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Artificial reproduction of the cyclic changes in cervical mucus in human castrates with clinical correlations
SELECTED
ABSTRACTS
\m. J. Obst. & Gynec. September. 194X
acidosis due to starvation and vomiting, and with elevated blood nonprotein nitrogen, were the rule. In contrast, no patient delivered during the first two days of labor, even though traumatically, died of nonhemorrhagic shock. Uterine rupture occurred only in multiparas, and with equal frequency during version of a large baby, and during spontaneous labor with a normal baby. Nonhemorrhagic shock in retained placenta occurred only after a two- to eight-hour third stage, and was sometimes severe and fatal before placental extraction. There was no death due to removal of the placenta during the first hour, no matter how traumatic. The uterine inversions occurred after a simple third stage, and shock death occurred abruptly with very little bleeding. Bleeding with toxemic uteroplacental apoplexy is variable. With advanced multiparity, the condition is more common and the death rate from shock mounts rapidly. The hypertensive and the cesarean section deaths occurred in patients who lost no blood, and abruptly became severely shocked a few hours post partum. In about one-half of these 147 patients, onset of shock was unavoidable. While one might expect that traumatic vaginal delivery or forcible placental extraction would lead to severe shock, there were no shock deaths in these two groups. In contrast, prolonged labors and prolonged third stages accounted for 76 of the deaths. IRVING L. FRANK.
Miscellamous Abarbanel, A. R.: Artificial Human Castrates With
Reproduction of the Cyclic Changes in Cervical Clinical Correlations, West. J. Surg., p. 26, January,
MUCUS
in
1948.
The author has studied sperm migration in cervical mucus under varied conditions in a great number of patients. In the immediate preovulatory phase corresponding to the temperature drop synchronous with ovulation, there occur the following characteristic changes in cervical mucus: (1) increased volume, (2) decreased viscosity, and (3) absence of leueocytes. Spermatozoa will remain active in this mucus for twenty-four .to seventy-two hours, a much longer time than obtains in the cervical mucus at other times in the cycle. This condition prevails for one to three days. The author studied a group of women who had previously undergone hysterectomy and upon whom bilateral oophorectomy had been done. The physiologic alterations in cervical mucus could be duplicated by a course of therapy simulating the known estrogen curve. In controlled castrates, progesterone and testosterone in the absence of estrogen did not produce these changes. Chronic infection of the endocervix with or without erosion brings about an imreased viscosity of the mucus and is a definite sterility fact,or in women. WILLIAM
Leibovitz, J., and Michael, M.: Fructose, the Sugar Constituent of Human Seminal Preliminary Report, Acta nIedica Orientalia 6: 296-297, 1947.
BICKERS.
Plasma.
The authors, in Jerusalem, used prostatic and vesicular secretions of 12 individuals. hetween the ages of 21 and 46 years, for the purpose of determining the presence, absence. or number of spermatozoa. Two of the patients exhibited azoospermia, another a severe oligospermia. The identification of fructose was carried out according to the method of Selivanoff -van der Haar and Ihl-Pechmann-Diesehe. In all specimens, save one, fructose was found present. There was no difference in the amount of fructose between normal samples and azoospermic specimens. This data, according to the authors, concurs with evidence sub mitted by numerous other authors on the same topic. C. E. FULSOME. Brambell, F. W. R., Hemmings, W. A., and Rowlands, malian Embryo, Lancet, p. X59, Nov. 22, 1947.
W. T.: Immunization
of the Mam-
The yolk sac of seven- and eight-day rabbit embryos contains albumin, alpha, beta, and gamma globulins in proportions similar to maternal plasma, as demonstrated by ele&rQphoresis
ABSTRACTS
\m. J. Obst. & Gynec. September. 194X
acidosis due to starvation and vomiting, and with elevated blood nonprotein nitrogen, were the rule. In contrast, no patient delivered during the first two days of labor, even though traumatically, died of nonhemorrhagic shock. Uterine rupture occurred only in multiparas, and with equal frequency during version of a large baby, and during spontaneous labor with a normal baby. Nonhemorrhagic shock in retained placenta occurred only after a two- to eight-hour third stage, and was sometimes severe and fatal before placental extraction. There was no death due to removal of the placenta during the first hour, no matter how traumatic. The uterine inversions occurred after a simple third stage, and shock death occurred abruptly with very little bleeding. Bleeding with toxemic uteroplacental apoplexy is variable. With advanced multiparity, the condition is more common and the death rate from shock mounts rapidly. The hypertensive and the cesarean section deaths occurred in patients who lost no blood, and abruptly became severely shocked a few hours post partum. In about one-half of these 147 patients, onset of shock was unavoidable. While one might expect that traumatic vaginal delivery or forcible placental extraction would lead to severe shock, there were no shock deaths in these two groups. In contrast, prolonged labors and prolonged third stages accounted for 76 of the deaths. IRVING L. FRANK.
Miscellamous Abarbanel, A. R.: Artificial Human Castrates With
Reproduction of the Cyclic Changes in Cervical Clinical Correlations, West. J. Surg., p. 26, January,
MUCUS
in
1948.
The author has studied sperm migration in cervical mucus under varied conditions in a great number of patients. In the immediate preovulatory phase corresponding to the temperature drop synchronous with ovulation, there occur the following characteristic changes in cervical mucus: (1) increased volume, (2) decreased viscosity, and (3) absence of leueocytes. Spermatozoa will remain active in this mucus for twenty-four .to seventy-two hours, a much longer time than obtains in the cervical mucus at other times in the cycle. This condition prevails for one to three days. The author studied a group of women who had previously undergone hysterectomy and upon whom bilateral oophorectomy had been done. The physiologic alterations in cervical mucus could be duplicated by a course of therapy simulating the known estrogen curve. In controlled castrates, progesterone and testosterone in the absence of estrogen did not produce these changes. Chronic infection of the endocervix with or without erosion brings about an imreased viscosity of the mucus and is a definite sterility fact,or in women. WILLIAM
Leibovitz, J., and Michael, M.: Fructose, the Sugar Constituent of Human Seminal Preliminary Report, Acta nIedica Orientalia 6: 296-297, 1947.
BICKERS.
Plasma.
The authors, in Jerusalem, used prostatic and vesicular secretions of 12 individuals. hetween the ages of 21 and 46 years, for the purpose of determining the presence, absence. or number of spermatozoa. Two of the patients exhibited azoospermia, another a severe oligospermia. The identification of fructose was carried out according to the method of Selivanoff -van der Haar and Ihl-Pechmann-Diesehe. In all specimens, save one, fructose was found present. There was no difference in the amount of fructose between normal samples and azoospermic specimens. This data, according to the authors, concurs with evidence sub mitted by numerous other authors on the same topic. C. E. FULSOME. Brambell, F. W. R., Hemmings, W. A., and Rowlands, malian Embryo, Lancet, p. X59, Nov. 22, 1947.
W. T.: Immunization
of the Mam-
The yolk sac of seven- and eight-day rabbit embryos contains albumin, alpha, beta, and gamma globulins in proportions similar to maternal plasma, as demonstrated by ele&rQphoresis