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Clinical experience of buccal fat pad in oral and maxillofacial surgery
1302
21st ICOMS 2013 - Abstracts: Oral Papers
T20.OR003
T20.OR005
How to write a paper for journal publication
Clinical experience of buccal fat pad in oral and maxillofacial surgery
G.
Dimitroulis 1,2
1 Dept
of Surgery, St. Vincent’s Hospital, University of Melbourne, Australia 2 Section Editor – International Journal Oral Maxillofacial Surgery Writing a paper for publication in peer review journals is a challenging endeavour that requires patience and experience. This lecture will present some practical hints as to how to write a paper that will attract favourable attention from journal reviewers and editors. It will also provide a journal editor’s perspective of the minimum requirements necessary for acceptance of papers for publication. http://dx.doi.org/10.1016/j.ijom.2013.07.439 T20.OR004 Oral infection as a risk factor for preeclampsia R. Elsharkawy 1,∗ , H. Elmonoufy 2 , M. Zaghloul 3 , D. Sabry 4 , O. Nouh 5
A. Hassani Tehran Azad University of Medical Sciences, Dental Branch, Iran BFP is special source of tissue for oral defect because of its location, rich vascularization and stem cells. Surgical anatomy and various applications of BFP flap for reconstruction of soft and hard tissue defects will discuss here. Some common applications of BFP flap, like closure of oro-antral and oro-nasal communications and Repair of cleft palate especially in second approach in failed ones and Covering of regional pathologic soft tissue defect such as oral sub mucous fibrosis or traumatic mucosal defects or regional pathologic bone tissue defect such as exposed bone or osteoradionecrosis lesions and as a biologic membrane for coverage and bone in case of bone augmentation in posterior alveolar ridge and Repair of large perforation of Schneiderian membrane in sinus lifting for simultaneous implant placement and also in TMJ reconstructions. Also, the BFP could be removed by lipectomy to improve aesthetic by midfacial cheek hollowing and it also can be used for coverage of nerve repair and to reduce strength of postoperative scar and producing adipose drive stem cell for tissue engineering. Surgical access to BFP via posterior maxillary vestibule and upper anterior mandibular ramus and anatomic considerations like endangered nerve and vessels are also discuss in detail.
1
Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Cairo University, Cairo, Egypt 2 Department of Periodontology, Oral Medicine and Oral Diagnosis, Faculty of Oral and Dental Surgery, Misr University for Science and Technology, Cairo, Egypt 3 Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt 4 Department of Medical Biochemistry, Faculty of Medicine, Cairo University, Cairo, Egypt 5 Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt Background: Maternal oral infection has been associated with preeclampsia. This study was done to explore this association. Methods: Forty preeclamptic women and 40 normotensive pregnant women, both having oral infection, were subjected to microbiological assessment of subgingival plaque samples, samples of pericoronal pseudo-pocket and placental samples on different culture media and multiplex PCR. Gingival crevicular fluid, saliva and serum of both groups were examined for presence of TNF-␣. Results: There were no significant differences between the two groups regarding oral samples’ organisms, revealed by culture and PCR, or as regards to blood samples’ organisms, revealed by culture. The total number of anaerobes in blood samples and placental samples was higher in preeclamptic group than controls. PCR results of placental samples of the preeclampsia group showed significantly higher prevalence of Aggregatibacter actinomycetemcomitans, Eikenella corrodens and Prevotella intermedia than that of the control. There was a significant difference between the two groups as regards to the level of TNF-␣ by ELISA where the P-value was 0.021. Conclusion: There was a relationship between chronic oral infection and preeclampsia. So, treatment of oral infection during pregnancy may represent a novel strategy to decrease the incidence of preeclampsia. Key words: oral infection; preeclampsia; PCR http://dx.doi.org/10.1016/j.ijom.2013.07.440
http://dx.doi.org/10.1016/j.ijom.2013.07.441 T20.OR006 Can Ki-67 predict aggressiveness and aid in the management of dentinogenic ghost cell tumours? H. Ishii ∗ , B. Evans University Hospital Southampton NHS Foundation Trust, United Kingdom Background: Dentinogenic ghost cell tumours (DGCTs) are a rare subset of the odontogenic tumours. These DGCTs are described as ‘locally invasive neoplasms characterized by ameloblastomalike islands of epithelial cells in a mature connective tissue stroma’.1 These lesions have been shown to behave more aggressively and have a higher recurrence rate than its less aggressive relative, the calcifying cystic odontogenic tumours (CCOTs). Materials and methods: Two patients with DGCTs – both located within the right maxilla – presenting to one surgical unit, are described. The excised specimens were analysed using H&E and several immunohistochemical stains, including Ki-67. Results: The tumour behaviour in the two patients differed. One tumour exhibited a more aggressive nature, necessitating a wider resection and complex reconstruction, compared to the other, where a simple excision sufficed. Morphologically, both tumours appeared similar. However, there were differences in the Ki-67 levels exhibited by each tumour. Conclusion: The potential significance of Ki-67 as a possible marker to tumour aggressiveness, first proposed by Gong et al.,2 is discussed in the light of clinical behaviour of these two cases. Key words: Ki-67; dentinogenic ghost cell tumours
References Praetorius, F., & Ledesma-Montes, C. (2005). Dentinogenic ghost cell tumour. In L. Barnes, J. W. Eveson, P. Reichart, & D. Sidransky (Eds.), World Health Organization classification of tumours. Pathology and genetics of head and neck tumours (p. 314). Lyon: IARC Press. Gong, Y., Wang, L., Wang, H., Li, T., & Chen, X. (2009). The expression of NF-kappaB, Ki-67 and MMP-9 in CCOT, DGCT and GCOC. Oral Ocol, 45(June (6)), 515–520. http://dx.doi.org/10.1016/j.ijom.2013.07.442
21st ICOMS 2013 - Abstracts: Oral Papers
T20.OR003
T20.OR005
How to write a paper for journal publication
Clinical experience of buccal fat pad in oral and maxillofacial surgery
G.
Dimitroulis 1,2
1 Dept
of Surgery, St. Vincent’s Hospital, University of Melbourne, Australia 2 Section Editor – International Journal Oral Maxillofacial Surgery Writing a paper for publication in peer review journals is a challenging endeavour that requires patience and experience. This lecture will present some practical hints as to how to write a paper that will attract favourable attention from journal reviewers and editors. It will also provide a journal editor’s perspective of the minimum requirements necessary for acceptance of papers for publication. http://dx.doi.org/10.1016/j.ijom.2013.07.439 T20.OR004 Oral infection as a risk factor for preeclampsia R. Elsharkawy 1,∗ , H. Elmonoufy 2 , M. Zaghloul 3 , D. Sabry 4 , O. Nouh 5
A. Hassani Tehran Azad University of Medical Sciences, Dental Branch, Iran BFP is special source of tissue for oral defect because of its location, rich vascularization and stem cells. Surgical anatomy and various applications of BFP flap for reconstruction of soft and hard tissue defects will discuss here. Some common applications of BFP flap, like closure of oro-antral and oro-nasal communications and Repair of cleft palate especially in second approach in failed ones and Covering of regional pathologic soft tissue defect such as oral sub mucous fibrosis or traumatic mucosal defects or regional pathologic bone tissue defect such as exposed bone or osteoradionecrosis lesions and as a biologic membrane for coverage and bone in case of bone augmentation in posterior alveolar ridge and Repair of large perforation of Schneiderian membrane in sinus lifting for simultaneous implant placement and also in TMJ reconstructions. Also, the BFP could be removed by lipectomy to improve aesthetic by midfacial cheek hollowing and it also can be used for coverage of nerve repair and to reduce strength of postoperative scar and producing adipose drive stem cell for tissue engineering. Surgical access to BFP via posterior maxillary vestibule and upper anterior mandibular ramus and anatomic considerations like endangered nerve and vessels are also discuss in detail.
1
Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Cairo University, Cairo, Egypt 2 Department of Periodontology, Oral Medicine and Oral Diagnosis, Faculty of Oral and Dental Surgery, Misr University for Science and Technology, Cairo, Egypt 3 Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt 4 Department of Medical Biochemistry, Faculty of Medicine, Cairo University, Cairo, Egypt 5 Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt Background: Maternal oral infection has been associated with preeclampsia. This study was done to explore this association. Methods: Forty preeclamptic women and 40 normotensive pregnant women, both having oral infection, were subjected to microbiological assessment of subgingival plaque samples, samples of pericoronal pseudo-pocket and placental samples on different culture media and multiplex PCR. Gingival crevicular fluid, saliva and serum of both groups were examined for presence of TNF-␣. Results: There were no significant differences between the two groups regarding oral samples’ organisms, revealed by culture and PCR, or as regards to blood samples’ organisms, revealed by culture. The total number of anaerobes in blood samples and placental samples was higher in preeclamptic group than controls. PCR results of placental samples of the preeclampsia group showed significantly higher prevalence of Aggregatibacter actinomycetemcomitans, Eikenella corrodens and Prevotella intermedia than that of the control. There was a significant difference between the two groups as regards to the level of TNF-␣ by ELISA where the P-value was 0.021. Conclusion: There was a relationship between chronic oral infection and preeclampsia. So, treatment of oral infection during pregnancy may represent a novel strategy to decrease the incidence of preeclampsia. Key words: oral infection; preeclampsia; PCR http://dx.doi.org/10.1016/j.ijom.2013.07.440
http://dx.doi.org/10.1016/j.ijom.2013.07.441 T20.OR006 Can Ki-67 predict aggressiveness and aid in the management of dentinogenic ghost cell tumours? H. Ishii ∗ , B. Evans University Hospital Southampton NHS Foundation Trust, United Kingdom Background: Dentinogenic ghost cell tumours (DGCTs) are a rare subset of the odontogenic tumours. These DGCTs are described as ‘locally invasive neoplasms characterized by ameloblastomalike islands of epithelial cells in a mature connective tissue stroma’.1 These lesions have been shown to behave more aggressively and have a higher recurrence rate than its less aggressive relative, the calcifying cystic odontogenic tumours (CCOTs). Materials and methods: Two patients with DGCTs – both located within the right maxilla – presenting to one surgical unit, are described. The excised specimens were analysed using H&E and several immunohistochemical stains, including Ki-67. Results: The tumour behaviour in the two patients differed. One tumour exhibited a more aggressive nature, necessitating a wider resection and complex reconstruction, compared to the other, where a simple excision sufficed. Morphologically, both tumours appeared similar. However, there were differences in the Ki-67 levels exhibited by each tumour. Conclusion: The potential significance of Ki-67 as a possible marker to tumour aggressiveness, first proposed by Gong et al.,2 is discussed in the light of clinical behaviour of these two cases. Key words: Ki-67; dentinogenic ghost cell tumours
References Praetorius, F., & Ledesma-Montes, C. (2005). Dentinogenic ghost cell tumour. In L. Barnes, J. W. Eveson, P. Reichart, & D. Sidransky (Eds.), World Health Organization classification of tumours. Pathology and genetics of head and neck tumours (p. 314). Lyon: IARC Press. Gong, Y., Wang, L., Wang, H., Li, T., & Chen, X. (2009). The expression of NF-kappaB, Ki-67 and MMP-9 in CCOT, DGCT and GCOC. Oral Ocol, 45(June (6)), 515–520. http://dx.doi.org/10.1016/j.ijom.2013.07.442