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Centrifuges reduce processing times
News and Views
Benchtop system offered AInicon h a s i n t r o d u c e d the P r o F l u x M30 s a n i t a r y b e n c h t o p m e m b r a n e filtration s y s t e m d e s i g n e d for r a p i d concentration, p u r i f i c a t i o n or d e s a l t i n g of biological s o l u t i o n s . Specific a p p l i c a t i o n s i n c l u d e r e s e a r c h a n d d e v e l o p m e n t , s c a l e - u p or the p r o d u c t i o n of b i o p h a r m a c e u t i c a l s . P r o F l u x M30 offers the u s e r a choice of t a n g e n t i a l u l t r a f i l t r a t l o n or m i c r o f i l t r a t i o n with spiral, hollow fibre or a n y c a s s e t t e type filtration cartridges. The c o m p a c t s y s t e m f e a t u r e s a CIP reservoir u n i t a n d a n e x p a n d a b l e c a r t r i d g e manifold. D a t a a c q u i s i t i o n ls offered for r e p o r t i n g a n d historical t r e n d i n g o n a PC. For f u r t h e r information contact: Amlcon Inc, 72 Cherry Hill l)rlw:, Beverley, MA 01915, USA. Tel: +1 508 777 3 6 2 2 , f a x : +1 508 777 6204.
Ionics secures c o n t r a c t s in t h e Far E a s t Ionlcs Inc h a s a n n o u n c e d t h a t it h a s s e c u r e d c o n t r a c t s totalling 8 2 . 6 m i l l i o n to s u p p l y w a t e r t r e a t m e n t e q u i p m e n t for i n d u s t r i a l p r o j e c t s i n the Far East. The first r e q u i r e s e q u i p m e n t to t r e a t boiler feed w a t e r for a T a i w a n - b a s e d oii refinery. The s e c o n d covers the t r e a t m e n t of p r o c e s s w a t e r at S o u t h Korea's t h i r d largest a u t o m o b i l e m a n u f a c t u r e r , Kia Motors. Both s y s t e m s will u s e I o n i c s ' p r o p r i e t a r y electrodlalysis r e v e r s a l (EDR) technology. F u r t h e r n e w s r e v e a l s t h a t Ionlcs h a s r e p o r t e d record r e v e n u e s , for the q u a r t e r a n d s l x - m o n t h period e n d e d 30 J u n e . For the q u a r t e r , r e v e n u e s of 8 5 6 . 5 m i l l i o n were u p 13.5 % c o m p a r e d with the s a m e period i n 1994, while n e t i n c o m e of $ 4 . 6 m i l l i o n a n d e a r n i n g s per s h a r e of $ 0 . 3 2 were u p 28.9 % a n d 28.0 % respectively. For the first half, r e v e n u e s of $ 1 1 3 . 4 m i l l i o n were u p 10.3 % c o m p a r e d w i t h the first h a l f of 1994, while n e t i n c o m e of $8.7 m i l l i o n a n d e a r n i n g s per s h a r e of S0.61 were u p 25.3 % a n d 24.5 % respectively. The c o m p a n y believes t h a t the m a l o r factors c o n t r i b u t i n g to its r e c o r d r e s u l t s were i m p r o v e d p e r f o r m a n c e i n the c a p i t a l e q u i p m e n t b u s i n e s s a n d c o n t i n u e d s t r e n g t h i n the u l t r a p u r e w a t e r b u s i n e s s s e r v i n g the s e m i c o n d u c t o r indusi~ry. For f u r t h e r information contact: lonlcs Inc, PO Box 9131, Watertown, MA 02272-9131, USA. Tel: +I 61 7 926 2 5 0 0 ; f a x : +I 61 7 926 4304,
Centrifuges reduce processing times
Amlcon's ProF/ux M 3 0 sanitary benchtop membrane filtration syst~?m.
M e m b r a n e T e c h n o l o g y No. 64
G e l m a n S c i e n c e s s a y s t h a t its Z - S p i n P l u s a n d N a n o S p i n Plus c e n t r i f u g a l devices r e d u c e p r o c e s s i n g t i m e s b y m a k i n g u s e of a u n i q u e s e a l i n g t e c h n o l o g y t h a t w i t h s t a n d s high c e n t r i f u g a l forces. These filters are 100 % tested for seal integrity to e n s u r e n o s a m p l e loss is b r o u g h t a b o u t b y b y p a s s or device failure. The i n s e r t d e s i g n allows i n v e r s i o n for n e a r l y c o m p l e t e recovery of samp][e r e t e n t a t e . r e g a r d l e s s of s a m p l e v o l u m e . A r a n g e of c e n t r i f u g a l devices are available for s a m p l e v o l u m e s of 0.5, 4 a n d 15 ml. Z - S p i n P l u s filters c o n t a i n 0.2 ~tm or 0.45 ~m Z - B i n d m e m b r a n e , a n optimized p o l y e t h e r s u l p h o n e m e m b r a n e t h a t is low p r o t e i n b i n d i n g . N a n o S p i n P l u s filters c o n t a i n
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News and Views
Gelman Sciences' Z-Spln Plus and NanoSpln Plus centrlfugal devices reduce processing times by making use of a unique sealing technology that withstands high centrlfugal forces. p o l y e t h e r s u l p h o n e m e m b r a n e s in 4K, 1OK, 3OK, 100K MWC. E a c h of t h e s e is c o m p a t i b l e w i t h c o m m o n l a b o r a t o r y c e n t r i f u g e s t h a t u s e e i t h e r fixed a n g l e or swinging bucket rotors. Forfurther information contact: Gelman Sciences, Brackmills Business Park, Caswell Road, Northampton, NN4 7EZ, UK. Tel: 01604 765141;fax: 01604 761383.
Hollow fibre UF cartridge range extended A / G T e c h n o l o g y C o r p o r a t i o n h a s f u r t h e r e x p a n d e d its line of c r o s s f l o w h o l l o w fibre u l t r a f i l t r a t i o n (UF) c a r t r i d g e s for c r i t i c a l biological s e p a r a t i o n s , w i t h t h e i n t r o d u c t i o n of t h e 3K a n d 30OK n o m i n a l m o l e c u l a r w e i g h t c u t o f f (NMWC) U F m e m b r a n e . The n e w 3K NMWC m e m b r a n e is s p e c i f i c a l l y d e s i g n e d for c o n c e n t r a t i o n a n d / o r d i a f l l t r a t i o n of p r o t e i n s , p e p U d e s a n d o t h e r low m o l e c u l a r w e i g h t s species. The 30OK NMWC m e m b r a n e c a n b e u s e d for v i r u s c o n c e n t r a t i o n or s e p a r a t i o n of v i r u s e s from low molecular weight proteins. T h e s e m e m b r a n e s a r e a v a i l a b l e in l a b o r a t o r y , pilot a n d full p r o d u c t i o n s c a l e c a r t r i d g e s w i t h m e m b r a n e a r e a s r a n g i n g f r o m a r o u n d 0.1 ft ~ to 140 ft . W i t h t h e s e a d d i t i o n s , A / G T e c h n o l o g y n o w offers a r a n g e of U F m e m b r a n e s w i t h a NMWC s p a n n i n g 3K to 50OK. T h e c o m p a n y a l s o offers a s e r i e s of hollow fibre m i c r o f i l t r a t i o n m e m b r a n e s in p o r e sizes from 0.1 to 0.65 p m for u s e in a v a r i e t y of cell c l a r i f i c a t i o n a n d concentration applications. Forfurther information contact: A / G Technology Corporation, 101 Hampton Avenue, Needham, MA 02194, USA. Tel: +1 61 7 449 5774; fax: +1 617 449 5786.
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A / G Technology Corporatlon's 3K and 300K nominal molecular weight cutoff (NMWC) UF hollow flbre membrane cartridges.
Whatman l a u n c h e s UF c e n t r i f u g e filters W h a t m a n I n t e r n a t i o n a l h a s e x p a n d e d its V e c t a S p i n 3 c e n t r i f u g e filter f a m i l y b y a d d i n g u l t r a f l l t r a t i o n v e r s i o n s to t h e r a n g e . By u s i n g t h e s e devices, r e s e a r c h e r s will b e a b l e to prepare small samples by ultraffltration conveniently a n d effectively u s i n g a s t a n d a r d l a b o r a t o r y centrifuge. T h e s e filters will find a p p l i c a t i o n in r e s e a r c h w o r k covering biochemistry, blotechnology, clinical and pharmaceutical development. E a c h V e c t a S p i n 3 c o n s i s t s of a 10 m l c a p a c i t y p o l y p r o p y l e n e t u b e w i t h a r e s e a l a b l e t e t h e r e d cap, c o n t a i n i n g a r e m o v a b l e filtering i n s e r t . In t h e n e w v e r s i o n , t h e i n s e r t i n c o r p o r a t e s a c h o i c e of p o l y s u l p h o n e or c e l l u l o s e t r i a c e t a t e u l t r a f i l t r a t i o n m e m b r a n e , a n d it is i n t o t h i s i n s e r t t h a t from 4 0 0 ~l to 3 m l of s a m p l e is p l a c e d . The e n t i r e a s s e m b l y is s p u n i n a s t a n d a r d l a b o r a t o r y centrifuge. R e t e n t a t e in t h e filter i n s e r t , or filtrate in t h e o u t e r c e n t r i f u g e t u b e , is e a s i l y r e c o v e r e d for f u r t h e r a n a l y s i s or u s e . U l t r a f l l t r a t i o n V e c t a S p i n 3 is a v a i l a b l e in f o u r s t a n d a r d v e r s i o n s : w i t h i n s e r t filtering m e m b r a n e of p o l y s u l p h o n e , in a c h o i c e of 1OK, 30K a n d lOOK m o l e c u l a r w e i g h t c u t - o f f (MWC), a n d c e l l u l o s e t r i a c e t a t e w i t h 20K MWC. C e l l u l o s e t r i a c e t a t e is p a r t i c u l a r l y r e c o m m e n d e d for n u c l e i c a c i d a p p l i c a t i o n s , a n d c a n b e o r d e r e d in a s m a l l e r c a p a c i t y v e r s i o n w i t h 12K MWC. Forfurther information contact: W h a t m a n International Ltd, Whatman House, St Leonard's Road, 2 0 / 2 0 Maidstone, Kent ME16 OLS, UK. Tel: 01622 676670;fax: 01622 677011.
M e m b r a n e T e c h n o l o g y No. 64
Benchtop system offered AInicon h a s i n t r o d u c e d the P r o F l u x M30 s a n i t a r y b e n c h t o p m e m b r a n e filtration s y s t e m d e s i g n e d for r a p i d concentration, p u r i f i c a t i o n or d e s a l t i n g of biological s o l u t i o n s . Specific a p p l i c a t i o n s i n c l u d e r e s e a r c h a n d d e v e l o p m e n t , s c a l e - u p or the p r o d u c t i o n of b i o p h a r m a c e u t i c a l s . P r o F l u x M30 offers the u s e r a choice of t a n g e n t i a l u l t r a f i l t r a t l o n or m i c r o f i l t r a t i o n with spiral, hollow fibre or a n y c a s s e t t e type filtration cartridges. The c o m p a c t s y s t e m f e a t u r e s a CIP reservoir u n i t a n d a n e x p a n d a b l e c a r t r i d g e manifold. D a t a a c q u i s i t i o n ls offered for r e p o r t i n g a n d historical t r e n d i n g o n a PC. For f u r t h e r information contact: Amlcon Inc, 72 Cherry Hill l)rlw:, Beverley, MA 01915, USA. Tel: +1 508 777 3 6 2 2 , f a x : +1 508 777 6204.
Ionics secures c o n t r a c t s in t h e Far E a s t Ionlcs Inc h a s a n n o u n c e d t h a t it h a s s e c u r e d c o n t r a c t s totalling 8 2 . 6 m i l l i o n to s u p p l y w a t e r t r e a t m e n t e q u i p m e n t for i n d u s t r i a l p r o j e c t s i n the Far East. The first r e q u i r e s e q u i p m e n t to t r e a t boiler feed w a t e r for a T a i w a n - b a s e d oii refinery. The s e c o n d covers the t r e a t m e n t of p r o c e s s w a t e r at S o u t h Korea's t h i r d largest a u t o m o b i l e m a n u f a c t u r e r , Kia Motors. Both s y s t e m s will u s e I o n i c s ' p r o p r i e t a r y electrodlalysis r e v e r s a l (EDR) technology. F u r t h e r n e w s r e v e a l s t h a t Ionlcs h a s r e p o r t e d record r e v e n u e s , for the q u a r t e r a n d s l x - m o n t h period e n d e d 30 J u n e . For the q u a r t e r , r e v e n u e s of 8 5 6 . 5 m i l l i o n were u p 13.5 % c o m p a r e d with the s a m e period i n 1994, while n e t i n c o m e of $ 4 . 6 m i l l i o n a n d e a r n i n g s per s h a r e of $ 0 . 3 2 were u p 28.9 % a n d 28.0 % respectively. For the first half, r e v e n u e s of $ 1 1 3 . 4 m i l l i o n were u p 10.3 % c o m p a r e d w i t h the first h a l f of 1994, while n e t i n c o m e of $8.7 m i l l i o n a n d e a r n i n g s per s h a r e of S0.61 were u p 25.3 % a n d 24.5 % respectively. The c o m p a n y believes t h a t the m a l o r factors c o n t r i b u t i n g to its r e c o r d r e s u l t s were i m p r o v e d p e r f o r m a n c e i n the c a p i t a l e q u i p m e n t b u s i n e s s a n d c o n t i n u e d s t r e n g t h i n the u l t r a p u r e w a t e r b u s i n e s s s e r v i n g the s e m i c o n d u c t o r indusi~ry. For f u r t h e r information contact: lonlcs Inc, PO Box 9131, Watertown, MA 02272-9131, USA. Tel: +I 61 7 926 2 5 0 0 ; f a x : +I 61 7 926 4304,
Centrifuges reduce processing times
Amlcon's ProF/ux M 3 0 sanitary benchtop membrane filtration syst~?m.
M e m b r a n e T e c h n o l o g y No. 64
G e l m a n S c i e n c e s s a y s t h a t its Z - S p i n P l u s a n d N a n o S p i n Plus c e n t r i f u g a l devices r e d u c e p r o c e s s i n g t i m e s b y m a k i n g u s e of a u n i q u e s e a l i n g t e c h n o l o g y t h a t w i t h s t a n d s high c e n t r i f u g a l forces. These filters are 100 % tested for seal integrity to e n s u r e n o s a m p l e loss is b r o u g h t a b o u t b y b y p a s s or device failure. The i n s e r t d e s i g n allows i n v e r s i o n for n e a r l y c o m p l e t e recovery of samp][e r e t e n t a t e . r e g a r d l e s s of s a m p l e v o l u m e . A r a n g e of c e n t r i f u g a l devices are available for s a m p l e v o l u m e s of 0.5, 4 a n d 15 ml. Z - S p i n P l u s filters c o n t a i n 0.2 ~tm or 0.45 ~m Z - B i n d m e m b r a n e , a n optimized p o l y e t h e r s u l p h o n e m e m b r a n e t h a t is low p r o t e i n b i n d i n g . N a n o S p i n P l u s filters c o n t a i n
3
News and Views
Gelman Sciences' Z-Spln Plus and NanoSpln Plus centrlfugal devices reduce processing times by making use of a unique sealing technology that withstands high centrlfugal forces. p o l y e t h e r s u l p h o n e m e m b r a n e s in 4K, 1OK, 3OK, 100K MWC. E a c h of t h e s e is c o m p a t i b l e w i t h c o m m o n l a b o r a t o r y c e n t r i f u g e s t h a t u s e e i t h e r fixed a n g l e or swinging bucket rotors. Forfurther information contact: Gelman Sciences, Brackmills Business Park, Caswell Road, Northampton, NN4 7EZ, UK. Tel: 01604 765141;fax: 01604 761383.
Hollow fibre UF cartridge range extended A / G T e c h n o l o g y C o r p o r a t i o n h a s f u r t h e r e x p a n d e d its line of c r o s s f l o w h o l l o w fibre u l t r a f i l t r a t i o n (UF) c a r t r i d g e s for c r i t i c a l biological s e p a r a t i o n s , w i t h t h e i n t r o d u c t i o n of t h e 3K a n d 30OK n o m i n a l m o l e c u l a r w e i g h t c u t o f f (NMWC) U F m e m b r a n e . The n e w 3K NMWC m e m b r a n e is s p e c i f i c a l l y d e s i g n e d for c o n c e n t r a t i o n a n d / o r d i a f l l t r a t i o n of p r o t e i n s , p e p U d e s a n d o t h e r low m o l e c u l a r w e i g h t s species. The 30OK NMWC m e m b r a n e c a n b e u s e d for v i r u s c o n c e n t r a t i o n or s e p a r a t i o n of v i r u s e s from low molecular weight proteins. T h e s e m e m b r a n e s a r e a v a i l a b l e in l a b o r a t o r y , pilot a n d full p r o d u c t i o n s c a l e c a r t r i d g e s w i t h m e m b r a n e a r e a s r a n g i n g f r o m a r o u n d 0.1 ft ~ to 140 ft . W i t h t h e s e a d d i t i o n s , A / G T e c h n o l o g y n o w offers a r a n g e of U F m e m b r a n e s w i t h a NMWC s p a n n i n g 3K to 50OK. T h e c o m p a n y a l s o offers a s e r i e s of hollow fibre m i c r o f i l t r a t i o n m e m b r a n e s in p o r e sizes from 0.1 to 0.65 p m for u s e in a v a r i e t y of cell c l a r i f i c a t i o n a n d concentration applications. Forfurther information contact: A / G Technology Corporation, 101 Hampton Avenue, Needham, MA 02194, USA. Tel: +1 61 7 449 5774; fax: +1 617 449 5786.
4
A / G Technology Corporatlon's 3K and 300K nominal molecular weight cutoff (NMWC) UF hollow flbre membrane cartridges.
Whatman l a u n c h e s UF c e n t r i f u g e filters W h a t m a n I n t e r n a t i o n a l h a s e x p a n d e d its V e c t a S p i n 3 c e n t r i f u g e filter f a m i l y b y a d d i n g u l t r a f l l t r a t i o n v e r s i o n s to t h e r a n g e . By u s i n g t h e s e devices, r e s e a r c h e r s will b e a b l e to prepare small samples by ultraffltration conveniently a n d effectively u s i n g a s t a n d a r d l a b o r a t o r y centrifuge. T h e s e filters will find a p p l i c a t i o n in r e s e a r c h w o r k covering biochemistry, blotechnology, clinical and pharmaceutical development. E a c h V e c t a S p i n 3 c o n s i s t s of a 10 m l c a p a c i t y p o l y p r o p y l e n e t u b e w i t h a r e s e a l a b l e t e t h e r e d cap, c o n t a i n i n g a r e m o v a b l e filtering i n s e r t . In t h e n e w v e r s i o n , t h e i n s e r t i n c o r p o r a t e s a c h o i c e of p o l y s u l p h o n e or c e l l u l o s e t r i a c e t a t e u l t r a f i l t r a t i o n m e m b r a n e , a n d it is i n t o t h i s i n s e r t t h a t from 4 0 0 ~l to 3 m l of s a m p l e is p l a c e d . The e n t i r e a s s e m b l y is s p u n i n a s t a n d a r d l a b o r a t o r y centrifuge. R e t e n t a t e in t h e filter i n s e r t , or filtrate in t h e o u t e r c e n t r i f u g e t u b e , is e a s i l y r e c o v e r e d for f u r t h e r a n a l y s i s or u s e . U l t r a f l l t r a t i o n V e c t a S p i n 3 is a v a i l a b l e in f o u r s t a n d a r d v e r s i o n s : w i t h i n s e r t filtering m e m b r a n e of p o l y s u l p h o n e , in a c h o i c e of 1OK, 30K a n d lOOK m o l e c u l a r w e i g h t c u t - o f f (MWC), a n d c e l l u l o s e t r i a c e t a t e w i t h 20K MWC. C e l l u l o s e t r i a c e t a t e is p a r t i c u l a r l y r e c o m m e n d e d for n u c l e i c a c i d a p p l i c a t i o n s , a n d c a n b e o r d e r e d in a s m a l l e r c a p a c i t y v e r s i o n w i t h 12K MWC. Forfurther information contact: W h a t m a n International Ltd, Whatman House, St Leonard's Road, 2 0 / 2 0 Maidstone, Kent ME16 OLS, UK. Tel: 01622 676670;fax: 01622 677011.
M e m b r a n e T e c h n o l o g y No. 64