Biomaterials and Bioengineering Handbookedited by Donald L. Wise, 920 pp, Marcel Dekker, New York, 2000, ISBN: 0-8247-0318-9,

Biomaterials and Bioengineering Handbookedited by Donald L. Wise, 920 pp, Marcel Dekker, New York, 2000, ISBN: 0-8247-0318-9,

Journal of Controlled Release 75 (2001) 225–229 www.elsevier.com / locate / jconrel Book reviews Protein Formulation and Delivery E.J. McNally, edito...

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Journal of Controlled Release 75 (2001) 225–229 www.elsevier.com / locate / jconrel

Book reviews Protein Formulation and Delivery E.J. McNally, editor, M. Dekker, New York, 2000, 262 pages. and R.E. Reid, editor, Peptide and Protein Analysis, M. Dekker, New York, 2000, 885 pages. We received these two books that address various aspects of protein formulation and analysis. Both books are very well written and will become widely cited monographs in the field. I am particularly impressed by the coverage of Reid’s book which must be a ‘must read’ for all pharmaceutical and biomedical scientists who work in the field of protein delivery. The chapters on chemical synthesis of peptides and proteins, on combinatorial chemistry, bioinformatics, protein sequencing and pharmacogenomics are exceptionally well written. McNally’s book is the more ‘practical’ of the two. Both are well printed with numerous references (especially Reid’s book). Highly recommended. Nicholas A. Peppas Showalter Distinguished Professor of Chemical and Biomedical Engineering Purdue University West Lafayette, IN USA PII: S0168-3659( 01 )00387-X

Biomaterials and Bioengineering Handbook, edited by Donald L. Wise, 920 pp, Marcel Dekker, New York, 2000, ISBN: 0-8247-0318-9 This comprehensive reference handbook provides an update and condensed review on biomaterials in

use in the human body as hard tissue substitutes and drug carriers. It is a book edited by Dan Wise who already enriched us with a master work: Encyclopedia Handbook of Biomaterials and Bioengineering, a series of four books, published five years ago. The book is organized in nine parts and 41 chapters, written by over 150 international experts in each reviewed area. The book contains over 3800 references, and over 400 tables, schemes and pictures which illustrate and help us to get a better understanding about the issues discussed in each chapter. The book covers a wide range of biomaterials from polymers to metals and ceramics. The first two parts focus on the issues of biocompatibility, biodegradation, in vivo and in vitro evaluation methods of compatibility and blood-biomaterial interactions. The third part provides a few unrelated chapters on drug delivery systems followed by part IV containing six chapters on ceramics and carbon based materials for orthopedic applications. Parts V and VI are dedicated to absorbable devices for orthopedic fixation and reconstruction of body defects with chapters on cartilage tissue engineering, bone graft substitution, and absorbable polymers for craniofacial reconstruction. The seventh part discusses collagen based biomaterials with chapters on stabilization of collagen for medical devices, immunology issues and collagen scaffolds for tissue recognition. The following three chapters provide some insights on biomaterials for skin applications and the last part of the book is a collection of four chapters on diverse subjects, including shape memory alloys, chitin derivatives, bioactive hydroxamic acid compounds and fibrin bioadhesives. The category of ‘Handbook’ given to this book is not quite clear as many chapters are of specific interest and do not combine into an integrated

0168-3659 / 01 / $ – see front matter  2001 Published by Elsevier Science B.V.

Book reviews / Journal of Controlled Release 75 (2001) 225 – 229

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sequence of chapters of a cohesive single format that should build a Handbook. Overall, the book contains a valuable collection of chapters that provide a good overview of the field and the diversity of the activities in the area. The book should be available in science, medical, and engineering libraries and on the bookshelves of research groups in the field of biomaterial, biomedical and chemical engineers, biopolymer chemists, and researchers involved with the development of medical devices, drug delivery systems, and biomaterials. It may well serve graduate students and teachers seeking for update information on the relevant topics summarized in this book.

Avi Domb The Hebrew University of Jerusalem School of Pharmacy-Faculty of Medicine Jerusalem 91120 Israel PII: S0168-3659( 01 )00381-9

thought about using drug targeting should get this book. It’s actually available on Amazon.com with delivery in 24 hours. For those who would like some details, the ‘‘strategies’’ discussed include: chemical construction of immunotoxins, RNA-antibody conjugates, bispecific antibodies, active targeting of liposomes, folate as a targeting device and RNase single-chain antibody fusion proteins. The theoretical aspects, which might actually be the best section to read first, include exploitation of passive targeting, uptake of antibodies, and inhibition of tumor blood flow. The final section addresses specific disease states with strategies to treat these using targeted delivery: myocardial infarction, HIV-infected cells, leukemia, lymphoma, and murine malaria. There is also a chapter on immunotargeting of catalase to the pulmonary vascular endothelium to augment antioxidative defense and a final look to the future in targeted gene transfer. However, even in gene transfer the authors provide a detailed experimental protocol for everything from plasmid preparation to liposome preparation to analysis of cell delivery. Anyway you look at it, this is an impressive book.

Lisa Brannon-Peppas Biogel Technology, Inc. Indianapolis, IN USA Drug Targeting: Strategies, Principles and Applications, G.E. Francis and C. Delgado (editors), Humana Press, 2000, $89.50, ISBN: 0-896-03531-X, 320 pp. In a field as new as drug targeting, one would expect a book on the subject to be filled with theory and academic research efforts. This reviewer was very pleased to see that this was not the case for this incredibly interesting and helpful volume. Of course, there is some theory and information presented about targeting and future opportunities, especially in gene transfer. However, this multi-authored book contains (as correctly claimed) detailed, easy-to-follow experimental protocols to prepare targeted delivery systems! Anyone reading this review who has even

PII: S0168-3659( 01 )00382-0

Cell encapsulation technology and therapeutics, ¨ Willem M. Kuhtreiber, Robert P. Lanza, William L. ¨ Chick (Eds.). Birkhauser, Boston, Basel, Berlin, 1999, $195.00 The idea of encapsulating cells was first proposed almost 40 years ago, especially for the immunoprotection of transplanted islet cells. The early procedures used a method that is still favored today,