S62
Courses
-
Cutaneous
malignant melanoma will donate every 6-10 years. The detection of precancerans skin eruption can be of great value in the prevention for skin cancer. Actinic keratosis (AK) is very common among people above the age of 60. Up to now most dermatologist will treat AK with 5fluorouracil and/or liquid nitrogen. As more and more people are seen with severe actinic alterations of the skin a more complete work up is necessary. (1) Teaching people to be careful in the sun, and use sunscreens with a high protection for UVA and B. (2) Chemical peeling: initially a Jessner-TCA-peeling is very helpful. We can discuss about a long term treatment with glycolic acid on a home base. (3) Skin resurfacing: C02-resurfacing and also the ErbuimYag laser offers a good tool in a total face treatment. (4) Photodynamic therapy: although extensive experience is lacking, this seems to be a good treatment possibility for the near future. ElCO15 Epidemiology of squamous cell carcinoma C. GuillCn, R. Botella, A. Escudero, 0. Sanmartin. Setvicio Dermtologia, Spain
Institute
Valenciano
de Oncologia,
Valencia,
Squamous cell carcinoma accounts for one-fifth of the nonmelanoma skin cancers. Whereas the risk of metastasis from basal cell carcinoma is extremely low, squamous cell carcinoma (SCC) has an stimated metastatic risk of l-2%. The development OS SCC in an individual is related to two factors: constitutional predisposition determined by the skin color and environmental factor, mainly sunlight. As SCC is most often sun induced, fair-skinned people with excessive sun exposure are at highest risk. Arsenic ingestion, immunosuppression and PLJVA treatment for psoriasis are other factors implicated in the development of SCC. Programs promoting a reduction of sunexposure and regular use OS sunscreens have demonstrated useful in the prevention of skin cancer.
CO16 What is new: Diagnosis and treatment of cutaneous malignancy P.J.A. Holt. University
Hospital
of Wales,
Card@
UK
The prevalence of non-melanoma skin cancer (NMSC) continues to rise in white populations. Ageing and sun exposure are important, but immunosuppression is a further aggravating factor. NMSC occurs more frequently in renal transplant recipients than the general population - and the risk of NMSC has increased since the introduction of cyclosporin. In-situ or early invasive tumours may be treated with photodynamic therapy (PDT) using topical 5aminolaevulinic acid. PDT has been shown to be as effective as cryotherapy in treatment of Bowen’s disease The role of chemoprevention with retinoids needs to be reassessed in populations at risk. Recurrences of basal cell carcinoma after incomplete first excision is common. These tumours should be re-excised with an appropriate margin, using margin control if possible. Outcomes following surgery should measure aesthetic appearance and function, and should always include assessment of tumour clearance.
Radiotherapy
CO17 El
Education in skin cancer
Perry Robins. USA The goal of the physician and public education is to inform both patients and physicians. The physician conveys his messages by means of brochures, posters, books, newsletters, public service announcements, and audiovisual materials. These are distributed to the general public, the media, physicians’ offices, screening clinics, health fairs, corporate and community wellness programs, and schools. The physician is able to gain national and international recognition as a major resource for the print and broadcast media. Timely information is provided regularly, and a national media conference highlights medical advances. The purpose of this talk is to inform as to the methods and availability of information on skin cancer.
Cutaneous Radiotherapy
ICO18
Radiotherapy of benign and premalignant skin diseases
Renato G. Panizzon. CHUV-Lamanne,
Switzerland
In the first part the good results of radiotherapy, especially with Grenz rays in chronic eczemas, and psoriasis of the scalp and nails are shown. Excellent results are also achieved in keloids if radiotherapy starts immediately after surgery. In the second part the results in premalignant skin lesions, such as disseminated actinic keratoses, Bowen’s disease (97% cure rate) or lentigo maligna (99% cure rate) are shown.
CO19 El
Electron therapy for skin tumours
Margaret F. Spittle. England Multidisciplinary clinics ensure that all forms of treatment are considered for oncology patients. Radiotherapy for skin tumours is an important alternative to other forms of more invasive therapy such as surgery. Radiotherapy is particularly useful for the elderly and those with large or multiple lesions. Basal cell and squamous cell carcinomas involving the ear, nose and the area around the eye are particular indications for radiotherapy, especially where surgery is complicated and less cosmetically acceptable. Treatment is non-invasive and does not involve either local or general anaesthetic. Electron beam therapy is important when treating areas overlying cartilage where the vascularity can be compromised by orthovoltage irradiation. Cutaneous lymphomas are acutely radiosensitive and any individual lesion can be completely resolved by a few fractions of orthovoltage irradiation. However when the lesion is part of a systemic disease, such as in aggressive B cell lymphoma, this treatment is then complementary to systemic chemotherapy. Radiotherapy is an important adjunct to PUVA therapy in T cell lymphoma. With widespread tumour stage disease electron beam therapy of the whole skin exploits the depth dose characteristics of the electron beam, treating the skin to a maximum dose while sparing the deeper tissues.