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Contraindications to the pitocin drip
Selected abstracts 557
Volume 86 Number 4
present specimen with previously obtained specimens, and other technical details of the two techniques were assessed. A comparison was also made between specimens exhibiting differential diagnostic problems which were caused by an abundance of erythrocytes or leukocytes, an abundance of nonepithelial elements, or nuclei with marked hyperchromatosis.
It was concluded that the acridine-orange fluorescence technique is a superior technique for cytochemical analyses of the specimens. For research, this technique can be, in the author's opinion, an important cytochemical method. In addition, it is excellent for demonstrating microbiology. This has definite practical value in research work. For routine cytologic evaluation of specimens from the female genital tract, the acridine-orange fluorescence technique is, however, not a useful modification or substitute for the original Papanicolaou technique, for there is actually no saving of time or expense, it does not yield better accuracy, and it does not demonstrate new criteria that are significant for routine diagnostic work. It is actually more cumbersome due to the instability of the specimen. There is no reason to believe that less training is required to evaluate an acridine-orange fluorescence slide than a Papanicolaou specimen. J. Edward Hall Journal of Obstetrics and Gynaecology of the British Commonwealth Volume 69, February, 1962. *Marais, W. D.: Human Decidual Spiral Arterial Studies, p. 1. Marais: Human Decidual Spiral Arterial Studies, p. 1. The author did a gross and colposcopic examination of 11 7 fresh postpartum placentas from normal pregnancies, toxemic, nontoxemic accidental antepartum hemorrhages, and one placenta and uterus from a patient with mild pre-eclampsia who developed fatal postpartum eclampsia. He found that the spinal arterioles are distributed over the decidual surface and from the maternal inflow tract. The venous outflow was basal and marginal. There were no vascular connections between villi. The only fetal arteriovenous shunt of the placenta was in the perivascular network of vessels. The author observed that abruptio placentae was often due to an intraplacental thrombotic process which occluded a
venous outflow tract with subsequent rupture and hemorrhage. He felt that spinal arteriolar disease and its effects on the placenta were secondary to hypertension, chemical, hormonal, or metabolic dysfunction. Randall Bloomfield
J., and MacKay, R.: The Concentration of Oestrogens in Blood During Pregnancy, p. 13. Roy and MacKay: Concentration of Oestrogens in Blood During Pregnancy, p. 13. The blood concentrations of estriol, estrone, and estradiol were measured in three groups of pregnant women. Series A consisted of healthy primagravidas. In this group, the blood levels were determined at 4 week intervals from the twelfth week till term was noted. Series B was composed of healthy gravidas and multiparas between the thirty-seventh and forty-second week. Single samples were taken to determine the effect of parity. No significant difference was found. Series C con~isted of patients, with minor complaints requiring hospitalization, on whom blood was drawn at three 8 hour intervals on 3 consecutive days to determine the daily diurnal changes in blood estrogen concentration. No significant variance was found. Randall Bloomfield *Roy, E.
*Upton, R. D.: Contraindications to the Pitocin drip, p. 113. Upton: Contraindications to the Pitocin Drip, p. 113. The author reports on the management of 848 patients with oxytocin infusion with no maternal deaths and an uncorrected fetal loss of 4 per cent. The sole contraindication was gross cephalopelvic disproportion. He outlines a method of management without constant supervision. The flow of the infusion is initially set at 15 drops per minute with a concentration of 5 units per 500 mi. of 5 per cent glucose and water. This is increased by 5 units in the bottle every few hours until there is a uterine response. The fetal heart is checked and the mother observed for hypersensitivity to oxytocin during the first half hour. The management of the infusion is in the hands of a trained midwife. If she lacks adequate time for supervision of the infusion, it is replaced by 5 per cent glucose and water until she is free. Randall Bloomfield
Volume 86 Number 4
present specimen with previously obtained specimens, and other technical details of the two techniques were assessed. A comparison was also made between specimens exhibiting differential diagnostic problems which were caused by an abundance of erythrocytes or leukocytes, an abundance of nonepithelial elements, or nuclei with marked hyperchromatosis.
It was concluded that the acridine-orange fluorescence technique is a superior technique for cytochemical analyses of the specimens. For research, this technique can be, in the author's opinion, an important cytochemical method. In addition, it is excellent for demonstrating microbiology. This has definite practical value in research work. For routine cytologic evaluation of specimens from the female genital tract, the acridine-orange fluorescence technique is, however, not a useful modification or substitute for the original Papanicolaou technique, for there is actually no saving of time or expense, it does not yield better accuracy, and it does not demonstrate new criteria that are significant for routine diagnostic work. It is actually more cumbersome due to the instability of the specimen. There is no reason to believe that less training is required to evaluate an acridine-orange fluorescence slide than a Papanicolaou specimen. J. Edward Hall Journal of Obstetrics and Gynaecology of the British Commonwealth Volume 69, February, 1962. *Marais, W. D.: Human Decidual Spiral Arterial Studies, p. 1. Marais: Human Decidual Spiral Arterial Studies, p. 1. The author did a gross and colposcopic examination of 11 7 fresh postpartum placentas from normal pregnancies, toxemic, nontoxemic accidental antepartum hemorrhages, and one placenta and uterus from a patient with mild pre-eclampsia who developed fatal postpartum eclampsia. He found that the spinal arterioles are distributed over the decidual surface and from the maternal inflow tract. The venous outflow was basal and marginal. There were no vascular connections between villi. The only fetal arteriovenous shunt of the placenta was in the perivascular network of vessels. The author observed that abruptio placentae was often due to an intraplacental thrombotic process which occluded a
venous outflow tract with subsequent rupture and hemorrhage. He felt that spinal arteriolar disease and its effects on the placenta were secondary to hypertension, chemical, hormonal, or metabolic dysfunction. Randall Bloomfield
J., and MacKay, R.: The Concentration of Oestrogens in Blood During Pregnancy, p. 13. Roy and MacKay: Concentration of Oestrogens in Blood During Pregnancy, p. 13. The blood concentrations of estriol, estrone, and estradiol were measured in three groups of pregnant women. Series A consisted of healthy primagravidas. In this group, the blood levels were determined at 4 week intervals from the twelfth week till term was noted. Series B was composed of healthy gravidas and multiparas between the thirty-seventh and forty-second week. Single samples were taken to determine the effect of parity. No significant difference was found. Series C con~isted of patients, with minor complaints requiring hospitalization, on whom blood was drawn at three 8 hour intervals on 3 consecutive days to determine the daily diurnal changes in blood estrogen concentration. No significant variance was found. Randall Bloomfield *Roy, E.
*Upton, R. D.: Contraindications to the Pitocin drip, p. 113. Upton: Contraindications to the Pitocin Drip, p. 113. The author reports on the management of 848 patients with oxytocin infusion with no maternal deaths and an uncorrected fetal loss of 4 per cent. The sole contraindication was gross cephalopelvic disproportion. He outlines a method of management without constant supervision. The flow of the infusion is initially set at 15 drops per minute with a concentration of 5 units per 500 mi. of 5 per cent glucose and water. This is increased by 5 units in the bottle every few hours until there is a uterine response. The fetal heart is checked and the mother observed for hypersensitivity to oxytocin during the first half hour. The management of the infusion is in the hands of a trained midwife. If she lacks adequate time for supervision of the infusion, it is replaced by 5 per cent glucose and water until she is free. Randall Bloomfield