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deficits with abstract reasoning and problem solvmg, and visual discrimination deficits. These cases highlight the idiopathic nature of responses to pathological exposure to neurotoxins, beyond a core set of symptoms. The importance of comprehensive evaluation to detect idiosyncratic responses. Future research should not be limited by previous reports of specific deficits. 32. Hazlewood,
M. G., Souheaver, G. T., 8r Cochran, W. University of Arkansas for Medical Sciences, J. L. McClellan V, A. Medical Center, & University of Arkansas, Rehabilitation Division Comparison of the Neurobehavioral Cognitive Status Examination and the Mini-Mental Status Examination in Cases of Suspected Aizheimer’s Panents. Accurate assessment of cognitive decline of geriatric patients in the assessment of dementia is an increasing diagnostic concern. Use of relatively brief tests have increased and often with little or incomplete validation. Recently, Kiernan and co-workers (1987) developed a screening instrument designed to assess several aspects of higher-brain functions, rather than the limited measures of the Mini-Mental State Examination (MMSE) published by Folstein et. al. (1975). The Neurobehavioral Cognitive Status Examination (NCSE) offers both qualitative and quantitative measures of severity of impairment across various language and problem-solving factors. The current study compares the NCSE with the MMSE in elderly patients (N = 40) being screened in a Dementia Clinic at a large university medical center. Subjects were consecutive admissions; over age 65; and underwent comprehensive neurological examination, including CT/MRI studies. All met DSM III-R criteria for primary degenerative dementia. Results describe the frequently occurring NCSE profiles for these ALzheimer’s patients and examine performance declines related to: age at onset, education, and psychosocial functioning.
33. Heck, Edward, T. & Cobb, William E. Endocrine Division, England Medical Center Hospitals Cognitive and Affective Symptoms in Stein-Leventhal Syndrome.
New
Stein-Leventhal syndrome is a chronic anovulatory disorder characterized by hirsutism, menstrual irregularity, infertility, and enlarged multicystic ovaries. It was first described in 1934. Since then, the relationship between SteinLeventhal syndrome and psychological disorder has been the subject of few studies and no study has reported improvement in psychological functioning during treatment. This study investigated disorders of cognition and mood regulation associated with Stein-Leventhal syndrome. At intake, all 15 subjects exhibited depression and reduced abstract thinking ability on a battery of cognitive and personality tests. All subjects were then treated with the dopamine agonist, bromocriptine. Three months later the test battery was re-administered. Both mood and cognition improved significantly after treatment with bromocriptine. 2.he