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Can men with spinal cord injury have children?
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SCI fertility / Annals of Physical and Rehabilitation Medicine 59S (2016) e107–e108
Keywords Lumbosacral spinal cord injury; Ejaculation rate; Premature ejaculation; Dribbling ejaculation Disclosure of interest The authors declare that they have no competing interest.
Disclosure of interest peting interest.
The authors declare that they have no com-
http://dx.doi.org/10.1016/j.rehab.2016.07.239
http://dx.doi.org/10.1016/j.rehab.2016.07.238 CO070
CO071
Outcomes of cryopreserved sperm in case of spinal cord injury in Lyon, France
Can men with spinal cord injury have children?
Perrine Séguin 1,2,∗ , Kathleen Charvier 2,5 , Frédérique Courtois 2,4 , Corinne Del Aguila 2,5 , Bruno Fernandez 1,2 , Gilles Rode 2,3 , Jacqueline Lornage 2,6 , Alain Ruffion 2,7 , Sandrine Giscard d’Estaing 2,6 1 CHU de Saint-Étienne, MPR, Saint-Étienne, France 2 Université-Jean Monnet, Saint-Étienne, France 3 Hospices civils de lyon, rééducation neuropérinéale et sexologique, Lyon, France 4 Université du Québec, sexologie, Quebec, Canada 5 Hôpital Henry-Gabrielle, médecine physique et réadaptation, Saint-Genis-Laval, France 6 Hôpital Femme–Mère-Enfant, hospices civils de Lyon, médecine de la reproduction, Bron, France 7 Centre hospitalier Lyon Sud, hospices civils de Lyon, urologie, Pierre-Bénite, France ∗ Corresponding author. E-mail address: [email protected] (P. Séguin) Objective Sperm cryopreservation can be offered to men with spinal cord injury, as only 10% of spinal cord injured men (SCI) can have a child without assistive reproductive technologies (ART). Very few studies are dedicated to the outcomes of these cryopreservations. Our study aims to analyze the outcomes of these cryopreservation, namely their use or not for an ART, and to evaluate the success rate in case of ART. Material/patients and methods In May 2015, we retrospectively identified all people with stable spinal cord injury sent to the CECOS (Centre d’études de la conservation des œufs et du sperme: Egg, Sperm Embryo banking) by the department of neuroperineology based in the hospital Henry Gabrielle, for the first time between 1st January 2009 and 31st December 2013, to undergo a sperm cryopreservation of spermatozoa. Results In June 2015, among the 65 men surveyed, 22 had a medical consultation as a couple for an AMP. Among these 22 couples, 11 have engaged in a program of medically assisted procreation. Thirty-two trials of medically assisted procreation were realized: 5 intrauterine inseminations (IUI), 16 in vitro fecondation (IVF) with intracytoplasmic sperm injection (ICSI) and 11 frozen embryo transfers (FET). Eleven clinical pregnancies were obtained. Six pregnancies were completed and7 children were born healthy. Six of 11 couples had at least one child. We also analyse the spermatic parameters of the cohort of 65 men with spinal cord injury, which are similar to those usually seen in the literature (numeration conserved, but decreased spermatic volume, altered morphologies and mobilities of sperm). Discussion–conclusion Our study helps to assess the results of this very specific and multidisciplinary ART care, which remains largely uninvestigated, in order to optimize its effectiveness. Keywords Assisted reproductive technology; Cryopreservation; Fertility; Pregnancy outcomes; Spinal cord injury
Caroline Voiry 1,∗ , Kathleen Charvier 2 , Frédérique Courtois 3 , Pascal Giraux 1 , Corinne Berthelot-Del Aguila 2 , Gille Rode 2 1 Bellevue, MPR, Saint-Étienne, France 2 Henry-Gabrielle, MPR, Saint-Genis-Laval, France 3 Institut de réadaptation Gingras-Lindsay, Montréal, Canada ∗ Corresponding author. E-mail address: [email protected] (C. Voiry) Objective Most French people think that disabled people do not have any sexual life in terms of pleasure and reproduction. Or sex contributes to a great part of each individual’s well-being and health. In our study, we determined the reproductive sexuality of men with an exclusively traumatic spinal cord injury (SCI) treated at the Henry-Gabrielle Hospital in Saint-Genis-Laval from January 2000 to December 2010, who benefited, or not, from a sexological assessment. Material/patients and methods This is an observational and retrospective study on the number of births in a cohort of 320 men with SCI, aged from 18 to 45 years at the time of their accident and who have an exclusively traumatic SCI without any evolution. The database has been fulfilled by an analysis of their medical records and a self-administered questionnaire. Results In total, 129 men out of the 320 participants who have SCI completed the survey. Forty-eight men out of those 129 became fathers. For those who have an entire SCI, the percent of success to have a child after the accident is 30.8% versus 41,2% for those who have lesions incomplete (P > 0.05). The average delay between the date of accident and the age of becoming father is 8.6 years. On one hand, men are around 24.3 when their get injured. On the other hand, the middle age to become father for the first time is 34 years old. Among those 48 new fathers, 29% conceived their child without assistance, 69% with medical assisted procreation and the left 2% had to adopt. The total number of birth stands at 77 living babies. Moreover, men who benefited from a sexological assessment have more chance to procreate without medical assistance than men who do not (respectively 12.6% versus 4.4%) (P < 0.05). Discussion–conclusion Men with spinal cord injury with different lesion and completeness are able to conceive children with or without medical assisted procreation. Our study shows that both a sexological assessment and the sperm conservation in a freezer increase the chance of becoming a father for men who have a traumatic spinal cord injury. Keywords Traumatic spinal cord injury; Men; Reproduction; Paternity; Procreation; Medical assisted procreation Disclosure of interest The authors have not supplied their declaration of competing interest. http://dx.doi.org/10.1016/j.rehab.2016.07.240
SCI fertility / Annals of Physical and Rehabilitation Medicine 59S (2016) e107–e108
Keywords Lumbosacral spinal cord injury; Ejaculation rate; Premature ejaculation; Dribbling ejaculation Disclosure of interest The authors declare that they have no competing interest.
Disclosure of interest peting interest.
The authors declare that they have no com-
http://dx.doi.org/10.1016/j.rehab.2016.07.239
http://dx.doi.org/10.1016/j.rehab.2016.07.238 CO070
CO071
Outcomes of cryopreserved sperm in case of spinal cord injury in Lyon, France
Can men with spinal cord injury have children?
Perrine Séguin 1,2,∗ , Kathleen Charvier 2,5 , Frédérique Courtois 2,4 , Corinne Del Aguila 2,5 , Bruno Fernandez 1,2 , Gilles Rode 2,3 , Jacqueline Lornage 2,6 , Alain Ruffion 2,7 , Sandrine Giscard d’Estaing 2,6 1 CHU de Saint-Étienne, MPR, Saint-Étienne, France 2 Université-Jean Monnet, Saint-Étienne, France 3 Hospices civils de lyon, rééducation neuropérinéale et sexologique, Lyon, France 4 Université du Québec, sexologie, Quebec, Canada 5 Hôpital Henry-Gabrielle, médecine physique et réadaptation, Saint-Genis-Laval, France 6 Hôpital Femme–Mère-Enfant, hospices civils de Lyon, médecine de la reproduction, Bron, France 7 Centre hospitalier Lyon Sud, hospices civils de Lyon, urologie, Pierre-Bénite, France ∗ Corresponding author. E-mail address: [email protected] (P. Séguin) Objective Sperm cryopreservation can be offered to men with spinal cord injury, as only 10% of spinal cord injured men (SCI) can have a child without assistive reproductive technologies (ART). Very few studies are dedicated to the outcomes of these cryopreservations. Our study aims to analyze the outcomes of these cryopreservation, namely their use or not for an ART, and to evaluate the success rate in case of ART. Material/patients and methods In May 2015, we retrospectively identified all people with stable spinal cord injury sent to the CECOS (Centre d’études de la conservation des œufs et du sperme: Egg, Sperm Embryo banking) by the department of neuroperineology based in the hospital Henry Gabrielle, for the first time between 1st January 2009 and 31st December 2013, to undergo a sperm cryopreservation of spermatozoa. Results In June 2015, among the 65 men surveyed, 22 had a medical consultation as a couple for an AMP. Among these 22 couples, 11 have engaged in a program of medically assisted procreation. Thirty-two trials of medically assisted procreation were realized: 5 intrauterine inseminations (IUI), 16 in vitro fecondation (IVF) with intracytoplasmic sperm injection (ICSI) and 11 frozen embryo transfers (FET). Eleven clinical pregnancies were obtained. Six pregnancies were completed and7 children were born healthy. Six of 11 couples had at least one child. We also analyse the spermatic parameters of the cohort of 65 men with spinal cord injury, which are similar to those usually seen in the literature (numeration conserved, but decreased spermatic volume, altered morphologies and mobilities of sperm). Discussion–conclusion Our study helps to assess the results of this very specific and multidisciplinary ART care, which remains largely uninvestigated, in order to optimize its effectiveness. Keywords Assisted reproductive technology; Cryopreservation; Fertility; Pregnancy outcomes; Spinal cord injury
Caroline Voiry 1,∗ , Kathleen Charvier 2 , Frédérique Courtois 3 , Pascal Giraux 1 , Corinne Berthelot-Del Aguila 2 , Gille Rode 2 1 Bellevue, MPR, Saint-Étienne, France 2 Henry-Gabrielle, MPR, Saint-Genis-Laval, France 3 Institut de réadaptation Gingras-Lindsay, Montréal, Canada ∗ Corresponding author. E-mail address: [email protected] (C. Voiry) Objective Most French people think that disabled people do not have any sexual life in terms of pleasure and reproduction. Or sex contributes to a great part of each individual’s well-being and health. In our study, we determined the reproductive sexuality of men with an exclusively traumatic spinal cord injury (SCI) treated at the Henry-Gabrielle Hospital in Saint-Genis-Laval from January 2000 to December 2010, who benefited, or not, from a sexological assessment. Material/patients and methods This is an observational and retrospective study on the number of births in a cohort of 320 men with SCI, aged from 18 to 45 years at the time of their accident and who have an exclusively traumatic SCI without any evolution. The database has been fulfilled by an analysis of their medical records and a self-administered questionnaire. Results In total, 129 men out of the 320 participants who have SCI completed the survey. Forty-eight men out of those 129 became fathers. For those who have an entire SCI, the percent of success to have a child after the accident is 30.8% versus 41,2% for those who have lesions incomplete (P > 0.05). The average delay between the date of accident and the age of becoming father is 8.6 years. On one hand, men are around 24.3 when their get injured. On the other hand, the middle age to become father for the first time is 34 years old. Among those 48 new fathers, 29% conceived their child without assistance, 69% with medical assisted procreation and the left 2% had to adopt. The total number of birth stands at 77 living babies. Moreover, men who benefited from a sexological assessment have more chance to procreate without medical assistance than men who do not (respectively 12.6% versus 4.4%) (P < 0.05). Discussion–conclusion Men with spinal cord injury with different lesion and completeness are able to conceive children with or without medical assisted procreation. Our study shows that both a sexological assessment and the sperm conservation in a freezer increase the chance of becoming a father for men who have a traumatic spinal cord injury. Keywords Traumatic spinal cord injury; Men; Reproduction; Paternity; Procreation; Medical assisted procreation Disclosure of interest The authors have not supplied their declaration of competing interest. http://dx.doi.org/10.1016/j.rehab.2016.07.240