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Biological markers of Alzheimer's disease
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Biological Markers of Alzheimer's Disease, by F. Boiler, R. K a t z m a n , A. R a s c o l , J . L . S i g n o r e t a n d Y. C h r i s t e n (Eds.), Springer-Verlag, B e r l i n - H e i d e l b e r g - N e w Y o r k , 1989, 175 pages, D M 108.00 ( h a r d cover). This monograph contains the Proceedings of the Toulouse Symposium, April 1989, the 4th of a series started by the Colloques M~decine et Recherche in 1987. The 17 chapters cover cerebrospinal fluid markers, the Tau proteins, MAP 2 and paired helical f'dament epitopes in microgiia and macrophages, followed by an expos6 of the relationship between the protein changes and dementia, the amyloid-fl-precursor and its gene, the amyloid gene on the long arm of chromosome 21, and finally a review of calcium and the cytoskeleton, the use of fibroblast culture and giycolytic enzymes. The 160 pages provide an up-to-date panorama of actual problems at the Alzheimer research frontier, and constitute rewarding reading for the clinical and basic neuroscientist with special interest in the field. The lay-out is of this publisher's well-known standard and the price is reasonable. G.W. B RUYN
Imagerie Anatomique des Nerfs Crdniens, mdthode d'investigation pour l'imagerie par r~sonance magn~tique (IRM) et la tomodensitom~trie (CT), by A. L e b l a n c (Ed.), Springer-Verlag, B e r l i n - H e i d e l b e r g - N e w Y o r k , 1989, 277 pages, 274 illustrations, h a r d c o v e r D M 540.00. This highly original, lavishly executed and colour-illustrated monograph provides a wealth of neuroanatomical detail on each of the 12 cranial nerves to the neuroradiologist (and the neurologist) whose daily diagnostic work today includes the study of CT and NMR procedures. The contents matter is presented in a systematic and most educative fashion, showing the points of the vulnerability along the entire length of each of the cranial nerves, normal asymmetries, the various lesions, the syndromes indicating to the neuroradiologist the site to focus on, etc. This monograph, the result of 15 years of study, radiological and anatomical, is a unique guide in the teamwork of clinical neurologist and neuroradiologist for the rational and efficient diagnosis in cases of neuralgia, nerve tumors, fractures, etc., based upon essentially simple procedures. Unreservedly recommended. The price, of necessity high as a result of the numerous colour pictures, may form an obstacle, but is reasonable nevertheless. G.W. BRUYN
Regulatory Mechanisms of Neuron to Vessel Communication in the Brain, by F. Battani, S. G o v o n i , M . S. M a g n o n i a n d M. T r a b u c c h i (Eds.), NA TO A SI Series H: Cell Biology, Number 33. Springer-Verlag, B e r l i n - H e i d e l b e r g - N e w York, 1989, 416 pages, D M 188.00 This book contains the proceedings of a high-quality workshop held in Salo, Italy, in September 1988. The overall content is of very good quality, offering excellent reviews focused on four main topics: interacting mechanisms involved in the regulation of brain microcirculation; the use of imaging techniques for studying cerebral hemodynamics and metabolic activities; the interplay between neurons, glial cells and blood vessels; neuronal versus vascular approaches in the pharmacological treatment of cerebrovascular disorders. The various chapters are written by experts in the field both from the basic and more clinically oriented areas. This volume provides a reliable and quick state-of-the-art reference. I can recommend it to scientists who are interested in or involved with cerebrovascular research in the broadest sense. M.D. FERRARI
Biological Markers of Alzheimer's Disease, by F. Boiler, R. K a t z m a n , A. R a s c o l , J . L . S i g n o r e t a n d Y. C h r i s t e n (Eds.), Springer-Verlag, B e r l i n - H e i d e l b e r g - N e w Y o r k , 1989, 175 pages, D M 108.00 ( h a r d cover). This monograph contains the Proceedings of the Toulouse Symposium, April 1989, the 4th of a series started by the Colloques M~decine et Recherche in 1987. The 17 chapters cover cerebrospinal fluid markers, the Tau proteins, MAP 2 and paired helical f'dament epitopes in microgiia and macrophages, followed by an expos6 of the relationship between the protein changes and dementia, the amyloid-fl-precursor and its gene, the amyloid gene on the long arm of chromosome 21, and finally a review of calcium and the cytoskeleton, the use of fibroblast culture and giycolytic enzymes. The 160 pages provide an up-to-date panorama of actual problems at the Alzheimer research frontier, and constitute rewarding reading for the clinical and basic neuroscientist with special interest in the field. The lay-out is of this publisher's well-known standard and the price is reasonable. G.W. B RUYN
Imagerie Anatomique des Nerfs Crdniens, mdthode d'investigation pour l'imagerie par r~sonance magn~tique (IRM) et la tomodensitom~trie (CT), by A. L e b l a n c (Ed.), Springer-Verlag, B e r l i n - H e i d e l b e r g - N e w Y o r k , 1989, 277 pages, 274 illustrations, h a r d c o v e r D M 540.00. This highly original, lavishly executed and colour-illustrated monograph provides a wealth of neuroanatomical detail on each of the 12 cranial nerves to the neuroradiologist (and the neurologist) whose daily diagnostic work today includes the study of CT and NMR procedures. The contents matter is presented in a systematic and most educative fashion, showing the points of the vulnerability along the entire length of each of the cranial nerves, normal asymmetries, the various lesions, the syndromes indicating to the neuroradiologist the site to focus on, etc. This monograph, the result of 15 years of study, radiological and anatomical, is a unique guide in the teamwork of clinical neurologist and neuroradiologist for the rational and efficient diagnosis in cases of neuralgia, nerve tumors, fractures, etc., based upon essentially simple procedures. Unreservedly recommended. The price, of necessity high as a result of the numerous colour pictures, may form an obstacle, but is reasonable nevertheless. G.W. BRUYN
Regulatory Mechanisms of Neuron to Vessel Communication in the Brain, by F. Battani, S. G o v o n i , M . S. M a g n o n i a n d M. T r a b u c c h i (Eds.), NA TO A SI Series H: Cell Biology, Number 33. Springer-Verlag, B e r l i n - H e i d e l b e r g - N e w York, 1989, 416 pages, D M 188.00 This book contains the proceedings of a high-quality workshop held in Salo, Italy, in September 1988. The overall content is of very good quality, offering excellent reviews focused on four main topics: interacting mechanisms involved in the regulation of brain microcirculation; the use of imaging techniques for studying cerebral hemodynamics and metabolic activities; the interplay between neurons, glial cells and blood vessels; neuronal versus vascular approaches in the pharmacological treatment of cerebrovascular disorders. The various chapters are written by experts in the field both from the basic and more clinically oriented areas. This volume provides a reliable and quick state-of-the-art reference. I can recommend it to scientists who are interested in or involved with cerebrovascular research in the broadest sense. M.D. FERRARI