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AS-268: Comparison of Clinical and Angiographic Profiles between Young and Elderly Women Undergoing Coronary Angiography
April 24 –27, 2012
AS-266 The Predictors of New Stroke in Patients Who Have Undergone Percutaneous Coronary Intervention. Jin Bae Lee, Seung-Pyo Hong, Young Soo Lee, Jae Kern Ryu, Ji Yong Choi, Kee Sik Kim, Sung Gug Chang. Daegu Catholic University Hospital, Daegu, Korea (Republic of). Background: The objective of the present study was to assess the risk factors for stroke in patients who undergone percutaneous coronary intervention. Methods: We conducted a from a 5-year cohort included percutaneous coronary intervention between June 2005 and June 2010. Inclusion criteria were contineous clinical follow up and who have performed follow up agiography. Cases were defined as patients who underwent percutaneous coronary intervention and experienced a stroke during follow up period. Results: Mean follow up duration was 3.46 years. Stroke was developed in 45 of 1168 patients (3.9%). Two significant predictor variables of new onset stroke were age by t-test(68.9 ⫾ 10.4 vs 62.8 ⫾ 10.9, p⬍0.001) and previous history of cerebrovascular disease by 2 test (9.2% vs 3.6%, p⫽0.02). Logistic regression analysis identified two significant independent predictor variables of new stroke were: age ⬎ 70 years (OR, 2.38, p⫽0.005) and previous history of cerebrovascular disease (OR, 2.50, p⫽0.045). Conclusion: In patients who have undergone percutaneous coronary intervention, the independent predictors for new stroke were elderly and previous history of cerebrovascular disease.
AS-267 Prevalence and Pattern of Left Main Coronary Artery Disease in Indian Women. Ezhumalai Babu, Ananthakrishnapillai Ajith, Jaisundar Selvaraj Raja, Gobu Packirisamy, Thulaseedharan Sarojadevi Ashida, Satheesh Santhosh, Jayaraman Balachander. Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India. Background: Stenosis of Left main coronary artery (LMCA) is a relatively uncommon but significant cause of increased morbidity and mortality among patients with coronary artery disease.Our objective is to study the prevalence and pattern of Left Main Coronary Artery (LMCA) disease among Indian women undergoing Coronary Angiography (CAG). Methods: Data of women who underwent CAG in our institute over 3 years from 2008 to 2011 were retrospectively analyzed. The clinical
and angiographic profiles of women with LMCA disease (ⱖ 50% stenosis) were studied. Results: About 500 women underwent CAG over the study period. There were 17 women with ⱖ 50% stenosis of LMCA. The mean age was 58.82⫾6.16 years. There were 11 hypertensives, 10 diabetics, 5 obese women and 8 women with dyslipidemia. All women had attained menopausal state. Mild to moderate but not severe LV dysfunction was seen in 8 women. The majority presented following acute coronary syndromes like myocardial infarction in 6 women, non-ST elevation myocardial infarction in 1 woman and unstable angina in 3 women. The other presenting complaints were typical angina in 6 patients and syncope in 1 woman. 15 (88.24%) out of 17 women had bifurcation lesions involving distal LMCA while the remaining two women had non-bifurcation lesions involving either shaft or ostioproximal part of LMCA. All 10 diabetic women in this study demonstrated bifurcation lesions. There was associated single vessel disease in 1 woman, double vessel disease in 2 women and triple vessel disease in 10 women among those 15 with bifurcation lesions. Conclusion: The prevalence of LMCA disease among Indian women undergoing coronary angiography is 3.4%. Bifurcation lesion involving distal LMCA associated with triple vessel disease in postmenopausal diabetic woman is the most common presentation.
AS-268 Comparison of Clinical and Angiographic Profiles between Young and Elderly Women Undergoing Coronary Angiography. Ezhumalai Babu, Ananthakrishnapillai Ajith, Gobu Packirisamy, Thulaseedharan Sarojadevi Ashida, Jaisundar Selveraj Raja, Satheesh Santhosh, Jayaraman Balachander. Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India. Background: In the last decade, there has been a significant rise in the proportion of women undergoing angiography. There are not many studies on the changing pattern of clinical and angiographic profiles of women undergoing coronary angiography. Our objective is to study the clinical and angiographic profiles of women undergoing coronary angiography. Methods: Clinical and angiographic profiles of 500 women who underwent coronary angiogram over 3 years between August 2008 and July 2011 in our institute were retrospectively analyzed. They were classified into Young group (age ⬍ 55 years) and Elderly group (age ⱖ 55years). Results: There were 257 women in the young group and 243 women in the elderly group (p⫽0.4110). The mean age was 47.03⫾5.12 years and 60.82⫾4.96 years for young women and elderly women respectively. There were more hypertensives in elderly group than young group (159 vs. 142, p⫽0.0256). There were no differences with respect to diabetes, obesity and dyslipidemia between two groups. LV dysfunction was more common in elderly women than young women (67 vs. 44, p⫽0.069). Though presentation following acute coronary syndromes were similar in both groups, young women presented more commonly with typical angina (134 vs. 104, p⫽0.0454). Coronary angiogram showed normal epicardial coronaries and Cardiac Syndrome X more prevalent in young women than elderly (133 vs. 88). Left main coronary artery disease (15 vs. 2), double vessel disease (85 vs. 43) and triple vessel disease (84 vs. 46) were more common in elderly group. The proportion of women with single vessel disease was not different between two groups. Conclusion: There is an alarming increase in the proportion of young women with atherosclerotic risk factors undergoing coronary angiogram. It is essential to identify coronary artery disease in these women and treat them more aggressively to prevent devastating cardiovascular events.
The American Journal of Cardiology姞 APRIL 24 –27, 2012 ANGIOPLASTY SUMMIT ABSTRACTS/Poster
131S
P O S T E R A B S T R A C T S
AS-266 The Predictors of New Stroke in Patients Who Have Undergone Percutaneous Coronary Intervention. Jin Bae Lee, Seung-Pyo Hong, Young Soo Lee, Jae Kern Ryu, Ji Yong Choi, Kee Sik Kim, Sung Gug Chang. Daegu Catholic University Hospital, Daegu, Korea (Republic of). Background: The objective of the present study was to assess the risk factors for stroke in patients who undergone percutaneous coronary intervention. Methods: We conducted a from a 5-year cohort included percutaneous coronary intervention between June 2005 and June 2010. Inclusion criteria were contineous clinical follow up and who have performed follow up agiography. Cases were defined as patients who underwent percutaneous coronary intervention and experienced a stroke during follow up period. Results: Mean follow up duration was 3.46 years. Stroke was developed in 45 of 1168 patients (3.9%). Two significant predictor variables of new onset stroke were age by t-test(68.9 ⫾ 10.4 vs 62.8 ⫾ 10.9, p⬍0.001) and previous history of cerebrovascular disease by 2 test (9.2% vs 3.6%, p⫽0.02). Logistic regression analysis identified two significant independent predictor variables of new stroke were: age ⬎ 70 years (OR, 2.38, p⫽0.005) and previous history of cerebrovascular disease (OR, 2.50, p⫽0.045). Conclusion: In patients who have undergone percutaneous coronary intervention, the independent predictors for new stroke were elderly and previous history of cerebrovascular disease.
AS-267 Prevalence and Pattern of Left Main Coronary Artery Disease in Indian Women. Ezhumalai Babu, Ananthakrishnapillai Ajith, Jaisundar Selvaraj Raja, Gobu Packirisamy, Thulaseedharan Sarojadevi Ashida, Satheesh Santhosh, Jayaraman Balachander. Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India. Background: Stenosis of Left main coronary artery (LMCA) is a relatively uncommon but significant cause of increased morbidity and mortality among patients with coronary artery disease.Our objective is to study the prevalence and pattern of Left Main Coronary Artery (LMCA) disease among Indian women undergoing Coronary Angiography (CAG). Methods: Data of women who underwent CAG in our institute over 3 years from 2008 to 2011 were retrospectively analyzed. The clinical
and angiographic profiles of women with LMCA disease (ⱖ 50% stenosis) were studied. Results: About 500 women underwent CAG over the study period. There were 17 women with ⱖ 50% stenosis of LMCA. The mean age was 58.82⫾6.16 years. There were 11 hypertensives, 10 diabetics, 5 obese women and 8 women with dyslipidemia. All women had attained menopausal state. Mild to moderate but not severe LV dysfunction was seen in 8 women. The majority presented following acute coronary syndromes like myocardial infarction in 6 women, non-ST elevation myocardial infarction in 1 woman and unstable angina in 3 women. The other presenting complaints were typical angina in 6 patients and syncope in 1 woman. 15 (88.24%) out of 17 women had bifurcation lesions involving distal LMCA while the remaining two women had non-bifurcation lesions involving either shaft or ostioproximal part of LMCA. All 10 diabetic women in this study demonstrated bifurcation lesions. There was associated single vessel disease in 1 woman, double vessel disease in 2 women and triple vessel disease in 10 women among those 15 with bifurcation lesions. Conclusion: The prevalence of LMCA disease among Indian women undergoing coronary angiography is 3.4%. Bifurcation lesion involving distal LMCA associated with triple vessel disease in postmenopausal diabetic woman is the most common presentation.
AS-268 Comparison of Clinical and Angiographic Profiles between Young and Elderly Women Undergoing Coronary Angiography. Ezhumalai Babu, Ananthakrishnapillai Ajith, Gobu Packirisamy, Thulaseedharan Sarojadevi Ashida, Jaisundar Selveraj Raja, Satheesh Santhosh, Jayaraman Balachander. Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India. Background: In the last decade, there has been a significant rise in the proportion of women undergoing angiography. There are not many studies on the changing pattern of clinical and angiographic profiles of women undergoing coronary angiography. Our objective is to study the clinical and angiographic profiles of women undergoing coronary angiography. Methods: Clinical and angiographic profiles of 500 women who underwent coronary angiogram over 3 years between August 2008 and July 2011 in our institute were retrospectively analyzed. They were classified into Young group (age ⬍ 55 years) and Elderly group (age ⱖ 55years). Results: There were 257 women in the young group and 243 women in the elderly group (p⫽0.4110). The mean age was 47.03⫾5.12 years and 60.82⫾4.96 years for young women and elderly women respectively. There were more hypertensives in elderly group than young group (159 vs. 142, p⫽0.0256). There were no differences with respect to diabetes, obesity and dyslipidemia between two groups. LV dysfunction was more common in elderly women than young women (67 vs. 44, p⫽0.069). Though presentation following acute coronary syndromes were similar in both groups, young women presented more commonly with typical angina (134 vs. 104, p⫽0.0454). Coronary angiogram showed normal epicardial coronaries and Cardiac Syndrome X more prevalent in young women than elderly (133 vs. 88). Left main coronary artery disease (15 vs. 2), double vessel disease (85 vs. 43) and triple vessel disease (84 vs. 46) were more common in elderly group. The proportion of women with single vessel disease was not different between two groups. Conclusion: There is an alarming increase in the proportion of young women with atherosclerotic risk factors undergoing coronary angiogram. It is essential to identify coronary artery disease in these women and treat them more aggressively to prevent devastating cardiovascular events.
The American Journal of Cardiology姞 APRIL 24 –27, 2012 ANGIOPLASTY SUMMIT ABSTRACTS/Poster
131S
P O S T E R A B S T R A C T S