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Central giant cell granuloma in a child - case report
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Abstracts
and palate. The patient underwent an incisional biopsy and the microscopic features showed granulomatous inflammation with multinucleated giant cells containing fungal structures with an uncommon appearance. Periodic acid-Schiff and Groccott stains highlighted numerous large hyphae. A broad list of clinic and microscopic differential diagnosis was considered.
CENTRAL GIANT CELL GRANULOMA IN A CHILD CASE REPORT Farias AC1, Beder C1, Paiva K1, Melo Jr. EJM1, Ferreira SMS1, Franco AVM1 - 1CENTRO DE ESTUDOS SUPERIORES DE MACEIÓ - ODONTOLOGIA The Central giant cell granuloma (CGCG) has been classified as a rarely aggressive idiopathic benign intraosseous lesion. It occurs most frequently in young women (aged ⬍30 y) and mandible. In young and child differential diagnosis has to be made with other osteolytic neoformations of the jaws. This case reports a CGCG in a female child, 7-years- old, presented to the oral medicine clinic for evaluation of a tumor in her mouth. The lesion had been present for six months, painless, on the left inferior alveolar area, with a gradual increase in size. The clinical examination showed a pigmented nodule, painless, hard, not bleeding on the left lower gingival. A CT scan showed multilocular hypodense lesion on the mandibular symphysis, with cortical expansion, well-defined limits, from right canine to left canine tooth. The clinical, laboratory, histopathologic and diagnostic imaging exams determined the diagnosis.
IMPACT OF ORAL HEALTH ON THE QUALITY OF LIFE AMONG WOMEN LIVING WITH HIV/AIDS- A CROSSSECTIONAL STUDY IN MACEIO, NORTHEASTERN BRAZIL Lima ALO1, Albuquerque VWT1, Silva JIBW1, Ferreira SMS1, Peixoto FB, Meeks VI2 - 1CENTRO UNIVERSITÁRIO CESMAC, 2UNIVERSITY OF MARYLAND Objective: To analyze the self-reported oral health and oral health-quality of life (OHRQOL) among women living with HIV/AIDS. Methods: A cross-sectional study was conducted on a random sample using a questionnaire regarding socio-demographics and perception of oral health impact profile (OHIP-14). All data was analyzed using SPSS for Windows, version 17. Results: 108 women were interviewed; median age, 36 years; the majority living in urban centers (84.3%) with low income (70.4%), and without defined employment (93.5%). 38.9% of the women self-reported their oral health as fair. The OHRQOL was perceived moderately (OHIP-14 total Mean 13.19 ⫾ 10.56). The greater perceived impact was psychological distress (2.79 ⫾ 2.52). Subjects reporting oral health problems had a greater impact on their quality of life (p ⬍0.05). Conclusion: This study reinforces the need to include measures of the quality of life’s impact on oral health when planning programs in dentistry for people living with HIV.
METASTATIC BREAST CARCINOMA AFFECTING THE ZYGOMATIC BONE IN A YOUNG PATIENT Ribeiro ACP, Rosa GAB, Gouvêa AF1, Santos-Silva AR2, Medeiros RSS3, Dias RB4, Brandão TB1 - 1INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO - ICESP - SERVIÇO DE ODONTOLOGIA ONCOLÓGICA, 2FACULDADE DE ODONTOLOGIA DE PIRACICABA - FOP/UNICAMP - DEPARTAMENTO DE DIAGNÓSTICO ORAL, 3INSTITUTO
October 2012 DO CÂNCER DO ESTADO DE SÃO PAULO - ICESP, 4 FACULDADE DE ODONTOLOGIA DA USP - DEPARTAMENTO DE CIRURGIA, PRÓTESE E TRAUMATOLOGIA MAXILOFACIAIS This presentation reports the case of a 38-year-old female patient who was referred to our Clinic for evaluation of “dental abscess”. Her recent medical history included radical mastectomy due to an invasive metaplastic carcinoma of the left breast. Moderate asymmetry was observed in the right zygomatic area. Intraoral examination revealed periodontal disease, caries and residual roots. Diagnostic hypothesis included dental abscess and metastatic carcinoma. Head and neck computed tomography revealed wide zygomatic bone erosion and infiltration of the masseter muscle. Incisional biopsy demonstrated islands of atypical squamous cell. Further immunohistochemical analysis showed positivity for AE1/AE3, p63, EGFR and negativity for Cerb-b2, estrogen and progesterone, this immune profile was similar to the primary breast tumor. Thus, a diagnosis of metastatic breast carcinoma was rendered. Metastatic tumours to the maxillofacial region are rare and usually represent poor prognosis. The patient is being treated with combined chemoradiotherapy with partial control of the zygomatic lesion.
SIALADENOMA PAPILIFERUM: CASE REPORT Omena ALCS1, Carvalho KCS1, Ferreira SMS1, Silva AA2, Vargas PA2, Ribeiro CMB1 - 1CENTRO UNIVERSITÁRIO CESMAC, 2 UNICAMP - FACULDADE DE ODONTOLOGIA DE PIRACICABA Sialadenoma papiliferum (SP) is a rare benign neoplasia of salivary glands. Commonly it affects males older than 50 years, occurring in hard palate and oral mucosa. Clinically it is observed an exophytic papilar surface and asymptomatic lesion. This study reports a case of SP occurred in a female patient MJSS, 81 years-old, ex-smoker, complete denture prosthesis user. Who was referred to dentistry and presenting a nodule located in the hard palate during 60 years, reddish, 2x1x1cm, verrucous surface, irregular format, sessile, bleeding and painful due to prosthesis trauma. Clinical diagnostic hypothesis was pyogenic Granuloma. Excisional biopsy was conducted and microscopic analysis revealed benign neoplasia of salivary glands with solid cystic areas, spaces similar to ducts with a layer of oncocyte cells and other layer of basal cells and a stroma with lymphoid tissue. Histopathological diagnostic was SP and no recurrence of the lesion was observed in 6 months follow-up.
GINGIVAL OVERGROWTH INDUCED BY DRUGS AND IDIOPATHIC GINGIVAL FIBROMATOSIS: SIMILARITIES ASSOCIATED WITH PCNA AND 〈-SMA IMMUNOEXPRESSIONS Andrade ALDL1, Leão LV2, Galvão HC1, Rosa MRD3, Bonan PRF4 - 1UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE - PROGRAMA DE PÓS-GRADUAÇÃO EM PATOLOGIA ORAL, 2UNIVERSIDADE FEDERAL DOS VALES DO JEQUITINHONHA E MUCURI, 3UNIVERSIDADE FEDERAL DA PARAÍBA - DEPARTAMENTO DE CLÍNICA E ODONTOLOGIA SOCIAL, 4 UNIVERSIDADE FEDERAL DA PARAÍBA - DEPARTAMENTO DE ODONTOLOGIA CLÍNICA E SOCIAL Background/objectives: This study aimed to compare the Gingival Overgrowth Induced by Drugs (GOID) and Idiopathic Gengival Fibromatosis (IGF) according with PCNA and ␣-SMA immunoexpressions and with epithelial thickness.
e44
Abstracts
and palate. The patient underwent an incisional biopsy and the microscopic features showed granulomatous inflammation with multinucleated giant cells containing fungal structures with an uncommon appearance. Periodic acid-Schiff and Groccott stains highlighted numerous large hyphae. A broad list of clinic and microscopic differential diagnosis was considered.
CENTRAL GIANT CELL GRANULOMA IN A CHILD CASE REPORT Farias AC1, Beder C1, Paiva K1, Melo Jr. EJM1, Ferreira SMS1, Franco AVM1 - 1CENTRO DE ESTUDOS SUPERIORES DE MACEIÓ - ODONTOLOGIA The Central giant cell granuloma (CGCG) has been classified as a rarely aggressive idiopathic benign intraosseous lesion. It occurs most frequently in young women (aged ⬍30 y) and mandible. In young and child differential diagnosis has to be made with other osteolytic neoformations of the jaws. This case reports a CGCG in a female child, 7-years- old, presented to the oral medicine clinic for evaluation of a tumor in her mouth. The lesion had been present for six months, painless, on the left inferior alveolar area, with a gradual increase in size. The clinical examination showed a pigmented nodule, painless, hard, not bleeding on the left lower gingival. A CT scan showed multilocular hypodense lesion on the mandibular symphysis, with cortical expansion, well-defined limits, from right canine to left canine tooth. The clinical, laboratory, histopathologic and diagnostic imaging exams determined the diagnosis.
IMPACT OF ORAL HEALTH ON THE QUALITY OF LIFE AMONG WOMEN LIVING WITH HIV/AIDS- A CROSSSECTIONAL STUDY IN MACEIO, NORTHEASTERN BRAZIL Lima ALO1, Albuquerque VWT1, Silva JIBW1, Ferreira SMS1, Peixoto FB, Meeks VI2 - 1CENTRO UNIVERSITÁRIO CESMAC, 2UNIVERSITY OF MARYLAND Objective: To analyze the self-reported oral health and oral health-quality of life (OHRQOL) among women living with HIV/AIDS. Methods: A cross-sectional study was conducted on a random sample using a questionnaire regarding socio-demographics and perception of oral health impact profile (OHIP-14). All data was analyzed using SPSS for Windows, version 17. Results: 108 women were interviewed; median age, 36 years; the majority living in urban centers (84.3%) with low income (70.4%), and without defined employment (93.5%). 38.9% of the women self-reported their oral health as fair. The OHRQOL was perceived moderately (OHIP-14 total Mean 13.19 ⫾ 10.56). The greater perceived impact was psychological distress (2.79 ⫾ 2.52). Subjects reporting oral health problems had a greater impact on their quality of life (p ⬍0.05). Conclusion: This study reinforces the need to include measures of the quality of life’s impact on oral health when planning programs in dentistry for people living with HIV.
METASTATIC BREAST CARCINOMA AFFECTING THE ZYGOMATIC BONE IN A YOUNG PATIENT Ribeiro ACP, Rosa GAB, Gouvêa AF1, Santos-Silva AR2, Medeiros RSS3, Dias RB4, Brandão TB1 - 1INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO - ICESP - SERVIÇO DE ODONTOLOGIA ONCOLÓGICA, 2FACULDADE DE ODONTOLOGIA DE PIRACICABA - FOP/UNICAMP - DEPARTAMENTO DE DIAGNÓSTICO ORAL, 3INSTITUTO
October 2012 DO CÂNCER DO ESTADO DE SÃO PAULO - ICESP, 4 FACULDADE DE ODONTOLOGIA DA USP - DEPARTAMENTO DE CIRURGIA, PRÓTESE E TRAUMATOLOGIA MAXILOFACIAIS This presentation reports the case of a 38-year-old female patient who was referred to our Clinic for evaluation of “dental abscess”. Her recent medical history included radical mastectomy due to an invasive metaplastic carcinoma of the left breast. Moderate asymmetry was observed in the right zygomatic area. Intraoral examination revealed periodontal disease, caries and residual roots. Diagnostic hypothesis included dental abscess and metastatic carcinoma. Head and neck computed tomography revealed wide zygomatic bone erosion and infiltration of the masseter muscle. Incisional biopsy demonstrated islands of atypical squamous cell. Further immunohistochemical analysis showed positivity for AE1/AE3, p63, EGFR and negativity for Cerb-b2, estrogen and progesterone, this immune profile was similar to the primary breast tumor. Thus, a diagnosis of metastatic breast carcinoma was rendered. Metastatic tumours to the maxillofacial region are rare and usually represent poor prognosis. The patient is being treated with combined chemoradiotherapy with partial control of the zygomatic lesion.
SIALADENOMA PAPILIFERUM: CASE REPORT Omena ALCS1, Carvalho KCS1, Ferreira SMS1, Silva AA2, Vargas PA2, Ribeiro CMB1 - 1CENTRO UNIVERSITÁRIO CESMAC, 2 UNICAMP - FACULDADE DE ODONTOLOGIA DE PIRACICABA Sialadenoma papiliferum (SP) is a rare benign neoplasia of salivary glands. Commonly it affects males older than 50 years, occurring in hard palate and oral mucosa. Clinically it is observed an exophytic papilar surface and asymptomatic lesion. This study reports a case of SP occurred in a female patient MJSS, 81 years-old, ex-smoker, complete denture prosthesis user. Who was referred to dentistry and presenting a nodule located in the hard palate during 60 years, reddish, 2x1x1cm, verrucous surface, irregular format, sessile, bleeding and painful due to prosthesis trauma. Clinical diagnostic hypothesis was pyogenic Granuloma. Excisional biopsy was conducted and microscopic analysis revealed benign neoplasia of salivary glands with solid cystic areas, spaces similar to ducts with a layer of oncocyte cells and other layer of basal cells and a stroma with lymphoid tissue. Histopathological diagnostic was SP and no recurrence of the lesion was observed in 6 months follow-up.
GINGIVAL OVERGROWTH INDUCED BY DRUGS AND IDIOPATHIC GINGIVAL FIBROMATOSIS: SIMILARITIES ASSOCIATED WITH PCNA AND 〈-SMA IMMUNOEXPRESSIONS Andrade ALDL1, Leão LV2, Galvão HC1, Rosa MRD3, Bonan PRF4 - 1UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE - PROGRAMA DE PÓS-GRADUAÇÃO EM PATOLOGIA ORAL, 2UNIVERSIDADE FEDERAL DOS VALES DO JEQUITINHONHA E MUCURI, 3UNIVERSIDADE FEDERAL DA PARAÍBA - DEPARTAMENTO DE CLÍNICA E ODONTOLOGIA SOCIAL, 4 UNIVERSIDADE FEDERAL DA PARAÍBA - DEPARTAMENTO DE ODONTOLOGIA CLÍNICA E SOCIAL Background/objectives: This study aimed to compare the Gingival Overgrowth Induced by Drugs (GOID) and Idiopathic Gengival Fibromatosis (IGF) according with PCNA and ␣-SMA immunoexpressions and with epithelial thickness.