Clinical spectrum of postpartum renal failure

Autoimmunity

Lymphocytic

leukemia

Hyperimmunoglobulinemia

carcinoma

hyperparathyroidism

Parathyroid

Multiple endocrine

type I

in famil-

Reported here is the occurrence of parathyroid carcinoma in familial parathyroid hyperplasia or multiple endocrine adenomatosis, type I. In the patient described, hypercalcemia persisted through 8 years even though abnormal parathyroid tissue was removed from three separate sites in the neck. A fourth operation revealed implants of parathyroid carcinoma unilaterally in the left side of the neck. The patient’s brother and sister also had parathyroid hyperplasia, and his mother died of a pancreatic tumor of undocumented cell type. The patient himself had no evidence of pancreatic or pituitary tumor.

carcinoma

immunoassay

adenomatosis, hormone

Mallette LE, Bilezikian JP, Ketcham AS, Aurbach GD: Parathyroid ial hyperparathyroidism. Am J Med 57:642-648. 1974.

Familial

Parathyroid

Described here is a 44 year old woman with discoid lupus erythematosus in whom chronic lymphocytic leukemia of the 6 cell type with macroglobulinemia developed. Immunologic studies revealed suppressed thymus-dependent cell function, increased bone marrow-dependent cells of the immunoglobulin M class and increased null cells. Discussed are the pathogenesis and relation of lupus erythematosus to B cell malignancy with hyperimmunoglobulinemia.

Abdou NL, Abdou NI: Discoid lupus erythematosus with macroglobulinemia. Correlations between autoimmunity and B cell malignancy with hyperimmunoglobulinemia. Am J Med 57: 631-637, 1974

Macroglobulinemia

Lupus erythematosus

B cell malignancy

Enteritis

Vibrio parahemolyticus ulceration

due to Vibrio

M, Hayslett 1974.

JP: Clinical spectrum

Fibrin deposition anemia

of postpartum

Uremia

renal fail-

Four patients with postpartum renal failure are described with the typical hematologic and renal pathologic changes. Two had severe uremia, and two had a milder clinical course with complete restoration of renal function. All four showed changes suggestive of fibrin deposition in the renal vasculature. It is suggested that postpartum renal failure includes a spectrum of disease from fulminant renal failure with extensive fibrin deposition to minor renal dysfunction with minimal fibrin deposition.

Finkelstein FO, Kashgarian ure. Am J Med 57:649-654.

hemolytic

renal failure

Microangiopathic

Postpartum

Presented here are the clinical features in a case of enteritis due to Vibrio parahemolyticus. Superficial ulcerations of colonic mucosa were observed by sigmoidoscopy. Previously such damage had not been documented but inferred from the presence of red cells and leukocytes in the stools.

in enteritis

Food poisoning

Bolen JL, Zamiska SA, Greenough WB III: Clinical features parahemolyticus. Am J Med 57: 638-641, 1974.

Colonic mucosal