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Cardiac contusion: An experimental and pathologic study
377
ABSTRACTS Van Liere, Edward J., and Sleeth, Clark K.: nancy. Am. J. Physiol. 122: 34, 1938.
Cardiac Hypertrophy
During
Preg-
The normal heart weight-body weight ratio in 90 normal adult female guinea Twenty-six animals were killed within pigs was found to be 3.17 grams per kilogram. seventy-two hours after they had given birth to their young; the HTV/BTV ratio in these animals was found to be 3.06. Twenty-seven pregnant animals were killed during the latter part of pregnancy and the HW/BW ratio was found to be 2.93. Sfter the weight of the uterine contents had been subtracted from t.he body weight, however, the HW/BW ratio was found to be 3.17, that is, exactly the same as in the control animals. Corroborative data were also obtained from ten cats and seven dogs. The conclusions drawn from this work are: 1. Pregnancy does not cause cardiac hypertrophy in the guinea pig. (Nor was there any evidence of cardiac hypertrophy in 10 pregnant cats and 7 pregnant dogs.) 2. Since pregnancy does not produce cardiac hypertrophy in three different types of animals, it seems doubtful that it would produce it in human beings. 3. Increased tardiac work dots not necessarily produce cardiac hypertrophy. AUTIIOR.
Moritz, Alan R., and Atkins, Joseph P.: Cardiac Contusion: and Pathologic Study. Arch. Path. 25: 415, 1938.
An Experimental
The objective pathologic criteria for distinguishing between a cardiac contusion and a cardiac infarct vary in usefulness according to the age of the lesion. In the case of a recent myocardial lesion, the only evidence that should almost invariably serve to identify an otherwise indeterminate injury as an infarct is the finding of recent coronary occlusion. Pathologic changes more likely to be found in early contusion than in early infarction include massive interstitial hemorrhage, laceration, and tissue disorganization. Since all of these changes may be seen following spontaneous rupture of an early infarct, they are not conclusive. In the case of an older myocardial lesion there is no means of distinguishing objectively between contusion and infarction. Deposits of hemosiderin in myoeardial scars arc more likely to be seen in healed contusions than in healed infarcts, but, since hemosiderin is seen occasionally in healed infarcts, it,s presence is not conclusive. Three months after injury hemosiderin is found infrequently in traumatic scars, so that its absence in no way excludes the possibility of a lesion having been of traumat,ic origin. The presence or absence of remote coronary occlusion does not serve to identify a myocardial scar as having resulted from infarction or contusion, inasmuch as a heart which is the seat of occlusive coronary disease may have a superimposed traumatic lesion, and a heart with a large healed infarct may have no demonstrable c,oronary occlusion. The pathologic characteristics of the scars of myocardial c,ontusion and infarction are frequently identica1, and the presumptive nature of their origin must. be determined by historica data rather than by post-mortem examination.
Holbrook, Arthur A.: Normal Venous Pressure as Determined Am. J. M. SC. 196: 751,1938.
by a Direct Method.
Normal venous pressure values obtained by various direct methods are quoted from the literature. Venous pressures of 48 normal subjects determined according to the method of Griffith, Chamberlain, and Kitchel are presented in three tables. The first, series was studied with the test arm “extended by the side in supination.” In the second and
ABSTRACTS Van Liere, Edward J., and Sleeth, Clark K.: nancy. Am. J. Physiol. 122: 34, 1938.
Cardiac Hypertrophy
During
Preg-
The normal heart weight-body weight ratio in 90 normal adult female guinea Twenty-six animals were killed within pigs was found to be 3.17 grams per kilogram. seventy-two hours after they had given birth to their young; the HTV/BTV ratio in these animals was found to be 3.06. Twenty-seven pregnant animals were killed during the latter part of pregnancy and the HW/BW ratio was found to be 2.93. Sfter the weight of the uterine contents had been subtracted from t.he body weight, however, the HW/BW ratio was found to be 3.17, that is, exactly the same as in the control animals. Corroborative data were also obtained from ten cats and seven dogs. The conclusions drawn from this work are: 1. Pregnancy does not cause cardiac hypertrophy in the guinea pig. (Nor was there any evidence of cardiac hypertrophy in 10 pregnant cats and 7 pregnant dogs.) 2. Since pregnancy does not produce cardiac hypertrophy in three different types of animals, it seems doubtful that it would produce it in human beings. 3. Increased tardiac work dots not necessarily produce cardiac hypertrophy. AUTIIOR.
Moritz, Alan R., and Atkins, Joseph P.: Cardiac Contusion: and Pathologic Study. Arch. Path. 25: 415, 1938.
An Experimental
The objective pathologic criteria for distinguishing between a cardiac contusion and a cardiac infarct vary in usefulness according to the age of the lesion. In the case of a recent myocardial lesion, the only evidence that should almost invariably serve to identify an otherwise indeterminate injury as an infarct is the finding of recent coronary occlusion. Pathologic changes more likely to be found in early contusion than in early infarction include massive interstitial hemorrhage, laceration, and tissue disorganization. Since all of these changes may be seen following spontaneous rupture of an early infarct, they are not conclusive. In the case of an older myocardial lesion there is no means of distinguishing objectively between contusion and infarction. Deposits of hemosiderin in myoeardial scars arc more likely to be seen in healed contusions than in healed infarcts, but, since hemosiderin is seen occasionally in healed infarcts, it,s presence is not conclusive. Three months after injury hemosiderin is found infrequently in traumatic scars, so that its absence in no way excludes the possibility of a lesion having been of traumat,ic origin. The presence or absence of remote coronary occlusion does not serve to identify a myocardial scar as having resulted from infarction or contusion, inasmuch as a heart which is the seat of occlusive coronary disease may have a superimposed traumatic lesion, and a heart with a large healed infarct may have no demonstrable c,oronary occlusion. The pathologic characteristics of the scars of myocardial c,ontusion and infarction are frequently identica1, and the presumptive nature of their origin must. be determined by historica data rather than by post-mortem examination.
Holbrook, Arthur A.: Normal Venous Pressure as Determined Am. J. M. SC. 196: 751,1938.
by a Direct Method.
Normal venous pressure values obtained by various direct methods are quoted from the literature. Venous pressures of 48 normal subjects determined according to the method of Griffith, Chamberlain, and Kitchel are presented in three tables. The first, series was studied with the test arm “extended by the side in supination.” In the second and