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Catalog of teratogenic agents
Toxicology Letters ELSEVIER
Toxicology
Letters 81 (1995) 79-83
Book reviews
Catalog of Teratogenic Agents, 8th Edition. Edited by T.H. Shepard, ‘The Johns Hopkins University Press, Baltimore, MD. 1995, 542 pp., $110.00.
Large gaps remain in teratology knowledge. Of the over 2500 agents contained in this catalog, approximately 1200 produce congenital anomalies in experimental animals, but only 40 are known to affect humans. Because teratology literature is not limited to a few specialized journals, this catalog was developed to link information on experimental teratogens with the congenital defects in humans and to provide a listing of available literature. It attempts to cover all drugs, chemicals, physical factors and viruses studied for teratogenicity in humans or animals, and includes a considerable number of nonteratogenic agents. This 8th edition has 1.500 additions, including 270 newly listed agents, alphabetical listings by work type in the occupational exposure listing, and defect syndromes caused by transgenic mutations listed by the affected organ. Tables of comparative periods of embryonic and fetal tissue development in humans and experimental animals, and of proven, possible and unlikely human teratogens are included. Listed alphabetically, main entries are followed by synonyms and brief accounts of some of the published works, such as species, dose, gestational age at ad.ministration and type of congenital defect displayed. Any human data is listed in the first part of the abstract. Listed references were chosen because of their review nature, originality or because they were most current; those added in the 7th or 8th editions have the publication year in bold type. Studies on species
phylogenetically below chicks were excluded, as were references solely on defect production mechanisms. Alternate chemical and proprietary names are cross-referenced within the text, in addition to extensive author and subject indices. Further reference volumes and databases are given in the preface. This publication will be invaluable in literature searches for teratologists, environmental and research scientists. Jennifer L. Howe
Comparative Toxicology Laboratories, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506-5606, USA.
SSDI 0378-4274(95)03454-S
Reproductive Effects of Chemical, Physical, and Biologic Agents: REPROTOX. Edited by A.R.
Scialli, A. Lione, G.K. Boyle Padgett (Eds.), The Johns Hopkins University Press, Baltimore, MD. 1995, 891 pp., $150.00. Do you have questions dealing with pregnancy exposures? Then this is the publication for you! This volume represents the print version of the REPROTOX database, begun by Dr Sergio Fabro as a computerized collection of his expert consultation letters for physicians and patients with pregnancy exposure questions. Brief summaries, which
Toxicology
Letters 81 (1995) 79-83
Book reviews
Catalog of Teratogenic Agents, 8th Edition. Edited by T.H. Shepard, ‘The Johns Hopkins University Press, Baltimore, MD. 1995, 542 pp., $110.00.
Large gaps remain in teratology knowledge. Of the over 2500 agents contained in this catalog, approximately 1200 produce congenital anomalies in experimental animals, but only 40 are known to affect humans. Because teratology literature is not limited to a few specialized journals, this catalog was developed to link information on experimental teratogens with the congenital defects in humans and to provide a listing of available literature. It attempts to cover all drugs, chemicals, physical factors and viruses studied for teratogenicity in humans or animals, and includes a considerable number of nonteratogenic agents. This 8th edition has 1.500 additions, including 270 newly listed agents, alphabetical listings by work type in the occupational exposure listing, and defect syndromes caused by transgenic mutations listed by the affected organ. Tables of comparative periods of embryonic and fetal tissue development in humans and experimental animals, and of proven, possible and unlikely human teratogens are included. Listed alphabetically, main entries are followed by synonyms and brief accounts of some of the published works, such as species, dose, gestational age at ad.ministration and type of congenital defect displayed. Any human data is listed in the first part of the abstract. Listed references were chosen because of their review nature, originality or because they were most current; those added in the 7th or 8th editions have the publication year in bold type. Studies on species
phylogenetically below chicks were excluded, as were references solely on defect production mechanisms. Alternate chemical and proprietary names are cross-referenced within the text, in addition to extensive author and subject indices. Further reference volumes and databases are given in the preface. This publication will be invaluable in literature searches for teratologists, environmental and research scientists. Jennifer L. Howe
Comparative Toxicology Laboratories, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506-5606, USA.
SSDI 0378-4274(95)03454-S
Reproductive Effects of Chemical, Physical, and Biologic Agents: REPROTOX. Edited by A.R.
Scialli, A. Lione, G.K. Boyle Padgett (Eds.), The Johns Hopkins University Press, Baltimore, MD. 1995, 891 pp., $150.00. Do you have questions dealing with pregnancy exposures? Then this is the publication for you! This volume represents the print version of the REPROTOX database, begun by Dr Sergio Fabro as a computerized collection of his expert consultation letters for physicians and patients with pregnancy exposure questions. Brief summaries, which