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Congenital Buphthalmos
CONGENITAL BUPHTHALMOS. HARRY VANDERBILT W U R D E M A N N , M . D . , Sc.D.,
F.A.C.S.
SEATTLE, W.«iSHINGTON. Early cases of buphthalmos rarely come to histologic examination. This is a brief case history and report of postmortem findings of a child dying at the age of three months. The illustrations show the general condition of the eye, the development of the ciliary region, and a section of the greatly enlarged thymus gland.
A. C , age 3 months. Father 55 years, mother 50; four other healthy children. Brought to me June 15,
thalmos; pupils fully dilated; lens partially opaque; blue sclera. Had light attack "supposed to be pneumonia" 3
Fig. 1.— Buplithalmos, Wurdeniann's case, showing thinning of section of globe of all ocular coats, anti incomplete development of ciliary body and iris!
1926: had not been discoxered to be blind until my examination on that date. Accoucheur had difficulty in getting child to breathe; weighed about three pounds; rapidly increased in weight; acquired protuberant abdomen and head enlarged. Diagnosis: Eyes, congenital buph761
weeks before. Body shows evidences of cretinism; splay fingers; defective development of big toes; protuberant abdomen; frontal bosses protuberant; external ears poorly developed; occipital and pariental spaces wide between bones of skull; evidences of rickets. About June 18th had great
762
Η. V. W U R D E M A N N
difficulty in breathing; developed Cheyne-Stokes hreathing. Died eve ning June 22d from heart failure. Postmortem June 24 showed per forate foramen ovale of the heart; greatly enlarged thymus gland, a lobe
Microscopic examination—Thymus— Shows an unusually large number of keratinized Hassall's corpuscles. Round cell elements appear essentially normal. Lung—Shows incomplete aeration; partial atelectasis. G . R. CALLENDER.
Fig. 2.—Buphthalmos section thru ciliary region.
of which impinged on the heart. A b domen protuberant. Belly and skull not opened. Left eyeball, thymus and portion of lung removed. Report War Department Army Medical Museum. Gross description—Small, partially collapsed eye, cornea appearing larger than normal proportionately.
PATHOLOGIC REPORT:
Eye
of
infant
showing incomplete aniridia. Filtration angle bridged by embryonic tissue. Ligamentum pectinatum is in embyronic stage of development. Pos terior part of eye is normal. Cornea measures 12 mm. in diameter, abnor mally large. F. H.
VERHOEFF.
F.A.C.S.
SEATTLE, W.«iSHINGTON. Early cases of buphthalmos rarely come to histologic examination. This is a brief case history and report of postmortem findings of a child dying at the age of three months. The illustrations show the general condition of the eye, the development of the ciliary region, and a section of the greatly enlarged thymus gland.
A. C , age 3 months. Father 55 years, mother 50; four other healthy children. Brought to me June 15,
thalmos; pupils fully dilated; lens partially opaque; blue sclera. Had light attack "supposed to be pneumonia" 3
Fig. 1.— Buplithalmos, Wurdeniann's case, showing thinning of section of globe of all ocular coats, anti incomplete development of ciliary body and iris!
1926: had not been discoxered to be blind until my examination on that date. Accoucheur had difficulty in getting child to breathe; weighed about three pounds; rapidly increased in weight; acquired protuberant abdomen and head enlarged. Diagnosis: Eyes, congenital buph761
weeks before. Body shows evidences of cretinism; splay fingers; defective development of big toes; protuberant abdomen; frontal bosses protuberant; external ears poorly developed; occipital and pariental spaces wide between bones of skull; evidences of rickets. About June 18th had great
762
Η. V. W U R D E M A N N
difficulty in breathing; developed Cheyne-Stokes hreathing. Died eve ning June 22d from heart failure. Postmortem June 24 showed per forate foramen ovale of the heart; greatly enlarged thymus gland, a lobe
Microscopic examination—Thymus— Shows an unusually large number of keratinized Hassall's corpuscles. Round cell elements appear essentially normal. Lung—Shows incomplete aeration; partial atelectasis. G . R. CALLENDER.
Fig. 2.—Buphthalmos section thru ciliary region.
of which impinged on the heart. A b domen protuberant. Belly and skull not opened. Left eyeball, thymus and portion of lung removed. Report War Department Army Medical Museum. Gross description—Small, partially collapsed eye, cornea appearing larger than normal proportionately.
PATHOLOGIC REPORT:
Eye
of
infant
showing incomplete aniridia. Filtration angle bridged by embryonic tissue. Ligamentum pectinatum is in embyronic stage of development. Pos terior part of eye is normal. Cornea measures 12 mm. in diameter, abnor mally large. F. H.
VERHOEFF.