In?. .I. Biochem. Vol. 23, No. 12, pp. 1497-1499, Great Britain
1991
Pergamon Press plc.Printedin
BOOK REVIEWS
Protein Structure, Prediction and Design, Biochemical Society Symposium 40-Edited by J. KAY, G. LUNT and D. OXXITHORPE. 158pp. 1990. Portland Press, London. %80.
The topics discussed in this volume are: Compose-a rule-based approach to modelling protein structure; secondary structure prediction; inverting the protein-folding problem; ligand-specific transport proteins; receptor and channel structures; binding sites of the nicotinic AchR; monoamine neurotransmitter receptors; the expert system approach to protein structure; preparation of artificial bifunctional enzymes by gene fusion; restructuring catalysis in the mandelate pathway; identification of binding determinants; antibody combining sites. Enzyme Handbook 1, Class 4: Lyasea-Edited by D. SCHOMEWRG and M. SALZMANN.810 pp. 1990. Springer, Berlin. Loose-leaf binder, DM 248. This series of volumes provides the data on classified groups of enzymes. The sheets are arranged according to EC number. Each enzyme is given its systematic and common names, types of reactions, substrates, products, inhibitors, cofactors, kinetic data, pH, temperature range, origin, purification, molecular data, storage conditions, and crossreference to structure data banks (PIR/MIPS code). Further literature references to that enzyme are given. A very useful systematic source of information. Cell Culture for Biochemists, 2nd edn-R. L. P. ADAMS.364 pp. 1990. Elsevier, Amsterdam. D.Fl. 87. Cell cultures are becoming increasingly important in research and could one day replace 50% of animal experiments. This new edition describes the characteristics of cultured cells; culture vessels; subculturing; cell culture media; primary cells (lymphocytes, human skin, mouse embryo cultures, chick embryo cultures, rat hepatocytes, kidney cells, endothelial cells, epithelial cells, colonic cells, muscle cells, macrophages, ascites cells, dipteran cells); techniques; glassware preparation and sterilization; contamination; cell cycle; cell synchronization; use of radioisotopes; cell mutants and hybrids; viruses; differentiation in cell culture; media formulation. Plant Lipid Biochemistry, Structure and Utlllzntio~Edited by P. J. QUINNand J. L. HARWOOD.483 pp. 1990. Portland
Press, London. $95. This is the Proceedings of the 9th International Congress on Plant Lipids. The main sections are on: lipid structure and analysis; physical properties of membrane lipids; role of lipids in membranes; fatty acid synthesis; acyl thioesterases and acyltransferases; triacylglycerol formation; polar lipid synthesis and translocation; catabolism of lipids; sterols and terpenoids; modulation of lipid turnover; effects of light and temperature; herbicides and pathological changes in plant lipids; molecular biology and biotechnology. Parallels in CeU to Cell Junctions in Plants and Animals. NATO ASI Series H. Cell Biology, Vol. 46-Edited by
The cell-to-cell junctions in plants (plasmodesmata) and animals (gap junctions) allow molecules of similar size to pass, and some proteins in the plasmodesmata cross-react immunologically with those in gap junctions. This book reviews the role of these junctions as a gating mechanism controlling communication and function between cells in plants and animals. The Cytoskeleton and Cell Motility-T. M. PRFsT0N,C. A. KING and J. S. HYAMS.202 pp. 1990. Blackie/Chapman & Hall, London. U.S.A. $69.95 cloth, $29.50 paperback. Elsewhere S83.95 cloth, $35.50 paperback. The last 10 years have seen tremendous advances in our understanding of cell motility, cellular organization and control of movements within cells. This book describes the molecular components of the cytoskeleton (actin, actinbinding proteins, myosin, microtubules, intermediate filaments, tektins, lamins); movement within cells (axonal transport, protozoan intracellular motility, movement of pigment cells, plant cytoplasmic streaming); mitosis; cilia and flagella; crawling movements; cell surface motility; contractile phenomena. A very interesting and useful book. Nutrition;
Proteins
and Ammo Acids-Edited
by A.
YOSHIDA,H. NAITQ Y. NIIYAMA and T. SUZUKI. 327 pp.
1990. Japanese Scientific Societies Press/Springer S87.10.
Berlin.
The general availability of a wide range of foods has increased, and this together with increased wealth has brought about nutritional changes in Japan. These are surveyed and summarized in the present book. There is a historical introduction and the main chapters deal with protein metabolism; proteins and amino acids requirements; physiological aspects of proteins and amino acids; nutritional aspects of food proteins; clinical aspects of amino acids (hepatic encephalopathy, chronic renal failure); uses of amino acids in parental and enteral nutrition, in medicine and general nutrition; production of amino acids. Activation
and Desenaitisatioa
of Tramking
Pathways.
NATO AS1 Series H. CeU Biology, Vol. 44--Edited by T. M. KONIJN,M. D. HOUSLAYand P. J. M. VANHAASTERT.320 pp. 1990. Springer, Berlin. DM 188. Many transducing pathways involve second messenger systems. This book considers those involved in chemotaxis and chemosensing; cyclic nucleotide coupled systems (ghtcagon, luteinizing hormone, protein kinase); inositol phospholipid coupled systems (insulin, purinergic linked phospholipase C); G protein activation; cGMP phosphodiesterase in retinal rods; auxin-coupled systems; regulation of the desensitization of the nicotinic AChR, thyroid function; neuronal secretion. These systems allow greater control and increase/decrease of the amplification processes in transduction. Progrsmmed CeU Death in Tumours and Thuea-I. D. &W-EN and S. M. BowEN. 268 pp. 1990. Chapman & Hall,
London. U.S.A. $85. Elsewhere $102.
A. W. ROBARDS,W. J. Luclls, J. D. Prrrs, H. J. JONGSMA Cell death can be genetically programmed or be caused by and D. C. SPRAY.283 pp. 1990. Springer, Berlin. DM 178. accident and injury. Various enzymes such as hydrolases,
Bc23112-K
1497