- Email: [email protected]
Biosensors 94 — a preview of the third world congress on biosensors
MEETINQPREVIEW
Biosensors & Bioelectronics Vol. 9 No. 2 (1994)
Biosensors 94 - A Preview of the Third World Congress on Biosensors Professor Anthony P.F. Turner, Cranfield Biotechnology Centre, Cranfield University, Cranfield, Bedford MK43 OAL, UK Managers must make hard decisions in these recession-ridden days. Gone are the times when mere interest was sufficient grounds to attend a conference. Unless your presence is essential you are unlikely to succeed in justifying the time and expense involved. Thus the key meetings have expanded and the unfocussed or peripheral gathering has suffered traumatic decline.
N dramatically owhere
has
this decline been more illustrated than in the biosensor business. The proliferation of meetings and symposia of the 80’s has given way to rationalisation; both the audience and presenters have focused their attentions on a single international event, the bi-annual world Congress on Biosensors, to be held this year in New Orleans l-3 June 1994. The question has become not whether to attend, but how many people you can send to cover the intense parallel programme. The World Congress on Biosensors has evolved into the largest and most well represented event of its kind in this field. It is widely recognised as the one venue that can bring you completely up to date with advances in Biosensors during the past two years. At Biosensors ‘94, nearly 300 carefully selected and original presentations from 32 countries will be made to a capacity audience from around 60 countries.
Mini symposium The congress opens with a mini symposium on Commercial Development and Application of Biosensors. The session is launched appropriately by Dr John Hurrel, the Director of Clinical
X
Chemistry R&D from Boehringer Mannheim, USA. His company will field the largest number of submitted papers accepted by the congress from a single organization and will reveal the breadth of their little-publicised R&D programme on biosensors. The principal competitor for Pharmacia’s surface plasmon resonance-based BIAcore instrument range will be discussed by Dr Denise Pollard-Knight in her description of Fisons’ work on the IASys. Dr Graham Davis (i-Stat) will then present the work behind the launch of their 7-channel clinical chemistry chip incorporating biosensors for glucose and urea. Biosensors for clinical analysis and sports medicine produced by MDC, Berlin will be described by Dr Dorothea Pfeiffer. This first plenary session will be completed by a view from the Environmental Protection Agency of the USA(Dr Kay Rogers) on the future of biosensors for environmental monitoring. This final area is the fastest moving application with the promise of rapid commercial reward. Understanding the intricacies of the demands placed on an analytical device to be used in this arena, however, is essential for success.
0956-5663/94/$7.00
0 1994 Elsevier Science Ltd.
Biosensors & Bioelectronics Vol. 9 No. 2 (1994)
Main symposia The afternoon of the first day sees the launch of the three main symposia, which run in parallel through the congress. The session on Enzyme-based Sensors begins with a series of papers on amperometric biosensors, whereas the Affinity Sensors Symposium starts with an optical bias. The environmental theme is continued by many of the initial papers in the third symposium on Whole Cell-based Sensors. A key feature of the afternoon is the interactive poster session which occupies a central position between the two oral sessions. The themes of this first display are Commercial Development and Application of Biosensors, and Enzyme-based Sensors. Posters are again on view during the sponsored evening reception at which the Biosensors and Bioelectronics Journal Award for outstanding service in the field of Biosensor Technology will be presented.
New Orleans New Orleans is synonymous with one of the most prominent founders of the field, Professor Guilbault, who will present the congress plenary lecture “Biosensors: a New Orleans Perspective”. The theme of amperometric biosensors will then be developed by myself followed by Professor Schmidt from Munich, who has consistently delivered some of the most exacting work in the area. The emotive field of neural networks and electrode arrays will be reviewed by Professor Gross (University of North Texas) and the invited section will be completed by Professor Karube, who will present an inspired view of the future that could only be formed within the context of Japan’s long range strategy in the field. The four symposia themes are picked up again in the afternoon and sandwich the second poster discussion featuring Affinity Sensors, Whole Cell-based Biosensors and General Aspects of Biosensors. A spectacular social event follows in the evening aboard the Creole Queen Paddle Wheeler, during which YSI Inc will
UImffi
PRMEW
present the YSI Biosensor Award for Scientific contribution to the advancement of Biosensor Technology.
Optical theme Friday 3 June, has a particularly strong optical theme flowing through the day although electrochemists can take solace in one of the two parallel enzyme-sensor sessions which focuses on amperometry, or in the Affinity Sensor Symposium. Professor Lundstrom (Linkoping) opens the plenary session with a review of his pioneering work on surface plasmon resonance, which has opened up a second major commercial avenue for biosensors following on from successes with enzyme electrodes. The alternative strategy of using fluorescent labels in combination with waveguides had looked like a more viable commercial strategy, but the launch of viable formats has been delayed. Dr Flanagan (University College London) will examine the options for fluorescence immunosensors. Single-stranded DNA is a powerful recognition element, but harnessing its properties in an affinity sensor format offers particular challenges which will be discussed by Professor Thompson from the University of Toronto. Arguably the newest biological sensing element to be considered for inclusion in biosensors is double-stranded DNA. Russia has led the way in this approach an some recent advances will be described by Professor Yevdokimov (Russian Academy of Sciences, Moscow). The invited sessions will close with a presentation on the enabling subject of surface analysis in biosensor design by Professor Gopel (Tubingen). As biosensor technology matures it becomes increasingly apparent that design considerations must be tackled at a molecular level.
Open interaction In addition to the intense scientific programme, the location of the conference in a single sizable
xi
MEEl’iNQ PREVIEW
venue, the New Orleans Hilton Riverside, will facilitate interactions between key industrialists, opinion leaders, scientists and administrators in the area. As a new addition to the Congress there will be a display of commercial equipment so you can catch up on the latest tools of the trade as well as spotting the newest innovations.
Biosensors & Bioelectronics Vol. 9 No. 2 (1994)
Biosensors ‘94 has something for everybody from those interested in environmental monitoring or clinical chemistry to specialists in food safety or biotechnology. A truly multidisciplinary event, it will bring together optical physicists and biochemists, analytical chemists and engineers to realise the exciting commercial opportunity offered by this fast-moving technology.
Analytical laboratory on an optical chip The world renowned CranfieEd Biotechnology Centre and the “British brecealdhroughin integrated opti&, B&&ham TechnoIw Ltd., have joined iT5~a~cses in a DTVSERC LXNK Molecular Sensors Programme. This collaboration brings together the reqtid expertise to successfully exploit silicon integrated optical chemi-biomsors, namely the experience within integrated optics mauufacturiug and sensor technQlogy. The project is entitled: “Silicon-an-Insulator Integrated Optical Sensors: UItrasensitive C%emi/Biosensiug” and aims to provide a low-cost, multi-analyte auaIytical instrument based on silicon integrated optical evanescent field sensing devices. The duration of the project is 1 year and the final results will be released by the end of 1994. The LINK project will draw on the sub&a&al microengineering resources of Bookham’s rented facilities at the Central Microstructure Facility, Rutherford Appleton Laborato~. This co-operation between Bookham Techuology Ltd. and Craufield Biatechuology Centre is only the start of a &XX?business relationship, The combination of Bookham’s and Cranfield% expertise within integrated optics and sensor teclmology respectively w% ensure further innovative de&u and low-cost manufacture, providing a reaI opporttity for industry. Together they wil1cover alI application area within sensor technology, such as ctiuical diagnostics and euviromeutal monitoring aud detection (e.g. pesticides and herbicides in soil and water, hazardous gases and pullutants, including metals, organics, industrial and agricultural waste), food quality and control and industrial fermentation monitoring. Bookham’s input to the co-operation is the Active Silicon Integrated Optical Circuit manufacturing technology (ASOC) which keeps the cost of fibre and integrated optical devices to a minimum, because it utilizes standard silicon electronic circuit mamfacturiug methods. ASOC was developedwith support from the DTI. The ASCKYmanufacturing technology can not ouIy be applied in developing silica sensors, but also covers such application areas as distance measurermnt and fibre opti telecommunications. En January, a oanaurtium ted by Bookham Technology Ltd. received fl m&m to design optical
telewmmunications components for fibre-to-the-home. Cranfield will add to the collaboration more than twelve years uf experience within development ’ and applicatiun of sensors. CraufieId Biotechnology Centre spe&&ses in fabrication technology for mass production of inexpensive devices and conducts both academic and industrial research. CranGeld has a Iarge team of experts whose work is entirely dedicated to sensors and diagnostics. Together Ganfield BiotechnoIogy an&e and Bookham TahuoIugy Ltd. will work towards more rdiable and bwer cost integrated optical sensors and diagnostics system to service all industries need. Conram D&z ?Q~eil, C~IXK$& Bio~&mology Cent. Teitfkx: [4#] (01234 ?5437(v7505ho?. Mette I%&m~ Book&m TecJmotogy I.&. Tel&m: [44] (0123.5445377Y4468.74.
xii
Biosensors & Bioelectronics Vol. 9 No. 2 (1994)
Biosensors 94 - A Preview of the Third World Congress on Biosensors Professor Anthony P.F. Turner, Cranfield Biotechnology Centre, Cranfield University, Cranfield, Bedford MK43 OAL, UK Managers must make hard decisions in these recession-ridden days. Gone are the times when mere interest was sufficient grounds to attend a conference. Unless your presence is essential you are unlikely to succeed in justifying the time and expense involved. Thus the key meetings have expanded and the unfocussed or peripheral gathering has suffered traumatic decline.
N dramatically owhere
has
this decline been more illustrated than in the biosensor business. The proliferation of meetings and symposia of the 80’s has given way to rationalisation; both the audience and presenters have focused their attentions on a single international event, the bi-annual world Congress on Biosensors, to be held this year in New Orleans l-3 June 1994. The question has become not whether to attend, but how many people you can send to cover the intense parallel programme. The World Congress on Biosensors has evolved into the largest and most well represented event of its kind in this field. It is widely recognised as the one venue that can bring you completely up to date with advances in Biosensors during the past two years. At Biosensors ‘94, nearly 300 carefully selected and original presentations from 32 countries will be made to a capacity audience from around 60 countries.
Mini symposium The congress opens with a mini symposium on Commercial Development and Application of Biosensors. The session is launched appropriately by Dr John Hurrel, the Director of Clinical
X
Chemistry R&D from Boehringer Mannheim, USA. His company will field the largest number of submitted papers accepted by the congress from a single organization and will reveal the breadth of their little-publicised R&D programme on biosensors. The principal competitor for Pharmacia’s surface plasmon resonance-based BIAcore instrument range will be discussed by Dr Denise Pollard-Knight in her description of Fisons’ work on the IASys. Dr Graham Davis (i-Stat) will then present the work behind the launch of their 7-channel clinical chemistry chip incorporating biosensors for glucose and urea. Biosensors for clinical analysis and sports medicine produced by MDC, Berlin will be described by Dr Dorothea Pfeiffer. This first plenary session will be completed by a view from the Environmental Protection Agency of the USA(Dr Kay Rogers) on the future of biosensors for environmental monitoring. This final area is the fastest moving application with the promise of rapid commercial reward. Understanding the intricacies of the demands placed on an analytical device to be used in this arena, however, is essential for success.
0956-5663/94/$7.00
0 1994 Elsevier Science Ltd.
Biosensors & Bioelectronics Vol. 9 No. 2 (1994)
Main symposia The afternoon of the first day sees the launch of the three main symposia, which run in parallel through the congress. The session on Enzyme-based Sensors begins with a series of papers on amperometric biosensors, whereas the Affinity Sensors Symposium starts with an optical bias. The environmental theme is continued by many of the initial papers in the third symposium on Whole Cell-based Sensors. A key feature of the afternoon is the interactive poster session which occupies a central position between the two oral sessions. The themes of this first display are Commercial Development and Application of Biosensors, and Enzyme-based Sensors. Posters are again on view during the sponsored evening reception at which the Biosensors and Bioelectronics Journal Award for outstanding service in the field of Biosensor Technology will be presented.
New Orleans New Orleans is synonymous with one of the most prominent founders of the field, Professor Guilbault, who will present the congress plenary lecture “Biosensors: a New Orleans Perspective”. The theme of amperometric biosensors will then be developed by myself followed by Professor Schmidt from Munich, who has consistently delivered some of the most exacting work in the area. The emotive field of neural networks and electrode arrays will be reviewed by Professor Gross (University of North Texas) and the invited section will be completed by Professor Karube, who will present an inspired view of the future that could only be formed within the context of Japan’s long range strategy in the field. The four symposia themes are picked up again in the afternoon and sandwich the second poster discussion featuring Affinity Sensors, Whole Cell-based Biosensors and General Aspects of Biosensors. A spectacular social event follows in the evening aboard the Creole Queen Paddle Wheeler, during which YSI Inc will
UImffi
PRMEW
present the YSI Biosensor Award for Scientific contribution to the advancement of Biosensor Technology.
Optical theme Friday 3 June, has a particularly strong optical theme flowing through the day although electrochemists can take solace in one of the two parallel enzyme-sensor sessions which focuses on amperometry, or in the Affinity Sensor Symposium. Professor Lundstrom (Linkoping) opens the plenary session with a review of his pioneering work on surface plasmon resonance, which has opened up a second major commercial avenue for biosensors following on from successes with enzyme electrodes. The alternative strategy of using fluorescent labels in combination with waveguides had looked like a more viable commercial strategy, but the launch of viable formats has been delayed. Dr Flanagan (University College London) will examine the options for fluorescence immunosensors. Single-stranded DNA is a powerful recognition element, but harnessing its properties in an affinity sensor format offers particular challenges which will be discussed by Professor Thompson from the University of Toronto. Arguably the newest biological sensing element to be considered for inclusion in biosensors is double-stranded DNA. Russia has led the way in this approach an some recent advances will be described by Professor Yevdokimov (Russian Academy of Sciences, Moscow). The invited sessions will close with a presentation on the enabling subject of surface analysis in biosensor design by Professor Gopel (Tubingen). As biosensor technology matures it becomes increasingly apparent that design considerations must be tackled at a molecular level.
Open interaction In addition to the intense scientific programme, the location of the conference in a single sizable
xi
MEEl’iNQ PREVIEW
venue, the New Orleans Hilton Riverside, will facilitate interactions between key industrialists, opinion leaders, scientists and administrators in the area. As a new addition to the Congress there will be a display of commercial equipment so you can catch up on the latest tools of the trade as well as spotting the newest innovations.
Biosensors & Bioelectronics Vol. 9 No. 2 (1994)
Biosensors ‘94 has something for everybody from those interested in environmental monitoring or clinical chemistry to specialists in food safety or biotechnology. A truly multidisciplinary event, it will bring together optical physicists and biochemists, analytical chemists and engineers to realise the exciting commercial opportunity offered by this fast-moving technology.
Analytical laboratory on an optical chip The world renowned CranfieEd Biotechnology Centre and the “British brecealdhroughin integrated opti&, B&&ham TechnoIw Ltd., have joined iT5~a~cses in a DTVSERC LXNK Molecular Sensors Programme. This collaboration brings together the reqtid expertise to successfully exploit silicon integrated optical chemi-biomsors, namely the experience within integrated optics mauufacturiug and sensor technQlogy. The project is entitled: “Silicon-an-Insulator Integrated Optical Sensors: UItrasensitive C%emi/Biosensiug” and aims to provide a low-cost, multi-analyte auaIytical instrument based on silicon integrated optical evanescent field sensing devices. The duration of the project is 1 year and the final results will be released by the end of 1994. The LINK project will draw on the sub&a&al microengineering resources of Bookham’s rented facilities at the Central Microstructure Facility, Rutherford Appleton Laborato~. This co-operation between Bookham Techuology Ltd. and Craufield Biatechuology Centre is only the start of a &XX?business relationship, The combination of Bookham’s and Cranfield% expertise within integrated optics and sensor teclmology respectively w% ensure further innovative de&u and low-cost manufacture, providing a reaI opporttity for industry. Together they wil1cover alI application area within sensor technology, such as ctiuical diagnostics and euviromeutal monitoring aud detection (e.g. pesticides and herbicides in soil and water, hazardous gases and pullutants, including metals, organics, industrial and agricultural waste), food quality and control and industrial fermentation monitoring. Bookham’s input to the co-operation is the Active Silicon Integrated Optical Circuit manufacturing technology (ASOC) which keeps the cost of fibre and integrated optical devices to a minimum, because it utilizes standard silicon electronic circuit mamfacturiug methods. ASOC was developedwith support from the DTI. The ASCKYmanufacturing technology can not ouIy be applied in developing silica sensors, but also covers such application areas as distance measurermnt and fibre opti telecommunications. En January, a oanaurtium ted by Bookham Technology Ltd. received fl m&m to design optical
telewmmunications components for fibre-to-the-home. Cranfield will add to the collaboration more than twelve years uf experience within development ’ and applicatiun of sensors. CraufieId Biotechnology Centre spe&&ses in fabrication technology for mass production of inexpensive devices and conducts both academic and industrial research. CranGeld has a Iarge team of experts whose work is entirely dedicated to sensors and diagnostics. Together Ganfield BiotechnoIogy an&e and Bookham TahuoIugy Ltd. will work towards more rdiable and bwer cost integrated optical sensors and diagnostics system to service all industries need. Conram D&z ?Q~eil, C~IXK$& Bio~&mology Cent. Teitfkx: [4#] (01234 ?5437(v7505ho?. Mette I%&m~ Book&m TecJmotogy I.&. Tel&m: [44] (0123.5445377Y4468.74.
xii