INS;2009

INS;2009

Abstracts / Journal of the Neurological Sciences 333 (2013) e152–e214 e199 Abstract — WCN 2013 No: 983 Topic: 3 — Stroke Cerebrovascular risk factor...

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Abstracts / Journal of the Neurological Sciences 333 (2013) e152–e214

e199

Abstract — WCN 2013 No: 983 Topic: 3 — Stroke Cerebrovascular risk factors and depression: Report from National Ambulatory Medical Care Survey 2002–2009

Objective: The objective of this study was to describe the epidemiological and prognosis of stroke in the elderly at the Fann Teaching Hospital, in Dakar. Patients and methods: This is a retrospective study from 1st January 2001 to 1st November 2003 on patients aged 55 and older with stroke and had a brain CT scan. Sociodemographic data, medical history and surgical signs of severity associated with neurological symptoms and the prognosis were collected. Results: Records of 314 patients with stroke collected, 228 were aged 55 and over for a prevalence of 72.6%. The patient population consisted of 54.8% of women with a mean age of 67.9 years (± 8.5). Risk factors were dominated by high blood pressure (74.1%), diabetes (11.8%), the previous stroke (10.1%) and heart disease (3.1%). Ischemic stroke accounted for 65.8%. Coma (22.4%) and high blood pressure (21.9%) were associated with neurological symptoms. Lethality of 26.3% was observed with the main predictor coma (OR = 33.3, confidence interval 95% of 13 to 83.3). Conclusion: It should develop and implement a health education program to reduce morbidity and mortality from stroke in the elderly.

H. Egila, B. Rahim, M.A.K. Suri, M.F.K. Suri, A.I. Qureshi. Neurology, Zeenat Qureshi Stroke Research Center, Minnesota University, Minneapolis, MN, USA

doi:10.1016/j.jns.2013.07.798

mechanical thrombectomy in 11/19 countries. 6301 procedures were performed (mostly in Germany — 4428 and none in Iceland and Cyprus). An estimate of 0.19% of stroke patients were treated and (highest in Slovenia — 0.92%) .91% of the procedures were done by neuroradiologists and only 0.8% by neurologists. Conclusions: There is a lot of diversity in the use of endovascular procedures for acute stroke within Europe. The method is underused, but lack of evidence does not support the notion for widespread use. Neurologists' involvement is insufficient, but current UEMS guidelines support the training of neurologists in interventional neuroradiology. doi:10.1016/j.jns.2013.07.796

Background: Depression is a common psychiatric disorder that can occur as a result of many factors. Recently, a link between cerebrovascular risk factors and depression has been suggested. We performed this study to identify the association between depression and cerebrovascular risk factors. Method: We analyzed nationally representative data derived from patients enrolled in the National Ambulatory Medical Care Survey (NAMCS) between 2000 and 2009. Data analyzed included patients' age, gender, race/ethnicity, presence and control of cerebrovascular risk factors and self-reported depression. Results: During the 9-year study period, an estimated 148,857 patients enrolled in this study. There were 14,849 (7.4%) of 148,857 patients who reported depression. Of the patients with depression, 2.8% had a history of cerebrovascular diseases. Among patients with depression (compared with those without), frequency of body-mass index N30 (41.1% versus 31.9%, P b 0.05), cigarette smoking (33.8% versus 25.2%, P b 0.05), hypertension (28.4% versus 23.6%, P b 0.05), diabetes mellitus (12.3% versus 10.1%, P b 0.05), and hyperlipidemia (18.1% versus 13%, P b 0.05), was significantly higher. Conclusion: High frequencies of cerebrovascular risk factors were identified among persons with depression despite absence of any overt cerebrovascular disease. Further studies need to identify whether cerebrovascular risk factors have a causative role in depression or are a consequence of depression. doi:10.1016/j.jns.2013.07.797

Abstract — WCN 2013 No: 1432 Topic: 3 — Stroke Epidemiological and prognosis aspects of stroke of the elderly in the neurological clinic of Fann Teaching Hospital, Dakar — Senegal P.C. Mbonda Chimi, K. Toure, A. Sow, L.B. Seck, N.S. Diagne, M. Ndiaye, A.G. Diop, M.M. Ndiaye. Neurology, Fann Teaching Hospital, Dakar, Senegal Background: Strokes are a vital emergency and functional. Their frequency increases with the aging population so that the senior pays a heavy price for this condition.

Abstract — WCN 2013 No: 1443 Topic: 3 — Stroke Neuroplasticity in neurodegenerative diseases and stroke V. Demarin. Medical Center Aviva, Zagreb, Croatia Neurodegenerative diseases and stroke are foremost causes of medical, as well as socioeconomic problems in modern society leading to quality of life impairment of patients and caregivers. Disorders like stroke, dementia, Alzheimer's and Parkinson's disease, Huntington disease, multiple sclerosis and acquired brain trauma contribute to the decline of cognitive, motor, and sensory abilities. Neuroplasticity, also known as cortical remapping, challenges the idea that brain functions are fixed in certain time. It refers to changes in neural pathways and synapses which are due to continuous stimulation and practice enhanced by previous experience. Mirror-neurons system is activated both in action and observation. Practicing mental stimulation improves memory and attention. Neuroplasticity can act through two possible mechanisms on motor deficit and cognitive impairment, by forming new, or improving existing pathways. The changes in the cortex organization include an increase in the number and density of dendrites, synapses and neurotrophic factors. After damage has been afflicted to the motor cortex, changes of activation in other motor areas are observed. These changes occur in homologue areas of the non-affected hemisphere which can substitute for the lost functions or in the intact cortex adjacent to the damage. Thanks to these cortical reorganizations the patients can recover, at least in part, their lost abilities. Brain health is maintained through control of conventional vascular risk factors, practice of physical activity, healthy nutrition, stress management and mental stimulation. Challenging the brain with different tasks creates new neural connections and intensive exercise leads to improvement in neuroplasticity.

doi:10.1016/j.jns.2013.07.799