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CAROTID 2D STRAIN IS A NEW ECHOCARDIOGRAPHIC MEASURE OF ARTERIAL STIFFNESS IN BOTH CONTROLS AND HYPERTENSIVES
E1154 JACC March 27, 2012 Volume 59, Issue 13
Imaging CAROTID 2D STRAIN IS A NEW ECHOCARDIOGRAPHIC MEASURE OF ARTERIAL STIFFNESS IN BOTH CONTROLS AND HYPERTENSIVES ACC Moderated Poster Contributions McCormick Place South, Hall A Saturday, March 24, 2012, 9:30 a.m.-10:30 a.m.
Session Title: Imaging: Echo Atherosclerosis and LV Mechanics Abstract Category: 22. Imaging: Echo Presentation Number: 1101-454 Authors: Kye Hun Kim, Donghan Kim, Ki Hong Lee, Hyun Ju Yoon, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Young Keun Ahn, Myung Ho Jeong, Jeong-Gwan Cho, Jong Chun Park, Jung Chaee Kang, Chonnam National University Hospital, Gwangju, South Korea Background: To investigate the usefulness of carotid strain measurement as a new echocardiographic measure of arterial stiffness. Methods: A total of 42 patients with newly diagnosed isolated hypertension (HT) and 20 normal controls were enrolled. Pulse wave velocity (PWV) and analysis (PWA) were used as standard measures of arterial stiffness. Circumferential strain (CS) of carotid artery was measured by 2D speckle tracking method. Results: CS was significantly decreased in hypertensives than in controls (4.2±2.0% vs 6.8±3.6%, p=0.001). Overall, CS showed significant negative correlation with age (r=-0.804, p<0.01), heart-femoral PWV (HFPWV, r=-0.576, p<0.01), brachial-ankle PWV (BAPWV, r=-0.614, p<0.01), augmentation index (AI, r=-0.581, p<0.01) and pressure (AP, r=-0.461, p<0.01), systolic blood pressure (SBP, r=-0.254, p<0.05), central SBP (r=-0.309, p<0.05), central pulse pressure (PP, r=-0.353, p<0.01). The comparisons of the correlation between CS and other parameters were summarized in the table. CS showed good correlation with age and PWV variables, but showed weak correlation with PWA variables. Conclusion: Carotid CS showed significant correlation with age and the parameters of arterial stiffness in both controls and hypertensives. PWV variables showed better correlation with CS than PWV variables. The present study suggested that CS would be a useful new measure of arterial stiffness. Table. The correlation between circumferential strain and other parameters
Age SBP HFPWV BAPWV AI AP Central SBP Central DBP Central PP
Controls (n=20) r value -0.859 -0.304 -0.458 -0.604 -0.738 -0.491 -0.412 -0.309 -0.363
p value <0.01 ns <0.01 <0.01 <0.01 <0.01 <0.05 ns p<0.05
Hypertensives (n=42) r value -0.742 -0.129 -0.593 -0.617 -0.382 -0.272 -0.326 -0.225 -0.206
p value <0.01 ns <0.01 <0.01 <0.05 ns ns ns ns
Imaging CAROTID 2D STRAIN IS A NEW ECHOCARDIOGRAPHIC MEASURE OF ARTERIAL STIFFNESS IN BOTH CONTROLS AND HYPERTENSIVES ACC Moderated Poster Contributions McCormick Place South, Hall A Saturday, March 24, 2012, 9:30 a.m.-10:30 a.m.
Session Title: Imaging: Echo Atherosclerosis and LV Mechanics Abstract Category: 22. Imaging: Echo Presentation Number: 1101-454 Authors: Kye Hun Kim, Donghan Kim, Ki Hong Lee, Hyun Ju Yoon, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Young Keun Ahn, Myung Ho Jeong, Jeong-Gwan Cho, Jong Chun Park, Jung Chaee Kang, Chonnam National University Hospital, Gwangju, South Korea Background: To investigate the usefulness of carotid strain measurement as a new echocardiographic measure of arterial stiffness. Methods: A total of 42 patients with newly diagnosed isolated hypertension (HT) and 20 normal controls were enrolled. Pulse wave velocity (PWV) and analysis (PWA) were used as standard measures of arterial stiffness. Circumferential strain (CS) of carotid artery was measured by 2D speckle tracking method. Results: CS was significantly decreased in hypertensives than in controls (4.2±2.0% vs 6.8±3.6%, p=0.001). Overall, CS showed significant negative correlation with age (r=-0.804, p<0.01), heart-femoral PWV (HFPWV, r=-0.576, p<0.01), brachial-ankle PWV (BAPWV, r=-0.614, p<0.01), augmentation index (AI, r=-0.581, p<0.01) and pressure (AP, r=-0.461, p<0.01), systolic blood pressure (SBP, r=-0.254, p<0.05), central SBP (r=-0.309, p<0.05), central pulse pressure (PP, r=-0.353, p<0.01). The comparisons of the correlation between CS and other parameters were summarized in the table. CS showed good correlation with age and PWV variables, but showed weak correlation with PWA variables. Conclusion: Carotid CS showed significant correlation with age and the parameters of arterial stiffness in both controls and hypertensives. PWV variables showed better correlation with CS than PWV variables. The present study suggested that CS would be a useful new measure of arterial stiffness. Table. The correlation between circumferential strain and other parameters
Age SBP HFPWV BAPWV AI AP Central SBP Central DBP Central PP
Controls (n=20) r value -0.859 -0.304 -0.458 -0.604 -0.738 -0.491 -0.412 -0.309 -0.363
p value <0.01 ns <0.01 <0.01 <0.01 <0.01 <0.05 ns p<0.05
Hypertensives (n=42) r value -0.742 -0.129 -0.593 -0.617 -0.382 -0.272 -0.326 -0.225 -0.206
p value <0.01 ns <0.01 <0.01 <0.05 ns ns ns ns