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Chemical libraries
Product News
Software for chemists
Chemical libraries for structure drawing. molecular modelling and chemical information management. Both packages arc available for \Vindo\vs and iLlacintosh. The new ITltra versions of (:hcmOfticc 4.0 and (:hemI)raw 4.0 include additional added-value programs to enhance prc)ductivit)- in the chemistr) l&orator). ‘I’he new ChemDraw -1.0 shows advances in database qucr) capability, chemical intelligence and publishing flexibility. <%cmI)raw can
Adept Scientific have released ChemOfflce 4.0 and ChemDraw 4.0 from CambridgeSoft Corporation. (:hcm~)rdw is the industry standard for chemical srructure drawing, while rhe (ZheniOff~ice suite features q~plications
be used to communicate structures and mechanisms in print or on the \I eb, faster than before. Important information such 3s molecular \vcight,
Oxford Asymmetry. through its division Oxford I)i\usit~, is klunchinfi 3 range of diverse. ~\cll-ch~iractcrizcc. single compound lead generation libmrics called ProspectorTM. ‘I’hcsc libraries are designed priniaril) for use in the identification of neu lead scrucuIres. I’xaniples include L(r)I ether, a-amino acid and p-:umino acid libraries; future libraries include the following chemical classes: tcrtiaq aniidcs,
Iyiincs.
‘I’he on
Prospecfor
both
PerSeptive Biosystems, Inc. has introduced the first robotic intcrfacc device designed spccificall~ to prepare biological samples for analysis by mass spectromctr). The SymBiotTM Sample Workstation fully automates and accelerates the current, manual sample treatment steps involved with time-offlight (‘1’01;) mass spectromctry. This
and
biaryls,
prosc~l~landin\.
“‘\’ libraries
coniniercially
arc
a\2ilal,lc
hsccl and
empirical formulae and clemental composition can easily bc calculated.
novel building blocks. Thcv provide substantial structural di\crsity, \\hilc ensuring that the library ~01iip0~11i& arc ‘drug-like’ in heir characteristics.
Gcle
Circle
letter a on reader response
card
letter d on reader response
Swing-out Automated Analysis of Biomolecules
py-rolidincs.
bcn~ordzcpinoncs
card.
nosepiece
Data analysis software SPSS Inc. has just released the new version 4.0 of SigmaPlot for Windows, the data analysis and prcscntation software. The software is used by scientists and engineers to analyze raw data, visualize results and create graphs. One new feature is the regression wiurd for cas): curve fitting and graphing which provides a
The new BXSOWI microscope
has
new platform is of potential use to scientisu involved with protein and peptide analysis, with DNA sequence and variation analysis, or with combinatorial chemistry for drug discovery. SymBiot creates an interface between two distinct entities: 3 sample containing complex biological substances, and a mass spectrometer that measures the mass to charge ratio of ions. Through this linkage, information about the sequence, variation or identity of substances contained in a sample can be derived automatically at a I’dtc exceeding 1000 per da);.
graphically illustrated equation, determines the initial pardmctcrs automatically and creates result graphs from them. SigmaPlot 1.0 also now includes time-series graphs, ternary plots. bubble plots and transparent 3D meshes. In addition, the user can select default graph settings co crcauz the precise graphs they want, by determining font type, symbol type and colour, background colour etc. SigmaPlot users can export their graphs ;1s EPS, 7’11~1~.WhiF and JPEG file formats. A SigmaPlot notebook allows users to document protocols, comment on data analysis techniques and formulate conclusions.
been designed by Olympus to incorporate a nosepiece with dual swing in/our action. This allows users
Circle
Grcle
Circle
letter b on reader response
card.
letter c on reader response
card.
to change magnification without altering the micro-manipulator settings. Changing between IO\Vset-up magnification and high observation magnification is achieved by sivinging the objective carrier in a longitudinal direction. Since there is no rotation of the nosepiece, objecti\.es can be changed \s:ithout adjustment of the manipulators, electrodes and head stages. ‘I’he 101~position of the stage ensures that a Z-stroke of 25mni is available for exchanging samples, Petri dishes and electrodes. letter e on reader response
card.
Software for chemists
Chemical libraries for structure drawing. molecular modelling and chemical information management. Both packages arc available for \Vindo\vs and iLlacintosh. The new ITltra versions of (:hcmOfticc 4.0 and (:hemI)raw 4.0 include additional added-value programs to enhance prc)ductivit)- in the chemistr) l&orator). ‘I’he new ChemDraw -1.0 shows advances in database qucr) capability, chemical intelligence and publishing flexibility. <%cmI)raw can
Adept Scientific have released ChemOfflce 4.0 and ChemDraw 4.0 from CambridgeSoft Corporation. (:hcm~)rdw is the industry standard for chemical srructure drawing, while rhe (ZheniOff~ice suite features q~plications
be used to communicate structures and mechanisms in print or on the \I eb, faster than before. Important information such 3s molecular \vcight,
Oxford Asymmetry. through its division Oxford I)i\usit~, is klunchinfi 3 range of diverse. ~\cll-ch~iractcrizcc. single compound lead generation libmrics called ProspectorTM. ‘I’hcsc libraries are designed priniaril) for use in the identification of neu lead scrucuIres. I’xaniples include L(r)I ether, a-amino acid and p-:umino acid libraries; future libraries include the following chemical classes: tcrtiaq aniidcs,
Iyiincs.
‘I’he on
Prospecfor
both
PerSeptive Biosystems, Inc. has introduced the first robotic intcrfacc device designed spccificall~ to prepare biological samples for analysis by mass spectromctr). The SymBiotTM Sample Workstation fully automates and accelerates the current, manual sample treatment steps involved with time-offlight (‘1’01;) mass spectromctry. This
and
biaryls,
prosc~l~landin\.
“‘\’ libraries
coniniercially
arc
a\2ilal,lc
hsccl and
empirical formulae and clemental composition can easily bc calculated.
novel building blocks. Thcv provide substantial structural di\crsity, \\hilc ensuring that the library ~01iip0~11i& arc ‘drug-like’ in heir characteristics.
Gcle
Circle
letter a on reader response
card
letter d on reader response
Swing-out Automated Analysis of Biomolecules
py-rolidincs.
bcn~ordzcpinoncs
card.
nosepiece
Data analysis software SPSS Inc. has just released the new version 4.0 of SigmaPlot for Windows, the data analysis and prcscntation software. The software is used by scientists and engineers to analyze raw data, visualize results and create graphs. One new feature is the regression wiurd for cas): curve fitting and graphing which provides a
The new BXSOWI microscope
has
new platform is of potential use to scientisu involved with protein and peptide analysis, with DNA sequence and variation analysis, or with combinatorial chemistry for drug discovery. SymBiot creates an interface between two distinct entities: 3 sample containing complex biological substances, and a mass spectrometer that measures the mass to charge ratio of ions. Through this linkage, information about the sequence, variation or identity of substances contained in a sample can be derived automatically at a I’dtc exceeding 1000 per da);.
graphically illustrated equation, determines the initial pardmctcrs automatically and creates result graphs from them. SigmaPlot 1.0 also now includes time-series graphs, ternary plots. bubble plots and transparent 3D meshes. In addition, the user can select default graph settings co crcauz the precise graphs they want, by determining font type, symbol type and colour, background colour etc. SigmaPlot users can export their graphs ;1s EPS, 7’11~1~.WhiF and JPEG file formats. A SigmaPlot notebook allows users to document protocols, comment on data analysis techniques and formulate conclusions.
been designed by Olympus to incorporate a nosepiece with dual swing in/our action. This allows users
Circle
Grcle
Circle
letter b on reader response
card.
letter c on reader response
card.
to change magnification without altering the micro-manipulator settings. Changing between IO\Vset-up magnification and high observation magnification is achieved by sivinging the objective carrier in a longitudinal direction. Since there is no rotation of the nosepiece, objecti\.es can be changed \s:ithout adjustment of the manipulators, electrodes and head stages. ‘I’he 101~position of the stage ensures that a Z-stroke of 25mni is available for exchanging samples, Petri dishes and electrodes. letter e on reader response
card.