CANCER RESEARCH AT MANCHESTER.

CANCER RESEARCH AT MANCHESTER.

CANCER RESEARCH AT MANCHESTER- 1421 absolutely negative results. These are the essential parts of the sanitary authority may cause the position of t...

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CANCER RESEARCH AT MANCHESTER-

1421

absolutely negative results. These are the essential parts of the sanitary authority may cause the position of the medical, the process. Hydrolysis with hydrochloric acid appears to officer of health, if he is also in general practice, to be misbe necessary to decompose a sulphonated morphine derivative interpreted. We think that this notice should be withdrawn which is elaborated in the system. The choice of amylic and redrafted. alcohol as a solvent for morphine is in accord with the best POST-GRADUATE STUDY IN LONDON. Details are results of experienced English toxicologists. IN spite of the excellent work which is being done by the given of four experiments with rabbits. An interesting portion of the research deals with the resistance of morphine London Post-Graduate Association, the Medical Graduate to decomposition in cases of putrefaction of a body. A dog College and Polyclinic, the West London Post-Graduate was dosed hypodermically with 0’9 gramme of morphine College, and the North-East London Post-Graduate College, hydrochloride in two days. The body was allowed to it must be confessed that the facilities for post-graduate study decompose during two months, after which the employment offered by London are far short of the requirements and that of the above process revealed the presence of morphine and London with its unique field for clinical work is in this a little oxymorphine in the liver and kidneys, and of oxyrespect distinctly behind Vienna, New York, and Philamorphine and a little morphine in the urine found in the delphia, not to name other cities. We are therefore glad to bladder at the necropsy. learn that an important addition to the list of post-graduate nstitutions will shortly be made. In 1889 the Seamen’s CANCER RESEARCH AT MANCHESTER. Hospital Society successfully instituted in connexion with its branch hospital at the Royal Albert Dock the London THE trustees of the Pilkington Cancer Research Fund School of Tropical Medicine for the training of students are about to appoint a graduate in medicine or other qualified person to carry out a research in this subject for work in the tropics. The society now proposes to utilise and invite applications for the post. The appoint- its Dreadnought Hospital at Greenwich for the purposes of ment will be for one year but may be renewed for a London School of Clinical Medicine (as it is proposed to This hospital, term it) for ordinary post-graduate study. a further period of one or two years and the holder of the post will receive an income of £300 per containing as it does 250 beds and fed by a large dispensary annum with a grant for laboratory expenses. Applications, in the East India Dock-road, offers good opportunities for stating experience of research in biology and medicine, and clinical work, particularly as it possesses special wards giving the name of the professor or head of a laboratory to for venereal diseases and for tuberculosis and has facilities whom reference may be made, should be forwarded to Pro- for teaching operative surgery not elsewhere obtainable, which fessor G. A. Wright at the Victoria University of Manchester, have long been known and recognised. Moreover, the recent, from whom further information as to the conditions of the resignation of the principal medical officer, Mr. W. Johnson appointment may be obtained. It may be explained, how- Smith, has rendered a suite of rooms available for conversion. ever, that candidates must be prepared to give their whole into laboratories, museum, library, lecture rooms, and so on. time to research into the cause, prevention, and cure of By the development of its out-patient and special departments, by the addition to the present staff of teachers of cancer. recognised standing and ability, and possibly by an affiliation for teaching purposes with other special hospitals south NOTIFICATION OF INFECTIOUS DISEASES BY of the Thames, the school will be able to provide exceptional HOUSEHOLDERS. for study in all branches of medical science and; MISUNDERSTANDINGS and difficulties with regard to noti- opportunities The sister institutions at the Albert Dock and at. art. fication of infectious disease are happily now less frequent Greenwich will be complemental and it cannot be doubted than in the years which followed the passing of the first will be mutually helpful one to the other. The Seamen’s. Act on the subject. For ordinary purposes the respective Hospital Society, in thus founding educational institutions, positions of local sanitary authorities, medical officers of has avoided the possibility of its schools becoming a burden health, medical practitioners, and householders in regard to on the charity by exacting guarantees that these shall not. notification have become settled on well-recognised lines. be self-supporting but that a proportion of any profit-, only This is the case, for example, regarding the dual system be allocated to the charity. The universal of notification prescribed by the Act. practice is for the sanitary authority to recognise that THE PHARMACOLOGICAL ACTION OF BENZENE notification by the medical practitioner absolves the houseAND ITS DERIVATIVES. holder from himself notifying the existence of infectious Chassevant and M. Garnier have made in the Journal M. disease in his house. In case of neglect to notify the sanide Pharmacie et de Chemie of July 16th an important, tary authority takes action against the householder only when no medical advice has been obtained. We do not think that contribution to our knowledge of the pharmacological action of members of the benzene series. The physiological a local authority should depart from this custom without some very special reason. A handbill which has lately been action of benzene is exerted chiefly on the nervous system distributed from house to house in the Caistor rural district and causes convulsions, loss of muscular power (hpvotonie), in consequence of the prevalence of scarlet fever, calls upon and above all a lowering of temperature (hypothermie). the householder immediately to give notice to the medical These effects are increaed by the substitution of one or twoofficer of health of the district of any case of infectious hydroxyl radicles (a fact which has been observed by previous disease "whether he employs his private medical man or workers) or by the simultaneous substitution in the same not," and the notice goes on to state the fine which molecule of a hydroxyl radicle and a hydrocarbon radicle. may be imposed for non-compliance with this demand. On the other hand, these undesirable effects are suppressed Now if the reason for this handbill is that some by the substitution of hydrocarbon radicles, or of a medical men in the district are believed to be dilatory carboxyl radicle, or by the simultaneous substitution of in notifying, the sanitary authority has its remedy against a hydroxyl and a carboxyl radicle. The toxicity of them. But if this be the reason there seems no advantage benzene undergoes, by the substitution of one or more in giving quite unnecessary trouble to every householder who of the radicles studied, changes which depend on the has a case of infectious disease in his house and obtains nature of the substituted radicle, and vary with its medical advice in the ordinary way. As a practical matter the molecular weight and with the number and position of thesedemand is sure to be disregarded. Moreover, the notice of substitutes. From a therapeutic point of view preference ____

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