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Comparison of treatment of severe asthma by electrophoresis of epinephrine with other methods
Selected Abstracts Asthma and Hay Fever UNDER
TIIE
DIRECTION
Comparison of Treatment With Other Methods.
OF S~~WFX, BERNSTEIN,
M. FEINBERG, M.D., M.D., CHICAGO
of Severe Asthma Abramson,
H.
9.:
XXI
THEODORE
by Electrophoresis Arch.
Phys.
R.
of Epinephrine
Therapy
21:
261,
1940.
The author treated a group of fourteen patients with severe asthma by means of electrophoresis of epinephrine hydrochloride, 1 per cent. A single treatment usually consisted of the application to three successive skin areas, each from 30 to 50 sq. cm. in area, and each area being treated for from ten to fifteen minutes. Blanching occurs, \vhich serves to reduce the rate of absorption of the epinephrine from the skin site. The author estimates that an ahsorption rate of approximately 1 mg. per hour may be achieved with the method outlined. fu’o constitutional reactions were observed in the first thirty-five persons upon whom the electrophoresis technique was used. Also, there was no rise in blood pressure in normal persons. It was observed that this method gave relief in some patients who had been considered adrenaline fast, and also in some in whom subcutaneous injections of adrenaline caused nervous reactions. During the period of electrophoresis treatment, administration of epinephrine in oil or aminophyllin intravenously could be omitted.
Bronchial Asthma : New Use For an Old Remedy. State J. Med. 40: 483, 1940.
King,
G. S.:
New York
The author has used intravenous injections of strontium bromide, 15 grains per 10 c.c., for the treatment of the symptoms of asthma, with good results. Many of his patients who had become tolerant to adrenaline, ephedrine, and morphine experienced immediate relief when the drug was injected slowly. The administration of strontium bromide is generally accompanied by a diffused feeling of warmth. The discomfiture is practically nullified if the solution is injected slowly. Usually before the entire 10 C.C. is injected the patient is free of symptoms. If no re. sponse is obtained to the first injection, a second or third may be given. The author has never seen an anaphylactic reaction due to the administration of the drug intravenously, other than the local or skin manifestations due to bromide intolerance.
Pollen Asthma Pennsylvania
and Hay Fever in Children. M.
J. 43:
1137,
Copeland,
S. C., and
Beating,
J. P.:
19-10.
This is a clinical analysis of fifty-eight cases of pollen asthma and hay fever in children observed for from one to five years. Only six had pure hay fever; twenty-eight had pollen asthma, and twenty-four had both asthma and hay fever. The age of onset was as early as 8 months, and in thirty-eight children symptoms were evident by the preschool age. A positive past medical history of allergy, as evidenced by asthma, eczema, and urticaria, was obtained in 72 per cent of the
TIIE
DIRECTION
Comparison of Treatment With Other Methods.
OF S~~WFX, BERNSTEIN,
M. FEINBERG, M.D., M.D., CHICAGO
of Severe Asthma Abramson,
H.
9.:
XXI
THEODORE
by Electrophoresis Arch.
Phys.
R.
of Epinephrine
Therapy
21:
261,
1940.
The author treated a group of fourteen patients with severe asthma by means of electrophoresis of epinephrine hydrochloride, 1 per cent. A single treatment usually consisted of the application to three successive skin areas, each from 30 to 50 sq. cm. in area, and each area being treated for from ten to fifteen minutes. Blanching occurs, \vhich serves to reduce the rate of absorption of the epinephrine from the skin site. The author estimates that an ahsorption rate of approximately 1 mg. per hour may be achieved with the method outlined. fu’o constitutional reactions were observed in the first thirty-five persons upon whom the electrophoresis technique was used. Also, there was no rise in blood pressure in normal persons. It was observed that this method gave relief in some patients who had been considered adrenaline fast, and also in some in whom subcutaneous injections of adrenaline caused nervous reactions. During the period of electrophoresis treatment, administration of epinephrine in oil or aminophyllin intravenously could be omitted.
Bronchial Asthma : New Use For an Old Remedy. State J. Med. 40: 483, 1940.
King,
G. S.:
New York
The author has used intravenous injections of strontium bromide, 15 grains per 10 c.c., for the treatment of the symptoms of asthma, with good results. Many of his patients who had become tolerant to adrenaline, ephedrine, and morphine experienced immediate relief when the drug was injected slowly. The administration of strontium bromide is generally accompanied by a diffused feeling of warmth. The discomfiture is practically nullified if the solution is injected slowly. Usually before the entire 10 C.C. is injected the patient is free of symptoms. If no re. sponse is obtained to the first injection, a second or third may be given. The author has never seen an anaphylactic reaction due to the administration of the drug intravenously, other than the local or skin manifestations due to bromide intolerance.
Pollen Asthma Pennsylvania
and Hay Fever in Children. M.
J. 43:
1137,
Copeland,
S. C., and
Beating,
J. P.:
19-10.
This is a clinical analysis of fifty-eight cases of pollen asthma and hay fever in children observed for from one to five years. Only six had pure hay fever; twenty-eight had pollen asthma, and twenty-four had both asthma and hay fever. The age of onset was as early as 8 months, and in thirty-eight children symptoms were evident by the preschool age. A positive past medical history of allergy, as evidenced by asthma, eczema, and urticaria, was obtained in 72 per cent of the