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Benign Lymphoid Hyperplasia of the Tongue
ORAL AND MAXILLOFACIAL PATHOLOGY e78 Abstracts PCC-272 - BENIGN LYMPHOID HYPERPLASIA OF THE TONGUE. KARIN BERRIA TOMAZELLI, MARIA INÊS MEURER, LILIANE JANETE GRANDO, VICTOR LOUSAN DO NASCIMENTO POUBEL, ELENA RIET CORREA RIVERO. UNIVERSIDADE FEDERAL DE SANTA CATARINA. Benign lymphoid hyperplasia (BLH) of the tongue is a rare benign lymphoproliferative lesion that, histopathologically, resembles a lymphoma. An 8-year-old female presented with a firm, painless, non-ulcerated, and slow-growing swelling on the ventral surface of the tongue. The medical history included a liver transplant performed at 10 months of age and current use of immunosuppression therapy. An excisional biopsy was performed, and the microscopic examination showed multiple germinal centers with a rim of small mature lymphocytes, together with a mixed, mainly mononuclear, infiltrate. Although BLH must be distinguished from a neoplastic lymphoid proliferation, primarily follicular lymphoma, the histological features at the present case were those of a typical BLH, causing no difficulty in the diagnosis and requiring no further investigation. During follow-up, the patient showed no signs of recurrence.
PCC-273 - BISPHOSPHONATE-RELATED OSTEONECROSIS HANDLING WITH LOW-LEVEL LASER THERAPY. KARIN BERRIA TOMAZELLI, MARIANA COMPAROTTO MINAMISAKO, MARIA INÊS MEURER, AIRA MARIA BONFIM SANTOS, MARIÁH LUZ LISBOA, INÊS BEATRIZ DA SILVA RATH, LILIANE JANETE GRANDO. UNIVERSIDADE FEDERAL DE SANTA CATARINA. Osteonecrosis of the jaw has been associated with the use of bisphosphonates, which modify the mechanism of bone resorption and remodeling. An 85-year-old male was referred for evaluation of exposed bone in the region of teeth #13, #15, and #28, which had been extracted 24 months earlier. Radiography showed bone lysis with sequestrum. The medical history revealed use of alendronate sodium (75 mg/week) due to a prosthetic knee. Thus, a diagnosis of bisphosphonate-related osteonecrosis was made. The treatment began with clindamycin (900 mg/day) and periodic sequestrectomy, followed by low-level laser therapydinfrared light (l ¼ 808 nm; 100 mW power; fluency 142 J/cm2) at 12 points in the superior alveolar process and red light (l ¼ 660 nm; 100 mW power; fluency 35 J/cm2) at 6 points distributed around the injurydin weekly sessions due to patient difficulty in traveling to the clinic. After 9 months, there was a significant reduction of bone exposure and there was no pain or suppuration.
PCC-274 - CROHN’S DISEASE: ORAL LESIONS AS THE MAIN SIGNS. JOSÉ FERREIRA DE MENEZES FILHO, VIVIANE SILVA SIQUEIRA, ANELISE RIBEIRO PEIXOTO ALENCAR, ANDRESSA BORGES, FABRÍCIO PASSADOR SANTOS. HOSPITAL REGIONAL DE ARAGUAÍNA/FACULDADE DE CIÊNCIAS DO TOCANTINS. Crohn’s disease is considered an inflammatory, immunemediated gastrointestinal disease involving the digestive tract from oral cavity to anus that can ulcerate portions of the distal small intestine and colon. Oral cavity lesions are represented by deep linear ulcers or rubbery swellings of the lips and oral mucosa. We report the case of a female patient who had, 4 years earlier, been diagnosed with ulcerative colitis with no oral symptomatology. In the last 3 months, she had been seeking dental care, complaining of persistent swellings on the lower lip and, most recently, nodular masses in the buccal mucosa. The patient reported only sparse, mild intestinal sores. Biopsies were
OOOO August 2015 taken from the lower lip and buccal mucosa. Histopathological analysis of the biopsy specimens showed non-necrotizing granulomas, suggestive of Crohn’s disease. Clinical photos and photomicrographs allowed the final diagnosis to be made.
PCC-275 - CLEIDOCRANIAL DYSPLASIA: REPORT OF 3 CASES IN THE SAME FAMILY. EUTON JEFFERSON GOMES DE AZEVEDO, CASSIANO FRANCISCO WEEGE NONAKA, FRANCISCO JADSON LIMA, MANUEL ANTONIO GORDÓN-NÚÑEZ, ALAN VICTOR ALVES DOS SANTOS, MARIA DO ROSÁRIO DA SILVA FLOR, FERNANDO ANTONIO PORTELA DA CUNHA FILHO. UNIVERSIDADE ESTADUAL DA PARAÍBA. Cleidocranial dysplasia is a genetic autosomal dominant disorder, with high penetrance and variable expression, characterized by alteration in the skeletal and teeth development. It occurs in the same frequency for both genders and races. This report describes 3 cases of cleidocranial dysplasia in the same family, addressing clinical and radiographic issues from diagnosis to dental treatment. The 3 cases were presented with pathognomonic clinical features, as follows: low stature; appearance of long neck and sloping shoulders; maxillary hypoplasia; clavicular aplasia; and dental alterations such as supernumerary and unerupted teeth. Early detection of this disease is essential to determining the proper treatment, minimizing probable surgical interventions that might be needed and providing a better quality of life for the patients.
PCC-276 - CYSTIC ODONTOMA IN PATIENT TREATED WITH VINCRISTINE AND CYCLOPHOSPHAMIDE. VICTOR BERNARDES BARROSO DA COSTA, LUCIANA ROCHA STRIEDER, ADRIANA ROCHA DE CARIS, VANESKA MACHADO GUIMARÃES JARDINI, JORGE ESQUICHE LEÓN, ESTELA KAMINAGAKURA TANGO. FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS e UNESP. Cystic odontoma is a rare entity, characterized by the combination of cyst and complex odontoma. We report the case of a 5year-old male diagnosed with Hodgkin’s lymphoma who was treated with vincristine and cyclophosphamide. Physical examination revealed a swelling on the right side of mandible. Radiographically, a well-defined radiolucent area with radiopaque material was observed. An incisional biopsy was performed under the hypothesis of odontogenic tumor or odontogenic cystic lesion. Microscopically, the specimen exhibited a slender epithelium with 2e3 cell layers, without inflammation in the connective tissue. The provisional diagnosis of odontogenic cystic lesion was made. The cyst was decompressed, and, after 3 months, it was removed. Analysis of the surgical specimen showed cystic epithelium and mineralized tissue similar to dentin and cementum. The final diagnosis was cystic odontoma. In this case, the influence of chemotherapy in the pathogenesis of cystic odontoma should be considered.
PCC-277 - DIAGNOSIS OF TUBERCULOSIS FROM AN ORAL LESION. HELENE DOS SANTOS CARVALHO PEREIRA, NATHÁLIA DE ALMEIDA FREIRE, SARAH APARECIDA ANTERO, FÁBIO RAMOA PIRES, MARIA ELIZA BARBOSA RAMOS, MÔNICA SIMÕES ISRAEL, ROSEMIRO DE MENEZES MACIEL. UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO. Tuberculosis is a chronic infectious disease that most often affects the lungs but can involve any organ or tissue, such as the oral cavity. A 54-year-old black male sought treatment at our
PCC-273 - BISPHOSPHONATE-RELATED OSTEONECROSIS HANDLING WITH LOW-LEVEL LASER THERAPY. KARIN BERRIA TOMAZELLI, MARIANA COMPAROTTO MINAMISAKO, MARIA INÊS MEURER, AIRA MARIA BONFIM SANTOS, MARIÁH LUZ LISBOA, INÊS BEATRIZ DA SILVA RATH, LILIANE JANETE GRANDO. UNIVERSIDADE FEDERAL DE SANTA CATARINA. Osteonecrosis of the jaw has been associated with the use of bisphosphonates, which modify the mechanism of bone resorption and remodeling. An 85-year-old male was referred for evaluation of exposed bone in the region of teeth #13, #15, and #28, which had been extracted 24 months earlier. Radiography showed bone lysis with sequestrum. The medical history revealed use of alendronate sodium (75 mg/week) due to a prosthetic knee. Thus, a diagnosis of bisphosphonate-related osteonecrosis was made. The treatment began with clindamycin (900 mg/day) and periodic sequestrectomy, followed by low-level laser therapydinfrared light (l ¼ 808 nm; 100 mW power; fluency 142 J/cm2) at 12 points in the superior alveolar process and red light (l ¼ 660 nm; 100 mW power; fluency 35 J/cm2) at 6 points distributed around the injurydin weekly sessions due to patient difficulty in traveling to the clinic. After 9 months, there was a significant reduction of bone exposure and there was no pain or suppuration.
PCC-274 - CROHN’S DISEASE: ORAL LESIONS AS THE MAIN SIGNS. JOSÉ FERREIRA DE MENEZES FILHO, VIVIANE SILVA SIQUEIRA, ANELISE RIBEIRO PEIXOTO ALENCAR, ANDRESSA BORGES, FABRÍCIO PASSADOR SANTOS. HOSPITAL REGIONAL DE ARAGUAÍNA/FACULDADE DE CIÊNCIAS DO TOCANTINS. Crohn’s disease is considered an inflammatory, immunemediated gastrointestinal disease involving the digestive tract from oral cavity to anus that can ulcerate portions of the distal small intestine and colon. Oral cavity lesions are represented by deep linear ulcers or rubbery swellings of the lips and oral mucosa. We report the case of a female patient who had, 4 years earlier, been diagnosed with ulcerative colitis with no oral symptomatology. In the last 3 months, she had been seeking dental care, complaining of persistent swellings on the lower lip and, most recently, nodular masses in the buccal mucosa. The patient reported only sparse, mild intestinal sores. Biopsies were
OOOO August 2015 taken from the lower lip and buccal mucosa. Histopathological analysis of the biopsy specimens showed non-necrotizing granulomas, suggestive of Crohn’s disease. Clinical photos and photomicrographs allowed the final diagnosis to be made.
PCC-275 - CLEIDOCRANIAL DYSPLASIA: REPORT OF 3 CASES IN THE SAME FAMILY. EUTON JEFFERSON GOMES DE AZEVEDO, CASSIANO FRANCISCO WEEGE NONAKA, FRANCISCO JADSON LIMA, MANUEL ANTONIO GORDÓN-NÚÑEZ, ALAN VICTOR ALVES DOS SANTOS, MARIA DO ROSÁRIO DA SILVA FLOR, FERNANDO ANTONIO PORTELA DA CUNHA FILHO. UNIVERSIDADE ESTADUAL DA PARAÍBA. Cleidocranial dysplasia is a genetic autosomal dominant disorder, with high penetrance and variable expression, characterized by alteration in the skeletal and teeth development. It occurs in the same frequency for both genders and races. This report describes 3 cases of cleidocranial dysplasia in the same family, addressing clinical and radiographic issues from diagnosis to dental treatment. The 3 cases were presented with pathognomonic clinical features, as follows: low stature; appearance of long neck and sloping shoulders; maxillary hypoplasia; clavicular aplasia; and dental alterations such as supernumerary and unerupted teeth. Early detection of this disease is essential to determining the proper treatment, minimizing probable surgical interventions that might be needed and providing a better quality of life for the patients.
PCC-276 - CYSTIC ODONTOMA IN PATIENT TREATED WITH VINCRISTINE AND CYCLOPHOSPHAMIDE. VICTOR BERNARDES BARROSO DA COSTA, LUCIANA ROCHA STRIEDER, ADRIANA ROCHA DE CARIS, VANESKA MACHADO GUIMARÃES JARDINI, JORGE ESQUICHE LEÓN, ESTELA KAMINAGAKURA TANGO. FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS e UNESP. Cystic odontoma is a rare entity, characterized by the combination of cyst and complex odontoma. We report the case of a 5year-old male diagnosed with Hodgkin’s lymphoma who was treated with vincristine and cyclophosphamide. Physical examination revealed a swelling on the right side of mandible. Radiographically, a well-defined radiolucent area with radiopaque material was observed. An incisional biopsy was performed under the hypothesis of odontogenic tumor or odontogenic cystic lesion. Microscopically, the specimen exhibited a slender epithelium with 2e3 cell layers, without inflammation in the connective tissue. The provisional diagnosis of odontogenic cystic lesion was made. The cyst was decompressed, and, after 3 months, it was removed. Analysis of the surgical specimen showed cystic epithelium and mineralized tissue similar to dentin and cementum. The final diagnosis was cystic odontoma. In this case, the influence of chemotherapy in the pathogenesis of cystic odontoma should be considered.
PCC-277 - DIAGNOSIS OF TUBERCULOSIS FROM AN ORAL LESION. HELENE DOS SANTOS CARVALHO PEREIRA, NATHÁLIA DE ALMEIDA FREIRE, SARAH APARECIDA ANTERO, FÁBIO RAMOA PIRES, MARIA ELIZA BARBOSA RAMOS, MÔNICA SIMÕES ISRAEL, ROSEMIRO DE MENEZES MACIEL. UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO. Tuberculosis is a chronic infectious disease that most often affects the lungs but can involve any organ or tissue, such as the oral cavity. A 54-year-old black male sought treatment at our