Body fat distribution, ambulatory blood pressure monitoring (ABPM) and plasma lipid profile in essential hypertension

AJR-APRIL1996-VOL. 9, NO.4, PART 2

POSTERS: Blood Pressure Measurement

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WHICH 24-h ABPM VALUE IS EQUIVALENT TO 140/90 mmHg

BYCASUALMEASUREMENTINTHEELDERLY?~.Arco

C. Blanco F. Saez T. Gabriel R. On behalf the EPICARDIAN Group. There is DOt agreemem about the 24-h ABPM value which corresponds to 140/90 mmHg by casual measurement. It is perfomled a cross-sectional survey of the civilian. noninstitutionalized elderly population (older than 65 years old) (n=3.ooo). including an in-home and an office BP measurement. A 24-h ABPM recording was perfomted in 300 subjects. Awake and sleeping periods were defined. The following variables were evaluated: average of two Systolic and Diastolic home BP readings (SBPH. DBPH). average of two Systolic and Diastolic office BP (SBPO.DBPO). average of 24-h Systolic and Diastolic ABPM (SBP24. DBP24) and average of Systolic and Diastolic BP during the awake period (SBPA.DBPA). A regression lineal was performed between casual and ABPM values. The equivalence to 140/90 mmHg was calculated for ABPM values. X

mmHg SBPH

r

Y mmHg

nunHg

X

r

Y mmHg

.60

SBP24

DBPH

.48

DBP24

.60

SBPA

.47

DBPA

140 SBPH

125

129

140 SBPO

.57

SBPO

SBP24 124.8

140 .58

SBPA

75

90

DBPH

79.5

90

DBPO

.45

DBP24

.48

DBPA

74.3

90

DBPO

78.9 128.7 90 140 The All I'M eqU/valelll va ues to 14U/90 nunHg y ca,ual rea~p are 10 nunHg lower than the casual one if you consider the awake period and IS mmHg lower in the case of 24-h period. for both SBP and DBP. ABPM. elderly. reference-values Key Words:

IIOME BLOOD PRESSURE DURING PREGNANCY ESTABLISHMENT OF STANDARDS OF NORMALCY T DenoHe I, C Calvez2, IN OllavIOli3, V Esnault4. D Herpin5. P Lebon6 I: St Malo, 2: St Bneuc, 3: La Roche SNon,4: Nantes, 5: Poi tiers, 6: Le Mans; France The aim of this study was to establIsh home blood pressure (HBP) standards of normalcy dunng the three different gestational 3 month periods. One nurse in each hospital taught pregnant women HBP and gave them usually on Monday morning a semi-automatic OSCillometric deVice (Hestla Pharma D2 used 10 Hot Study) after calibration agalOst a standard mercury manometer. After IOformed consent, 30 healthy pregnant women Without history of hypertenSion (age. 29 yn;, range 23-36 yrs) underwent BP measurement 3 times bclore breakfast and 3 times after dlOner 10 seated poSition from Monday evenlOg to Saturday evemng. Meaurements taken on Monday evemng were e'(eluded. Only pregnant women With 3 good quality monitorings carned out before 16 weeks of gestation for the first 3-month period (mean: 12), between weeks 17 to 29 for the second 3-month penod (mean: 23) and after 30 wceks for the last 3-month penod (mean: 34) were analysed.

I. Comparison of semi-automatic measurements and manual office BP measurements by the nurse: OffIce BP: 116±1l/ 67±8 mmHg Oscillometnc BP: 112± 13/ 67±8 mmHg 2. HBP 10 healthy pregnant women: First tnmester: 103± 8/ flJ±7 mmHg Second tnmester: 103±7/ flJ±9 mmHg Third Inmesler. 107±7/63±8 mmHg (p 119/74. 117/78. 121/79 mmHg respectively dunng the 3 gestational 3-month penods have probable hyperlenslOn. HB P after 30 weeks of gestation was slgmflcantly hlghcr than dunng the 2 others gestational penods. These HBP resllll~ .Irc compamble 10 published ambulatory BP normal values. Key words: Home blood pressure measurement; Pregnancy; normal values

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E55 BODY FAT DISTRIBUTION, AMBULATORY BLOOD PRESSURE MONITORING (ABPM) AND PLASMA LIPID PROFILE IN ESSENTIAL HYPERTENSION. CA Feldstein·, M Akopian. AO Olivieri. H Chavin, S Cauterucci. R Paladino, F Passarini, E SalvatierrL Hypertension Proeram. University of Buenos Aires and Health Sciences Institute. Buenos Aires. Areentina. The aim of the study was to evaluate the association of anthropometric measurements and serum lipids with casual BP and ABPM in men with untreated essential hypertension. There were ell8mined 89 men. aged 18· 84 yrs. Blood pressures were measured in triplicate with a mercury sphy&momanometer. ABMP were obtained on a workday with a TM 2421 (AND CAl taken readines at IS-min intervals during the day and at 30-min intervals during the hours of sleep. Averaees were then be calculated for three intervals: 7AM-IPM; 7AM-11 PM. and 11 PM-7AM. Total cholesterol. HOL-cholesterol. and triglycerides were measured usine established euidelines. Height was significantly correlated with DBP 7AM-llPM (r=O.223, p
Key Words Body fat. ABPM, serum lipids

BLOOD PRESSURE MONITORING IN ESSENTIAL HYPERTENSIVES TREATED WITH QUINAPRIL AND HYDROCHLOROTHYAZIDE M.Biagini, G. Busi. G. Roscio, F. Pasquazzi Infermeria Presidiaria A.M. 2° R.A. ROMA We enrolled 50 patients.42 men (mean age 49T 5 ys) and 8 women ( mean age 45: 4 ys) with systolic blood pressure ( SBP) between 160 and 200 mm Hg and diastolic blood pressure (DBP) between 90 and 105 rom Hg. After 2 weeks of pharmacological wash-out,we recorded an E.C.G. and an echocardiographic exam in all patients;besides the circadian behaviour of blood pressure values was studied in all patients by non-invasive. automatlc,lntermlttent monitoring. All patients were treated with a combination of Quinapril 20 mg + Hydrochlorothyazide 12.5 mg for a period of 12 weeks,starting with 1/2 pill and dOUbling the dose in non-responding patients after 2 weeks. The monitoring of blood pressure,performed at the end of treatment,showed a significant reduction both of SBP , (-12.4 % ) and of DBP (- 11.2 %}.Moreover a significant diminution of the hypertensive peaks was noticed during daytime recordings. Heart rate showed no significant change at the end of treatment. Key Words: Blood pressure moni toring. Quinapril. Hydrochlorothyazide

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