Biological applications of raman spectroscopy. Vol. 3: resonance raman spectra of heme and metalloproteins

Biological applications of raman spectroscopy. Vol. 3: resonance raman spectra of heme and metalloproteins

356 Rutherford back-scattering), materials and other aspects. The second type comprises 24 short contributions (usually 4-8 pages) dealing with a hos...

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356

Rutherford back-scattering), materials and other aspects. The second type comprises 24 short contributions (usually 4-8 pages) dealing with a host of topics ranging from thermoluminescence to stainless steel analysis and pyrolysis FTIR’of polymers to NaYF, thin films. The presentation is generally acceptable, but some of the figures could be improved, especially where they were originally photographs or computer printouts. One article contains direct reproduction of poster material which is itself a set of photographs (p. 158)) the result being a largely incomprehensible pattern of shades of grey! Another describes the determination of sulphate indirectly by AAS (based on PbSO, precipitation). Hardly earth shattering, and indicative of how widely materials characterization is interpreted in this book. Thomas G. Spiro (Ed.), Biological Applications of Raman Spectroscopy. Vol. 3: Resonance Raman Spectra of Heme and Metalloproteins, Wiley, New York, 1988 (ISBN O-471-81575-6). x+ 565 pp. Price $75.00. This volume comprises twelve chapters dealing mainly with haem proteins, but also with chlorophylls and some non-haem metalloproteins (blue copper proteins, respiratory proteins, metal-tyrosinate proteins and iron-sulphur proteins). There are introductory chapters on resonance Raman spectroscopy of metalloporphyrins, and coordinated ligand vibrations, and separate chapters on various haem proteins, including cytochromes c and P450, haemoglobin and myoglobin, and cytochrome oxidase. Each chapter is authoritatively written, with a high density of information. Alan Wiseman (Ed.), Enzyme Induction, Mutagen Activation and Carcinogen Testing in Yeast, Horwood, Chichester, 1987 (ISBN 0-85312-963-O). 215 pp. Price $28.50. The rapid detection of mutagenic activity and therefore, very commonly, of carcinogenic activity is a continuing challenge to the toxicologist. This book describes how one organism, yeast, is being used for this purpose. As the tests are based on genotoxicity, three chapters describe basic aspects of genetic systems, gene induction and repression, and DNA repair and mutagenesis in Saccharomyces cerevisiae. A further chapter describes how cytochrome P-448 enzymes activate mutagens, and the final chapter describes the various tests for mutagens in yeast. The book concludes with an excellent index. This area of toxicological testing is obviously growing quickly, and this is a very competent and timely account of one aspect of it. P.J. Lloyd (Ed.), Particle Size Analysis 1988, Wiley, Chichester, O-471-91997-7). ix+361 pp. Price g45.00.

1988 (ISBN