- Email: [email protected]
Biopsychosocial conditions related with the affective disorders onset in adolescence
S164
IACAPAP 2012 – 20th World congress / Neuropsychiatrie de l’enfance et de l’adolescence 60S (2012) S140–S196
The Child-Behavior-Check-List (CBCL) allows an adequate examination in its sub-scales and in the correlation with clinical symptoms to complement the accuracy of clinical diagnosis for the severe dysregulated child. This research is based on a sample of 113 patients (6–16 years old) referred for their self-regulatory problems. Clinical interviews were conducted and the CBCL-parent was completed. Family history of psychiatric disorders, traumatic events and characteristics of thyroid profile were analyzed. Results.– The children referred for their severe Dysregulated-behavior: Mean Total Problems (TP) 75.8 and 90% with Total competence score below T < 37 (< 10th percentile), were classified into 4 groups: Bipolar Pediatric Spectrum 41.2%, Emotionally Dysregulated (affective, behavior and cognitive regulation) 32.5%, severe ADHD 17.5%, Conduct Disorder (CD) 8.8%. There are significant differences in Mean TP between these groups. Subscales CBCL-DP and CBCL-PSTP have significant Pearson correlation (0.815). There is a significant correlation (P = 0.001) of both subscales with clinical diagnosis of BP-spectrum and Emotional-Dysregulation. Conclusions.– The proposed scale CBCL-DSS (Dysregulation-Short-Scale) appears to be useful in identifying patients with emotional-dysregulation, discriminating those patients with CD or severe ADHD. http://dx.doi.org/10.1016/j.neurenf.2012.04.222 Mo-P-1111
Are attachment and developmental trauma factors considered in the paediatric bipolar disorder literature? P.I. Parry Nundah CYMHS, Nundah, Brisbane, Australia Paediatric bipolar disorder (PBD) continues to attract controversy as to the validity of the construct. One main critique is that PBD has arisen from a neglect in psychiatric nosology of attachment insecurity and developmental trauma. To test this criticism, a systematic literature review of the PBD literature via a Scopus search found 7,257 articles from January 1995 to June 2010. An “All Fields” search (title, abstract, keywords, citation titles) for the words attachment, trauma, PTSD, abuse, maltreatment suggested these concepts received limited consideration. A full text search of articles from the two institutions that pioneered the PBD diagnostic constructs confirmed a virtual absence of mention of attachment theory. Developmental trauma, maltreatment and PTSD received limited coverage but were described by researchers associated with the “broad phenotype” PBD construct as likely secondary to PBD. A comparison of neuroimaging studies from attachment/developmental traumatology and PBD research showed similar findings interpreted differently. A developmental traumatology perspective may help resolve the controversy over PBD. http://dx.doi.org/10.1016/j.neurenf.2012.04.223 Mo-P-1112
Diagnostic problems of juvenile-onset bipolar disorder which is comorbid with attention-deficit hyperactivity disorder (ADHD) A. Okada a,∗ , J. Matuo a , N. Tsujii b , R. Kaku c Psychiatry, Nara Hospital Kinki University School of Medicine, Ikoma City, Japan b Psychiatry, Kinnki University School of Medicine, Osakasayama City, Japan c Sociology, St. Andrew’s University, Izumi City, Japan ∗ Corresponding author.
a
Objective.– To investigate diagnostic problems of juvenile-onset bipolar disorder which was comorbid with ADHD in a prospective clinical study. Method.– The study sample was six children who were derived from 32 outpatients ages 6–8 years referred for ADHD to our outpatient department during one year from 2008. They were assessed using Kiddlie-Sads-Present and Lifetime version (K-SADS-PL) and were diagnosed with bipolar disorder not otherwise specified as well as ADHD by DSM-IV-TR criteria. We assessed symptoms of mania and depressive disorders of K-SADS-PL,
behavioral problems, and other symptoms once every two months at least for three years. Results.– In three cases, these clinical manifestations were repeatedly present. Two cases of them progressed to meet the DSM-IV-TR criteria for BP-II. In the other three cases, elation, increased aggression and temper tantrum improved after adjustment of surrounding environments within one year and were not present during the period of the study. Conclusion.– The findings suggest that manic symptoms need to be assessed over time for diagnosis of bipolar disorder. During long clinical course, cycle of elation may be helpful diagnostic cue. http://dx.doi.org/10.1016/j.neurenf.2012.04.224 Mo-P-1113
Aripiprazole monotherapy for pediatric bipolar disorder in Korea: A retrospective chart review K. Cheon a,∗ , J. Oh b , K. Jhung b , D. Song b Child and Adolescent Psychiatry, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea b Department of Child and Adolescent Psychiatry, Yonsei University College of Medicine, Seoul, Korea ∗ Corresponding author.
a
The present study is a retrospective chart review investigating the effect and tolerability of aripiprazole compared to other atypical antipsychotics in children and adolescents with bipolar disorder. Among the 127 youths with bipolar disorder who had been treated with atypical antipsychotics alone, there were 62 patients (48.8%) treated with aripiprazole (mean daily dose = 9.6 ± 5.4 mg), 52 (40.9%) with risperidone (1.5 ± 1.1 mg), 11 (8.7%) with quetiapine (207.5 ± 200.5 mg), and 2 (1.6%) with paliperidone (4.5 ± 2.1 mg). The mean duration of treatment was 7.8 ± 5.3 months. Those treated with aripiprazole showed lower Clinical Global impression (CGI)-Severity scores at their second, third and last visit as well as lower CGI-Improvement scores at the second and last visit compared to those treated with other antipsychotics. Treatment with atypical antipsychotics alone was well tolerated. This study confirms the effectiveness and tolerability of atypical antipsychotic monotherapy and supports the possible benefits of using aripiprazole in pediatric bipolar disorders. http://dx.doi.org/10.1016/j.neurenf.2012.04.225 Mo-P-1114
Manic episode after termination of epilepsy treatment: A case report B. Ersoz Alan a,∗ , D. Unal b Child and Adolescent Psychiatry, Dr. Sami Ulus Childrens’ Hospital, Ankara, Turkey b Child And Adolescent Psychiatry, Hacettepe University Ihsan ˙ Dogramaci Childrens’ Hospital, Ankara, Turkey ∗ Corresponding author.
a
Epilepsy and Bipolar Disorder (BD) are two of the episodic and chronic neuropsyhiatric disorders and although Antiepileptic Drugs (AEDs) are used as the first-line treatment for BD and epilepsy; it is unclear whether AEDs could prevent symptoms of BD in epilepsy. We here introduce a 16-year-old mentally retarded girl, who had been treated with an AED, carbamazepine (CMZ), for partial epilepsy. She had her first manic episode just after the termination of CMZ treatment. Manic symptoms were resolved with a combination of CMZ and risperidone. Psychiatrists should be aware of such presentations of BD as mood symptoms are common in epilepsy and BD has a high risk for functional impairment. http://dx.doi.org/10.1016/j.neurenf.2012.04.226 Mo-P-1116
Biopsychosocial conditions related with the affective disorders onset in adolescence S.C. Macovei a,∗ , C. Trutescu b Psychiatry, Bucharest, Romania
a
IACAPAP 2012 – 20th World congress / Neuropsychiatrie de l’enfance et de l’adolescence 60S (2012) S140–S196 b
Child and Adolescent Psychiatry, Bucharest, Romania author.
∗ Corresponding
Introduction.– The onset of affective disorders can be difficult to recognize, often the onset of this disorders takes place slowly, looking like other psychiatric disorders. Symptoms like expansiveness, logorrhea, lack of inhibition, concentration difficulties, may cause a clinical picture suggestive for conduct disorder or hyperkinetic disorders, and later the symptomatology will became more conclusive for an affective disorder. Objectives.– This paper aims to identify the most common ways of onset of affective disorders in children and adolescents. Method.– We conducted a retrospective analysis on a sample of 56 adolescents diagnosed with an affective disorder. The data obtained were statistically interpreted. Results.– ADHD is the most common mental disorder found in the psychiatric history of children who develop psychosis, followed in order of frequency by Conduct Disorder, Asperger Syndrome and Suicide Attempts. It was observed a high frequency of a history of preterm birth in those children who had a history of ADHD. http://dx.doi.org/10.1016/j.neurenf.2012.04.228 Mo-P-1117
Neuropsychologic profiles of adolescents diagnosed with bipolar affective disorder (BAD) and with high risk of BAD K. Karabekiroglu a,∗ , M.N. Karakurt b , M. Yüce a , T. C ¸ alik a Child and Adolescent Psychiatry, Ondokuz Mayis University Medical Faculty, Samsun, Turkey b Child and Adolescent Psychiatry, Diyarbakır Child Hospital, Diyarbakır, Turkey ∗ Corresponding author.
a
The aim of this study was to determine clinical and neuropsychological features associated with Bipolar Affective Disorder (BAD) in adolescence and assessing clinical and neuropsychological parameters of the high-risk adolescents in terms of familial transmission of BAD and determine probable early markers for the disorder. The study includes 12- to 18-year-old 25 cases diagnosed with BAD (study group), 25 adolescents whose parent or sibling previously diagnosed with BAD and the adolescent had no mood disorder (risk group) and typically growing 25 adolescents (control group). According to results, when compared with healthy controls, adolescents with BAD showed statistically significant worse performance in Wisconsin Card Sorting Test (WCST), Stroop Test and Continuous Performance Test (CPT) in terms of executive and attention functions, whereas there was no difference with risk group. In addition, adolescents in both study and risk groups reported significantly more clinical and behavioral problems compared to control cases. Our findings suggest that; disorder itself may be associated with attention and executive function impairments, while the familial risk for BAD may be associated with some behavioural problems. http://dx.doi.org/10.1016/j.neurenf.2012.04.229 Mo-P-1118
Parents’ estimates of quality of life of children with specific developmental language disorders M. Vlassopoulos , V. Rotsika ∗ , M. Ginieri-Coccossis A’ Psychiatric Clinic, Medical School, University of Athens, Athens, Greece Keywords: Specific Developmental Language Disorders; Quality of life; Preschool children ∗ Corresponding author. Introduction.– The impact of specific developmental language disorder (SDLD) on the quality of life (QoL) of the children, as well as their parents is of primary importance when planning the intervention and the rehabilitation of these individuals. Nevertheless, although QoL has been studied in several pathological groups, it has not been studied adequately in language disordered children and their families. In this study, the quality of life of parents of children with SDLD, as well as their estimate of that of their children is investigated. Furthermore, possible associations are explored between parental and child QoL.
S165
Methods.– The experimental group consisted of 65 participants, who were one of two parents of preschool children who had been diagnosed with SDLD according to ICD-10 criteria. The control group consisted of 489 parents of typically developing children. Parents completed the WHOQOL-BREF questionnaire, a measure developed by the World Health Organisation to assess QoL in adults, and the KINDLR questionnaire for their children (4–7 years). The specific dimensions of the WHOQOL explore health, emotional well-being, social relationships and environmental aspects, while the KINDLR investigates health, emotional well-being, self-esteem, family, friends and school functioning. Results.– The parents of children with SDLD report lower QoL measures for themselves in general, as well as in several specific dimensions. Regarding their children, they estimate that their children were experiencing poorer emotional well-being and deficits in social functioning. The quality of social relationships of the parents is a significant predictor of the child’s family, friends and school functioning. Conclusions.– Although the children in our study were in the preschool age group, their parents are already reporting significant difficulties in several dimensions of their quality of life. It therefore appears that SDLD has a strong impact on both the quality of life of these children, as well as on their families. It is recommended that family-centred programmes actively promote the quality of life of these families, which in turn will interact with the therapeutic measures provided for the child. http://dx.doi.org/10.1016/j.neurenf.2012.04.230 Mo-P-1119
The speech processing deficits in Mandarin-speaking school-aged children with specific language impairment H. Liu a,∗ , F. Tsao b , L. Chen c Department of Special Education, National Taiwan Normal University, Taipei, Taiwan b Psychology, National Taiwan University, Taipei, Taiwan c Special Education, Taipei Municipal Da-An Elementary School, Taipei, Taiwan ∗ Corresponding author.
a
This study aimed to examine the speech processing ability of Mandarin-speaking school-aged children with specific language impairment (SLI). Speech processing deficits were reported in English-speaking children, but few studies examined the speech processing ability in children with SLI learning a tonal language (e.g. Mandarin Chinese). Twenty 8- to 10-year-old children with SLI and 20 age/IQ-matched children were recruited. The computerized speech perception and auditory processing tests along with the standardized intelligence and language assessments were utilized. Compared to the control group, children with SLI performed significantly poorer on frequency discrimination, consonant discrimination, and the Mandarin lexical tone discrimination tasks. Both deficits in auditory and speech processing were exhibited in children with SLI and these might negatively influence their language development. The speech perception was significantly correlated with language abilities, and the regression analysis revealed that the accuracy of lexical tone discrimination was the best predictor of the language ability. http://dx.doi.org/10.1016/j.neurenf.2012.04.231 Mo-P-1120
Implication of working memory and executive functions in comprehension of idioms by patients with schizophrenia A. Lacroix a,∗ , A. Noël a , M. Guillery a , T. Dondaine b , V. Laval c EA 1285, centre de recherches en psychologie, cognition et communication, université européenne de Bretagne, université Rennes 2, Rennes, France b EA, CHU de Rennes, Rennes, France c UMR CNRS 6234, centre de recherches sur la cognition et l’apprentissage (CERCA), université de Poitiers, Poitiers, France ∗ Corresponding author.
a
The aim of this study is to investigate the idioms comprehension in patients with schizophrenia and the role of working memory and executive functions in this comprehension. Nine patients with schizophrenia aged between 26 and 46
IACAPAP 2012 – 20th World congress / Neuropsychiatrie de l’enfance et de l’adolescence 60S (2012) S140–S196
The Child-Behavior-Check-List (CBCL) allows an adequate examination in its sub-scales and in the correlation with clinical symptoms to complement the accuracy of clinical diagnosis for the severe dysregulated child. This research is based on a sample of 113 patients (6–16 years old) referred for their self-regulatory problems. Clinical interviews were conducted and the CBCL-parent was completed. Family history of psychiatric disorders, traumatic events and characteristics of thyroid profile were analyzed. Results.– The children referred for their severe Dysregulated-behavior: Mean Total Problems (TP) 75.8 and 90% with Total competence score below T < 37 (< 10th percentile), were classified into 4 groups: Bipolar Pediatric Spectrum 41.2%, Emotionally Dysregulated (affective, behavior and cognitive regulation) 32.5%, severe ADHD 17.5%, Conduct Disorder (CD) 8.8%. There are significant differences in Mean TP between these groups. Subscales CBCL-DP and CBCL-PSTP have significant Pearson correlation (0.815). There is a significant correlation (P = 0.001) of both subscales with clinical diagnosis of BP-spectrum and Emotional-Dysregulation. Conclusions.– The proposed scale CBCL-DSS (Dysregulation-Short-Scale) appears to be useful in identifying patients with emotional-dysregulation, discriminating those patients with CD or severe ADHD. http://dx.doi.org/10.1016/j.neurenf.2012.04.222 Mo-P-1111
Are attachment and developmental trauma factors considered in the paediatric bipolar disorder literature? P.I. Parry Nundah CYMHS, Nundah, Brisbane, Australia Paediatric bipolar disorder (PBD) continues to attract controversy as to the validity of the construct. One main critique is that PBD has arisen from a neglect in psychiatric nosology of attachment insecurity and developmental trauma. To test this criticism, a systematic literature review of the PBD literature via a Scopus search found 7,257 articles from January 1995 to June 2010. An “All Fields” search (title, abstract, keywords, citation titles) for the words attachment, trauma, PTSD, abuse, maltreatment suggested these concepts received limited consideration. A full text search of articles from the two institutions that pioneered the PBD diagnostic constructs confirmed a virtual absence of mention of attachment theory. Developmental trauma, maltreatment and PTSD received limited coverage but were described by researchers associated with the “broad phenotype” PBD construct as likely secondary to PBD. A comparison of neuroimaging studies from attachment/developmental traumatology and PBD research showed similar findings interpreted differently. A developmental traumatology perspective may help resolve the controversy over PBD. http://dx.doi.org/10.1016/j.neurenf.2012.04.223 Mo-P-1112
Diagnostic problems of juvenile-onset bipolar disorder which is comorbid with attention-deficit hyperactivity disorder (ADHD) A. Okada a,∗ , J. Matuo a , N. Tsujii b , R. Kaku c Psychiatry, Nara Hospital Kinki University School of Medicine, Ikoma City, Japan b Psychiatry, Kinnki University School of Medicine, Osakasayama City, Japan c Sociology, St. Andrew’s University, Izumi City, Japan ∗ Corresponding author.
a
Objective.– To investigate diagnostic problems of juvenile-onset bipolar disorder which was comorbid with ADHD in a prospective clinical study. Method.– The study sample was six children who were derived from 32 outpatients ages 6–8 years referred for ADHD to our outpatient department during one year from 2008. They were assessed using Kiddlie-Sads-Present and Lifetime version (K-SADS-PL) and were diagnosed with bipolar disorder not otherwise specified as well as ADHD by DSM-IV-TR criteria. We assessed symptoms of mania and depressive disorders of K-SADS-PL,
behavioral problems, and other symptoms once every two months at least for three years. Results.– In three cases, these clinical manifestations were repeatedly present. Two cases of them progressed to meet the DSM-IV-TR criteria for BP-II. In the other three cases, elation, increased aggression and temper tantrum improved after adjustment of surrounding environments within one year and were not present during the period of the study. Conclusion.– The findings suggest that manic symptoms need to be assessed over time for diagnosis of bipolar disorder. During long clinical course, cycle of elation may be helpful diagnostic cue. http://dx.doi.org/10.1016/j.neurenf.2012.04.224 Mo-P-1113
Aripiprazole monotherapy for pediatric bipolar disorder in Korea: A retrospective chart review K. Cheon a,∗ , J. Oh b , K. Jhung b , D. Song b Child and Adolescent Psychiatry, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea b Department of Child and Adolescent Psychiatry, Yonsei University College of Medicine, Seoul, Korea ∗ Corresponding author.
a
The present study is a retrospective chart review investigating the effect and tolerability of aripiprazole compared to other atypical antipsychotics in children and adolescents with bipolar disorder. Among the 127 youths with bipolar disorder who had been treated with atypical antipsychotics alone, there were 62 patients (48.8%) treated with aripiprazole (mean daily dose = 9.6 ± 5.4 mg), 52 (40.9%) with risperidone (1.5 ± 1.1 mg), 11 (8.7%) with quetiapine (207.5 ± 200.5 mg), and 2 (1.6%) with paliperidone (4.5 ± 2.1 mg). The mean duration of treatment was 7.8 ± 5.3 months. Those treated with aripiprazole showed lower Clinical Global impression (CGI)-Severity scores at their second, third and last visit as well as lower CGI-Improvement scores at the second and last visit compared to those treated with other antipsychotics. Treatment with atypical antipsychotics alone was well tolerated. This study confirms the effectiveness and tolerability of atypical antipsychotic monotherapy and supports the possible benefits of using aripiprazole in pediatric bipolar disorders. http://dx.doi.org/10.1016/j.neurenf.2012.04.225 Mo-P-1114
Manic episode after termination of epilepsy treatment: A case report B. Ersoz Alan a,∗ , D. Unal b Child and Adolescent Psychiatry, Dr. Sami Ulus Childrens’ Hospital, Ankara, Turkey b Child And Adolescent Psychiatry, Hacettepe University Ihsan ˙ Dogramaci Childrens’ Hospital, Ankara, Turkey ∗ Corresponding author.
a
Epilepsy and Bipolar Disorder (BD) are two of the episodic and chronic neuropsyhiatric disorders and although Antiepileptic Drugs (AEDs) are used as the first-line treatment for BD and epilepsy; it is unclear whether AEDs could prevent symptoms of BD in epilepsy. We here introduce a 16-year-old mentally retarded girl, who had been treated with an AED, carbamazepine (CMZ), for partial epilepsy. She had her first manic episode just after the termination of CMZ treatment. Manic symptoms were resolved with a combination of CMZ and risperidone. Psychiatrists should be aware of such presentations of BD as mood symptoms are common in epilepsy and BD has a high risk for functional impairment. http://dx.doi.org/10.1016/j.neurenf.2012.04.226 Mo-P-1116
Biopsychosocial conditions related with the affective disorders onset in adolescence S.C. Macovei a,∗ , C. Trutescu b Psychiatry, Bucharest, Romania
a
IACAPAP 2012 – 20th World congress / Neuropsychiatrie de l’enfance et de l’adolescence 60S (2012) S140–S196 b
Child and Adolescent Psychiatry, Bucharest, Romania author.
∗ Corresponding
Introduction.– The onset of affective disorders can be difficult to recognize, often the onset of this disorders takes place slowly, looking like other psychiatric disorders. Symptoms like expansiveness, logorrhea, lack of inhibition, concentration difficulties, may cause a clinical picture suggestive for conduct disorder or hyperkinetic disorders, and later the symptomatology will became more conclusive for an affective disorder. Objectives.– This paper aims to identify the most common ways of onset of affective disorders in children and adolescents. Method.– We conducted a retrospective analysis on a sample of 56 adolescents diagnosed with an affective disorder. The data obtained were statistically interpreted. Results.– ADHD is the most common mental disorder found in the psychiatric history of children who develop psychosis, followed in order of frequency by Conduct Disorder, Asperger Syndrome and Suicide Attempts. It was observed a high frequency of a history of preterm birth in those children who had a history of ADHD. http://dx.doi.org/10.1016/j.neurenf.2012.04.228 Mo-P-1117
Neuropsychologic profiles of adolescents diagnosed with bipolar affective disorder (BAD) and with high risk of BAD K. Karabekiroglu a,∗ , M.N. Karakurt b , M. Yüce a , T. C ¸ alik a Child and Adolescent Psychiatry, Ondokuz Mayis University Medical Faculty, Samsun, Turkey b Child and Adolescent Psychiatry, Diyarbakır Child Hospital, Diyarbakır, Turkey ∗ Corresponding author.
a
The aim of this study was to determine clinical and neuropsychological features associated with Bipolar Affective Disorder (BAD) in adolescence and assessing clinical and neuropsychological parameters of the high-risk adolescents in terms of familial transmission of BAD and determine probable early markers for the disorder. The study includes 12- to 18-year-old 25 cases diagnosed with BAD (study group), 25 adolescents whose parent or sibling previously diagnosed with BAD and the adolescent had no mood disorder (risk group) and typically growing 25 adolescents (control group). According to results, when compared with healthy controls, adolescents with BAD showed statistically significant worse performance in Wisconsin Card Sorting Test (WCST), Stroop Test and Continuous Performance Test (CPT) in terms of executive and attention functions, whereas there was no difference with risk group. In addition, adolescents in both study and risk groups reported significantly more clinical and behavioral problems compared to control cases. Our findings suggest that; disorder itself may be associated with attention and executive function impairments, while the familial risk for BAD may be associated with some behavioural problems. http://dx.doi.org/10.1016/j.neurenf.2012.04.229 Mo-P-1118
Parents’ estimates of quality of life of children with specific developmental language disorders M. Vlassopoulos , V. Rotsika ∗ , M. Ginieri-Coccossis A’ Psychiatric Clinic, Medical School, University of Athens, Athens, Greece Keywords: Specific Developmental Language Disorders; Quality of life; Preschool children ∗ Corresponding author. Introduction.– The impact of specific developmental language disorder (SDLD) on the quality of life (QoL) of the children, as well as their parents is of primary importance when planning the intervention and the rehabilitation of these individuals. Nevertheless, although QoL has been studied in several pathological groups, it has not been studied adequately in language disordered children and their families. In this study, the quality of life of parents of children with SDLD, as well as their estimate of that of their children is investigated. Furthermore, possible associations are explored between parental and child QoL.
S165
Methods.– The experimental group consisted of 65 participants, who were one of two parents of preschool children who had been diagnosed with SDLD according to ICD-10 criteria. The control group consisted of 489 parents of typically developing children. Parents completed the WHOQOL-BREF questionnaire, a measure developed by the World Health Organisation to assess QoL in adults, and the KINDLR questionnaire for their children (4–7 years). The specific dimensions of the WHOQOL explore health, emotional well-being, social relationships and environmental aspects, while the KINDLR investigates health, emotional well-being, self-esteem, family, friends and school functioning. Results.– The parents of children with SDLD report lower QoL measures for themselves in general, as well as in several specific dimensions. Regarding their children, they estimate that their children were experiencing poorer emotional well-being and deficits in social functioning. The quality of social relationships of the parents is a significant predictor of the child’s family, friends and school functioning. Conclusions.– Although the children in our study were in the preschool age group, their parents are already reporting significant difficulties in several dimensions of their quality of life. It therefore appears that SDLD has a strong impact on both the quality of life of these children, as well as on their families. It is recommended that family-centred programmes actively promote the quality of life of these families, which in turn will interact with the therapeutic measures provided for the child. http://dx.doi.org/10.1016/j.neurenf.2012.04.230 Mo-P-1119
The speech processing deficits in Mandarin-speaking school-aged children with specific language impairment H. Liu a,∗ , F. Tsao b , L. Chen c Department of Special Education, National Taiwan Normal University, Taipei, Taiwan b Psychology, National Taiwan University, Taipei, Taiwan c Special Education, Taipei Municipal Da-An Elementary School, Taipei, Taiwan ∗ Corresponding author.
a
This study aimed to examine the speech processing ability of Mandarin-speaking school-aged children with specific language impairment (SLI). Speech processing deficits were reported in English-speaking children, but few studies examined the speech processing ability in children with SLI learning a tonal language (e.g. Mandarin Chinese). Twenty 8- to 10-year-old children with SLI and 20 age/IQ-matched children were recruited. The computerized speech perception and auditory processing tests along with the standardized intelligence and language assessments were utilized. Compared to the control group, children with SLI performed significantly poorer on frequency discrimination, consonant discrimination, and the Mandarin lexical tone discrimination tasks. Both deficits in auditory and speech processing were exhibited in children with SLI and these might negatively influence their language development. The speech perception was significantly correlated with language abilities, and the regression analysis revealed that the accuracy of lexical tone discrimination was the best predictor of the language ability. http://dx.doi.org/10.1016/j.neurenf.2012.04.231 Mo-P-1120
Implication of working memory and executive functions in comprehension of idioms by patients with schizophrenia A. Lacroix a,∗ , A. Noël a , M. Guillery a , T. Dondaine b , V. Laval c EA 1285, centre de recherches en psychologie, cognition et communication, université européenne de Bretagne, université Rennes 2, Rennes, France b EA, CHU de Rennes, Rennes, France c UMR CNRS 6234, centre de recherches sur la cognition et l’apprentissage (CERCA), université de Poitiers, Poitiers, France ∗ Corresponding author.
a
The aim of this study is to investigate the idioms comprehension in patients with schizophrenia and the role of working memory and executive functions in this comprehension. Nine patients with schizophrenia aged between 26 and 46