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Contents of volume 29
1SSN 0306-3623/97 $17.00 + .00 PII S0306-3623(97)000374-1 All rights reserved
Gen. Pharmac. Vol. 29, No. 5, pp. III-IX, 1997 Copyright © 1997 Elsevier Science Inc. Printed in the USA. ELSEVIER
Contents of Volume 29 Vol. 29 No. 1 Introduction R. J. Walker
1
Scientific Career and Main Scientific Achievements of Professor Katalin S.-R6zsa, Dr. Sci.
Reviews G. Kemenes
In vivo neuropharmacological and in vitro laser ablation techniques as tools in the analysis of neuronal circuits underlying behavior in a molluscan model system
K. Richter and G.-A. B6hm
17
The molting gland of the cockroach Periplanetaamericana: secretory activity and its regulation
T. A. Miller
23
Control of circulation in insects
D. Sonetti, E. Ottaviani and G. B. Stefano
39
Opiate signaling regulates microglia activities in the invertebrate nervous system
G. A. Buznikov, L. N. Koikov, Yu. B. Shmukler and M. J. Whitaker
49
Nicotinic antagonists (piperidines and quinuclidines) reduce the susceptibility of early sea urchin embryos to agents evoking calcium shock
G. L~ing, O. Kufc~k, T. Szegletes and J. Nemcs6k
55
Quantitative distributions of different cholinesterases and inhibition of acetylcholinesterase by metidathion and paraquat in alimentary canal of common carp
R. B. Hill
61
Neurohumoral control of ionic pumping in molluscan muscle: III. cholinergic control of the response to low potassium levels
K. V. Azatian, S. N. Ayrapetyan and D. O. Carpenter
67
Metabotropic GABA receptors regulate acetylcholine responses on snail neurons
K. S.-R6zsa, S. S. Rubakhin, A. Sziics, T. K. Hughes and G. B. Stefano
73
Opposite effects of interleukin-2 and interleukin-4 on GABA-induced inward currents of dialysed Lymnaea neurons
J. Nemcs6k, L. Hiripi, M. Patocskai, J. Sal~nki and O. Kufcs~ik
79
The effects of pesticides on monoaminergic system related to periodic activity of mussels (Anodonta cygnea L.)
E. I. Solntseva, J. V. Bukanova, R. U. Ostrovskaya, T. A. Gudasheva, T. A. Voronina and V. G. Skrebitsky
85
The effects of piracetam and its novel peptide analogue GVS-111 on neuronal voltage-gated calcium and potassium channels
R. P. CroU, M. W. Baker, M. Khabarova, E. E. Voronezhskaya and D. A. Sakharov
91
Serotonin depletion after prolonged chlorpromazine treatment in a simpler model system
T. Kiss and O. N. Osipenko
97
Effectof molluscan neuropeptide RAPYFVamide on identified Helix pomatia L. neurons
Original Papers
M. Ohtani, Y. Muneoka, O. Matsushima, T. Takao, Y. Shimonishi, A. R. White, S. Pedder, R. Sharma, M. A. Lennon, S. Katugampola and R. J. Walker
103
Isolation of bioactive compounds from Helix aspersanerve tissue and the effect of pQPPLPRYamide on heart, esophagus and central neurons of H. aspersa and rectum of Anodonta wood/ana
Vol. 29 No. 2 Rev/eoos P. S. Widdowson, M. G. Simpson and I. Wyatt
113
t-2-Chlorpropionic acid-induced neurotoxicity in the rat: a valuable model for studying selective neuronal cell death/n vivo
III
Contents K. C. Ong and H-E. Khoo
121
Biological effects of myricetin
J. Bondeson
127
The mechanisms of action of disease-modifying antitheumatic drugs: a review with emphasis on macrophage signal transduction and the induction of proinflammatory cytokines
C. Thomsen
151
The L-AP4 receptor
C. Thiemermann
159
Nitric oxide and septic shock
H. Parekh and Henry Simpkins
167
The transport and binding of taxol
A. Fern,~ndez-L6pez, M. A. Chinchetru and P. Calvo Fern~dez
173
The automdiographic perspective of central benzodiazepine receptors: a short review
C. Windmeier and A. M. Gressner
181
Pharmacological aspects of pentoxifylline with emphasis on its inhibitory actions on hepatic fibrogenesis
T. Utkan, T. Kaya and Y. Sarioglu
197
Effects of sympathectomy on endothelin-1 and histamine responses of rabbit carotid artery
F. IL Neto, O. Mesquita Jtlnior and G. B. Olivera
201
Antiarrhythmic and electrophysiological effects of the novel KaTe channel opener, rilmakalim, in rabbit cardiac cells
C. F. Polo, A. M. Buzahh, E. S. Vazquez, S. Go Afonso, N. M. Navone and A. M. del Carmen Batlh
207
Griseofulvin-induced hepatopathy due to abnormalities in heme pathway
C. Camello, A. I. Lajas, A. Gonzalez, P. J. Camello and J. A. Pariente
211
Histamine does not potentiate cyclic AMP-mediated amylase secretion in the guinea-pig pancreatic acinar cells
C. Pozzoli, E. Poll, A. Costa and F. De Ponti
217
Absence of histamine H3-receptors in the rabbit colon: species difference
S. Kumar and H. N. Bhargava
223
Time course of the changes in central nitric oxide synthase activity following chronic treatment with morphine in the mouse: reversal by naltrexone
T. Yatsu, W. Uchida, O. lnagaki, A. Tanaka and T. Takenaka
229
Dopamine DA~ receptor agonist activity in YM435 in the canine renal vasculature
C. Ivancheva, N. Pencheva and R. Radomirov
233
Pattern of nonadrenergic, noncholinergic responses during short- or long-lasting electrical stimulation in guinea-pig ileum
M. M. Winnicka and J. J. Braszko
239
6-OHDA lesions to the central amygdala abolish angiotensins facilitation of object recognition in rats
A. Alfleri and C. Gardner
245
The NKI antagonist GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder
B. H. Shah, B. Safdar, S. S. Virani, A. Nawaz, S. A. Saeed and A. H. Gilani
251
The antiplatelet aggregatory activity of Acac/a n//ot/ca is due to blockade of calcium influx through membrane calcium channels
C. R. da Silva and L. M. Bendhack
257
Thapsigargin does not affect phenylephrine-induced contractions in the anococcygeus muscle of rats
H. Z. Giiney, C. Z. G6rgiin, U. Hodo~lugil and H. Zengil
261
Effectsof auro-detoxin treatment on vascular responses in mouse aorta
R. DeLucia, C. S. Phneta, M. L. Aizenstein and C. Scavone
265
Repeated administration intensifies the reinforcing effect of fencamfamine in rats
T. B. Ng and W. Y. Chan
269
Polysaccharopeptide from the mushroom Cor~/us versmo/orpossesses analgesic activity but does not produce adverse effects on female reproductive or embryonic development in mice
C. Pankucsi, T. B~tny/asz,J. Magyar, I. Gy6n6s, A. Kov~cs, G. Sz6n.~si, A. Vart6 and P. P. N~ln,~si
275
Electrophysiological effects of EGIS-7229, a new antiarthythmic agent, in isolated guinea pig papillary muscle
Genera/Papers
IV
Contents J. L. Martlnez and M. Penna
281
Influences of changes in calcium concentration, cocaine and clonidine on the cardiac effect of acetaldehyde in rat isolated atria
M. R. Zarrindast and A. A. Moghadamnia
285
Adenosine receptor agents and conditioned place preference
Book Rev/ews
291
Vol. 29 No. 3 Rev/etes P. J. Pauwels
293
5-HTI~a receptor antagonists
D. M. Zisterer and D. C. Williams
305
Peripheral-type benzodiazepine receptors
G. P. Biewenga, G. 1L M. M. Haenen and Ao Bast
315
The pharmacology of the antioxidant lipoic acid
K. Tuovinen, E. Kaliste-Korhonen and O. I-l~ninen
333
Gender differences in activities of mouse esterase and sensitivities to DFP and sarin toxicity
K. Yamanaga, H. Shinyama, T. Akira, M. lwamoto, T. Uchida, N. Nakamura and Y. Kagitani
337
AE0047-mediated calcium channel blocking in vascular smooth muscles
M. Satoh, K. Matsuo, H. Kiriya, T. Mashino, M. Hirobe and I. Takayanagi
345
Inhibitory effect of a fullerene derivative, monomalonic acid C~ on nitric oxide-dependent relaxation of aortic smooth muscle
C. Ito, R. Kawamura, Y. lsobe, K. Tsuchida, M. Muramatsu and S. Higuchi
353
Effect of a novel 5-hydroxytryptamine3 (5-HT0 receptor antagonist, GK-128, on 5-HT3 receptors mediating contractions and relaxations in guinea-pig distal colon
K. Noguchi, K. Takahashi, H. Araki and S. Higuchi
361
Vasodilation profile of CD-832, a novel dihydropyridine derivative in rabbit aorta
B. L. Slomiany, J. Piotrowski and A. Slomiany
367
Cell cycle progression during gastric ulcer healing by ebrotidine and sucralfate
M. T. Matuszek and I. T. Gagalo
371
The antipyretic activity of adenosine agonists
T. Nasu and T. Iwai
375
Changes of response to caffeine in Ca2+-deficient medium in guinea-pig tenia coli
S. Karasaki, R. Sato and R. Katori
379
The blocking mechanism of sodium currents by a new class I antiarrhythmic drug, Ro 22-9194, in isolated guinea-pig ventricular myocytes
I. J. Chen, Y. C. Lo, W. J. Lo, J. L. Yeh and B. N. Wu
387
Capsazocaine: a capsaicin-sensitive functional antagonist displays an argument on sensory capsaicin receptor
H. N. Bhargava and S. Kumar
397
Effect of multiple injections of U-50,488H, a K-opioid receptor agonist, on the activity of nitric oxide synthase in brain regions and spinal cord of mice
M. Minami, S.-i. Kimura, T. Endo, N. Hamaue, M. Hirafuji, Y. Monma, H. Togashi, M. Yoshioka, H. Saito, S. Watanabe, T. Kobayashi and H. Okuyama
401
Effects of dietary docosahexaienoic acid on survival time and stroke-related behavior in stroke-prone spontaneously hypertensive rats
M. del Mar Giadis-ViUanueva, F. Usera and M. J. Toro
409
Denervation-induced supersensitivity to forskolin and pinacidil is not related to changes in the adenylate cyclase transduction pathway in the rabbit femoral artery
R. Gaggi, R. Dall'Olio, M. Santangelo and P. Roncada
415
Actions of nimodipine on the serotonergic systems of rat brain
C. D. Lewis and S. M. O. Hourani
421
Involvement of functional antagonism in the effects of adenosine antagonists and L-NAME in the rat isolated heart
J. c . Hancox
429
Amiodarone blocks L-type calcium current in single myocytes isolated from the rabbit atrioventricular node
Genera/Papers
V
Contents P. J. Rice, S. T. Abraham, N.-Y. Huang and R. J. Doman
437
Extraneuronal uptake inhibitor U-0521 decreases contractile responses in rat vas deferens
K. Kramer, C. G. W. C. Smink and A. Bast
441
Effect of phospholipase A2 activation on the receptor function in the rat left atrium: unmasking of a positive inotropic effect of methacholine
M. AbdoUahi, A.-R. Dehpour and H. Rashidi
447
Inhibition by lithium of gentamicin-induced release of N-acetyl13-1>glucosaminidase in rat submandibular saliva
M. Ukai, J. Monma, N. Shinkai, Y. Sasaki and T. Kameyama
453
Effects of Tyr-o-Arg-Phe-13-Ala-NH2, a novel dermorphin analog, on elevated plus-maze learning and spontaneous alternation performance in mice
X. Garcla, L. Cartas.Heredia, M. Lorenzana.Jimenez and E. Gij6n
457
Vasoconstrictor effect of Cissus sicyoides on guinea-pig aortic rings
F. S. Abulaban, M. A. H. Dhariwal, A. M. AI.Bekairi and M. Raza
463
Antinociceptive activity of sodium valproate in mice after chronic treatment
M. Samini, A. R. Dehpour and S. Yousefnejad
469
The effects of dopaminergic and adrenergic drags on twitch response of guinea-pig common bile duct
T. Tominaga, A. Watanabe, J.-i. Tsuji, A. Koda, H. Nagai, Y. Kumazawa and H. Shimada
473
The effects of TYB-2285 and its metabolites on lymphocyte responses in vitro
M. Bernardi, R. Deslauriers, J. Docherty, C. Rossi, L. Rossini, P. Rossini and C. Tonnini
477
Spectral analysis of intercycle heart fluctuations in Xenopus laevis, conscious or spinalized, treated with calcium channel blockers. Part I
R. S. Mathias, J. C. C. Carvalho, M. T. Cavalcante and S. de Moraes
483
Effects of simulated myocardial ischemic conditions on the responses of isolated human umbilical artery strips to 5-hydroxytryptamine and prostaglandin Fz~
J. M. de Gandarias, J. lrazusta, D. Fern~indez, A. Varona, J. Gil and L. Casis
489
Effect of lidocaine administration on the enkephalin-degrading aminopeptidase activities in discrete areas of the rat brain
Book Reviews
495
Vol. 29 No. 4 Reviews M. Witvrouw and E. De Clercq
497
Sulfated polysaccharides extracted from sea algae as potential antiviral drugs
O. Cantoni and P. Giacomoni
513
The role of DNA damage in the cytotoxic response to hydrogen peroxide/histidine
S. Giir
517
Effects of adenosine and isoprenaline in left atria from both neonatal and middle-aged noninsulin-dependent diabetic rat models
X. Y. Han, T. L. Salunga, W. Zhang, H. Takeuchi and K.-I. Matsunami
523
Modulation by APGW-amide, an Achatina endogenous inhibitory tetrapeptide, of currents induced by neuroactive compounds on Achatina neurons: amines and amino acids
X. Y. Han, T. L. Salunga, W. Zhang, H. Takeuchi and K.-I. Matsunami
531
Modulation by APGW-amide, an Achat/na endogenous inhibitory tetrapeptide, of currents induced by neuroactive compounds on Achat/na neurons: peptides
B. Fernandez del Pozo, F. P6rez-Vizcaino, C. Fern~tndez, F. Zaragoz~ and J. Tamargo
539
Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle
K. Shibasaki, ¥. Arai, W. Uchida, T. Okazaki, M. Asano and T. Takenaka
545
Antianginal effects of YM430, a novel calcium entry-blocking and ~-adrenoceptor-blocking agent in several experimental angina models
J. A. A. De Souza, H. R. De Oliveria, C. K. Miyasaka, F. Gacek, R. P. Torres, J. Mancini Filho and R. Curi
551
Changes in the activities of antioxidant enzymes of the lymphoid organs of 21-day pregnant rats due to administration of fish oil by gavage
General Papers
VI
Contents I. Hisatome, Y. Tanaka, N. Sasaki, K. Hiroe, G. U. Ahmmed, M. Tsuboi, I. Manabe, T. Suga, Y. Yamamoto, A. Ohtahara, T. Kinugawa K. Ogino, O. Igawa, A. Yoshida, M. Saito, R. Sato and C. Shigemasa
557
Influence of extracellular H + and Ca 2+ on Ro 22-9194-induced block of sodium current in cardiac myocytes
C. Karasu, G. Ozansoy, O. Bozkurt, D. Erdo~an and S. Omero~lu
561
Changes in isoprenaline-induced endothelium-dependent and -independent relaxations of aorta in long-term STZ-diabetic rats: reversal effect of dietary vitamin E
E. Gerez, E. Vazquez, F. Caballero, C. Polo and A. Batlle
569
Altered heme pathway regulation and drug metabolizing enzyme system in a mouse model of hepatocarcinogenesis: effect of veronal
H. Ueda
575
Multiple forms of AMPA-type glutamate receptor mRNA phenotypes in goldfish retina and tectum
S. Nikfar, M. Abdollahi, F. Etemad and M. Sharifzadeh
583
Effects of sweetening agents on morphine-induced analgesia in mice by formalin test
A. Saghyan, A. Hunanian and S. Ayrapetyan
587
Effect of locust poison on neuromembrane functional activity
H. Tsunobuchi-Ushijima and Y. Gomi
591
Effects of phorbol-12,13-dibutyrate and protein kinase C inhibitors on Mn>-dependent norepinephrine-induced contractions involving increase in Mn 2+ sensitivity in Ca2+-depleted vas deferens of the guinea pig
J. A. King, H. Huddart and W. G. Staff
597
Purinergic modulation of rat urinary bladder detrusor smooth muscle
V. Villagrasa, L. Berto, J. Cortijo, M. Perpina, C. Sanz and E. J. Morcillo
605
Effects of erythromycin on chemoattractant-activated human polymorphonuclear leukocytes
A. Labadla, G. Costa, E. Jimenez, D. Triguero and A. Garcla-Pascual
611
Endothelin receptor-mediated Ca 2+ mobilization and contraction in bovine oviductal arteries: comparison with noradrenaline and potassium
Y. Abu-Ghalyun, A. Masalmeh and S. AI-Khalil
621
Effects of allocryptopine, an alkaloid isolated from Glaucium arabicum on rat isolated ileum and urinary bladder
W. Zhang, H. Takeuchi, M. Kurono and M. Emaduddin
625
Ouabain-sensitive K+-dependent outward current caused by threo-[B-hydroxy-L-glutamic acid on snail neuron
T. Yoshimura, C. Kurita, T. Nagao, E. Usami, T. Nakao, S. Watanabe, J. Kobayashi, F. Yamazaki, H. Tanaka and H. Nagai
633
Effects of cAMP-phosphodiesterase isozyme inhibitor on cytokine production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells
A. A. Almotrefi, M. C. Basco, A. Moorji and N. Dzimiri
639
Effects of amiodarone on ouabain binding to microsomal Na +, K+-ATPase in guinea-pig heart preparations
Y. Maruoka, Y. Ohno, H. Tanaka, H. Yasuda, K.-I. Ohtani, H. Sakamoto, A. Kawabe, C. Tamamura and M. Nakamura
645
Selective depression of the spinal polysynaptic reflex by the NMDA eceptor antagonists in an isolated spinal cord in vitro
J. P. De La Cruz, M. M6rida, J. A. Gonzlilez-Correa, P. Ortiz and F. Sfinchez de la Cuesta
651
Effects of S-adenosyl-L-methionine on blood platelet activation
M.W. Fryer and W. E. Glover
657
Effects of 4-methyl-2-aminopyridine on [3H]-noradrenaline overflow and contractility of isolated rabbit arteries
A. M. Silvlin, M. J. Abad, P. Bermejo and A. M. Villar
665
Adjuvant-carrageenan-induced inflammation in mice
H. Kr6ger, R. Miesel, A. Dietrich, M. Ohde, S. Altrichter, C. Braun and H. Ockenfels
671
Suppression of type II collagen-induced arthritis by N-acetyl-L cysteine in mice
M. Abdollahi, A.-R. Dehpour and M. Fooladgar
675
Alteration of rat submandibulary gland secretion of protein, calcium and N-acetyl-lB-D-glucosaminidase activity by lead
S. I. Chandranath
681
In vitro administration of 1713-estradiol inhibits drug-induced contractions
of the rat isolated seminal vesicle
VII
Contents K. A. Raheem, N. Ismael, A. Saad and S. EI-Sayad
687
Gluconeogenic activity in response to chronic administration of amphetamine sulphate and drug withdrawal
Vol. 29 No. 5 Rev/ews M. E. Pueyo and J.-B. Michel
691
Angiotensin 11 receptors in endothelial cells
M. Holstad, L. Jansson and S. Sandier
697
Inhibition of nitric oxide formation by aminoguanidine: an attempt to prevent insolin-dependent diabetes meUitus
G. Nocentini and A. Barzi
701
Antitumor acitvity of 2,2'-bipyridyl-6-carbothioamide: a ribonucleotide reductase inhibitor
P. I. B. Ceron and L. M. Bendhack
707
Increased contractile response induced with ouabain is abolished by thapsigargin in aorta of renal hypertensive rats
H. Nishiwaki, S. Kato and K. Takeuchi
713
Irritant action of monochloramine in rat stomachs: effects of zinc L-carnosine (polaprezinc)
R. Rodrigo and L. Thielemann
719
Effects of chronic and acute ethanol exposure on renal (Na+K)-ATPase in the rat
M. G. Vecchia, M. C. Filho, C. R. C. Fellipe, R. Curi and E. A. Newsholme
725
Acetate and propionate potentiate the antiproliferative effect of butyrate on RBL-2H3 growth
Y.-S. Lau, Y. K. Fung and T. M. Anderson
729
Antagonistic effects of isofloxythepin on dopamine D~ and Dz receptors and behaviors in rats
C. Pou, E. K. N6non6n~, T. A. Reader and A. Fargin
737
The human 5-HT1A receptor: comparison of its binding properties in transfected cells and cortical tissue
P. J. Pauwels
749
Competitive and silent antagonism of recombinant 5-HT~B receptors by amiloride
M. Mita, K. Satoh-Akimoto, K. Oishi, T. Hashimoto and M. K. Uchida
753
Inhibition of muscarinic receptor-operated Ca z+ sensitization by short-term desensitization of c~-toxin-permeabilized smooth muscle cells from guinea pig stomach
H. Honda, Y. Ikarashi, S. Yonebayashi and K. Shimizu
763
A difference in responsiveness of isolated hepatic artery, aorta, portal vein and vena cava of pig to flavin adenine dinucleotide including liver extract
K.-I. Kohno, M. Niwa, M. Nozaki, T. Uematsu and H. Fujimura
767
Role of nitric oxide in the convulsive seizures induced by fluoroquinolones coadministered with 4-biphenyl acetic acid
K. Hamada, Y. Sasaki, N. Taniguchi, H. Fukui, Y. Miyatsuka, Y. Kimura, Y. Ukai, Y. Yoshikuni and K. Kimura
771
Anticholinergic and calcium antagonistic activities of NS-21 contribute to the inhibition of rat urinary bladder contractions
G. Csaba and A. Inczefi-Gonda
779
Effect of combined neonatal imprinting by vitamin A, vitamin D3, benzypyrene and allylestrenol on adult rat thymus glucocorticoid and uterine estrogen receptors
S. De Moraes, M. T. Cavalcante, J. C. C. Carvalho and R. S. Mathias
783
Endogenous thromboxane A2 does not contribute to the contractile response of human umbilical artery strips to 5-hydroxytryptamine
~. G6k, S. 131ker, A. Hiiseyinov and A. Evin~2
789
Effect of lipoxygenase inhibitor on digoxin-induced cardiac arrhythmias in the isolated perfuesed guinea-pig heart
E. Ettemadzadeh and K. W. O. ~kkerman
793
Effect of morphine on rotational behavior of unilaterally brain-lesioned mice and rats: morphine withdrawal and development of tolerance
M. Nishimura, N. Asai, Y. Taquahashi, E. Satoh and Y. Shimziu
799
Effects of feeding conditions on sensitivity to tubocurarine of nerve-muscle preparations from the mouse
General Papers
VIII
Contents N. Nishimura, M. Matsushita, Y. Taquahashi, Y. Shimizu, E. Satoh and T. Hasegawa
805
Twitch potentiation induced by caffeine in the mouse diaphragm depends on external calcium ions in the absence of potassium ions
M. Nishimura, S. Nakamura, Y. Taquahashi, E. Satoh and Y. Shimizu
809
Effects of feeding condition after birth on the sensitivity of neuromuscular transmission of d-tubocurarine in vitro in mice
Y. Mutsukado, H. Tsuru, M. Sasa, M. Kambe and M. Yamakido
815
Nonadrenergic, noncholinergic inhibitory innervation in the longitudinal muscle of the rabbit portal vein
G. K. Matheson, A. Knowles, D. Guthrie, D. Gage, D. Weinzapfel and J. Blackbourne
823
Actions of serotonergic agents on hypothalamic-pituitary-adrenal axis activity in the rat
S. J. Hughes and M. Hollingsworth
829
Relaxin as a relaxant of the isoalted rat uterus: comparison with its mechanism of action in vivo
A. N. Goku~ra§ and E. F. Tezcan
835
Amitriptyline: a potent inhibitor of butyrylcholinestemsefrom human serum
A. Do~rul, O. Ye§ilyurt, G. Deniz and A. I§imer
839
Analgesic effects of amlodipine and its interaction with morphine and ketorolac-induced analgesia
M. P. Revuelta, B. Cantabrana and A. Hidalgo
847
Depolarization-dependent effect of flavonoids in rat uterine smooth muscle contraction elicited by CaCIz
K. W. Chiu and A. Y. L. Fung
859
The cardiovascular effects of green beans (Phaseolus aureus), common rue (Rum graveolens), and kelp (Laminaria japonica) in rats
M. Koutsoviti-Papadopoulou, G. Kounenis, G. Batzias and V. Elezoglou
863
Effect of cisapride on the isolated guinea pig gall bladder and common bile duct
G. M. Lew
869
Changes in microtubular tau protein after morphine in a cultured human neuroblastoma cell line
H..W. Suh, D.-K. Song and Y.-H. Kim
873
Effects of ginsenosides injected intrathecally or intracerebroventricularly on antinociception induced by morphine administered intracerebroventricularly in the mouse
Volume Contents Author Index Keyword Index
lII X XII
IX
Gen. Pharmac. Vol. 29, No. 5, pp. III-IX, 1997 Copyright © 1997 Elsevier Science Inc. Printed in the USA. ELSEVIER
Contents of Volume 29 Vol. 29 No. 1 Introduction R. J. Walker
1
Scientific Career and Main Scientific Achievements of Professor Katalin S.-R6zsa, Dr. Sci.
Reviews G. Kemenes
In vivo neuropharmacological and in vitro laser ablation techniques as tools in the analysis of neuronal circuits underlying behavior in a molluscan model system
K. Richter and G.-A. B6hm
17
The molting gland of the cockroach Periplanetaamericana: secretory activity and its regulation
T. A. Miller
23
Control of circulation in insects
D. Sonetti, E. Ottaviani and G. B. Stefano
39
Opiate signaling regulates microglia activities in the invertebrate nervous system
G. A. Buznikov, L. N. Koikov, Yu. B. Shmukler and M. J. Whitaker
49
Nicotinic antagonists (piperidines and quinuclidines) reduce the susceptibility of early sea urchin embryos to agents evoking calcium shock
G. L~ing, O. Kufc~k, T. Szegletes and J. Nemcs6k
55
Quantitative distributions of different cholinesterases and inhibition of acetylcholinesterase by metidathion and paraquat in alimentary canal of common carp
R. B. Hill
61
Neurohumoral control of ionic pumping in molluscan muscle: III. cholinergic control of the response to low potassium levels
K. V. Azatian, S. N. Ayrapetyan and D. O. Carpenter
67
Metabotropic GABA receptors regulate acetylcholine responses on snail neurons
K. S.-R6zsa, S. S. Rubakhin, A. Sziics, T. K. Hughes and G. B. Stefano
73
Opposite effects of interleukin-2 and interleukin-4 on GABA-induced inward currents of dialysed Lymnaea neurons
J. Nemcs6k, L. Hiripi, M. Patocskai, J. Sal~nki and O. Kufcs~ik
79
The effects of pesticides on monoaminergic system related to periodic activity of mussels (Anodonta cygnea L.)
E. I. Solntseva, J. V. Bukanova, R. U. Ostrovskaya, T. A. Gudasheva, T. A. Voronina and V. G. Skrebitsky
85
The effects of piracetam and its novel peptide analogue GVS-111 on neuronal voltage-gated calcium and potassium channels
R. P. CroU, M. W. Baker, M. Khabarova, E. E. Voronezhskaya and D. A. Sakharov
91
Serotonin depletion after prolonged chlorpromazine treatment in a simpler model system
T. Kiss and O. N. Osipenko
97
Effectof molluscan neuropeptide RAPYFVamide on identified Helix pomatia L. neurons
Original Papers
M. Ohtani, Y. Muneoka, O. Matsushima, T. Takao, Y. Shimonishi, A. R. White, S. Pedder, R. Sharma, M. A. Lennon, S. Katugampola and R. J. Walker
103
Isolation of bioactive compounds from Helix aspersanerve tissue and the effect of pQPPLPRYamide on heart, esophagus and central neurons of H. aspersa and rectum of Anodonta wood/ana
Vol. 29 No. 2 Rev/eoos P. S. Widdowson, M. G. Simpson and I. Wyatt
113
t-2-Chlorpropionic acid-induced neurotoxicity in the rat: a valuable model for studying selective neuronal cell death/n vivo
III
Contents K. C. Ong and H-E. Khoo
121
Biological effects of myricetin
J. Bondeson
127
The mechanisms of action of disease-modifying antitheumatic drugs: a review with emphasis on macrophage signal transduction and the induction of proinflammatory cytokines
C. Thomsen
151
The L-AP4 receptor
C. Thiemermann
159
Nitric oxide and septic shock
H. Parekh and Henry Simpkins
167
The transport and binding of taxol
A. Fern,~ndez-L6pez, M. A. Chinchetru and P. Calvo Fern~dez
173
The automdiographic perspective of central benzodiazepine receptors: a short review
C. Windmeier and A. M. Gressner
181
Pharmacological aspects of pentoxifylline with emphasis on its inhibitory actions on hepatic fibrogenesis
T. Utkan, T. Kaya and Y. Sarioglu
197
Effects of sympathectomy on endothelin-1 and histamine responses of rabbit carotid artery
F. IL Neto, O. Mesquita Jtlnior and G. B. Olivera
201
Antiarrhythmic and electrophysiological effects of the novel KaTe channel opener, rilmakalim, in rabbit cardiac cells
C. F. Polo, A. M. Buzahh, E. S. Vazquez, S. Go Afonso, N. M. Navone and A. M. del Carmen Batlh
207
Griseofulvin-induced hepatopathy due to abnormalities in heme pathway
C. Camello, A. I. Lajas, A. Gonzalez, P. J. Camello and J. A. Pariente
211
Histamine does not potentiate cyclic AMP-mediated amylase secretion in the guinea-pig pancreatic acinar cells
C. Pozzoli, E. Poll, A. Costa and F. De Ponti
217
Absence of histamine H3-receptors in the rabbit colon: species difference
S. Kumar and H. N. Bhargava
223
Time course of the changes in central nitric oxide synthase activity following chronic treatment with morphine in the mouse: reversal by naltrexone
T. Yatsu, W. Uchida, O. lnagaki, A. Tanaka and T. Takenaka
229
Dopamine DA~ receptor agonist activity in YM435 in the canine renal vasculature
C. Ivancheva, N. Pencheva and R. Radomirov
233
Pattern of nonadrenergic, noncholinergic responses during short- or long-lasting electrical stimulation in guinea-pig ileum
M. M. Winnicka and J. J. Braszko
239
6-OHDA lesions to the central amygdala abolish angiotensins facilitation of object recognition in rats
A. Alfleri and C. Gardner
245
The NKI antagonist GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder
B. H. Shah, B. Safdar, S. S. Virani, A. Nawaz, S. A. Saeed and A. H. Gilani
251
The antiplatelet aggregatory activity of Acac/a n//ot/ca is due to blockade of calcium influx through membrane calcium channels
C. R. da Silva and L. M. Bendhack
257
Thapsigargin does not affect phenylephrine-induced contractions in the anococcygeus muscle of rats
H. Z. Giiney, C. Z. G6rgiin, U. Hodo~lugil and H. Zengil
261
Effectsof auro-detoxin treatment on vascular responses in mouse aorta
R. DeLucia, C. S. Phneta, M. L. Aizenstein and C. Scavone
265
Repeated administration intensifies the reinforcing effect of fencamfamine in rats
T. B. Ng and W. Y. Chan
269
Polysaccharopeptide from the mushroom Cor~/us versmo/orpossesses analgesic activity but does not produce adverse effects on female reproductive or embryonic development in mice
C. Pankucsi, T. B~tny/asz,J. Magyar, I. Gy6n6s, A. Kov~cs, G. Sz6n.~si, A. Vart6 and P. P. N~ln,~si
275
Electrophysiological effects of EGIS-7229, a new antiarthythmic agent, in isolated guinea pig papillary muscle
Genera/Papers
IV
Contents J. L. Martlnez and M. Penna
281
Influences of changes in calcium concentration, cocaine and clonidine on the cardiac effect of acetaldehyde in rat isolated atria
M. R. Zarrindast and A. A. Moghadamnia
285
Adenosine receptor agents and conditioned place preference
Book Rev/ews
291
Vol. 29 No. 3 Rev/etes P. J. Pauwels
293
5-HTI~a receptor antagonists
D. M. Zisterer and D. C. Williams
305
Peripheral-type benzodiazepine receptors
G. P. Biewenga, G. 1L M. M. Haenen and Ao Bast
315
The pharmacology of the antioxidant lipoic acid
K. Tuovinen, E. Kaliste-Korhonen and O. I-l~ninen
333
Gender differences in activities of mouse esterase and sensitivities to DFP and sarin toxicity
K. Yamanaga, H. Shinyama, T. Akira, M. lwamoto, T. Uchida, N. Nakamura and Y. Kagitani
337
AE0047-mediated calcium channel blocking in vascular smooth muscles
M. Satoh, K. Matsuo, H. Kiriya, T. Mashino, M. Hirobe and I. Takayanagi
345
Inhibitory effect of a fullerene derivative, monomalonic acid C~ on nitric oxide-dependent relaxation of aortic smooth muscle
C. Ito, R. Kawamura, Y. lsobe, K. Tsuchida, M. Muramatsu and S. Higuchi
353
Effect of a novel 5-hydroxytryptamine3 (5-HT0 receptor antagonist, GK-128, on 5-HT3 receptors mediating contractions and relaxations in guinea-pig distal colon
K. Noguchi, K. Takahashi, H. Araki and S. Higuchi
361
Vasodilation profile of CD-832, a novel dihydropyridine derivative in rabbit aorta
B. L. Slomiany, J. Piotrowski and A. Slomiany
367
Cell cycle progression during gastric ulcer healing by ebrotidine and sucralfate
M. T. Matuszek and I. T. Gagalo
371
The antipyretic activity of adenosine agonists
T. Nasu and T. Iwai
375
Changes of response to caffeine in Ca2+-deficient medium in guinea-pig tenia coli
S. Karasaki, R. Sato and R. Katori
379
The blocking mechanism of sodium currents by a new class I antiarrhythmic drug, Ro 22-9194, in isolated guinea-pig ventricular myocytes
I. J. Chen, Y. C. Lo, W. J. Lo, J. L. Yeh and B. N. Wu
387
Capsazocaine: a capsaicin-sensitive functional antagonist displays an argument on sensory capsaicin receptor
H. N. Bhargava and S. Kumar
397
Effect of multiple injections of U-50,488H, a K-opioid receptor agonist, on the activity of nitric oxide synthase in brain regions and spinal cord of mice
M. Minami, S.-i. Kimura, T. Endo, N. Hamaue, M. Hirafuji, Y. Monma, H. Togashi, M. Yoshioka, H. Saito, S. Watanabe, T. Kobayashi and H. Okuyama
401
Effects of dietary docosahexaienoic acid on survival time and stroke-related behavior in stroke-prone spontaneously hypertensive rats
M. del Mar Giadis-ViUanueva, F. Usera and M. J. Toro
409
Denervation-induced supersensitivity to forskolin and pinacidil is not related to changes in the adenylate cyclase transduction pathway in the rabbit femoral artery
R. Gaggi, R. Dall'Olio, M. Santangelo and P. Roncada
415
Actions of nimodipine on the serotonergic systems of rat brain
C. D. Lewis and S. M. O. Hourani
421
Involvement of functional antagonism in the effects of adenosine antagonists and L-NAME in the rat isolated heart
J. c . Hancox
429
Amiodarone blocks L-type calcium current in single myocytes isolated from the rabbit atrioventricular node
Genera/Papers
V
Contents P. J. Rice, S. T. Abraham, N.-Y. Huang and R. J. Doman
437
Extraneuronal uptake inhibitor U-0521 decreases contractile responses in rat vas deferens
K. Kramer, C. G. W. C. Smink and A. Bast
441
Effect of phospholipase A2 activation on the receptor function in the rat left atrium: unmasking of a positive inotropic effect of methacholine
M. AbdoUahi, A.-R. Dehpour and H. Rashidi
447
Inhibition by lithium of gentamicin-induced release of N-acetyl13-1>glucosaminidase in rat submandibular saliva
M. Ukai, J. Monma, N. Shinkai, Y. Sasaki and T. Kameyama
453
Effects of Tyr-o-Arg-Phe-13-Ala-NH2, a novel dermorphin analog, on elevated plus-maze learning and spontaneous alternation performance in mice
X. Garcla, L. Cartas.Heredia, M. Lorenzana.Jimenez and E. Gij6n
457
Vasoconstrictor effect of Cissus sicyoides on guinea-pig aortic rings
F. S. Abulaban, M. A. H. Dhariwal, A. M. AI.Bekairi and M. Raza
463
Antinociceptive activity of sodium valproate in mice after chronic treatment
M. Samini, A. R. Dehpour and S. Yousefnejad
469
The effects of dopaminergic and adrenergic drags on twitch response of guinea-pig common bile duct
T. Tominaga, A. Watanabe, J.-i. Tsuji, A. Koda, H. Nagai, Y. Kumazawa and H. Shimada
473
The effects of TYB-2285 and its metabolites on lymphocyte responses in vitro
M. Bernardi, R. Deslauriers, J. Docherty, C. Rossi, L. Rossini, P. Rossini and C. Tonnini
477
Spectral analysis of intercycle heart fluctuations in Xenopus laevis, conscious or spinalized, treated with calcium channel blockers. Part I
R. S. Mathias, J. C. C. Carvalho, M. T. Cavalcante and S. de Moraes
483
Effects of simulated myocardial ischemic conditions on the responses of isolated human umbilical artery strips to 5-hydroxytryptamine and prostaglandin Fz~
J. M. de Gandarias, J. lrazusta, D. Fern~indez, A. Varona, J. Gil and L. Casis
489
Effect of lidocaine administration on the enkephalin-degrading aminopeptidase activities in discrete areas of the rat brain
Book Reviews
495
Vol. 29 No. 4 Reviews M. Witvrouw and E. De Clercq
497
Sulfated polysaccharides extracted from sea algae as potential antiviral drugs
O. Cantoni and P. Giacomoni
513
The role of DNA damage in the cytotoxic response to hydrogen peroxide/histidine
S. Giir
517
Effects of adenosine and isoprenaline in left atria from both neonatal and middle-aged noninsulin-dependent diabetic rat models
X. Y. Han, T. L. Salunga, W. Zhang, H. Takeuchi and K.-I. Matsunami
523
Modulation by APGW-amide, an Achatina endogenous inhibitory tetrapeptide, of currents induced by neuroactive compounds on Achatina neurons: amines and amino acids
X. Y. Han, T. L. Salunga, W. Zhang, H. Takeuchi and K.-I. Matsunami
531
Modulation by APGW-amide, an Achat/na endogenous inhibitory tetrapeptide, of currents induced by neuroactive compounds on Achat/na neurons: peptides
B. Fernandez del Pozo, F. P6rez-Vizcaino, C. Fern~tndez, F. Zaragoz~ and J. Tamargo
539
Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle
K. Shibasaki, ¥. Arai, W. Uchida, T. Okazaki, M. Asano and T. Takenaka
545
Antianginal effects of YM430, a novel calcium entry-blocking and ~-adrenoceptor-blocking agent in several experimental angina models
J. A. A. De Souza, H. R. De Oliveria, C. K. Miyasaka, F. Gacek, R. P. Torres, J. Mancini Filho and R. Curi
551
Changes in the activities of antioxidant enzymes of the lymphoid organs of 21-day pregnant rats due to administration of fish oil by gavage
General Papers
VI
Contents I. Hisatome, Y. Tanaka, N. Sasaki, K. Hiroe, G. U. Ahmmed, M. Tsuboi, I. Manabe, T. Suga, Y. Yamamoto, A. Ohtahara, T. Kinugawa K. Ogino, O. Igawa, A. Yoshida, M. Saito, R. Sato and C. Shigemasa
557
Influence of extracellular H + and Ca 2+ on Ro 22-9194-induced block of sodium current in cardiac myocytes
C. Karasu, G. Ozansoy, O. Bozkurt, D. Erdo~an and S. Omero~lu
561
Changes in isoprenaline-induced endothelium-dependent and -independent relaxations of aorta in long-term STZ-diabetic rats: reversal effect of dietary vitamin E
E. Gerez, E. Vazquez, F. Caballero, C. Polo and A. Batlle
569
Altered heme pathway regulation and drug metabolizing enzyme system in a mouse model of hepatocarcinogenesis: effect of veronal
H. Ueda
575
Multiple forms of AMPA-type glutamate receptor mRNA phenotypes in goldfish retina and tectum
S. Nikfar, M. Abdollahi, F. Etemad and M. Sharifzadeh
583
Effects of sweetening agents on morphine-induced analgesia in mice by formalin test
A. Saghyan, A. Hunanian and S. Ayrapetyan
587
Effect of locust poison on neuromembrane functional activity
H. Tsunobuchi-Ushijima and Y. Gomi
591
Effects of phorbol-12,13-dibutyrate and protein kinase C inhibitors on Mn>-dependent norepinephrine-induced contractions involving increase in Mn 2+ sensitivity in Ca2+-depleted vas deferens of the guinea pig
J. A. King, H. Huddart and W. G. Staff
597
Purinergic modulation of rat urinary bladder detrusor smooth muscle
V. Villagrasa, L. Berto, J. Cortijo, M. Perpina, C. Sanz and E. J. Morcillo
605
Effects of erythromycin on chemoattractant-activated human polymorphonuclear leukocytes
A. Labadla, G. Costa, E. Jimenez, D. Triguero and A. Garcla-Pascual
611
Endothelin receptor-mediated Ca 2+ mobilization and contraction in bovine oviductal arteries: comparison with noradrenaline and potassium
Y. Abu-Ghalyun, A. Masalmeh and S. AI-Khalil
621
Effects of allocryptopine, an alkaloid isolated from Glaucium arabicum on rat isolated ileum and urinary bladder
W. Zhang, H. Takeuchi, M. Kurono and M. Emaduddin
625
Ouabain-sensitive K+-dependent outward current caused by threo-[B-hydroxy-L-glutamic acid on snail neuron
T. Yoshimura, C. Kurita, T. Nagao, E. Usami, T. Nakao, S. Watanabe, J. Kobayashi, F. Yamazaki, H. Tanaka and H. Nagai
633
Effects of cAMP-phosphodiesterase isozyme inhibitor on cytokine production by lipopolysaccharide-stimulated human peripheral blood mononuclear cells
A. A. Almotrefi, M. C. Basco, A. Moorji and N. Dzimiri
639
Effects of amiodarone on ouabain binding to microsomal Na +, K+-ATPase in guinea-pig heart preparations
Y. Maruoka, Y. Ohno, H. Tanaka, H. Yasuda, K.-I. Ohtani, H. Sakamoto, A. Kawabe, C. Tamamura and M. Nakamura
645
Selective depression of the spinal polysynaptic reflex by the NMDA eceptor antagonists in an isolated spinal cord in vitro
J. P. De La Cruz, M. M6rida, J. A. Gonzlilez-Correa, P. Ortiz and F. Sfinchez de la Cuesta
651
Effects of S-adenosyl-L-methionine on blood platelet activation
M.W. Fryer and W. E. Glover
657
Effects of 4-methyl-2-aminopyridine on [3H]-noradrenaline overflow and contractility of isolated rabbit arteries
A. M. Silvlin, M. J. Abad, P. Bermejo and A. M. Villar
665
Adjuvant-carrageenan-induced inflammation in mice
H. Kr6ger, R. Miesel, A. Dietrich, M. Ohde, S. Altrichter, C. Braun and H. Ockenfels
671
Suppression of type II collagen-induced arthritis by N-acetyl-L cysteine in mice
M. Abdollahi, A.-R. Dehpour and M. Fooladgar
675
Alteration of rat submandibulary gland secretion of protein, calcium and N-acetyl-lB-D-glucosaminidase activity by lead
S. I. Chandranath
681
In vitro administration of 1713-estradiol inhibits drug-induced contractions
of the rat isolated seminal vesicle
VII
Contents K. A. Raheem, N. Ismael, A. Saad and S. EI-Sayad
687
Gluconeogenic activity in response to chronic administration of amphetamine sulphate and drug withdrawal
Vol. 29 No. 5 Rev/ews M. E. Pueyo and J.-B. Michel
691
Angiotensin 11 receptors in endothelial cells
M. Holstad, L. Jansson and S. Sandier
697
Inhibition of nitric oxide formation by aminoguanidine: an attempt to prevent insolin-dependent diabetes meUitus
G. Nocentini and A. Barzi
701
Antitumor acitvity of 2,2'-bipyridyl-6-carbothioamide: a ribonucleotide reductase inhibitor
P. I. B. Ceron and L. M. Bendhack
707
Increased contractile response induced with ouabain is abolished by thapsigargin in aorta of renal hypertensive rats
H. Nishiwaki, S. Kato and K. Takeuchi
713
Irritant action of monochloramine in rat stomachs: effects of zinc L-carnosine (polaprezinc)
R. Rodrigo and L. Thielemann
719
Effects of chronic and acute ethanol exposure on renal (Na+K)-ATPase in the rat
M. G. Vecchia, M. C. Filho, C. R. C. Fellipe, R. Curi and E. A. Newsholme
725
Acetate and propionate potentiate the antiproliferative effect of butyrate on RBL-2H3 growth
Y.-S. Lau, Y. K. Fung and T. M. Anderson
729
Antagonistic effects of isofloxythepin on dopamine D~ and Dz receptors and behaviors in rats
C. Pou, E. K. N6non6n~, T. A. Reader and A. Fargin
737
The human 5-HT1A receptor: comparison of its binding properties in transfected cells and cortical tissue
P. J. Pauwels
749
Competitive and silent antagonism of recombinant 5-HT~B receptors by amiloride
M. Mita, K. Satoh-Akimoto, K. Oishi, T. Hashimoto and M. K. Uchida
753
Inhibition of muscarinic receptor-operated Ca z+ sensitization by short-term desensitization of c~-toxin-permeabilized smooth muscle cells from guinea pig stomach
H. Honda, Y. Ikarashi, S. Yonebayashi and K. Shimizu
763
A difference in responsiveness of isolated hepatic artery, aorta, portal vein and vena cava of pig to flavin adenine dinucleotide including liver extract
K.-I. Kohno, M. Niwa, M. Nozaki, T. Uematsu and H. Fujimura
767
Role of nitric oxide in the convulsive seizures induced by fluoroquinolones coadministered with 4-biphenyl acetic acid
K. Hamada, Y. Sasaki, N. Taniguchi, H. Fukui, Y. Miyatsuka, Y. Kimura, Y. Ukai, Y. Yoshikuni and K. Kimura
771
Anticholinergic and calcium antagonistic activities of NS-21 contribute to the inhibition of rat urinary bladder contractions
G. Csaba and A. Inczefi-Gonda
779
Effect of combined neonatal imprinting by vitamin A, vitamin D3, benzypyrene and allylestrenol on adult rat thymus glucocorticoid and uterine estrogen receptors
S. De Moraes, M. T. Cavalcante, J. C. C. Carvalho and R. S. Mathias
783
Endogenous thromboxane A2 does not contribute to the contractile response of human umbilical artery strips to 5-hydroxytryptamine
~. G6k, S. 131ker, A. Hiiseyinov and A. Evin~2
789
Effect of lipoxygenase inhibitor on digoxin-induced cardiac arrhythmias in the isolated perfuesed guinea-pig heart
E. Ettemadzadeh and K. W. O. ~kkerman
793
Effect of morphine on rotational behavior of unilaterally brain-lesioned mice and rats: morphine withdrawal and development of tolerance
M. Nishimura, N. Asai, Y. Taquahashi, E. Satoh and Y. Shimziu
799
Effects of feeding conditions on sensitivity to tubocurarine of nerve-muscle preparations from the mouse
General Papers
VIII
Contents N. Nishimura, M. Matsushita, Y. Taquahashi, Y. Shimizu, E. Satoh and T. Hasegawa
805
Twitch potentiation induced by caffeine in the mouse diaphragm depends on external calcium ions in the absence of potassium ions
M. Nishimura, S. Nakamura, Y. Taquahashi, E. Satoh and Y. Shimizu
809
Effects of feeding condition after birth on the sensitivity of neuromuscular transmission of d-tubocurarine in vitro in mice
Y. Mutsukado, H. Tsuru, M. Sasa, M. Kambe and M. Yamakido
815
Nonadrenergic, noncholinergic inhibitory innervation in the longitudinal muscle of the rabbit portal vein
G. K. Matheson, A. Knowles, D. Guthrie, D. Gage, D. Weinzapfel and J. Blackbourne
823
Actions of serotonergic agents on hypothalamic-pituitary-adrenal axis activity in the rat
S. J. Hughes and M. Hollingsworth
829
Relaxin as a relaxant of the isoalted rat uterus: comparison with its mechanism of action in vivo
A. N. Goku~ra§ and E. F. Tezcan
835
Amitriptyline: a potent inhibitor of butyrylcholinestemsefrom human serum
A. Do~rul, O. Ye§ilyurt, G. Deniz and A. I§imer
839
Analgesic effects of amlodipine and its interaction with morphine and ketorolac-induced analgesia
M. P. Revuelta, B. Cantabrana and A. Hidalgo
847
Depolarization-dependent effect of flavonoids in rat uterine smooth muscle contraction elicited by CaCIz
K. W. Chiu and A. Y. L. Fung
859
The cardiovascular effects of green beans (Phaseolus aureus), common rue (Rum graveolens), and kelp (Laminaria japonica) in rats
M. Koutsoviti-Papadopoulou, G. Kounenis, G. Batzias and V. Elezoglou
863
Effect of cisapride on the isolated guinea pig gall bladder and common bile duct
G. M. Lew
869
Changes in microtubular tau protein after morphine in a cultured human neuroblastoma cell line
H..W. Suh, D.-K. Song and Y.-H. Kim
873
Effects of ginsenosides injected intrathecally or intracerebroventricularly on antinociception induced by morphine administered intracerebroventricularly in the mouse
Volume Contents Author Index Keyword Index
lII X XII
IX