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CENTENARY OF THE LANCET.
955 The work was, however, interrupted by my departurefrom that town, and, unfortunately, the number of cases studied was not extensive enough to justify us recording our results. But so far as our investigation went we observed that the infected guinea-pigs which had received the tubercle vaccine survived longerthan those which had not, and that the vaccine could be administered to a greater variety of clinical cases. of tuberculosis and in much larger doses. The superiority of this lipoid-free antigen over otherforms of tubercle antigens is also indicated in the work on the complement-fixation test for tuberculosis independently conducted by Seller and Ramsbottom.I has yet to be done to establish the Although much " value of any defatted " tubercle vaccine as a therapeutic remedy, I believe as I did that a tubercle antigen, when free from lipoids, is more readily emulsified and more favourable to interaction with its antibody, in vivo and in vitro. I am therefore the more glad to see Prof. Dreyer’s research on the subject, and await his further results with much
Correspondence. " Audi alteram partem."
CENTENARY OF THE LANCET.
To the Editor of THE LANCET. SIR,-I should like to add a congratulatory message to the many you have received on the Centenary of THE LANCET. I am the proud possessor of the first volume of THE LANCET, which belonged to my great grandfather, and bears on the fly-leaf the bookplate, " Thomas Steele, Surgeon, Reigate, Surrey." At his death it passed with a number of other early volumes of THE LANCET to my grandfather, John Sisson Steele, M.R.C.S., L.S.A., of Reigate. I myself inherited these volumes from my father, Dr. Russell Steele, of Hemel Hempstead. Though, alas, several volumes have disappeared since moving from one house to another, I am still the lucky and proud interest.-I am, Sir, yours faithfully, C. Y. WANG, M.D., F.R.C.P. Edin. possessor of Volume No. 1. I am, Sir, yours faithfully, University of Hong-Kong, Sept. 15th, 1923. RUSSELL V. STEELE, M.B., B.S. Haverhill, Suffolk, Oct. 19th, 1923. THE RELATION OF GASTRIC ULCER TO
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CARCINOMA. WARDROP’S OPERATION. To the Editor of THE LANCET.
To the Editor of THE LANCET. SIR,-In connexion with a paper on the aboveSIR,—In the very interesting Centenary Number of subject that appeared in your issue of Oct. 13th I THE LANCET it is stated on p. 696 that the name of should like to mention that for over two years a. James Wardrop " may still be familiar from its special sub-committee of the Pathological Society of occurrence in some text-books as the originator of Manchester, with Dr. J. H. Dible, lecturer in pathothe treatment of aneurysm by distal ligature." logy at the University, as secretary, has been collecting I think that Brasdor was the first to suggest distal pathological material bearing on the relation of ligature of the trunk of the artery affected by the gastric ulcer and cancer. This collection, in which. aneurysm. He did not himself perform the operation, the specimens dealt with in my paper are included,nor did it meet with success at the hands of others along with those of several colleagues and some for many years. Wardrop was the first to perform the obtained at autopsies, provides a body of material operation with success, ligaturing the carotid artery on which it will, I hope, be possible to base a much on the distal side of an aneurysm of that trunk. Thismore comprehensive study of the problem than the was in 1825. It was, I think, with the object of cases of an individual surgeon can afford. The giving effect to the two-fold principle of the Hunterian existence of this committee and my indebtedness. operation that Wardrop subsequently suggested to it, and through it to the department of pathology of ligature either of the carotid or subclavian artery forthe Manchester University, were referred to in my the cure of aneurysm of the innominate. He hoped to’ paper as read before the Manchester Surgical Society,,,have a healthy portion of vessel with which to dealbut omitted from the copy sent for publication, as and he desired to lessen rather than to arrest the being rather of local than general interest. On furtherflow of blood through the sac. consideration, however, I regret this omission, and I have not looked up the original records, and I am would ask you to allow me to correct it. writing from my recollections of the lectures of the’ I am, Sir, yours faithfully, late Prof. Pirrie, of Aberdeen, of 43 years ago. He JOHN MORLEY Manchester, Oct. 21st, 1923. always insisted on defining Brasdor’s operation as ligature of the trunk of the artery affected and close X RAY DIAGNOSIS OF PREGNANCY: ITS to the aneurysm, and Wardrop’s operation as ligature MEDICO-LEGAL ASPECT. of a distal branch. I am, Sir, yours faithfully, To the Editor of THE LANCET. T. WARDROP GRIFFITH. Leeds, Oct. 16th, 1923. SIR,—The annotation in your issue of Oct. 20th,. commenting upon the decision of the French law courts in l’affaire d’Evreux, has interested me very "DEFATTED" TUBERCLE ANTIGENS. much because I have been investigating for overTo the Editor of THE LANCET. 12 months the value of X rays as an aid in the diagnosis " SIR,-Prof. Dreyer’s article on defatted " antigens of pregnancy at different stages. By the employwhich appeared in the June number of the British ment of the correct technique it is my opinion that theJournal of Experimental Pathology, and to which fcetal skeleton can be clearly demonstrated upon a reference had been made in recent issues of your skiagram with absolute certainty in any case during: journal, has given me more than usual interest, in or after the sixth month of pregnancy. Earlier thanthat the line of his investigation corresponds some- this it is more difficult but not by any means impossible, what closely to that which I had pursued some years the difficulty, of course, increasing the earlier the back. With a tubercle antigen freed from fat by stage of pregnancy. I have recently succeeded in repeated treatment with ether and chloroform I had proving pregnancy by the demonstration of the carried out a series of tests on the complement-fixation foetal skeleton on a skiagram in a case which was method for tuberculosis, and published my resultsl estimated to be about three and a half months’ in which the technique on the preparation of the fat- gestation. An article which I have written on the free antigen was described. The specific reaction subject of Radiography of the Fcetus in Utero, with which I had obtained in the test had induced me to illustrations, is appearing in the October issue of the try it as a vaccine on tubercle infected guinea-pigs, Archives of Radiology and Electrology. I am of opinion, though, that the judgment for the and, later, with the kind cooperation of Dr. Guy and Dr. Elder, of Edinburgh, on tuberculous patients. plaintiff against the French surgeon, who failed ta 1 Brit. Med. Jour., July 5th, 1919. 2 Jour. Path. and Bacteriol., 1922, xxv., 247. ,
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Correspondence. " Audi alteram partem."
CENTENARY OF THE LANCET.
To the Editor of THE LANCET. SIR,-I should like to add a congratulatory message to the many you have received on the Centenary of THE LANCET. I am the proud possessor of the first volume of THE LANCET, which belonged to my great grandfather, and bears on the fly-leaf the bookplate, " Thomas Steele, Surgeon, Reigate, Surrey." At his death it passed with a number of other early volumes of THE LANCET to my grandfather, John Sisson Steele, M.R.C.S., L.S.A., of Reigate. I myself inherited these volumes from my father, Dr. Russell Steele, of Hemel Hempstead. Though, alas, several volumes have disappeared since moving from one house to another, I am still the lucky and proud interest.-I am, Sir, yours faithfully, C. Y. WANG, M.D., F.R.C.P. Edin. possessor of Volume No. 1. I am, Sir, yours faithfully, University of Hong-Kong, Sept. 15th, 1923. RUSSELL V. STEELE, M.B., B.S. Haverhill, Suffolk, Oct. 19th, 1923. THE RELATION OF GASTRIC ULCER TO
I
CARCINOMA. WARDROP’S OPERATION. To the Editor of THE LANCET.
To the Editor of THE LANCET. SIR,-In connexion with a paper on the aboveSIR,—In the very interesting Centenary Number of subject that appeared in your issue of Oct. 13th I THE LANCET it is stated on p. 696 that the name of should like to mention that for over two years a. James Wardrop " may still be familiar from its special sub-committee of the Pathological Society of occurrence in some text-books as the originator of Manchester, with Dr. J. H. Dible, lecturer in pathothe treatment of aneurysm by distal ligature." logy at the University, as secretary, has been collecting I think that Brasdor was the first to suggest distal pathological material bearing on the relation of ligature of the trunk of the artery affected by the gastric ulcer and cancer. This collection, in which. aneurysm. He did not himself perform the operation, the specimens dealt with in my paper are included,nor did it meet with success at the hands of others along with those of several colleagues and some for many years. Wardrop was the first to perform the obtained at autopsies, provides a body of material operation with success, ligaturing the carotid artery on which it will, I hope, be possible to base a much on the distal side of an aneurysm of that trunk. Thismore comprehensive study of the problem than the was in 1825. It was, I think, with the object of cases of an individual surgeon can afford. The giving effect to the two-fold principle of the Hunterian existence of this committee and my indebtedness. operation that Wardrop subsequently suggested to it, and through it to the department of pathology of ligature either of the carotid or subclavian artery forthe Manchester University, were referred to in my the cure of aneurysm of the innominate. He hoped to’ paper as read before the Manchester Surgical Society,,,have a healthy portion of vessel with which to dealbut omitted from the copy sent for publication, as and he desired to lessen rather than to arrest the being rather of local than general interest. On furtherflow of blood through the sac. consideration, however, I regret this omission, and I have not looked up the original records, and I am would ask you to allow me to correct it. writing from my recollections of the lectures of the’ I am, Sir, yours faithfully, late Prof. Pirrie, of Aberdeen, of 43 years ago. He JOHN MORLEY Manchester, Oct. 21st, 1923. always insisted on defining Brasdor’s operation as ligature of the trunk of the artery affected and close X RAY DIAGNOSIS OF PREGNANCY: ITS to the aneurysm, and Wardrop’s operation as ligature MEDICO-LEGAL ASPECT. of a distal branch. I am, Sir, yours faithfully, To the Editor of THE LANCET. T. WARDROP GRIFFITH. Leeds, Oct. 16th, 1923. SIR,—The annotation in your issue of Oct. 20th,. commenting upon the decision of the French law courts in l’affaire d’Evreux, has interested me very "DEFATTED" TUBERCLE ANTIGENS. much because I have been investigating for overTo the Editor of THE LANCET. 12 months the value of X rays as an aid in the diagnosis " SIR,-Prof. Dreyer’s article on defatted " antigens of pregnancy at different stages. By the employwhich appeared in the June number of the British ment of the correct technique it is my opinion that theJournal of Experimental Pathology, and to which fcetal skeleton can be clearly demonstrated upon a reference had been made in recent issues of your skiagram with absolute certainty in any case during: journal, has given me more than usual interest, in or after the sixth month of pregnancy. Earlier thanthat the line of his investigation corresponds some- this it is more difficult but not by any means impossible, what closely to that which I had pursued some years the difficulty, of course, increasing the earlier the back. With a tubercle antigen freed from fat by stage of pregnancy. I have recently succeeded in repeated treatment with ether and chloroform I had proving pregnancy by the demonstration of the carried out a series of tests on the complement-fixation foetal skeleton on a skiagram in a case which was method for tuberculosis, and published my resultsl estimated to be about three and a half months’ in which the technique on the preparation of the fat- gestation. An article which I have written on the free antigen was described. The specific reaction subject of Radiography of the Fcetus in Utero, with which I had obtained in the test had induced me to illustrations, is appearing in the October issue of the try it as a vaccine on tubercle infected guinea-pigs, Archives of Radiology and Electrology. I am of opinion, though, that the judgment for the and, later, with the kind cooperation of Dr. Guy and Dr. Elder, of Edinburgh, on tuberculous patients. plaintiff against the French surgeon, who failed ta 1 Brit. Med. Jour., July 5th, 1919. 2 Jour. Path. and Bacteriol., 1922, xxv., 247. ,
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