Chemistry and biochemistry of the amino acids

Chemistry and biochemistry of the amino acids

250 Journal of Chromatography, 342 (1985) 250 Biomedical Applications Elsevier Science Publishers B.V., Amsterdam - Printed in The Netherlands CHROM...

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250

Journal of Chromatography, 342 (1985) 250 Biomedical Applications Elsevier Science Publishers B.V., Amsterdam - Printed in The Netherlands

CHROMBIO.

2591

Book Review Chemistry and biochemistry Chapman & Hall, London, ISBN o-412-23410-6.

of the amino acids, edited by G.C. Barrett, New York, 1984, x + 684 pp., price Z 49.50,

This typical multi-author book covers in twenty-two chapters practically all aspects of the chemistry and biochemistry of amino acids; it is pleasing to note that by the term amino acids the authors understand not only the “classical twenty”, but also those, which arise during the post-translational modifications. For workers in separation science there are some chapters that are probably of less importance from their point of view. On the other hand, other are well worth reading, namely, Resolution of amino acids (G.C. Barrett), Ion exchange separation of amino acids (P.E. Hare, P.A. St. John and M.H. Engel), Liquid chromatography of amino acids and their derivatives (D. Perrett), Gas-liquid chromatographic separation of amino acids and their derivatives (M.H. Engel and P.E. Hare), Mass spectrometry of amino acids and their derivatives (R.A.W. Johnstone and M.E. Rose) and Calorimetric and fluorometric detection of amino acids (G.C. Rosenthal). In addition to these chapters devoted to the separation procedures as such, there is a lot of additional interesting information scattered throughout the book that may be well exploited by the chromatographers. As with most multi-author volumes, this one suffers from non-uniformity between individual chapters, but this does not exceed an acceptable limit. The chapters on amino acid separations are very well written and especially useful. The literature is covered up to 1981-1982; the lack of more recent literature is a pity. The relationship between classical methods for amino acid separations and modern approaches is well proportioned. The book also offers a fair comparison of chromatographic and non-chromatographic separation procedures that is not easy to find elsewhere. As far as the completeness of separation procedures is concerned, the volume neglects electromigration processes completely. In summary, this is a reasonable book that can be recommended to all those involved in amino acid separations, in spite of the fact that the problems of separation comprise only a part of the whole volume. Prague (Czechoslovakia)

Z. DEYL