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BRONCHIAL ASTHMA. MECHANISMS AND THERAPEUTICS
BRONCHIAL ASTHMA. MECHANISMS AND THERAPEUTICS. Edited by EARLE B. WEISS, MAURICE S. SECAL, and MYRON STEIN. Boston: Little Brown and Co, 1985,982 pp. $95.00
This comprehensive text Bourishes in its second edition, boasting 126 contributing authors. It is clearly laid out in three sections: mechanisms, clinical considentions and therapeutics, and therapy and patient management. Each chapter is written by a leader in the &eld and is invariably wellreferenced, with as many as 511references per chapter. The editors succeed in integrating and organizing individual contributions into a balanced state of the art review ofasthma. Themajority ofcontributing authors have changed since the 8m edition of 1976. Kenneth M. Moser, Homer A. Boushey, Margaret 1brner-Warwick, Ann Woolcock, James C. Hog and Carol A. Hirshman, to mention just a few, have added new and interesting information. With the change in authors, there have been changes in emphasis, especially in the mechanisms section. For example, chapters by Lynne M. Reid and Adam Wanner introduce the relevance of mucus and mucocl1iary function, respectively. The chapter on clinical considerations and therapeutics updates the reader on the changes of approach and usage of medication that has occured mer the past decade, dropping the chapter on ·Marihuana and Respiratory FUnction" and inserting ·Sex and Asthma"-a sign of the times? In summary, the second edition adds new uoormation on pathophysiology and updates clinical management, and I would agree with the editors that thisbook ofters "a comprehensive review of physiology and therapy." I can therefOre strongly recommend this reference text as an invaluable addition to the bookshelves of a1lergists and pulmonologists and those with a particular interest in asthma. Moira Aitken, M.D.
Seattle
THE CORONARY SINUS: PROCEEDINGS OF THE 1ST INTERNATIONAL SYMPOSIUM ON MYOCARDIAL PROTECI10N VIA THE CORONARY SINUS. Edited by W. MORL, E. WOLNER, and D. GLOCAR. New York: Springer-Verlag, 1984, 556 pp. $63.00
It bas been mer 80 years since the coronary sinus was 6rst suggested as an alternate pathway b myocardial nourishment during acute cardiac ischemia, and more than 30 years since Beck developed and applied coronary sinus arterialization in sewral hundred patients suffering from coronary artery disease. Despite early promising results, the Beck procedure was abandoned because of high surgical mortality and the introduction of coronary artery bypass graft surgery. Nevertheless, interest in the coronary sinus for myOC8J'o dial protection has persisted and, recently, several groups of investigators have reported encouraging results employing the coronary venous system fOr cardioplegia administration, myocardial salvage during acute myocardial ischem~ and regional myocardial revascularization. In February, 1984, many of these investigators assembled in Vienna, Austria fOr the lst International Symposium on Myocardial Protection via the Coronary Sinus. The symposium proceedings are published in this book. The test is divided into two parts: Part A-FUndamentals, which reviews the coronary venous anatomy and coronary arterial and venous physiology and pathophysiology; and Part B-Myocardial Protection, dealing with applications of coronary sinus interventions tOr cardioplegia delivery, selective venous arterialization, SYnchronized diastolic reboperfusion and intermittent coronary sinus occlusion. Many of the papers report results of original research but stdFer from lack of peer revie'\Y. Nevertheless, this text is the most comprehensive collection of articles available dealing with the use of the coronary veins tOr acute and chronic cardiac therapy. The symposium proceedings should be of interest to the increasing number of cardiologists and cardiac surgeons who are rediscovering this novel and potentially important alternate therapeutic approach.
J. Kevin D",'lI, M.D.
Lo,Angelu
CEREBROVASCULAR DISEASES, 14th Research Princeton-Williamsburg Conference. Edited by FRED PLUM and WILLIAM A. PULSINELU. New York: Raven Press, 1985, 259 pp, $69.00 As the major source of chronic, humiliating disability, the ravages of vascular disease on mans supreme organ continues to warrant our attention. This interdisciplinary book clari6es what we only Partially know and identi&es
where some important, unanswered problems lie. A major revision in thinking has occurred regarding the importance of neurogenic control of the cerebral circulation. The &rst chapter establishes that there may well be systems in the brain that have a widespread influence on cerebral blood 80w (CBF) and metabolism. This line of inquiry promises rich nmmcations tOr future discoYery. Next, under unsolved clinical problems, the conservative view against strokeprevention by carotid endarterectomy is presented. This section fails to mention the important recent prospective, noninvasive evidence suggesting that when an asymptomatic carotid stenosis exceed 80 percent, carotid endarterectomy is probably indicated. (Roederer GO, et ale Natural history of carotid arterial diseasesin asymptomatic patients with cervical bruits. Stroke, 1984; 15:6CWS-13) Furthermore, although shotgun, staccato-like vollies ofTIAs are rightly interpreted as caused by low 8ow, the obvious therapeutic conclusion, emergency carotid endarterectomy, is not mentioned.
[aJ
AMERICANOF COLLEGE CHEST PHYSICIANS
Postgraduate Course
UPDATE IN CARDIOPULMONARY MEDICINE Course Co-diredors: Merle R. Bolton, M.D., FCCP Marvin I. Dunn, M.D., FCCP Susan K. Pingleton, M.D., FCCP Dates: February 13-15, 1986 Location: Annenberg Center for Health Sciences of Eisenhower Medical Center, Rancho Mirage, California Course Description: • Recent advances in diagnostic techniques and practical aspects of therapeutics • New approaches to clinical management of cardiopulmonary problems • Advances in pulmonary diagnostic imaging • Current and future surgical approaches to cardiopulmonary problems Co-sponsors: American College of Chest Physicians Annenberg Center for Health Sciences For further information contact:
Division of Education, ACCP 911 Busse Highway Park Ridge, IL 60068-2375 (312) 698-2200 .
Continued on page 22
21
This comprehensive text Bourishes in its second edition, boasting 126 contributing authors. It is clearly laid out in three sections: mechanisms, clinical considentions and therapeutics, and therapy and patient management. Each chapter is written by a leader in the &eld and is invariably wellreferenced, with as many as 511references per chapter. The editors succeed in integrating and organizing individual contributions into a balanced state of the art review ofasthma. Themajority ofcontributing authors have changed since the 8m edition of 1976. Kenneth M. Moser, Homer A. Boushey, Margaret 1brner-Warwick, Ann Woolcock, James C. Hog and Carol A. Hirshman, to mention just a few, have added new and interesting information. With the change in authors, there have been changes in emphasis, especially in the mechanisms section. For example, chapters by Lynne M. Reid and Adam Wanner introduce the relevance of mucus and mucocl1iary function, respectively. The chapter on clinical considerations and therapeutics updates the reader on the changes of approach and usage of medication that has occured mer the past decade, dropping the chapter on ·Marihuana and Respiratory FUnction" and inserting ·Sex and Asthma"-a sign of the times? In summary, the second edition adds new uoormation on pathophysiology and updates clinical management, and I would agree with the editors that thisbook ofters "a comprehensive review of physiology and therapy." I can therefOre strongly recommend this reference text as an invaluable addition to the bookshelves of a1lergists and pulmonologists and those with a particular interest in asthma. Moira Aitken, M.D.
Seattle
THE CORONARY SINUS: PROCEEDINGS OF THE 1ST INTERNATIONAL SYMPOSIUM ON MYOCARDIAL PROTECI10N VIA THE CORONARY SINUS. Edited by W. MORL, E. WOLNER, and D. GLOCAR. New York: Springer-Verlag, 1984, 556 pp. $63.00
It bas been mer 80 years since the coronary sinus was 6rst suggested as an alternate pathway b myocardial nourishment during acute cardiac ischemia, and more than 30 years since Beck developed and applied coronary sinus arterialization in sewral hundred patients suffering from coronary artery disease. Despite early promising results, the Beck procedure was abandoned because of high surgical mortality and the introduction of coronary artery bypass graft surgery. Nevertheless, interest in the coronary sinus for myOC8J'o dial protection has persisted and, recently, several groups of investigators have reported encouraging results employing the coronary venous system fOr cardioplegia administration, myocardial salvage during acute myocardial ischem~ and regional myocardial revascularization. In February, 1984, many of these investigators assembled in Vienna, Austria fOr the lst International Symposium on Myocardial Protection via the Coronary Sinus. The symposium proceedings are published in this book. The test is divided into two parts: Part A-FUndamentals, which reviews the coronary venous anatomy and coronary arterial and venous physiology and pathophysiology; and Part B-Myocardial Protection, dealing with applications of coronary sinus interventions tOr cardioplegia delivery, selective venous arterialization, SYnchronized diastolic reboperfusion and intermittent coronary sinus occlusion. Many of the papers report results of original research but stdFer from lack of peer revie'\Y. Nevertheless, this text is the most comprehensive collection of articles available dealing with the use of the coronary veins tOr acute and chronic cardiac therapy. The symposium proceedings should be of interest to the increasing number of cardiologists and cardiac surgeons who are rediscovering this novel and potentially important alternate therapeutic approach.
J. Kevin D",'lI, M.D.
Lo,Angelu
CEREBROVASCULAR DISEASES, 14th Research Princeton-Williamsburg Conference. Edited by FRED PLUM and WILLIAM A. PULSINELU. New York: Raven Press, 1985, 259 pp, $69.00 As the major source of chronic, humiliating disability, the ravages of vascular disease on mans supreme organ continues to warrant our attention. This interdisciplinary book clari6es what we only Partially know and identi&es
where some important, unanswered problems lie. A major revision in thinking has occurred regarding the importance of neurogenic control of the cerebral circulation. The &rst chapter establishes that there may well be systems in the brain that have a widespread influence on cerebral blood 80w (CBF) and metabolism. This line of inquiry promises rich nmmcations tOr future discoYery. Next, under unsolved clinical problems, the conservative view against strokeprevention by carotid endarterectomy is presented. This section fails to mention the important recent prospective, noninvasive evidence suggesting that when an asymptomatic carotid stenosis exceed 80 percent, carotid endarterectomy is probably indicated. (Roederer GO, et ale Natural history of carotid arterial diseasesin asymptomatic patients with cervical bruits. Stroke, 1984; 15:6CWS-13) Furthermore, although shotgun, staccato-like vollies ofTIAs are rightly interpreted as caused by low 8ow, the obvious therapeutic conclusion, emergency carotid endarterectomy, is not mentioned.
[aJ
AMERICANOF COLLEGE CHEST PHYSICIANS
Postgraduate Course
UPDATE IN CARDIOPULMONARY MEDICINE Course Co-diredors: Merle R. Bolton, M.D., FCCP Marvin I. Dunn, M.D., FCCP Susan K. Pingleton, M.D., FCCP Dates: February 13-15, 1986 Location: Annenberg Center for Health Sciences of Eisenhower Medical Center, Rancho Mirage, California Course Description: • Recent advances in diagnostic techniques and practical aspects of therapeutics • New approaches to clinical management of cardiopulmonary problems • Advances in pulmonary diagnostic imaging • Current and future surgical approaches to cardiopulmonary problems Co-sponsors: American College of Chest Physicians Annenberg Center for Health Sciences For further information contact:
Division of Education, ACCP 911 Busse Highway Park Ridge, IL 60068-2375 (312) 698-2200 .
Continued on page 22
21