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Chemical Modeling of Aqueous Systems II
BOOK
iv Ekctropbresis:
MAUREENMELVIN, Chichester,
REVIEWS
1987. Pages xxi + 131. f9.95 (flexicover); f28.00 (cloth).
This a good introduction to the technique of electrophoresis. It describes the various versions of electrophoresis, the types of support media used, the factors affecting mobility, and the types of detectors available. There is a small section on immunoelectrophoresis and another on two-dimensional techniques. The book is written in simple, though at times oversimplified, terms, and is well illustrated, except for Fig. 2.3a which contains several mistakes. Some of the self-assessment questions are rather difficult, but the author’s responses are an excellent guide on how they can and should be answered. A cautionary note should have been included warning students that some of the stains used in detection are hazardous to health, for example, ethidinium bromide is a mutagen, ninhydrin and ANS are irritants, and dansyl chloride is corrosive. J. B. CKAIG
Chemical Mod&g ofA~IWOUS Systems II: D. C. MELCHIOR~~~ R. L. BASSEIT(editors), ACS, Washington, DC, 1990. Pages xvi + 556. $89.95 (U.S.), $107.95 (elsewhere). This book is based on a symposium held in 1988, which sets the limits for references. It consists of 41 chapters by separate authors, the work being almost entirely American in origin. The aqueous systems involved are predominantly natural surface and ground waters, although hydrothermal conditions are covered to some extent. Industrial water systems are not specifically considered. The early chapters are of the greatest generality, discussing activity coefficients in concentrated solutions, the effects of pressure and the solubility of volatile electrolytes. Other sections concentrate on solid/solution equilibria, transport, adsorption effects and the role of organ& Although many of these later chapters refer to specific instances, they are often also exemplary. This book can be recommended to the research worker and graduate student in limnology, oceanography and, to a lesser extent, geochemistry as a very useful, up-to-date and authoritative source of data and ideas, many of which should also be relevant to those concerned with the fate of industrial chemical discharges. D.
MIDGLEY
SteroidAnaIysis in the PharmaceuticalIndustry: S. G&i~cjG(editor), Ellis Horwood, Chichester, 1989. Pages xi + 398. f69.50. The 25 authors that have contributed to this impressive text are based in various countries, notably Hungary and the U.S.A., and they represent much of the steroid industry. The editorial staff must be congratulated for bringing these authors together and for producing such a comprehensive work. A short introduction on industrial steroid analysis is followed by an excellent chapter on methods used in steroid analysis. It is certainly worth buying the book just for this chapter, which covers spectroscopic methods, chromatographic analysis, protein binding and electroanalytical methods. The 10 authors who have contributed to the chapter have cited over 800 references and all relevant analytical methods are covered at an introductory level. The smaller chapter on structure elucidation covers previously mentioned instrumentation, e.g., IR, NMR and GCMS, and the powerful X-ray crystallographic technique is also briefly mentioned. The remaining chapters deal with analytical control of the production of steroids, analytical control of steroid formulations and determination of steroids in biological media. Analytical aspects of preformulation studies are included and there is a section on health control of workers in steroid hormone production. Many case histories of real analytical problems are given and the practical nature of the book is very evident. Also, as might be expected in a text compiled by different authors, there is some overlap between chapters. Chromatography, especially HPLC, is of prime importance in steroid analysis and this topic is well covered, not only in the section on chromatographic analysis, but also throughout the book. Thin-layer chromatography is not neglected and although a large number of GLC stationary phases (e.g., silicone oils) have been used in packed columns, the more recent fused-silica capillaries with chemically-bonded phases are now recommended by the authors for routine assay work. Resolving chiral steroids by the use of cyclodextrin and the interfacing of LC with MS is also mentioned. The book, which contains well over 1200 references, is illustrated with many well-produced spectra and chromatograms. There is much here that will be of great interest to all chemists and pharmacists who work with steroids. P. J. Cox
Packings and Stationary PIwee in Chromatognpbic Techniques: K. K. viii + 835. $150 (U.S. and Canada), $180 (elsewhere).
UNGER (editor),
Dekker, New York, 1990. Pages
Stationary phases have been the subject of relatively few books in chromatography yet they are the most important part of any separation. This deficiency has been rectified in this compilation edited by Klaus Unger which has brought together materials used in the different areas of chromatography. The book has three main areas. Introductory chapters cover the history of packing materials and a survey of the different types of stationary phases. The second section is the most important, with broad surveys of stationary phases for the main chromatographic methods. Materials for gas-liquid chromatography are considered by Piirschmann and Engewald. They include gassolid materials and comparisons of the different liquid phases. Thin-layer chromatography sorbents, including reversed phase, cellulose
iv Ekctropbresis:
MAUREENMELVIN, Chichester,
REVIEWS
1987. Pages xxi + 131. f9.95 (flexicover); f28.00 (cloth).
This a good introduction to the technique of electrophoresis. It describes the various versions of electrophoresis, the types of support media used, the factors affecting mobility, and the types of detectors available. There is a small section on immunoelectrophoresis and another on two-dimensional techniques. The book is written in simple, though at times oversimplified, terms, and is well illustrated, except for Fig. 2.3a which contains several mistakes. Some of the self-assessment questions are rather difficult, but the author’s responses are an excellent guide on how they can and should be answered. A cautionary note should have been included warning students that some of the stains used in detection are hazardous to health, for example, ethidinium bromide is a mutagen, ninhydrin and ANS are irritants, and dansyl chloride is corrosive. J. B. CKAIG
Chemical Mod&g ofA~IWOUS Systems II: D. C. MELCHIOR~~~ R. L. BASSEIT(editors), ACS, Washington, DC, 1990. Pages xvi + 556. $89.95 (U.S.), $107.95 (elsewhere). This book is based on a symposium held in 1988, which sets the limits for references. It consists of 41 chapters by separate authors, the work being almost entirely American in origin. The aqueous systems involved are predominantly natural surface and ground waters, although hydrothermal conditions are covered to some extent. Industrial water systems are not specifically considered. The early chapters are of the greatest generality, discussing activity coefficients in concentrated solutions, the effects of pressure and the solubility of volatile electrolytes. Other sections concentrate on solid/solution equilibria, transport, adsorption effects and the role of organ& Although many of these later chapters refer to specific instances, they are often also exemplary. This book can be recommended to the research worker and graduate student in limnology, oceanography and, to a lesser extent, geochemistry as a very useful, up-to-date and authoritative source of data and ideas, many of which should also be relevant to those concerned with the fate of industrial chemical discharges. D.
MIDGLEY
SteroidAnaIysis in the PharmaceuticalIndustry: S. G&i~cjG(editor), Ellis Horwood, Chichester, 1989. Pages xi + 398. f69.50. The 25 authors that have contributed to this impressive text are based in various countries, notably Hungary and the U.S.A., and they represent much of the steroid industry. The editorial staff must be congratulated for bringing these authors together and for producing such a comprehensive work. A short introduction on industrial steroid analysis is followed by an excellent chapter on methods used in steroid analysis. It is certainly worth buying the book just for this chapter, which covers spectroscopic methods, chromatographic analysis, protein binding and electroanalytical methods. The 10 authors who have contributed to the chapter have cited over 800 references and all relevant analytical methods are covered at an introductory level. The smaller chapter on structure elucidation covers previously mentioned instrumentation, e.g., IR, NMR and GCMS, and the powerful X-ray crystallographic technique is also briefly mentioned. The remaining chapters deal with analytical control of the production of steroids, analytical control of steroid formulations and determination of steroids in biological media. Analytical aspects of preformulation studies are included and there is a section on health control of workers in steroid hormone production. Many case histories of real analytical problems are given and the practical nature of the book is very evident. Also, as might be expected in a text compiled by different authors, there is some overlap between chapters. Chromatography, especially HPLC, is of prime importance in steroid analysis and this topic is well covered, not only in the section on chromatographic analysis, but also throughout the book. Thin-layer chromatography is not neglected and although a large number of GLC stationary phases (e.g., silicone oils) have been used in packed columns, the more recent fused-silica capillaries with chemically-bonded phases are now recommended by the authors for routine assay work. Resolving chiral steroids by the use of cyclodextrin and the interfacing of LC with MS is also mentioned. The book, which contains well over 1200 references, is illustrated with many well-produced spectra and chromatograms. There is much here that will be of great interest to all chemists and pharmacists who work with steroids. P. J. Cox
Packings and Stationary PIwee in Chromatognpbic Techniques: K. K. viii + 835. $150 (U.S. and Canada), $180 (elsewhere).
UNGER (editor),
Dekker, New York, 1990. Pages
Stationary phases have been the subject of relatively few books in chromatography yet they are the most important part of any separation. This deficiency has been rectified in this compilation edited by Klaus Unger which has brought together materials used in the different areas of chromatography. The book has three main areas. Introductory chapters cover the history of packing materials and a survey of the different types of stationary phases. The second section is the most important, with broad surveys of stationary phases for the main chromatographic methods. Materials for gas-liquid chromatography are considered by Piirschmann and Engewald. They include gassolid materials and comparisons of the different liquid phases. Thin-layer chromatography sorbents, including reversed phase, cellulose