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Chromatographic separations of stereoisomers
Journal of Chromatogrtrphy, 437 (I 988) 458 Elsevier Science Publishers B.V., Amsterdam CHROM.
-
Printed
in The Netherlands
20 319
Book Review
Chromatographic separations of stereoisomers, by R. W. Souter, CRC Press, Boca
Raton, FL, 1985, VII + 241 pp, price, US$99.00 (U.S.A.), US$ 114.00 (rest of world), ISBN O-8493-6127-3. This compilation of stereoisomer separations is perhaps the most complete review to date of an important field now being frequently reviewed. Treating gas, liquid, thin-layer and paper chromatographic separations, Souter covers the bulk of the separations of enantiomers and diastereomers reported prior to early 1984. As with any review in a rapidly developing area, this review is already a bit dated, but is nevertheless an‘excellent place to start for an in-depth coverage of this topic. The first chapter is a brief review of stereochemical concepts, whereas Ch. 2 and 3 deal, respectively, with gas and liquid chromatographic separations of stereoisomers. Both chapters have the desirable features of listing derivatizing agents and procedures and sources for the chiral stationary phases then available. Ch. 3 also covers the use of chiral additives to the eluent. Ch. 4, the last, covers a variety of miscellaneous topics, all of general interest, and of some practical utility. For example, chiral adsorbents such as potato starch, triacetylcellulose, lactose, and crown ethers are mentioned; thin-layer, paper, and electrophoretic techniques are discussed, as are ligand-exchange methods. The text is richly documented and replete with many clear figures and tables. All in all, every worker concerned with the separation of stereoisomers will profit from convenient access to this book, the most comprehensive coverage of the field (up to early 1984) yet to appear. Urbana, IL (U.S.A
.)
WILLIAM
H. PIRKLE
-
Printed
in The Netherlands
20 319
Book Review
Chromatographic separations of stereoisomers, by R. W. Souter, CRC Press, Boca
Raton, FL, 1985, VII + 241 pp, price, US$99.00 (U.S.A.), US$ 114.00 (rest of world), ISBN O-8493-6127-3. This compilation of stereoisomer separations is perhaps the most complete review to date of an important field now being frequently reviewed. Treating gas, liquid, thin-layer and paper chromatographic separations, Souter covers the bulk of the separations of enantiomers and diastereomers reported prior to early 1984. As with any review in a rapidly developing area, this review is already a bit dated, but is nevertheless an‘excellent place to start for an in-depth coverage of this topic. The first chapter is a brief review of stereochemical concepts, whereas Ch. 2 and 3 deal, respectively, with gas and liquid chromatographic separations of stereoisomers. Both chapters have the desirable features of listing derivatizing agents and procedures and sources for the chiral stationary phases then available. Ch. 3 also covers the use of chiral additives to the eluent. Ch. 4, the last, covers a variety of miscellaneous topics, all of general interest, and of some practical utility. For example, chiral adsorbents such as potato starch, triacetylcellulose, lactose, and crown ethers are mentioned; thin-layer, paper, and electrophoretic techniques are discussed, as are ligand-exchange methods. The text is richly documented and replete with many clear figures and tables. All in all, every worker concerned with the separation of stereoisomers will profit from convenient access to this book, the most comprehensive coverage of the field (up to early 1984) yet to appear. Urbana, IL (U.S.A
.)
WILLIAM
H. PIRKLE