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Comparison of more than 3 years clinical outcomes between drug-eluting stents and coronary artery bypass graft for unprotected left main disease
S8
Oral Presentation Sessions / International Journal of Cardiology 163S2 (2013) S1–S30
A015 Comparison of more than 3 years clinical outcomes between drug-eluting stents and coronary artery bypass graft for unprotected left main disease
Others
D.X. Wang, C.H. Zhou, H. Liu, L.R. Yan, X.X. Zhang. Key Laboratory of Clinical Trial Research in Cardiovascular Drugs, Ministry of Health, State Key Laboratory of Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, China
A016 – Smoking Psychological predictors of stage of readiness to quit among Hong Kong Chinese smokers: the role of social acceptance of smoking by family
Purpose: We sought to perform a meta analysis to combine the available randomised and nonrandomised studies examine the clinical effect of drug-eluting stents (DES) and coronary artery bypass graft (CABG) in unprotected left main disease (UPLM) with more than 3 year follow-up. Methods: A systemic research was carried out in Pubmed, Embase, Cochrane library and scientific sessions of AHA, ACC and ESC (up to Oct 2012). All randomised and nonrandomised studies after ≥3 years of follow-up comparing DES and CABG in UPLM were included. In observational studies, risk adjusted hazard ratio (HR) or odds ratio (OR) were extracted. Sensitivity analyses and publication analyses were also performed to confirm the reliability of results. Results: 11 eligible studies (2 randomised, 9 nonrandomised) with 6858 subjects were identified and selected. Mortality, death/MI/stroke and target vessel revascularizaton (TVR) were focused. Pooled analysis revealed that there was no statistical significant difference between DES and CABG in mortality (OR=0.95, 95% confidential interval [CI]: 0.81 to 1.13, P=0.586, heterogeniety test: 0.0%; Fig. 1) and death/MI/stroke (OR=0.94, 95% CI: 0.80 to 1.11, P=0.473, heterogeniety test: 0.0%).However, compared with CABG, DES had a significant increased incidence of TVR (Random-effect model, OR=3.56, 95% CI: 2.66 to 4.71, P<0.001, heterogeniety test: 45.9%). No evidence of significant publication bias was observed in mortality (Begg’s test, P=0.325; Egger’s test, P=0.407). Sensitivity analysis of mortality excluding each included study at one time revealed that most individual study was consisted with the direction and size of the overall effect (all P>0.1).
D.Y.P. Leung 1 , E.M.L. Wong 1 , S.S.C. Chan 2 . 1 The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China; 2 School of Nursing, The University of Hong Kong, Hong Kong, China Purpose: The Attitude-Social Influence-Efficacy (ASE) model has been used to gain insight into the determinants and guide the development of interventions for smoking cessation. In addition, a particular personality trait, conscientiousness, was also reported affecting motivation to quit among smokers. This study aims to explore the ASE and personality predictors of readiness to quit smoking among Hong Kong Chinese smokers. Methods: A longitudinal study was conducted with 309 Hong Kong residents who aged >15 years old and smoked ≥1 cigarette in a week in the past 6 months in Feb-Dec 2010. A path model linking stage of readiness to quit at 3-month to eight baseline variables: priority of quitting, social support, social acceptance of smoking by family, social acceptance of smoking by friends, self-efficacy to resist smoking due to internal and external stimuli, and stage of readiness to quit, and conscientiousness was fitted to the data. Results: We successfully followed-up 219 (70.9%) participants and 203 (92.7%) had provided completed responses in all the variables in the analysis. Their mean age was 27.6±12.4 years, 49.8% were male, 76.4% were married and 69.9% had education level of ≥ Form 4–5. A good fit to the data was obtained (R-χ2 =21.15, df=21, R-CFI=0.999, SRMR=0.064, R-RMSEA=0.006). Stage of readiness to quit at 3-months was predicted significantly by stage of readiness (β=0.73) and social acceptance of smoking by family (β= –0.16) but not self-efficacy to resist smoking due to internal (β=0.08) and external stimuli (β= –0.07) at baseline. Conscientiousness, social support, and priority of quitting have indirect effects on stage of readiness to quit at 3 months. Conclusion: The results suggest that social acceptance of smoking by family seems to play a more important role in motivating smokers to quit. While current smoking cessation programmes focus mainly on enhancing self-efficacy to resist smoking, future development in cessation interventions can also include smokers’ family members by stopping the smokers to smoke around them.
A017 – Cardiovascular Multimorbidity Factors associated with cardiovascular multimorbidity among primary care patients in southern China
Figure 1
Conclusion: Based on the available evidence, after long-term follow up, the mortality and composite outcome are similar between DES and CABG in patients with UPLM, however, incidence of TVR is still high in DES comparing with CABG.
H.H.X. Wang 1 , M.C.S. Wong 1 , S.Y.S. Wong 1 , J.L. Tang 1 , B.P. Yan 2 , C.M. Yu 2 , J.J. Wang 3 , D.K.T. Li 4 , S.M. Griffiths 1 . 1 School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong; 2 Division of Cardiology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong; 3 School of Public Health, Guangzhou Medical University, P.R. China; 4 Bauhinia Foundation Research Centre, Hong Kong Purpose: Management of the rising prevalence of long-term conditions is one of the major challenges facing China’s current primary care reform. Better understanding of factors associated with cardiovascular multimorbidity is necessary to develop a comprehensive strategy to support primary care physicians in China to provide patient-centred and continuous care. This study aimed to examine factors on individual socio-economic status in relation to the preva-
Oral Presentation Sessions / International Journal of Cardiology 163S2 (2013) S1–S30
A015 Comparison of more than 3 years clinical outcomes between drug-eluting stents and coronary artery bypass graft for unprotected left main disease
Others
D.X. Wang, C.H. Zhou, H. Liu, L.R. Yan, X.X. Zhang. Key Laboratory of Clinical Trial Research in Cardiovascular Drugs, Ministry of Health, State Key Laboratory of Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, China
A016 – Smoking Psychological predictors of stage of readiness to quit among Hong Kong Chinese smokers: the role of social acceptance of smoking by family
Purpose: We sought to perform a meta analysis to combine the available randomised and nonrandomised studies examine the clinical effect of drug-eluting stents (DES) and coronary artery bypass graft (CABG) in unprotected left main disease (UPLM) with more than 3 year follow-up. Methods: A systemic research was carried out in Pubmed, Embase, Cochrane library and scientific sessions of AHA, ACC and ESC (up to Oct 2012). All randomised and nonrandomised studies after ≥3 years of follow-up comparing DES and CABG in UPLM were included. In observational studies, risk adjusted hazard ratio (HR) or odds ratio (OR) were extracted. Sensitivity analyses and publication analyses were also performed to confirm the reliability of results. Results: 11 eligible studies (2 randomised, 9 nonrandomised) with 6858 subjects were identified and selected. Mortality, death/MI/stroke and target vessel revascularizaton (TVR) were focused. Pooled analysis revealed that there was no statistical significant difference between DES and CABG in mortality (OR=0.95, 95% confidential interval [CI]: 0.81 to 1.13, P=0.586, heterogeniety test: 0.0%; Fig. 1) and death/MI/stroke (OR=0.94, 95% CI: 0.80 to 1.11, P=0.473, heterogeniety test: 0.0%).However, compared with CABG, DES had a significant increased incidence of TVR (Random-effect model, OR=3.56, 95% CI: 2.66 to 4.71, P<0.001, heterogeniety test: 45.9%). No evidence of significant publication bias was observed in mortality (Begg’s test, P=0.325; Egger’s test, P=0.407). Sensitivity analysis of mortality excluding each included study at one time revealed that most individual study was consisted with the direction and size of the overall effect (all P>0.1).
D.Y.P. Leung 1 , E.M.L. Wong 1 , S.S.C. Chan 2 . 1 The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China; 2 School of Nursing, The University of Hong Kong, Hong Kong, China Purpose: The Attitude-Social Influence-Efficacy (ASE) model has been used to gain insight into the determinants and guide the development of interventions for smoking cessation. In addition, a particular personality trait, conscientiousness, was also reported affecting motivation to quit among smokers. This study aims to explore the ASE and personality predictors of readiness to quit smoking among Hong Kong Chinese smokers. Methods: A longitudinal study was conducted with 309 Hong Kong residents who aged >15 years old and smoked ≥1 cigarette in a week in the past 6 months in Feb-Dec 2010. A path model linking stage of readiness to quit at 3-month to eight baseline variables: priority of quitting, social support, social acceptance of smoking by family, social acceptance of smoking by friends, self-efficacy to resist smoking due to internal and external stimuli, and stage of readiness to quit, and conscientiousness was fitted to the data. Results: We successfully followed-up 219 (70.9%) participants and 203 (92.7%) had provided completed responses in all the variables in the analysis. Their mean age was 27.6±12.4 years, 49.8% were male, 76.4% were married and 69.9% had education level of ≥ Form 4–5. A good fit to the data was obtained (R-χ2 =21.15, df=21, R-CFI=0.999, SRMR=0.064, R-RMSEA=0.006). Stage of readiness to quit at 3-months was predicted significantly by stage of readiness (β=0.73) and social acceptance of smoking by family (β= –0.16) but not self-efficacy to resist smoking due to internal (β=0.08) and external stimuli (β= –0.07) at baseline. Conscientiousness, social support, and priority of quitting have indirect effects on stage of readiness to quit at 3 months. Conclusion: The results suggest that social acceptance of smoking by family seems to play a more important role in motivating smokers to quit. While current smoking cessation programmes focus mainly on enhancing self-efficacy to resist smoking, future development in cessation interventions can also include smokers’ family members by stopping the smokers to smoke around them.
A017 – Cardiovascular Multimorbidity Factors associated with cardiovascular multimorbidity among primary care patients in southern China
Figure 1
Conclusion: Based on the available evidence, after long-term follow up, the mortality and composite outcome are similar between DES and CABG in patients with UPLM, however, incidence of TVR is still high in DES comparing with CABG.
H.H.X. Wang 1 , M.C.S. Wong 1 , S.Y.S. Wong 1 , J.L. Tang 1 , B.P. Yan 2 , C.M. Yu 2 , J.J. Wang 3 , D.K.T. Li 4 , S.M. Griffiths 1 . 1 School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong; 2 Division of Cardiology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong; 3 School of Public Health, Guangzhou Medical University, P.R. China; 4 Bauhinia Foundation Research Centre, Hong Kong Purpose: Management of the rising prevalence of long-term conditions is one of the major challenges facing China’s current primary care reform. Better understanding of factors associated with cardiovascular multimorbidity is necessary to develop a comprehensive strategy to support primary care physicians in China to provide patient-centred and continuous care. This study aimed to examine factors on individual socio-economic status in relation to the preva-