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Contact dermatitis from dental disinfectant wipes
304
Information Section
100 ppm N,N-dimethylethanolamine, a concentration which was overtly maternally toxic. No effects on the offspring were seen at 30 ppm, although maternal toxicity persisted at 10 ppm, the lowest concentration tested (Leung et al., ]ournal of Applied Toxicology 1996, 16, 533).
146 patients (aged 13-72 yr) over a 3-yr period. Positive allergic reactions were observed in 34 (23.2%) patients, 33 showing sensitivity to oleyl alcohol Three patients reacted to the myristyl, and two to the stearyl alcohol (Tosti et aL, Contact Dermatitis 1996, 35, 287).
Occupational dermatitis from hydralazine and bendroflumethiazide
Allergy to disodium ricinoleamido MEA-sulfosuccinate
Propranolol, hydralazine and bendroflumethiazide were found to cause occupational eczema on the hands, forearms and armpits in a 54-yr-old Portuguese worker employed for the last 9 yr in drug synthesis. New products had been introduced 9 months before onset of symptoms. Patch tests with propranolol, hydralazine (both at 0.1% in petrolatum), and bendroflumethiazide (2.0% in petrolatum) gave positive reactions. Although previous cases of occupational contact dermatitis from propranolol have been reported, the investigators claimed this to be the first from hydralazine and bendroflumethiazide (Pereira et a£, Contact Dermatitis 1996, 35, 303).
A 38-yr-old UK patient who developed dermatitis of the head and neck, starting "a few hours after~ using a new shampoo, reacted positively in patch tests to 0.01% disodium ricinoleamido MEAsulfosuccinate, an anionic surfactant found in various hairdressing products, and in the new shampoo at 0.8%. Although there have been several reports of allergic reactions from cocamidopropyl betaine (a similarly used surfactant), the investigators suggest that this might be the first from disodium ricinoleamido MEA-sulfosuccinate ~Tan et al., Contact Dermatitis 1996, 35, 307).
Contact dermatitis due to ETMDQ
Hand dermatitis to N-benzyl-N,N-dihydroxyethyl-N-cocosalkyl-ammonium chloride (a quaternary ammonium compound present in disinfectant wipes used in dentistry) has been reported in a 25-yr-old Italian woman. She had suffered the problem for the last year of her 3-yr career as a dental nurse. Patch tests with a 0.01% aqueous sohtion confirmed her allergy. The investigators were "not aware of other cases of contact sensitization reported to this compound~ (Placucci et al., Contact Dermatitis 1996, 35, 306).
What is claimed to be the first report of sensitization to 6-ethoxy-2,2,4-trimethyl-l,2dihydroquinoline (a rubber antioxidant) describes leg and foot dermatitis in Japanese rice farmers who wear rubber boots for long periods. Eight of the nine farmers responded to ETMDQ, patch tested at 1% in petrolatum (Nishioka et aL, Contact Dermatitis 1996, 35, 241).
Semiconductor compounds and testicular injury in hamsters Gallium arsenide, administered directly into the trachea of hamsters at doses of 7.7 mg/kg body weight (twice weekly for 8 wk), produced testicular toxicity of a kind previously reported in rats. Indium arsenide (previously reported to be a weak testicular toxicant in rats) and arsenic trioxide had no effect on the testes of hamsters (Omura et =l., Toxicology Letters 1996, 89, 123).
Fatty alcohols contact dermatitis The frequency of sensitization to fatty alcohols has been estimated in Italian patients with suspected cosmetic or medicament contact dermatitis. Patch tests (48-hr covered contact) using oleyl 00% in petrolatum), myristyl (5%), stearyl 00%), cetyl 00%) and lauryl (5%) alcohols were conducted in
Contact dermatitis from dental disinfectant wipes
Contact allergy to modified rosins A group of Swedish and Portugese dermatologists have presented evidence which highlights that contact allergy to chemically-modified rosin (colophony) may be missed if patch testing is performed with only unmodified rosin. In a series of patch tests conducted at dermatology clinics throughout Europe some of the patients giving positive allergic reactions to the modified rosin components maleopimaric acid and glyceryl 1-monoabietate, gave no reaction to unmodified rosin. The investigators recommended additional patch testing with a number of modified rosins when patients suspected of rosin allergy fail to react to the unmodified product (G~Cvertet aL, Contact Dermatitis 1996, 35, 290).
Information Section
100 ppm N,N-dimethylethanolamine, a concentration which was overtly maternally toxic. No effects on the offspring were seen at 30 ppm, although maternal toxicity persisted at 10 ppm, the lowest concentration tested (Leung et al., ]ournal of Applied Toxicology 1996, 16, 533).
146 patients (aged 13-72 yr) over a 3-yr period. Positive allergic reactions were observed in 34 (23.2%) patients, 33 showing sensitivity to oleyl alcohol Three patients reacted to the myristyl, and two to the stearyl alcohol (Tosti et aL, Contact Dermatitis 1996, 35, 287).
Occupational dermatitis from hydralazine and bendroflumethiazide
Allergy to disodium ricinoleamido MEA-sulfosuccinate
Propranolol, hydralazine and bendroflumethiazide were found to cause occupational eczema on the hands, forearms and armpits in a 54-yr-old Portuguese worker employed for the last 9 yr in drug synthesis. New products had been introduced 9 months before onset of symptoms. Patch tests with propranolol, hydralazine (both at 0.1% in petrolatum), and bendroflumethiazide (2.0% in petrolatum) gave positive reactions. Although previous cases of occupational contact dermatitis from propranolol have been reported, the investigators claimed this to be the first from hydralazine and bendroflumethiazide (Pereira et a£, Contact Dermatitis 1996, 35, 303).
A 38-yr-old UK patient who developed dermatitis of the head and neck, starting "a few hours after~ using a new shampoo, reacted positively in patch tests to 0.01% disodium ricinoleamido MEAsulfosuccinate, an anionic surfactant found in various hairdressing products, and in the new shampoo at 0.8%. Although there have been several reports of allergic reactions from cocamidopropyl betaine (a similarly used surfactant), the investigators suggest that this might be the first from disodium ricinoleamido MEA-sulfosuccinate ~Tan et al., Contact Dermatitis 1996, 35, 307).
Contact dermatitis due to ETMDQ
Hand dermatitis to N-benzyl-N,N-dihydroxyethyl-N-cocosalkyl-ammonium chloride (a quaternary ammonium compound present in disinfectant wipes used in dentistry) has been reported in a 25-yr-old Italian woman. She had suffered the problem for the last year of her 3-yr career as a dental nurse. Patch tests with a 0.01% aqueous sohtion confirmed her allergy. The investigators were "not aware of other cases of contact sensitization reported to this compound~ (Placucci et al., Contact Dermatitis 1996, 35, 306).
What is claimed to be the first report of sensitization to 6-ethoxy-2,2,4-trimethyl-l,2dihydroquinoline (a rubber antioxidant) describes leg and foot dermatitis in Japanese rice farmers who wear rubber boots for long periods. Eight of the nine farmers responded to ETMDQ, patch tested at 1% in petrolatum (Nishioka et aL, Contact Dermatitis 1996, 35, 241).
Semiconductor compounds and testicular injury in hamsters Gallium arsenide, administered directly into the trachea of hamsters at doses of 7.7 mg/kg body weight (twice weekly for 8 wk), produced testicular toxicity of a kind previously reported in rats. Indium arsenide (previously reported to be a weak testicular toxicant in rats) and arsenic trioxide had no effect on the testes of hamsters (Omura et =l., Toxicology Letters 1996, 89, 123).
Fatty alcohols contact dermatitis The frequency of sensitization to fatty alcohols has been estimated in Italian patients with suspected cosmetic or medicament contact dermatitis. Patch tests (48-hr covered contact) using oleyl 00% in petrolatum), myristyl (5%), stearyl 00%), cetyl 00%) and lauryl (5%) alcohols were conducted in
Contact dermatitis from dental disinfectant wipes
Contact allergy to modified rosins A group of Swedish and Portugese dermatologists have presented evidence which highlights that contact allergy to chemically-modified rosin (colophony) may be missed if patch testing is performed with only unmodified rosin. In a series of patch tests conducted at dermatology clinics throughout Europe some of the patients giving positive allergic reactions to the modified rosin components maleopimaric acid and glyceryl 1-monoabietate, gave no reaction to unmodified rosin. The investigators recommended additional patch testing with a number of modified rosins when patients suspected of rosin allergy fail to react to the unmodified product (G~Cvertet aL, Contact Dermatitis 1996, 35, 290).