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Chromatographic reviews
JOURNAL OF ELECTROASALYTICAL CHEMISTRY
Book Chromatogra@ic
Re-~iews,
ing Company, Amsterdam, tions and 51 tables, s3_
491
Reviews
Volume 5, edited by MICHAEL LEDERER, Elsevier PublishLondon and New York, 1963, ix + z+ pages, 35 illustra-
The publication
of reviews in the JozsmaZ of Chronzatopaphy has ceased consequently, Rmiezm will in the future contain only new material, in contrast to Volume 5 which includes three reviews previously published in the Jo~vmZ of C~YOmatog7aphy in addition to an original monograph and two new reviews. The book starts with a contribution from WALDMANN-MEYER who discusses in detail, with z5g references, the protein mobilities and ion binding constants evaluated by zone electrophoresis. The main problems appear to have been solved and may well lead to further progress in studies of the electrochemical properties of proteins and other macromolecules. The next chapter m&es envious reading for any routine user of paper and thinlay-er chromatography; ARX ASD NEHER describe with good illustrations and diagrams the planning that went into the construction of an efficient chromatography laboratory for the Pharmaceutical Research Division of CIBA Ltd. The ever-interesting relationship between paper chromatographic behaviour and organic structures is discussed on the next IOO pages by GREEX, MARCIXKIEWICZ AND MCHALE. and interpreted in terms of the electronic theory. This monograph is presented in eight sections, the first describing a new method of tankless, or flat-bed, chromatography for the accurate determination of R fir values. Using this method alkyl dinitrobenzoates are shown to obey Martin’s equation with respect to d&r (CHa). The remaining sections discuss the application of their ideas to a large number of compounds, including phenols, alkoxyphenols, coumaranols, chromanols, tocopherols, vitamins K, ubiquinones, ubichromenols, thienol, p-nitrosophenols, and m- and $-derivatives of benzene. The results are interpretated by consideration of the effect on Rnr val-ues of steric and electronic factors, including effects of unsaturaintra-molecular hydrogen bonding, tautomerism and tion and chain branching, hyperconjugation. The separation of organic substances by counter-current distribution is surveyed by CA&OVI with 492 references. Then O_~KEY reviews the progress made in the application of paper chromatography to the oestrogens, a very important technique in clinical biochemistry and discusses the relationship between mobility and their chemical structures. Useful tables of 22~ values of oestrogens in different solvents are given and key references are cited_ The book concludes with a discussion of the application of gas chromatography to inorganic compounds. TADMOR discusses the problems and possible developments of this technique and reviews the separations achieved to date, The high standard of Elsevier presentation is evident; the layout is excellent, the diagrams clear and the paper of good quality. The book is a mine of information on chromatography and should find a place in every scientific library and laboratory. Chromatogvaphic
LESLIE HOUGH, Chemistry
Department, J_ Ebdroar.al.
University Chem..
of Bristol
7 (1964)
qgI-qg+
Book Chromatogra@ic
Re-~iews,
ing Company, Amsterdam, tions and 51 tables, s3_
491
Reviews
Volume 5, edited by MICHAEL LEDERER, Elsevier PublishLondon and New York, 1963, ix + z+ pages, 35 illustra-
The publication
of reviews in the JozsmaZ of Chronzatopaphy has ceased consequently, Rmiezm will in the future contain only new material, in contrast to Volume 5 which includes three reviews previously published in the Jo~vmZ of C~YOmatog7aphy in addition to an original monograph and two new reviews. The book starts with a contribution from WALDMANN-MEYER who discusses in detail, with z5g references, the protein mobilities and ion binding constants evaluated by zone electrophoresis. The main problems appear to have been solved and may well lead to further progress in studies of the electrochemical properties of proteins and other macromolecules. The next chapter m&es envious reading for any routine user of paper and thinlay-er chromatography; ARX ASD NEHER describe with good illustrations and diagrams the planning that went into the construction of an efficient chromatography laboratory for the Pharmaceutical Research Division of CIBA Ltd. The ever-interesting relationship between paper chromatographic behaviour and organic structures is discussed on the next IOO pages by GREEX, MARCIXKIEWICZ AND MCHALE. and interpreted in terms of the electronic theory. This monograph is presented in eight sections, the first describing a new method of tankless, or flat-bed, chromatography for the accurate determination of R fir values. Using this method alkyl dinitrobenzoates are shown to obey Martin’s equation with respect to d&r (CHa). The remaining sections discuss the application of their ideas to a large number of compounds, including phenols, alkoxyphenols, coumaranols, chromanols, tocopherols, vitamins K, ubiquinones, ubichromenols, thienol, p-nitrosophenols, and m- and $-derivatives of benzene. The results are interpretated by consideration of the effect on Rnr val-ues of steric and electronic factors, including effects of unsaturaintra-molecular hydrogen bonding, tautomerism and tion and chain branching, hyperconjugation. The separation of organic substances by counter-current distribution is surveyed by CA&OVI with 492 references. Then O_~KEY reviews the progress made in the application of paper chromatography to the oestrogens, a very important technique in clinical biochemistry and discusses the relationship between mobility and their chemical structures. Useful tables of 22~ values of oestrogens in different solvents are given and key references are cited_ The book concludes with a discussion of the application of gas chromatography to inorganic compounds. TADMOR discusses the problems and possible developments of this technique and reviews the separations achieved to date, The high standard of Elsevier presentation is evident; the layout is excellent, the diagrams clear and the paper of good quality. The book is a mine of information on chromatography and should find a place in every scientific library and laboratory. Chromatogvaphic
LESLIE HOUGH, Chemistry
Department, J_ Ebdroar.al.
University Chem..
of Bristol
7 (1964)
qgI-qg+