Basic medical endocrinology

Basic medical endocrinology

Vol. 32, No. 2, pp. 335-337, Pergamon Press plc. Printed in Great Britain J. steroid Biochem. 1989 BOOK REVIEWS Methods ia Enzymology. Editors-in-...

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Vol. 32, No. 2, pp. 335-337, Pergamon Press plc. Printed in Great Britain

J. steroid Biochem.

1989

BOOK REVIEWS

Methods ia Enzymology. Editors-in-Chief: J. N. Abelson and M. I. Simon. Vol. 152: Guide to Molecular Clonine Techniques. Edited by SHELBYL. BERGERand ALAN < KIMMEL. Published September 1987 by Academic Press, U.S.A. No. of pages: 854. Price: $89.00. ISBN: 0-12-182053-X. The recombinant DNA technology has opened a new era in molecular biology with fascinating applications in different fields of biology. This book contains up-to-date information concerning all the practical and theoretical aspects of recombinant DNA. The main sections include: -Requirements for a Molecular Biology Laboratory -General Methods for Isolating and Characterizing Nucleic Acids -Enzymatic Techniques and Recombinant DNA Technology -Restriction Enzymes Growth and Maintenance of Bacteria -Genomic Cloning -Preparation and Characterization of RNA -Preparation of cDNA and the Generation of cDNA libraries -Selection of Clones from Libraries -Identification and Characterization of Specific Clones. The book has been written by eminent scientists in this field and would be very useful for researchers, students, biologists, physiologists, and all people working on molecular biology.

Hormones, Cell Biology, aod Cancer Perspectives and Poteatials. Pmgress in clinical nad Biological Researe&Vol. 262. Edited by W. DAVIDHANKINSand DAVIDPuzrr. Published February 1988 by Alan R. Liss, New York. No. of pages: 316. Price as at February 1988: $60.00. ISBN: O-8451-5112-6. This volume contains the Proceedings of a Satellite Symposium of the 1986 American Society for Cell Biology Meeting, held in Washington DC on 7th December 1986. In recent years it has been very well established that cancerization of endocrine glands is the result of different parameters which include hormone action, autocrine and paracrine growth factors, oncogenes, etc. As the main factor of cancerization is the hormone, the pharmaceutical production of anti-hormones has one of the most important impacts for the treatment of this kind of disease. This book contains up-to-date information on all these problems and the main chapters concern Steroid Hormones and Receptors and Peptide Hormones and Receptor, including the following specific topics: -From cell proliferation to differentiation: the steroid connection -Combination therapy with flutamide and (D-Trp6, DESGLY-NH:‘]LHRH ethylamide in stage C and D prostate cancer: todays therapy of choice-rationale and 5-year clinical experience -Aromatase and aromatase inhibitors: from enzymology to selective chemotherapy -Estrogens and antiestrogens mediate contrasting transitions in estrogen receptor conformation which determine

chromatin access: a review and synthesis of recent observations -Long-term tamoxifen therapy to control or to prevent breast cancer: laboratory concept to clinical trials -Estrogen receptor in human prostate: assay conditions for quantitation -Validation of the exchange assay for the measurement of androgen receptors in human and dog prostates -Progestin effects on lactate dehydrogenase and growth in the human breast cancer cell line T47D -The cellular response of human breast cancer to estrogen -Cellular endocrinology and cancer -Epidermal growth factor -Use of analogs of LH-RH and somatostatin for the treatment of hormone dependent cancers -Multi-hormonal regulation of tyrosinase expression in B16/C3 melanoma cells in culture -Hormone associated therapy of leukemia: reflections -Human B cell growth factor and neoplasia -The role of the multichain IL-2 receptor complex in the control of normal and malignant T-cell proliferation These chapters have been written by pioneers in this scientific field and the book will be of interest to oncologists, gynecologists, physiologists, general clinicians and advanced students.

Basic Medical Endocrinology. Edited by H. MAURICE GOODMAN.Raven Press Series in Physiology. Series Editor: WILLIAMF. GANONG.Published 1988 by Raven Press, New York. No. of pages: 360. Retail Price as of June 1988: $36.50 (paper), $61.50 (hardcover). ISBN: 0-88167-412-5-0-88167-395-1 (soft). This book contains the basics of biological and physiological functions of hormones in different target tissues. It gives a general idea of how hormones work and the interaction of hormones with other substances including growth factors. It is a very interesting book with up-to-date information on general problems of endocrinology and would be very useful to people working in endocrinology, molecular endocrinology, physiology, and biology, as well as for advanced students.

Osteoporosis. Etiology, Diagnosis aod Management. Edited by B. LAWRENCERIGGSand L. JOSEPHMELTONIII. Published December 1987 by Raven Press, New York. No. of pages: 515. Price as of March 1988: S110.00. ISBN: 0-88167-350-l. It is not a long time ago that osteoporosis was considered as an untreatable and inevitable consequence of old age. However, recent enormous progress on the mechanical process and the knowledge of factors involved in osteoporosis has allowed to avoid the drastic consequences of this disease using efficient treatment with different drugs, including mainly different hormones. This book gives up-to-date information on basic science, clinical aspects, pathophysiology, and management of osteoporosis. It contains the following main topics: -The cells of bone

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