Available online at www.sciencedirect.com
ScienceDirect Volume 14, November 2016
CONTENTS Abstracted/indexed in: EMBASE. Also covered in the abstract and citation database Scopus®. Full text available on ScienceDirect ®
Editorial overviews iv
Eleftherios Terry Papoutsakis and Nigel Titchener-Hooker Editorial overview: Biotechnology and bioprocess engineering
110
Mahmoud El-Halwagi and Ka M Ng Editorial overview: Process systems engineering
1
Paul R Amyotte, Scott Berger, David W Edwards, Jai P Gupta, Dennis C Hendershot, Faisal I Khan, M Sam Mannan and Ronald J Willey Why major accidents are still occurring
9
Faisal Khan, Seyed Javad Hashemi, Nicola Paltrinieri, Paul Amyotte, Valerio Cozzani and Genserik Reniers Dynamic risk management: a contemporary approach to process safety management
Cong T Trinh and Brian Mendoza Modular cell design for rapid, efficient strain engineering toward industrialization of biology
26
Song Wang, Jian Zhang, Sujing Wang and Qiang Xu Dynamic simulation for flare minimization in chemical process industry under abnormal operations
Thekla Cordes and Christian M Metallo Tracing insights into human metabolism using chemical engineering approaches
35
Fadwa Eljack and Monzure-Khoda Kazi Process safety and abnormal situation management
Biotechnology and bioprocess engineering Edited by Eleftherios Terry Papoutsakis and Nigel J Titchener-Hooker 18
72
Process systems engineering Edited by Mahmoud El-Halwagi and Ka Ming Ng
82
Wen Kang Chou and Mark P Brynildsen A biochemical engineering view of the quest for immunepotentiating anti-infectives
42
Nitin Roy, Fadwa Eljack, Arturo Jiménez-Gutiérrez, Bin Zhang, Preetha Thiruvenkataswamy, Mahmoud El-Halwagi and M Sam Mannan A review of safety indices for process design
93
Shuai Qian and Patrick C Cirino Using metabolite-responsive gene regulators to improve microbial biosynthesis
49
Yiyang Dai, Hangzhou Wang, Faisal Khan and Jinsong Zhao Abnormal situation management for smart chemical process operation
103
Xuefeng “Nick” Peng, Sean P Gilmore and Michelle A O’Malley Microbial communities for bioprocessing: lessons learned from nature
56
Azmi Mohd Shariff, Hanida Abdul Aziz and Noor Diana Abdul Majid Way forward in Process Safety Management (PSM) for effective implementation in process industries
112
Patricia Roch and Carl-Fredrik Mandenius On-line monitoring of downstream bioprocesses
61
121
Jonathan M Burg, Charles B Cooper, Zhixia Ye, Benjamin R Reed, Eirik A Moreb and Michael D Lynch Large-scale bioprocess competitiveness: the potential of dynamic metabolic control in two-stage fermentations
Faisal Khan, Premkumar Thodi, Syed Imtiaz and Rouzbeh Abbassi Real-time monitoring and management of offshore process system integrity
137
Mimi H Hassim Comparison of methods for assessing occupational health hazards in chemical process development and design phases
150
Andrea CME Rayat, Alex Chatel, Mike Hoare and Gary J Lye Ultra scale-down approaches to enhance the creation of bioprocesses at scale: impacts of process shear stress and early recovery stages
DOI 10.1016/S2211-3398(16)30102-2
The cover Methane transport through a carbon nanotube