; Screening; Delivery A significant statistical correlation between premature deliveries and higher values of MS-AFP has been proven in the 16th week of pregnancy in a group of 1245 patients. We found that in the group of women whose MS-AFP is higher than 1.8 MOM there is a six times higher risk of having premature delivery than in the group of women under 1.8 MOM. This fact can be explained by faster increase in the placental permeability during the pregnancy and faster aging of the whole placenta. The sensitivity of the test is 33%, specificity 93%. Thus, we could define a high-risk group of pregnant women which enables us to reduce number of premature deliveries. Our results allow us to suggest using this test in a broader practice.
molars
Markova Ma, RySava J”, Zvarova Jb “First Faculty of Medicine, The Second Stomatological Clinic, Charles University, Karlovo mimisti 32, 120 00 Prague 2, Czech Republic bEuropean Center for Medical Informatics, Statistics and Epidemiology, Pod vodtirenskou veii 2, 182 07 Prague 8, Czech Republic
Keywords: Hypodontia; Agenesis of third molars; Disorders of dental lamina In 1989- 1991 the authors focused their research on the frequency of agenesis of the third molars in dependence on the frequency of agenesis of the other permanent teeth. They worked with two specially selected groups of patients. The first group consisted of 318 probands with hypodontia of the permanent teeth, where hypodontia of third molars may also be present. The second group consisted of 318 probands without hypodontia of the permanent teeth except for the third molars. The patients were aged from 12 to 20 years. The panoramic rontgenograms of the probands’ teeth were evaluated. A significant difference between males and females was not found. In the first group the authors found agenesis of one to four third molars in 48.7%, in the second one in 21.4% of the cases. It was proved that the frequency of agenesis of the third molars depended only on the number of non-found permanent teeth irrespective of their morphological type. They do not agree with the opinion of some authors [l-3] that the third molars are an indicator of developmental anomalies inclusive of hypodontia. Research supported by the Grant Agency of Charles University no. 209195. References [l] P. Adler, C. Adler-Hradecky, Die Agenesie des Weisheitszahnes, Dtsch. zahnlrztl. Z. 18 (1963) 1361-1369. [2] E. Sonnabend, Zur Unterzahl der Zlhne insbesondere der dritten Molaren, Dtsch. Zahn-Mund-und Kieferheilkd. 46 (1966) 34-43.
The role of endogeuous ischemia
markers
in patients
with lower extremity
ToeSka V, Valenta J, Topolean 0, Pecen L Department Republic
of Surgery,
University
Hospital
Plzen,
Plzen,
Czech
Keywords: Lower extreme choroby; Endogenous markers; Statistics The purpose of this study was to identify a possible influence of some endogenous factors (prostaglandin I 2-PGI 2, thromboxan A 2-TXA 2, beta thromboglobulin-beta TG, endothelin 1,2-ET 1,2), platelet derived growth factor (PDGF) on the progression of atherosclerosis in patients suffering from lower extremity ischemia. The authors examined 123 patients during a 2 year period (1994-1995). Eighty seven patients suffered from claudication or rest pain. Twelve patients had rest pain or gangrene after previous bypass thrombosis. Twenty six patients had abdominal aortic aneurysm (AAA). The average age of patients was 57.4 years (43-82 years). As a control group we examined 60 patients of similar age without clinical manifestation of atherosclerosis. The blood marker levels were evaluated by radioimmunoassay extraction methods. The authors used their own program for data processing. The statistical data were analysed using a non-parametric test (Wilcoxon rank sum test). A higher expression of TXA 2, beta TG, ET 1,2 and PDGF was found in patients suffering from lower extremity ischemia due to progression of atherosclerosis, especially after bypass thrombosis. A statistical significant difference was found between the bypass thrombosis group, the peripheral arterial occlusive disease group and the aneurysm group as compared with the control group (PC 0.05). In summary the results demonstrate the higher expression of ‘atherosclerotic’, prothrombotic endogenous factors in patients who suffered from lower extremity ischemia, especially due to bypass thrombosis. Their elevated blood levels are a predictor of the development of thrombotic complications after vascular reconstruction.