- Email: [email protected]
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Biocatalysis and biotransformation Bioinorganic chemistry Web alert Grace R Nakayama A selection of World Wide Web sites relevant to papers published in this issue of Current Opinion in Chemical Biology. Current Opinion in Chemical Biology 2002, 6:121–122 Addresses Pfizer Global Research and Development, La Jolla Laboratories, 10770 Science Center Drive, San Diego, CA 92121 USA; e-mail: [email protected]
Introduction to Biotransformation http://www.sci.tamucc.edu/pals/moslen/garvish/ Biotransformation: species differences and determining factors http://www.sci.tamucc.edu/pals/moslen/dominski/sld001.htm These lecture notes cover topics in biotransformation. They were prepared by John F Garvish and Tammy Domanski, respectively, at Texas A&M University, Corpus Christi (USA).
Biocatalysis and biotransformation
Bioinorganic chemistry
Biocatalysis http://www.nature.com/nature/insights/6817.html Several review articles about biocatalysis appeared in this issue of Nature Insight, which was published in 2001. These articles are available for free to subscribers of Nature or can be purchased individually.
Metalloprotein Site Database and Browser http://metallo.scripps.edu/ The Metalloprotein Site Database and Browser (MDB) compiles information from the Protein Data Bank (PDB) pertaining to metal-binding sites. This database may be searched by entering queries based on geometric and molecular characteristics. In addition, tools are available to visualize structures and analyze quantitative data. The MDB is part of the Metalloprotein Structure, Bioinformatics and Design Program (http://www.scripps.edu/research/metallo/) at The Scripps Research Institute (USA).
Biocatalysis: chemical and pharmaceutical makers seek more efficient and often cleaner routes to making old and new products http://pubs.acs.org/cen/coverstory/7921/7921biocatalysis.html Making drugs with little bugs http://pubs.acs.org/cen/coverstory/7921/7921biocatalysis2.html Biocatalysis: Japan’s unique perspective http://pubs.acs.org/cen/coverstory/7921/7921biocatalysis3.html Chemical and Engineering News published a special report about biocatalysis in the May 21, 2001 issue. These articles were written by Ann M Thayer, Michael McCoy and Jean-François Tremblay, respectively. CSE Links: Directed Evolution http://www.biols.susx.ac.uk/CSE/Links/directed.html Links about directed in vitro molecular evolution are categorized by background, protein evolution, RNA evolution, commercial, journals, and general. They were compiled by the Centre for the Study of Evolution (CSE) at University of Sussex (UK). ExtremoFiles http://www.ualberta.ca/~csotonyi/extremophiles/index.html http://www.crosswinds.net/~juliuscsotonyi/extremophiles Julius T Csotonyi of the Department of Biological Sciences, University of Alberta (Canada) has compiled a number of resources related to extremophiles. They are organized into the following categories: community, databases, education, encyclopedia, events, images, links and literature. The International Society for Extremophiles http://extremophiles.org/ The mission statement of the International Society for Extremophiles is “to advance for the worldwide benefit of people, the science of extremophiles, particularly, life under extreme environments and its applications to the environment, agriculture and industry”. The fourth international congress, Extremophiles2002, will be held in Naples, Italy in Sept 2002 (http://www.extremophiles2002.it/).
Prion Science Archives http://www.mad-cow.org/00/sci_archive_frame.html For the past five years, the Prion Science Archives have collected information about prions. A large number of resources have been organized by the following topics: human genome project and disease genes, conformational diseases (amyloidoses), prion and doppel genes, prion protein, specific diseases, and general interest. This site is sponsored by of the Sperling Biomedical Foundation and is maintained by Michael Greger. It is part of the Official Mad Cow Disease Home Page (http://www.mad-cow.org/~tom/). The PROMISE Database http://bmbsgi11.leeds.ac.uk/promise/MAIN.html/original UK site http://metallo.scripps.edu/PROMISE/mirror US site PROMISE (PROsthetic groups and Metal Ion SitEs in proteins) is a searchable database containing information about prosthetic groups and ion sites in proteins. Major categories include chlorophyll proteins, copper proteins, diiron-carboxylate proteins, haem proteins, iron–sulphur proteins, mononuclear iron proteins, and molybdopterin-containing proteins. Note: the PROMISE database, which is maintained at the University of Leeds (UK), has not been updated since 1999.
Journals Journal of Inorganic Biochemistry http://www.elsevier.nl/inca/publications/store/5/0/5/7/7/2/ http://www.chemweb.com/library/elsevier/effect/display.exe?jc ode=jib Table of contents and abstracts are available for free. Full text of articles is available for subscribers via ChemWeb.
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Web alert
Biocatalysis and Biotransformation http://www.tandf.co.uk/journals/titles/10242422.html Table of contents, abstracts and article references are available for free. Full text of articles is available to subscribers.
Journal of Molecular Evolution http://link.springer.de/link/service/journals/00239/index.htm Table of contents and abstracts are available for free. Full text of articles is available for subscribers.
Extremophiles: Life Under Extreme Conditions http://link.springer.de/link/service/journals/00792/ Table of contents, abstracts and sample issue are available for free. Full text of articles is available to subscribers.
Nature Structural Biology http://structbio.nature.com/ Table of contents and abstracts are available for free. Full text of articles is available for subscribers.
Journal of Biological Inorganic Chemistry http://link.springer.de/link/service/journals/00775/index.htm Table of contents and abstracts are available for free. Full text of articles is available for subscribers.
Structure http://www.structure.org/ Table of contents and abstracts are available for free. Full text of articles is available for subscribers or for a per-item fee.
Newsletters — a new service from BioMedNet, Current Opinion and Trends Now available, direct to your e-mail box: FREE e-mail newsletters highlighting the latest developments in rapidly moving fields of research. A team of editors from the Current Opinion and Trends journals have combined to compile the Biopharmaceuticals Newsletter — from monoclonal antibodies and recombinant proteins to regulatory affairs and clinical trials. Each newsletter features news articles from the BioMedNet newsdesk, as well as highlights from the review content of the Current Opinion and Trends journals. Access to full-text journal articles is available through your institution. Newsletters are sent out six times a year. To sign up for Newsletters and other alerts via e-mail, visit http://news.bmn.com/alerts
Biocatalysis and biotransformation Bioinorganic chemistry Web alert Grace R Nakayama A selection of World Wide Web sites relevant to papers published in this issue of Current Opinion in Chemical Biology. Current Opinion in Chemical Biology 2002, 6:121–122 Addresses Pfizer Global Research and Development, La Jolla Laboratories, 10770 Science Center Drive, San Diego, CA 92121 USA; e-mail: [email protected]
Introduction to Biotransformation http://www.sci.tamucc.edu/pals/moslen/garvish/ Biotransformation: species differences and determining factors http://www.sci.tamucc.edu/pals/moslen/dominski/sld001.htm These lecture notes cover topics in biotransformation. They were prepared by John F Garvish and Tammy Domanski, respectively, at Texas A&M University, Corpus Christi (USA).
Biocatalysis and biotransformation
Bioinorganic chemistry
Biocatalysis http://www.nature.com/nature/insights/6817.html Several review articles about biocatalysis appeared in this issue of Nature Insight, which was published in 2001. These articles are available for free to subscribers of Nature or can be purchased individually.
Metalloprotein Site Database and Browser http://metallo.scripps.edu/ The Metalloprotein Site Database and Browser (MDB) compiles information from the Protein Data Bank (PDB) pertaining to metal-binding sites. This database may be searched by entering queries based on geometric and molecular characteristics. In addition, tools are available to visualize structures and analyze quantitative data. The MDB is part of the Metalloprotein Structure, Bioinformatics and Design Program (http://www.scripps.edu/research/metallo/) at The Scripps Research Institute (USA).
Biocatalysis: chemical and pharmaceutical makers seek more efficient and often cleaner routes to making old and new products http://pubs.acs.org/cen/coverstory/7921/7921biocatalysis.html Making drugs with little bugs http://pubs.acs.org/cen/coverstory/7921/7921biocatalysis2.html Biocatalysis: Japan’s unique perspective http://pubs.acs.org/cen/coverstory/7921/7921biocatalysis3.html Chemical and Engineering News published a special report about biocatalysis in the May 21, 2001 issue. These articles were written by Ann M Thayer, Michael McCoy and Jean-François Tremblay, respectively. CSE Links: Directed Evolution http://www.biols.susx.ac.uk/CSE/Links/directed.html Links about directed in vitro molecular evolution are categorized by background, protein evolution, RNA evolution, commercial, journals, and general. They were compiled by the Centre for the Study of Evolution (CSE) at University of Sussex (UK). ExtremoFiles http://www.ualberta.ca/~csotonyi/extremophiles/index.html http://www.crosswinds.net/~juliuscsotonyi/extremophiles Julius T Csotonyi of the Department of Biological Sciences, University of Alberta (Canada) has compiled a number of resources related to extremophiles. They are organized into the following categories: community, databases, education, encyclopedia, events, images, links and literature. The International Society for Extremophiles http://extremophiles.org/ The mission statement of the International Society for Extremophiles is “to advance for the worldwide benefit of people, the science of extremophiles, particularly, life under extreme environments and its applications to the environment, agriculture and industry”. The fourth international congress, Extremophiles2002, will be held in Naples, Italy in Sept 2002 (http://www.extremophiles2002.it/).
Prion Science Archives http://www.mad-cow.org/00/sci_archive_frame.html For the past five years, the Prion Science Archives have collected information about prions. A large number of resources have been organized by the following topics: human genome project and disease genes, conformational diseases (amyloidoses), prion and doppel genes, prion protein, specific diseases, and general interest. This site is sponsored by of the Sperling Biomedical Foundation and is maintained by Michael Greger. It is part of the Official Mad Cow Disease Home Page (http://www.mad-cow.org/~tom/). The PROMISE Database http://bmbsgi11.leeds.ac.uk/promise/MAIN.html/original UK site http://metallo.scripps.edu/PROMISE/mirror US site PROMISE (PROsthetic groups and Metal Ion SitEs in proteins) is a searchable database containing information about prosthetic groups and ion sites in proteins. Major categories include chlorophyll proteins, copper proteins, diiron-carboxylate proteins, haem proteins, iron–sulphur proteins, mononuclear iron proteins, and molybdopterin-containing proteins. Note: the PROMISE database, which is maintained at the University of Leeds (UK), has not been updated since 1999.
Journals Journal of Inorganic Biochemistry http://www.elsevier.nl/inca/publications/store/5/0/5/7/7/2/ http://www.chemweb.com/library/elsevier/effect/display.exe?jc ode=jib Table of contents and abstracts are available for free. Full text of articles is available for subscribers via ChemWeb.
122
Web alert
Biocatalysis and Biotransformation http://www.tandf.co.uk/journals/titles/10242422.html Table of contents, abstracts and article references are available for free. Full text of articles is available to subscribers.
Journal of Molecular Evolution http://link.springer.de/link/service/journals/00239/index.htm Table of contents and abstracts are available for free. Full text of articles is available for subscribers.
Extremophiles: Life Under Extreme Conditions http://link.springer.de/link/service/journals/00792/ Table of contents, abstracts and sample issue are available for free. Full text of articles is available to subscribers.
Nature Structural Biology http://structbio.nature.com/ Table of contents and abstracts are available for free. Full text of articles is available for subscribers.
Journal of Biological Inorganic Chemistry http://link.springer.de/link/service/journals/00775/index.htm Table of contents and abstracts are available for free. Full text of articles is available for subscribers.
Structure http://www.structure.org/ Table of contents and abstracts are available for free. Full text of articles is available for subscribers or for a per-item fee.
Newsletters — a new service from BioMedNet, Current Opinion and Trends Now available, direct to your e-mail box: FREE e-mail newsletters highlighting the latest developments in rapidly moving fields of research. A team of editors from the Current Opinion and Trends journals have combined to compile the Biopharmaceuticals Newsletter — from monoclonal antibodies and recombinant proteins to regulatory affairs and clinical trials. Each newsletter features news articles from the BioMedNet newsdesk, as well as highlights from the review content of the Current Opinion and Trends journals. Access to full-text journal articles is available through your institution. Newsletters are sent out six times a year. To sign up for Newsletters and other alerts via e-mail, visit http://news.bmn.com/alerts