- Email: [email protected]
Conjunctival Intraepithelial Neoplasia
Peters et al
Threat to Fixation and Visual Impairment in Glaucoma
Footnotes and Financial Disclosures Originally received: August 18, 2014. Final revision: November 24, 2014. Accepted: December 4, 2014. Available online: December 20, 2014.
and Development Foundation. The sponsor or funding organization had no role in the design or conduct of this research. Manuscript no. 2014-1334.
Department of Ophthalmology, Lund University, Skåne University Hospital, Malmö, Sweden. Financial Disclosure(s): The author(s) have made the following disclosure(s): B.B.: Consultant e Carl Zeiss Meditec. A.H.: Consultant e Carl Zeiss Meditec, Allergan, Alcon; Speakers Bureau e Allergan, Santen, MSD; received royalties and payment for the development of educational presentations for Carl Zeiss Meditec and Allergan.
Abbreviations and Acronyms: AMD ¼ age-related macular degeneration; CI ¼ confidence interval; dB ¼ decibels; IOP ¼ intraocular pressure; MD ¼ mean deviation; OR ¼ odds ratio; PEXG ¼ pseudoexfoliation glaucoma; POAG ¼ primary open-angle glaucoma; TTF ¼ threat to fixation; VA ¼ visual acuity; VF ¼ visual field; VFL ¼ visual field loss. Correspondence: Dorothea Peters, MD, Department of Clinical Sciences Malmö, Ophthalmology, Lund University, Skåne University Hospital, SE-20502 Malmö, Sweden. E-mail: [email protected].
Supported by the Herman Järnhardt Foundation, Malmö; the Foundation for Visually Impaired in Former Malmöhus County, Malmö; Crown Princess Margareta’s Foundation, Stockholm; and Skåne County Council’s Research
Pictures & Perspectives Conjunctival Intraepithelial Neoplasia Conjunctival intraepithelial neoplasia (CIN) in a patient with a history of basal cell carcinoma. He noticed a red lesion on his conjunctiva that developed over 4e5 months before presentation (Fig 1). Histopathology revealed conjunctiva with full-thickness replacement of epithelial layers with mildly dysplastic cells (Fig 2), exhibiting nuclear pleomorphism and dyskeratosis (asterisks). The cells had a low nucleus to cytoplasm ratio and a few mitotic figures.
KRISHNA R. SURAPANENI, MD SARAH M. NEHLS, MD HEATHER D. POTTER, MD University of Wisconsin e Madison, Department of Ophthalmology and Visual Sciences, Madison, Wisconsin
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Threat to Fixation and Visual Impairment in Glaucoma
Footnotes and Financial Disclosures Originally received: August 18, 2014. Final revision: November 24, 2014. Accepted: December 4, 2014. Available online: December 20, 2014.
and Development Foundation. The sponsor or funding organization had no role in the design or conduct of this research. Manuscript no. 2014-1334.
Department of Ophthalmology, Lund University, Skåne University Hospital, Malmö, Sweden. Financial Disclosure(s): The author(s) have made the following disclosure(s): B.B.: Consultant e Carl Zeiss Meditec. A.H.: Consultant e Carl Zeiss Meditec, Allergan, Alcon; Speakers Bureau e Allergan, Santen, MSD; received royalties and payment for the development of educational presentations for Carl Zeiss Meditec and Allergan.
Abbreviations and Acronyms: AMD ¼ age-related macular degeneration; CI ¼ confidence interval; dB ¼ decibels; IOP ¼ intraocular pressure; MD ¼ mean deviation; OR ¼ odds ratio; PEXG ¼ pseudoexfoliation glaucoma; POAG ¼ primary open-angle glaucoma; TTF ¼ threat to fixation; VA ¼ visual acuity; VF ¼ visual field; VFL ¼ visual field loss. Correspondence: Dorothea Peters, MD, Department of Clinical Sciences Malmö, Ophthalmology, Lund University, Skåne University Hospital, SE-20502 Malmö, Sweden. E-mail: [email protected].
Supported by the Herman Järnhardt Foundation, Malmö; the Foundation for Visually Impaired in Former Malmöhus County, Malmö; Crown Princess Margareta’s Foundation, Stockholm; and Skåne County Council’s Research
Pictures & Perspectives Conjunctival Intraepithelial Neoplasia Conjunctival intraepithelial neoplasia (CIN) in a patient with a history of basal cell carcinoma. He noticed a red lesion on his conjunctiva that developed over 4e5 months before presentation (Fig 1). Histopathology revealed conjunctiva with full-thickness replacement of epithelial layers with mildly dysplastic cells (Fig 2), exhibiting nuclear pleomorphism and dyskeratosis (asterisks). The cells had a low nucleus to cytoplasm ratio and a few mitotic figures.
KRISHNA R. SURAPANENI, MD SARAH M. NEHLS, MD HEATHER D. POTTER, MD University of Wisconsin e Madison, Department of Ophthalmology and Visual Sciences, Madison, Wisconsin
1039