SELECTED
113
ABSTRACTS
In one serum a trace of antibody was evident with antigen diluted 1:20 serum definite prec,ipitate could be observed with antigen diluted 1:640. studies in four of the nine animals sensitized with egg whit,e revealed precipitate in one animal when tested with a.ntigen diluted 1:lOO. The minimum lethal .dose of histamine mately 0.8 mg. per 100 Gm. for the cotton required to kill a guinea pig, but is one been reported lethal for the rat.
Evaluation
of the Tuberculin
J. Dis.
Child.
60:
631,
Patch
; in another Precipitin a trace of
administered intravenously was approxirat. This is fifteen times the quantity hundred times less than that which has
Test.
Fineman,
A.
H.,
and
Bair,
G.:
Am.
1940.
Three hundred and thirty children, ranging in age, from 4 were studied in order to determine the reliability of the patch as compared with the Pirquet and Mantoux tests. If it was negative, The Pirquet test was performed first. test and the Mant,oux test (0.1 mg. 0. T.) were performed eight hours later on the upper and inner part of the same were made at forty-eight hours and as late as from four to test.
months to 14 years, test with tuberculin the tuberculin patch simultaneously fortyforearm. Rea,dings seven days after the
Results of the Pirquet and patch tests agreed in 313 patients, or 95 per cent, Of these sevent,een patients, fourteen and disagreed in seventeen, or 5 per cent. were positive to the patch test and negative to the Pirquet test. Eleven of these fourteen patients showed positive reactions to the Mantoux test. Results of the patch and Mantoux tests agreed in 278 patients, or 97 per cent, and disagreed in nine, or three per cent. Six of these nine patients reacted negatively to the patch test and positively to the Mantoux test. Three children showed positive reactions to the patch test and negative reactions to the Mantoux test. In some instances a faint erythema or negative reaction to the patch test at forty-eight hours became de:finitely positive at ninety-six hours. The
authors conclude that the tuberculin and is somewhat more sensitive than t.ive than the Mantoux. For routine work, initial test in place of the Pirquet. If it Mantoux test with 0.1 mg. 0. T. is advised.
patch test the Pirquet the patch is negative
liable,
is
simple, practical, and retest and slightly less sensitest is recommended as the at the end of one week, a
Pediatrics UNDER
Asthma Brit.
THE
DIRECTIOP;
OF WILLIAM
in Childhood:
A Diecussion
M.
1940.
J. 2:
1028,
C.
DEAXER,
M.D.,
of the Psychological
SAN
Aspect.
FRANCISCO
Hall,
M.
B.:
After reviewing the literature on the psychologic aspects of asthma., the author illustrates the subject with five case reports dealing with children. In each instance the, patient was referred by another physician for psychologic investigation. Treatment of a psychologic nature was directed at the parents as well as the patient. All patients were well above average intelligence and had personality traits which have been described as occurring in the allergic group. The five patients improved under treatment, and no other form of therapy was used during the time they were under observation. The children were from 9 to 15 years of age, and a family history of allergy was present in each instance. The desirability of employing psychologic methods of treatment in selected cases of asthma is stressed.