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Cancer, Vol. 60, No. 3, August 1, 1987
Medical Dosime/r~, Vol. 13. pp. 37-44 Printed I” the U.S.A. All rights reserved.
0739-021 l/88 $3.00 + .OO Copyright 0 1988 American Association of Medical Dosimetrists
?? Literature Reviews BETH YANKE
A study of 35 patients with 67 measurable cutaneous or lymph node metastases from malignant melanoma is presented. These patients were treated with radiation therapy to a variety of total doses and dose fractions to investigate correlations between fraction size, total dose, and response rates with local control. This study showed a correlation between initial response rate and eventual local control with larger fraction sizes in cutaneous melanoma lesions.
RADICAL REIRRADIATIONFOR RECURRENTOR SECOND PRIMARY CARCINOMAOF THE FEMALE REPRODUCTIONTRACT Anthony H. Russell, M.D., Wui-Jin Koh, M.D., Katherine Markette, M.D., Kenneth J. Russell, M.D., Joanna M. Cain, M.D., Hisham K. Tamimi, M.D., Benjamin E. Greer, M.D., and David C. F&e, M.D. Department of Radiation Oncology and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA
Cancer, Supplement
to, Vol. 60, No. 3, August 1, 1987
This supplement covers the papers presented at the National Conference for Urologic Cancer- 1986 held in cooperation with the American Urological Association. It is worth your time to peruse the many topics covered.
(~ynecologic Oncology, Vol. 21, No. 2, June 1987, pp. 226-232 This article discusses the reirradiation of 25 patients who had recurrent or a second primary carcinoma of the female reproductive tract. The mean age of initial radiation was 49 years and the mean age of second irradiation was 64 years. The types of diagnosis, reirradiation techniques, and results of cancer control and complications are discussed. Patients most likely to have favorable outcomes are those that have second malignancies of small volume that are centrally located in the pelvis and are amenable to brachytherapy. Works by other people are also discussed to help put this information into perspective.
CIGARETTE SMOKING AND LEUKEMIA Richard K. Severson, Ph.D. Fred Hutchinson Cancer Research Center, Seattle, Washington, and Department of Epidemiology, Univ. of Washington, Seattle. WA Cancer, Vol. 60, No. 2, July 15, 1987, pp. 141-144 Presented is a preliminary study associating cigarette smoking with leukemia. A possible causal association has been found in the histologic subtype of adult AML and other acute nonlymphocytic leukemias. Additional studies and reanalysis of previous epidemologic studies of leukemia are needed yet to confirm (or refute) this hypothesis.
EFFECTSOF ROENTGEN IRRADIATIONON HUMAN MELANOMAMETASTASESIN THE SKIN R. Salmi and P. Holsti The Department of Radiotherapy and Oncology, Helsinki University Central Hospital, Helsinki, Finland ACTA Oncologica, Vol. 26 (1987) Fast. 1 pp. 37-40 Seventeen patients with a total of 36 skin metastases of malignant melanoma were treated with 500 cGy fraction size to varying total doses of 40 Gy, 60 Gy, and 80 Gy. This was done to study the morphologic effects of irradiation of melanoma metastases in vivo. 10 to 14 days after the tumors were irradiated, they were removed to study. Cellular and histologic alterations were investigated.
TEMPLATE-GUIDEDINTERSTITIALIMPLANTS:CS- 137 REUSABLESOURCES AS A SUBSTITUTE FOR IR- 192 Jeffrey F. Williamson,
Ph.D. and Thomas Seminoff, B.S.
Department of Radiation Oncology, University of Arizona and Radiation Therapy Resources, Inc., Valencia, CA Radiology, Vol. 165, No. 1, October 1987. pp. 265-269
MALIGNANT MELANOMA:ANALYSISOF DOSE FRACTIONATIONIN RADIATION THERAPY
This article presents the use of Cs- 137 as an economical and reusable alternative to using Ir- 192 for template-guided interstitial implants. The Cs-137 sources have an active length of 6.15 cm that are encapsulated near the distal end of a 21 cm long stainless steel tube. The diameter is only slightly larger than when using Ir-192. ( 1.9 and 1.7 mm, Cs-137, 1.5 mm, Ir-192). Discussed are radiation protection, cost effectiveness and the physical and dosimetric aspects of the sources as compared with Ir- 192.
John B. Konefal, M.D., Bahman Emami, M.D., and Miljenko V. Pilepich, M.D. Division of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO Radiology, Sept. 1987, Vol. 164, No. 3, pp. 607-610 37
0739-021 l/88 $3.00 + .OO Copyright 0 1988 American Association of Medical Dosimetrists
?? Literature Reviews BETH YANKE
A study of 35 patients with 67 measurable cutaneous or lymph node metastases from malignant melanoma is presented. These patients were treated with radiation therapy to a variety of total doses and dose fractions to investigate correlations between fraction size, total dose, and response rates with local control. This study showed a correlation between initial response rate and eventual local control with larger fraction sizes in cutaneous melanoma lesions.
RADICAL REIRRADIATIONFOR RECURRENTOR SECOND PRIMARY CARCINOMAOF THE FEMALE REPRODUCTIONTRACT Anthony H. Russell, M.D., Wui-Jin Koh, M.D., Katherine Markette, M.D., Kenneth J. Russell, M.D., Joanna M. Cain, M.D., Hisham K. Tamimi, M.D., Benjamin E. Greer, M.D., and David C. F&e, M.D. Department of Radiation Oncology and the Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA
Cancer, Supplement
to, Vol. 60, No. 3, August 1, 1987
This supplement covers the papers presented at the National Conference for Urologic Cancer- 1986 held in cooperation with the American Urological Association. It is worth your time to peruse the many topics covered.
(~ynecologic Oncology, Vol. 21, No. 2, June 1987, pp. 226-232 This article discusses the reirradiation of 25 patients who had recurrent or a second primary carcinoma of the female reproductive tract. The mean age of initial radiation was 49 years and the mean age of second irradiation was 64 years. The types of diagnosis, reirradiation techniques, and results of cancer control and complications are discussed. Patients most likely to have favorable outcomes are those that have second malignancies of small volume that are centrally located in the pelvis and are amenable to brachytherapy. Works by other people are also discussed to help put this information into perspective.
CIGARETTE SMOKING AND LEUKEMIA Richard K. Severson, Ph.D. Fred Hutchinson Cancer Research Center, Seattle, Washington, and Department of Epidemiology, Univ. of Washington, Seattle. WA Cancer, Vol. 60, No. 2, July 15, 1987, pp. 141-144 Presented is a preliminary study associating cigarette smoking with leukemia. A possible causal association has been found in the histologic subtype of adult AML and other acute nonlymphocytic leukemias. Additional studies and reanalysis of previous epidemologic studies of leukemia are needed yet to confirm (or refute) this hypothesis.
EFFECTSOF ROENTGEN IRRADIATIONON HUMAN MELANOMAMETASTASESIN THE SKIN R. Salmi and P. Holsti The Department of Radiotherapy and Oncology, Helsinki University Central Hospital, Helsinki, Finland ACTA Oncologica, Vol. 26 (1987) Fast. 1 pp. 37-40 Seventeen patients with a total of 36 skin metastases of malignant melanoma were treated with 500 cGy fraction size to varying total doses of 40 Gy, 60 Gy, and 80 Gy. This was done to study the morphologic effects of irradiation of melanoma metastases in vivo. 10 to 14 days after the tumors were irradiated, they were removed to study. Cellular and histologic alterations were investigated.
TEMPLATE-GUIDEDINTERSTITIALIMPLANTS:CS- 137 REUSABLESOURCES AS A SUBSTITUTE FOR IR- 192 Jeffrey F. Williamson,
Ph.D. and Thomas Seminoff, B.S.
Department of Radiation Oncology, University of Arizona and Radiation Therapy Resources, Inc., Valencia, CA Radiology, Vol. 165, No. 1, October 1987. pp. 265-269
MALIGNANT MELANOMA:ANALYSISOF DOSE FRACTIONATIONIN RADIATION THERAPY
This article presents the use of Cs- 137 as an economical and reusable alternative to using Ir- 192 for template-guided interstitial implants. The Cs-137 sources have an active length of 6.15 cm that are encapsulated near the distal end of a 21 cm long stainless steel tube. The diameter is only slightly larger than when using Ir-192. ( 1.9 and 1.7 mm, Cs-137, 1.5 mm, Ir-192). Discussed are radiation protection, cost effectiveness and the physical and dosimetric aspects of the sources as compared with Ir- 192.
John B. Konefal, M.D., Bahman Emami, M.D., and Miljenko V. Pilepich, M.D. Division of Radiation Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO Radiology, Sept. 1987, Vol. 164, No. 3, pp. 607-610 37