Blood pressure (BP) early morning rise and left ventricular mass and dimensions

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AJH-APRIL 1996-VOL. 9, NO, 4, PART 2

ASH XI ABSTRACTS

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BLOOD PRESSURE PATTERN IN THE RECOVERY PERIOD AFrER CORONARY ARTERY BYPASS GRAFTING. D Duprez", M De Buyzere, W Fonteyne, G De Backer, G Van Nooten, and DL Clement". University Hospital, Gent, Belgium Arterial hypertension is a major risk for coronary artery disease (CAD), Coronary artery bypass grafting (CABG) improves the prognosis of certain subgroups of severe CAD, but there is no information on 24 h blood pressure (BP) in the recovery period postCABG. Therefore, the aim of the present study was to evaluate the ambulatory BP profile (SpaceLabs) at I and 14 weeks (w) after CABG. Fifteen patients (mean age 64 years) who remained uncomplicated during 14 w follow-up after CABG were studied. Therapy remained unchanged over that period. Data are given as office BP (mm Hg), day time and night time BP, vanabI1ity and heart rate (beats/min). 14 w post CABG Office BP 1 w post CABG Systolic 127±12 13S±16" Diastolic 71±9 76±11 Night time Ambulatory BP Day time Night time Day time Systolic J24±11 1I9±13 134±11"" l29±10 82±1I" 79±IO Diastolic 74±9 69±1O 9.S±3 11.8±3" 13.6±3" Systolic VC IO.0±4 Diastolic VC 8,6±4 7,S±3 9.7±3" 11.2±3" 74±IS 72±12 69±11 Heart rate 78±14 "" p
AFTERNOON BED REST REDUCES BLOOD PRESSURE LIKE AFTERNOON NAP. Waisman G'. Magi M, Galarza C.R", Alfie J, Mayorga LM, CameraM I". HypertensIon Unit Hospital Italiano Buenos Aires. Argentina. Objective: To compare blood pressure level between bed rest and nap in the afternoon. Design and methods: We measured ambulatory blood pressure (mean and total area under the time curve of SSP and DSP) handling s Del Mar IV Fifty-nine mIld hypertensive unmedicated subjects (age 53t14 yr.) were prospectively instructed to sleep In the afternoon (n=22), to rest in bed without sleeping (n=17) or to stay actIve (n=20) ,n the postprandial period. Resulls were tested using repeated measures ANOVA and Bonferroni t-tests Data are reported as meanstSD. Results: There were not differences between groups neither for nocturnal SSP (131t16, 131t25, 127t18 mmHg; p NS) nor for nocturnal DSP (84t7.8, 83t13, 81tl mmHg; p NS) Patients who slept,n the afternoon showed Similar SSP (134t26 vs 138t20 mmHg; p NS) and DSP (80t98 vs 83t9.5 mmHg, p NS) than patients who rested wllhout sleeping, but lower SBP (134t26 vs 149t16 mmHg, p < 0.001) and DBP (80t98 vs 92t8.5; p < 0001) than patients who stayed active Patients who slept in the afternoon showed similar SBP and DSP, and those who rested without sleeping showed significant higher SBP (p
Ambulatory blood pressure monilonng, afternoon rest, afternoon nap

Key Words:

Key Words: ambulatory blood pressure, coronary artery bypass grafting, blood pressure variability

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BLOOD PRESSURE (BP) EARLY MORNING RISE AND LEFT VENTRICULAR MASS AND DIMENSIONS P CodIspoti. M Muscolo, S Bravo. S Angotti. L Federico. V Pecchioh. (O)S DamlaDI. G Germano' * I Climea MedIca & (O)Diomctna. UDlVCfSlt) "La SapIenza", Romc. Italy OBJECTIVE Cross-sectional and longItudinal eVidences suggest that the organ cardiac IDvolvcment of hypertcnslon may depend not only on DP as time span anthmctle mean but also as magnitude of Its changes. Among these, DP early mornmg surge occurs With the longest hnear mterval. The llIm of Jlus study ",as to IDvestlgate wether the RANGE - the mterval dlffercoce between maxunal and mmlmal values - and the "SPEED" - straIght hne slope that represents DP mcrease 10 the umt of tlllle • both smgled out by Fourier analySIS. could mftuence left ventncular morphology determmed byeehocardlography DESIGN AND METHODS 344 patients (aged 47 ± 13yrs) with mild to moderate hypertenSion, never previously treated. underwent a 24-h ambulatory DP momtonng (DAYTIME 7amIlpm. NIGHTTIME llpm-7am. DP nocturnal FALL) and an eehoeardiography study to assess left vcotneular anatomical parameters, categorizing: relative wall thickness (RWT) and mass index (LVMI) WIthin NORMAL limIts. LVMI normal but RWT increased (CONCENTRIC REMODELING). LVMI mereased and RWT normal (ECCENTRIC HYPERTROPHY). LVMI and RWT IDereased (CONCENTRIC HYPERTROPHY). RESULTS

A NEW GRAPHIC APPROACH TO EVAWATION OF AMBULATORY BLOOD PUSSURE (BPI MEASURING DEVICES. Dunuam S, (0) Muscolo M, (0) AngottI S, (0) IJravo S, (") Codlspoll P, (") Fed<.'Ilco I., (0) GermanO GO H".w/no & (oJ I CI",K'tIM«J,ca, U..' .....,1y "IA SapIenza", Rome, IIDly Regardmg 10 Ieslmgs and lINl1yses fOl' the vahdatlon of BP ambulatory momtors It IS useful to have aI one' S dlspooaJ a broad spreclurn of Jll<.'lhodoIPgles Aun of thIS study IS 10 suggest a new grapluc colenon " IS SUItable for companllOll.. between an automau:d deVIce and s mercury column ..,hygmornanorne1er carned out by two obscnen The method " based on thc dIfferences among dcvtces (D) and obscners (A, B) and between obscners (Bhmd cl Altman, lANCET 19l16,1 '07-310) We cvalualod the OSClLLIT (FlGI-ltaly) an mt<:gralod oscIIIODk.'lnc ambulatory BP recorder, WIth oequcnhal, same arm 1llClIlIUI'CIIl1s, m a large, ....1erogencous popuIaltlJll (100 subjects, 52 males, 4g fcmales, mcdJan age and range males 44 5/19-7911 females 54 0/19-74, sphygJl\OlllllllOll readings systohc lrom 90 mmI 'sto 260 mm11g.deR:stuna.... _ 0, A. and B It allows the construchlJll of tables, the calculahon of averages and standard devtatillllS. The grapluc was completed With oonIidence Interval. here not drawed, and also hnuu:d to J()% of expenmental data, for the reduced dunenSlODS. _

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CONCLUSIONS Patients With highest left ventneular pattern values showed no difference on Circadian DP paramcters bUI broader and faster DP nse shape suggestmg that these ulterior measurements of peri.awakenmg DP behaviour Will add mfOrmatlOD on the prediction of target organ damage. Key Words: circadian rhythm, left ventricular hypertrophy.

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Key Words

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BP ambulatory IlIOlUIonn& n1idalJOll.