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CHRONIC GRAFT-VS-HOST DISEASE: A CASE REPORT
OOOO Volume 129, Number 1 CARCINOMA EXPLEOMORPHIC ADENOMA WITH FOCAL ABERRANT MAMMAGLOBIN EXPRESSION. VIVIAN PETERSEN WAGNER, CIRO DANTAS, ALBINA MESSIAS DE ALMEIDA MILANI ALTEMANI, JULIANA ROMANINI, ANTONIO CARLOS € KRUEL PUTTEN, PABLO AGUSTIN VARGAS and, MANOELA DOMINGUES MARTINS A 70-year-old male patient sought dental care for oral rehabilitation. A painless firm nodule covered by normal mucosa was detected during the examination in the retromolar region. The lesion was well circumscribed, and an excisional biopsy was performed. Histopathologic analysis revealed a partially encapsulated tumor composed by sheets and islands of ductal-type epithelial cells with moderate cytologic atypia. Pseudocystic ductal spaces and areas of a trabecular patterns with extensive stromal hyalinization were observed. Immunohistochemical results from CK7, CK14, S100, smooth muscle actin, calponin, p63, and Ki67 were consistent with carcinoma ex pleomorphic adenoma (CaExPA). Interestingly, the tumor demonstrated a focal yet strong positivity for mammaglobin. The ETV6-NRKT3 translocation, however, was absent. Therefore, a final diagnosis of CaExPA with focal aberrant mammaglobin expression was established. The patient was referred to a head and neck surgeon and submitted to a new surgical procedure. No recurrence was detected after 6 months.
SPINDLE CELL LIPOMA OF THE ORAL CAVITY: CASE REPORT OF AN UNCOMMON AND DISTINCT VARIANT OF LIPOMA. BRUNA FERNANDES DO CARMO CARVALHO, NAYARA DE SA RODRIGUES, JANETE DIAS ALMEIDA, PASQUAL BONZANINI NETO, ANA LIA ANBINDER, ^ LUIZ EDUARDO BLUMER ROSA and, MONICA GHISLAINE OLIVEIRA ALVES Spindle cell lipoma (SCL), an uncommon histologic variant of lipoma, is a benign tumor that often occurs in the posterior neck or shoulder with rare occurrence in the oral cavity. It comprises about 1.6% of intraoral lipomatous tumors. The aim of the case report is to present the histopathologic features of a SCL. A 60-year-old woman with noncontributory medical history was examined for an asymptomatic nodule in the left buccal mucosa. The intraoral examination showed a 7-mm sessile and well-circumscribed nodule with firm consistency and smooth surface covered by slightly whitish mucosa. Excisional biopsy was carried out based on a clinical diagnosis of inflammatory fibrous hyperplasia. The histopathology demonstrated mature adipose tissue, spindle cells (CD34+), and many mast cells in a connective tissue stroma. The diagnosis of SCL was hence established. The patient is being followed up.
CHRONIC GRAFT-VS-HOST DISEASE: A CASE REPORT. MATEUS JOSE DE CARVALHO PEREIRA, FELIPE PAIVA FONSECA, RICARDO ALVES DE MESQUITA, TARCILIA APARECIDA DA SILVA and, VAGNER RODRIGUES SANTOS This study presents a case report of a 42-year-old black woman who showed up in a clinic of pathology and stomatology because of oral manifestations of chronic graft-vs-host disease
ABSTRACTS
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(cGVHD) after allogeneic bone marrow transplant. The disease manifestations showed as multiple white plaques and striations on the lips, labial mucosa, ventral surface of the tongue, oropharynx, palate, and buccal mucosa as well as areas of atrophic mucosa, burning mouth, and xerostomia. Based on the clinical findings and the patient’s history, the diagnosis was cGVHD, and an incisional biopsy of the minor salivary glands of the inferior lip was performed to dismiss other pathologies. The patient was referred to medical assistance because of her systemic condition.
CARE AND DENTAL INTEGRALITY IN CARRIERS OF DOWN SYNDROME. VANESSA SANTOS RODRIGUES CANUTO, LUIZA MADALENA MENDES DA VERA CRUZ, LEONARDO DE SOUZA LOUZARDO, ANTONIA PATRICIA OLIVEIRA BARROS, CRISLYNE MENDES DA VERA CRUZ, JOYCE HELENA MONTEIRO BARBOSA and, ERICK NELO PEDREIRA Down syndrome is a chromosomal disorder caused by trisomy in chromosome 21.The oral cavity manifests many changes induced by the environment as well as alteration in immune system. The objective is to report a 12-year-old male pediatric dental patient who is attended in the dental care service for patients with special needs. He was a heart patient and a carrier of Down syndrome, presenting aggressiveness and endurance on the dental attendance. His problem was a toothache; however, the clinical examination verified mixed dentition, periodontal disease, high incidence of dental caries, malocclusion, staining on teeth, mouth breathing, narrow palate, and macroglossia. The treatment was accomplished through adequacy, prophylaxis, fluoride application, restorations, periapical radiography to exodontia, and the "hug technique." The importance of orientation about the dental health care of patients with Down syndrome to the professional teams is essential, beyond proper procedure and knowledge about the oral characteristics and how a dental surgeon could act to promote the integrality.
ORAL LESION SECONDARY TO ORAL SEX. LAIS DE BARROS PINTO GRIFONI and, CLAUDIA MARIA NAVARRO Fellatio is modality of oral sex in which the penis is placed into the mouth of another person contacting the soft palate, and, sometimes, oral lesions in the contact area can be observed. Usually these lesions appear in the context of sexual abuse, but they are also seen after consensual sex, frequently in young women or homosexual men. A 24-year-old woman came to our clinic complaining of asymptomatic red petechiae on the palate. There was cervical lymphadenopathy. Oral examination revealed small red spots on the soft palate, and patient confirmed the practice of fellatio. The differential diagnosis included syphilis and blood dyscrasias. The anamnesis was noncontributory. Seven days after cessation of fellatio the oral lesions resolved. The laboratory tests were within normal values. It is important that dentists know the oral manifestations of oral sex to include this clinical hypothesis in the diagnosis of palatal lesions.
ORAL AMYLOIDOSIS: 2 CASE REPORTS. PRISCILA ANA BRAGA DA SILVA ROCHA, RUTH TRAMONTANI RAMOS, GERALDO OLIVEIRA SILVA JUNIOR, MARILIA HEFFER CANTISAN ^ PIRES and, FABIO RAMOA
SPINDLE CELL LIPOMA OF THE ORAL CAVITY: CASE REPORT OF AN UNCOMMON AND DISTINCT VARIANT OF LIPOMA. BRUNA FERNANDES DO CARMO CARVALHO, NAYARA DE SA RODRIGUES, JANETE DIAS ALMEIDA, PASQUAL BONZANINI NETO, ANA LIA ANBINDER, ^ LUIZ EDUARDO BLUMER ROSA and, MONICA GHISLAINE OLIVEIRA ALVES Spindle cell lipoma (SCL), an uncommon histologic variant of lipoma, is a benign tumor that often occurs in the posterior neck or shoulder with rare occurrence in the oral cavity. It comprises about 1.6% of intraoral lipomatous tumors. The aim of the case report is to present the histopathologic features of a SCL. A 60-year-old woman with noncontributory medical history was examined for an asymptomatic nodule in the left buccal mucosa. The intraoral examination showed a 7-mm sessile and well-circumscribed nodule with firm consistency and smooth surface covered by slightly whitish mucosa. Excisional biopsy was carried out based on a clinical diagnosis of inflammatory fibrous hyperplasia. The histopathology demonstrated mature adipose tissue, spindle cells (CD34+), and many mast cells in a connective tissue stroma. The diagnosis of SCL was hence established. The patient is being followed up.
CHRONIC GRAFT-VS-HOST DISEASE: A CASE REPORT. MATEUS JOSE DE CARVALHO PEREIRA, FELIPE PAIVA FONSECA, RICARDO ALVES DE MESQUITA, TARCILIA APARECIDA DA SILVA and, VAGNER RODRIGUES SANTOS This study presents a case report of a 42-year-old black woman who showed up in a clinic of pathology and stomatology because of oral manifestations of chronic graft-vs-host disease
ABSTRACTS
e67
(cGVHD) after allogeneic bone marrow transplant. The disease manifestations showed as multiple white plaques and striations on the lips, labial mucosa, ventral surface of the tongue, oropharynx, palate, and buccal mucosa as well as areas of atrophic mucosa, burning mouth, and xerostomia. Based on the clinical findings and the patient’s history, the diagnosis was cGVHD, and an incisional biopsy of the minor salivary glands of the inferior lip was performed to dismiss other pathologies. The patient was referred to medical assistance because of her systemic condition.
CARE AND DENTAL INTEGRALITY IN CARRIERS OF DOWN SYNDROME. VANESSA SANTOS RODRIGUES CANUTO, LUIZA MADALENA MENDES DA VERA CRUZ, LEONARDO DE SOUZA LOUZARDO, ANTONIA PATRICIA OLIVEIRA BARROS, CRISLYNE MENDES DA VERA CRUZ, JOYCE HELENA MONTEIRO BARBOSA and, ERICK NELO PEDREIRA Down syndrome is a chromosomal disorder caused by trisomy in chromosome 21.The oral cavity manifests many changes induced by the environment as well as alteration in immune system. The objective is to report a 12-year-old male pediatric dental patient who is attended in the dental care service for patients with special needs. He was a heart patient and a carrier of Down syndrome, presenting aggressiveness and endurance on the dental attendance. His problem was a toothache; however, the clinical examination verified mixed dentition, periodontal disease, high incidence of dental caries, malocclusion, staining on teeth, mouth breathing, narrow palate, and macroglossia. The treatment was accomplished through adequacy, prophylaxis, fluoride application, restorations, periapical radiography to exodontia, and the "hug technique." The importance of orientation about the dental health care of patients with Down syndrome to the professional teams is essential, beyond proper procedure and knowledge about the oral characteristics and how a dental surgeon could act to promote the integrality.
ORAL LESION SECONDARY TO ORAL SEX. LAIS DE BARROS PINTO GRIFONI and, CLAUDIA MARIA NAVARRO Fellatio is modality of oral sex in which the penis is placed into the mouth of another person contacting the soft palate, and, sometimes, oral lesions in the contact area can be observed. Usually these lesions appear in the context of sexual abuse, but they are also seen after consensual sex, frequently in young women or homosexual men. A 24-year-old woman came to our clinic complaining of asymptomatic red petechiae on the palate. There was cervical lymphadenopathy. Oral examination revealed small red spots on the soft palate, and patient confirmed the practice of fellatio. The differential diagnosis included syphilis and blood dyscrasias. The anamnesis was noncontributory. Seven days after cessation of fellatio the oral lesions resolved. The laboratory tests were within normal values. It is important that dentists know the oral manifestations of oral sex to include this clinical hypothesis in the diagnosis of palatal lesions.
ORAL AMYLOIDOSIS: 2 CASE REPORTS. PRISCILA ANA BRAGA DA SILVA ROCHA, RUTH TRAMONTANI RAMOS, GERALDO OLIVEIRA SILVA JUNIOR, MARILIA HEFFER CANTISAN ^ PIRES and, FABIO RAMOA