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Composition and method for investigating alimentary functions
Nucl. Int.
Med.
Biol.
J. Radiat.
Pergamon
Journals
Vo1.15. Appl. Ltd.
No.1,
Instrum. Printed
pp.i-iv, Part
1988
B
in Great Britain NEW PATENTS
This Section contains abstracts and, where appropriate, illustrations of recently issued United States patents and published patent applications filed from over 30 countries under the Patent Cooperation Treaty. This information was obtained from recent additions to the Pergamon PATSEARCH” online database in accordance with interest profiles developed by the Editors. Further information about Pergamon PATSEARCH@ can be obtained from Pergamon Orbit InfoLine Inc., 8000 Westpark Drive, McLean, Virginia 22102 U.S.A. Copies of complete patents announced in this Section are available from Pergamon Orbit InfoLine Inc. for $8 per copy. Payment with order is required. Orders outside North America add $2 for air postage. Order by patent number for Pergamon Orbit InfoLine only.
4657755 COMPOSITION AND METHOD FOR INVESTIGATING ALIMENTARY FUNCTIONS
volunteers (A) compared to the emptying from a person with the &37 Giesskannen+ 38 +0 phenomenon (B).(B).. . ..n (B).
4657928
Finn N Christensen, Jens R Jensen, Hell Bechgaard, Copenhagen, Denmark assigned to A/S Alfred Benzon
ORGANIC COPPER COMPLEXES AS RADIOPROTECTANTS
Enterically administrable diagnostic compositions for investigating alimentary functions comprising multiple units of a size of at the most 5 mm, preferably between 0.5 and 1.3 mm in particular between 0.7 and 1.0 mm, each unit comprising a tracer substance binding agent (such as an ion exchange resin) with a radioactive tracer substance with a half-life of at the most 5 days, in particular 99mTc, 113mln, 111In and 129Cs, is associated. The tracer substance binding agent is being formulated with pharmaceutically acceptable excipients, in particular granulating excipients, in such a way that the exposure of the gastrointestinal mucosa to the tracer substance binding agent is reduced and that the units do not disintegrate during the passage through the gastrointestinal tract. Preferred units comprise cross-sectionally substantially homogeneous multi-component cores in which the tracer substance binding agent is granulated with one or more excipients and which are optionally coated. Preferred units comprise cross-sectionally substantially homogeneous multi-component cores made by granulating the tracer-binding agent surface properties. Tracer substances are normally present in an amount from about 2 to about 20% by weight, preferably from about 5 to about 10% by weight, calculated on the units. Due to low leaching and the non-disintegrating properties, the composition can be used to investigate gastric emptying also of the last 20% of a food bolus, cf. FIG. 2 which illustrates the average gastric emptying pattern for 7 healthy
John R J Sorenson assigned to International Copper Research Association Inc Methods are described for using organic copper complexes or their solvates, which exhibit superoxide dismutase activity and act as superoxide radical scavengers, as radioprotectants to protect mammalian cells from damage caused by gamma- or x-irradiation. Treatment can result in the protection of normal tissues in cancer patients undergoing radiotherapy and in the protection of individuals who may be at risk with regard to hazardous effects of exposure to occupational or environmental ionizing radiation.
4659477 FIXATION OF ANIONIC MATERIALS WITH A COMPLEXING AGENT Pedro B Macedo, Aaro Barkatt assigned to Macedo Pedro B; Litovitz Theodore A A composition comprising a support such as a porous silicate glass or silica gel or charcoal having interconnected pores and containing heavy metal cations of mercury, thallium, silver, platinum, palladium, lead or copper capable of forming a stable complex with an anion bonded to the support. The preferred heavy metal cation
Med.
Biol.
J. Radiat.
Pergamon
Journals
Vo1.15. Appl. Ltd.
No.1,
Instrum. Printed
pp.i-iv, Part
1988
B
in Great Britain NEW PATENTS
This Section contains abstracts and, where appropriate, illustrations of recently issued United States patents and published patent applications filed from over 30 countries under the Patent Cooperation Treaty. This information was obtained from recent additions to the Pergamon PATSEARCH” online database in accordance with interest profiles developed by the Editors. Further information about Pergamon PATSEARCH@ can be obtained from Pergamon Orbit InfoLine Inc., 8000 Westpark Drive, McLean, Virginia 22102 U.S.A. Copies of complete patents announced in this Section are available from Pergamon Orbit InfoLine Inc. for $8 per copy. Payment with order is required. Orders outside North America add $2 for air postage. Order by patent number for Pergamon Orbit InfoLine only.
4657755 COMPOSITION AND METHOD FOR INVESTIGATING ALIMENTARY FUNCTIONS
volunteers (A) compared to the emptying from a person with the &37 Giesskannen+ 38 +0 phenomenon (B).(B).. . ..n (B).
4657928
Finn N Christensen, Jens R Jensen, Hell Bechgaard, Copenhagen, Denmark assigned to A/S Alfred Benzon
ORGANIC COPPER COMPLEXES AS RADIOPROTECTANTS
Enterically administrable diagnostic compositions for investigating alimentary functions comprising multiple units of a size of at the most 5 mm, preferably between 0.5 and 1.3 mm in particular between 0.7 and 1.0 mm, each unit comprising a tracer substance binding agent (such as an ion exchange resin) with a radioactive tracer substance with a half-life of at the most 5 days, in particular 99mTc, 113mln, 111In and 129Cs, is associated. The tracer substance binding agent is being formulated with pharmaceutically acceptable excipients, in particular granulating excipients, in such a way that the exposure of the gastrointestinal mucosa to the tracer substance binding agent is reduced and that the units do not disintegrate during the passage through the gastrointestinal tract. Preferred units comprise cross-sectionally substantially homogeneous multi-component cores in which the tracer substance binding agent is granulated with one or more excipients and which are optionally coated. Preferred units comprise cross-sectionally substantially homogeneous multi-component cores made by granulating the tracer-binding agent surface properties. Tracer substances are normally present in an amount from about 2 to about 20% by weight, preferably from about 5 to about 10% by weight, calculated on the units. Due to low leaching and the non-disintegrating properties, the composition can be used to investigate gastric emptying also of the last 20% of a food bolus, cf. FIG. 2 which illustrates the average gastric emptying pattern for 7 healthy
John R J Sorenson assigned to International Copper Research Association Inc Methods are described for using organic copper complexes or their solvates, which exhibit superoxide dismutase activity and act as superoxide radical scavengers, as radioprotectants to protect mammalian cells from damage caused by gamma- or x-irradiation. Treatment can result in the protection of normal tissues in cancer patients undergoing radiotherapy and in the protection of individuals who may be at risk with regard to hazardous effects of exposure to occupational or environmental ionizing radiation.
4659477 FIXATION OF ANIONIC MATERIALS WITH A COMPLEXING AGENT Pedro B Macedo, Aaro Barkatt assigned to Macedo Pedro B; Litovitz Theodore A A composition comprising a support such as a porous silicate glass or silica gel or charcoal having interconnected pores and containing heavy metal cations of mercury, thallium, silver, platinum, palladium, lead or copper capable of forming a stable complex with an anion bonded to the support. The preferred heavy metal cation